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Pathological and Clinical Correlation European Union-Thyroid Imaging Reporting and Data System (EU-TIRADS) Classification of Thyroid Nodules in Two University Hospitals in Cotonou

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Open Journal of Endocrine and Metabolic Diseases 2024年第2期14卷 15-25页

作者： Annelie Kerekou Hode Hubert Dedjan Fréjus Alamou Department of Endocrinology Metabolism Nutrition of National University Hospital Center-Hubert Koutoukou Maga Cotonou Bénin Department of Medicine and Medical Specialties of the Departemental University Hospital Center of Ouémé/Plateau Porto-Novo Bénin

Introduction: Since its creation in 2017 by the European community, the EU-TIRADS classification has enjoyed an excellent reputation in several countries around the world. Indeed, several studies conducted in these countries testify to the effectiveness of this tool for the management of nodular thyroid pathology. However, in Benin, the contribution of this classification has not yet been evaluated. It is therefore to overcome this inadequacy that we undertook this study. Objective: Participate in improving the diagnostic and therapeutic management of thyroid nodules at the CNHU HKM in Cotonou and at the CHUZ in Suru-Léré. Methods: This is a cross-sectional study with retrospective data collection spread over a period of 3 years 5 months, from January 2019 to May 2022 and carried out jointly in the Endocrinology Metabolism Nutrition and ORL-CCF departments of the CNHU HKM of Cotonou and in the ORL-CCF department of the CHUZ of Suru-Léré. The study population consisted of patients who consulted the University Clinic of Endocrinology Metabolism Nutrition, the University Clinic of ORL-CCF of the CNHU-HKM and the University Clinic of ORL-CCF of the CHUZ of Suru-Léré for thyroid nodule and who have had surgery. The study data was collected from patients hospitalization records using a survey form. Results: On ultrasound, according to the EU-TIRADS classification, 56.8% of nodules presented a low risk of malignancy (EU-TIRADS 3) compared to respectively 19.8%;23% and 2.5% of nodules with zero (EU-TIRADS 2), intermediate (EU-TIRADS 4) and high (EU-TIRADS 5) risk of malignancy. Regarding the performance of this classification, it is sensitive in 37.5% of cases and has a specificity of 78.5% with a PPV (Positive Predictive Value) and a NPV (Negative Predictive Value) respectively of 6.6 % and 91.6%. Furthermore, the bivariate correlations revealed that the size of the nodule was significantly associated with the malignancy of the nodule (p = 0.014) and the calculated value o

关键词： Thyroid Nodules EU-TIRADS Classification Malignancy

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Sparse and hybrid modelling of relative humidity: the Krsˇ ko basin case study

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CAAI Transactions on Intelligence Technology 2020年第1期5卷 42-48页

作者： jus Kocijan Matija Perne Bostjan Gras ic Marija Zlata Boznar Primoz Mlakar Department of Systems and Control Jozef Stefan InstituteJamova 39LjubljanaSlovenia Centre for Information Technologies and Applied Mathematics University of Nova GoricaVipavska 13Nova GoricaSlovenia MEIS d.o.o. Mali Vrh pri Smarju 78Smarje-SapSlovenia

This study describes an application of hybrid modelling for an atmospheric variable in the Krsko *** hybrid model is a combination of a physics-based and data-driven model and has some properties of both modelling *** the authors’case,it is used for the modelling of an atmospheric variable,namely relative humidity in a particular location for the purpose of using the predictions of the model as an input to the air-pollution-dispersion model for radiation *** presented hybrid model is a combination of a physics-based atmospherical model and a Gaussian-process(GP)regression *** GP model is a probabilistic kernel method that also enables evaluation of prediction *** problem of poor scalability of GP modelling was solved using sparse GP modelling;in particular,the fully independent training conditional method was *** different approaches to dataset selection for empirical model training were used and multiple-step-ahead predictions for different horizons were *** is shown in this study that the accuracy of the predicted relative humidity in the Krsko basin improved when using hybrid models over using the physics-based model alone and that predictions for a considerable length of horizon can be used.

关键词： humidity horizon modelling

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Dynamic System Identification of Underwater Vehicles Using Multi-output Gaussian Processes

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International Journal of Automation and computing 2021年第5期18卷 681-693页

作者： Wilmer Ariza Ramirez jus Kocijan Zhi Quan Leong Hung Duc Nguyen Shantha Gamini Jayasinghe Australian Maritime College University of TasmaniaNewnham 7248Australia Jozef Steftan Institute Ljubljana SI-1000Slovenia School of Engineering and Management University of Nova GoricaVipara SI-5271Slovenia

Non-parametric system identification with Gaussian processes for underwater vehicles is explored in this research with the purpose of modelling autonomous underwater vehicle(AUV) dynamics with a low amount of data. Multi-output Gaussian processes and their aptitude for modelling the dynamic system of an underactuated AUV without losing the relationships between tied outputs are used. The simulation of a first-principle model of a Remus 100 AUV is employed to capture data for the training and validation of the multi-output Gaussian processes. The metric and required procedure to carry out multi-output Gaussian processes for AUV with 6 degrees of freedom(DoF) is also shown in this paper. Multi-output Gaussian processes compared with the popular technique of recurrent neural network show that multi-output Gaussian processes manage to surpass RNN for non-parametric dynamic system identification in underwater vehicles with highly coupled DoF with the added benefit of providing the measurement of confidence.

关键词： Dependent Gaussian processes dynamic system identification multi-output Gaussian processes non-parametric identification autonomous underwater vehicle(AUV)

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自身免疫性甲状腺疾病患者外周血淋巴细胞端粒长度的研究

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中华微生物学和免疫学杂志 2001年第5期21卷 504-507页

作者：陈健萌戴为信任韵钊崔巍T om.jus 中国医学科学院中国协和医科大学北京协和医院丹麦DAKO公司

目的　研究自身免疫性甲状腺疾病 (ATD)患者外周血淋巴细胞端粒长度的变化。方法　用流式原位杂交法检测 3 8例ATD患者和 4 8例健康对照者外周血淋巴细胞的端粒长度。结果　患者组外周血淋巴细胞端粒长度明显短于健康对照组 (P <0 .0 0 ... 详细信息

目的　研究自身免疫性甲状腺疾病 (ATD)患者外周血淋巴细胞端粒长度的变化。方法　用流式原位杂交法检测 3 8例ATD患者和 4 8例健康对照者外周血淋巴细胞的端粒长度。结果　患者组外周血淋巴细胞端粒长度明显短于健康对照组 (P 0 .0 0 1 ) ,端粒长度与病程、发病时间、甲状腺激素水平不相关。健康对照组端粒长度随年龄增加而变短 ,病人组端粒长度与年龄不相关。结论ATD病人的外周血淋巴细胞端粒长度比正常人短 ,且与年龄不相关 ,提示其外周血淋巴细胞复制、分裂增多及凋亡异常。

关键词：端粒自身免疫性甲状腺疾病淋巴细胞

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Simulations of helicopter ditching using smoothed particle hydrodynamics

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Journal of Hydrodynamics 2020年第4期32卷 653-663页

作者： G.Oger A.Vergnaud B.Bouscasse J.Ohana M.Abu Zarim M.De Leffe A.Bannier L.Chiron Y.jus M.Gamier S.Halbout D.Le Touze Ecole Centrale de Nantes LHEE4 Laboratory(ECN and CNRS)NantesFrance Nextflow Software NantesFrance Bureau Veritas Solutions Marine and Offshore NantesFrance Airbus Helicopters MarseilleFrance

The present work has been performed in the context of the European H2020 project increased SAfety and Robust certification for ditching of Aircrafts and Helicopters(SARAH)dedicated to improving the safety during aircraft ditching,together with a better understanding of the physics involved during those crucial *** numerical and experimental aspects are explored during this *** present study focuses on the application of the smoothed particle hydrodynamics(SPH)method to the simulation of helicopter ditching,as this method has proved to be particularly adapted to free surface impact *** are performed for three different impact configurations,for which the numerical solutions are compared with the experimental results(forces and kinematics)obtained at the wave basin of Ecole Centrale Nantes on a mock-up shape provided by Airbus *** of sensitivity analysis are also provided when needed,to assess the role of some parameters involved in the helicopter behavior and the fluid pressure forces exerted during the impact.

关键词： Helicopter ditching smoothed particle hydrodynamics(SPH) Free surface impact wave impact numerical vs experimental solutions

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Linear scaling Coulomb interaction in the multiwavelet basis,a parallel implementation

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International Journal of Modeling, Simulation, and Scientific Computing 2014年第S1期5卷 28-50页

作者： Stig Rune Jensen Jonas jusélius Antoine Durdek Tor Fl˚a Peter Wind Luca Frediani Department of Physics and Technology Centre for Theoretical and Computational Chemistry UiT The Arctic University of Norway N-9037 TromsøNorway High Performance Computing Group Centre for Theoretical and Computational Chemistry UiT The Arctic University of Norway N-9037 TromsøNorway Department of Mathematics and Statistics Centre for Theoretical and Computational Chemistry UiT The Arctic University of Norway N-9037 TromsøNorway Department of Chemistry Centre for Theoretical and Computational Chemistry UiT The Arctic University of Norway N-9037 TromsøNorway

We present a parallel and linear scaling implementation of the calculation of the electrostatic potential arising from an arbitrary charge *** approach is making use of the multi-resolution basis of *** potential is obtained as the direct solution of the Poisson equation in its Green’s function integral *** the multiwavelet basis,the formally non local integral operator decays rapidly to negligible values away from the main diagonal,yielding an effectively banded structure where the bandwidth is only dictated by the requested *** sparse operator structure has been exploited to achieve linear scaling and parallel *** has been achieved both through the shared memory(OpenMP)and the message passing interface(MPI)*** implementation has been tested by computing the electrostatic potential of the electronic density of long-chain alkanes and diamond fragments showing(sub)linear scaling with the system size and efficent parallelization.

关键词： Multiwavelets electrostatic potentials Poisson equation integral operators linear scaling parallel implementation

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Factors Associated with Early Pregnancy among Adolescent Girls in Schools in Bohicon, Benin in 2022

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Open Journal of Obstetrics and Gynecology 2023年第11期13卷 1886-1908页

作者： Biao Mélissa Glele Ahanhanzo Yolaine Mongbo Virginie Houngnihin Roch Togonou Fréjus Assogba Christelle Association for Education Sexuality and Health in Africa (APESSA)/Regional Institute of Public Health University of Abomey-Calavi Abomey-Calavi Benin Department of Epidemiology and Biostatistics Regional Institute of Public Health University of Abomey-Calavi Abomey-Calavi Benin Department of Policies and Health Systems Regional Institute of Public Health University of Abomey-Calavi Abomey-Calavi Benin Association for Education Sexuality and Health in Africa (APESSA)/Laboratory of Applied Medical Anthropology University of Abomey-Calavi (LAMA/UAC) Abomey-Calavi Benin Association for Education Sexuality and Health in Africa (APESSA) Abomey-Calavi Benin

Introduction: The growing phenomenon of early pregnancies in Benin has adverse consequences on the lives of adolescent girls, impacting various social, health, economic, and educational aspects. This study aims to identify the factors associated with early pregnancies in the municipality of Bohicon in 2022. Materials and Methods: This is a case-control study conducted in Bohicon, involving 47 cases and 94 controls from 16 secondary and technical schools. Cases were selected exhaustively, while controls were randomly drawn from girls aged 10 to 19 in the same class who had never been pregnant. Matching was based on the type of institution and class. Data were collected through a questionnaire and analyzed using Epi info 7.***.1.0 and STATA 15 software, employing multiple conditional logistic regression (5% significance threshold) to identify factors related to early pregnancies. Results: The average age of adolescents was 17.63 years ± 0.09 for cases and 17.12 years ± 0.13 for controls. Associated factors included age over 16 years (p = 0.049), the marital status of the adolescent (single) (p = 0.001), and the monthly pocket money of the adolescent less than 10,000 FCFA (p = 0.031). Conclusion: Three factors related to early pregnancies were identified. To counteract this phenomenon and promote responsible sexuality among adolescents, it is essential to strengthen communication efforts aimed at modifying behaviors.

关键词： Early Pregnancy Schools Factors Bohicon

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小怪兽

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汽车测试报告 2015年第4期 88-95页

作者： RICHARD HAMMOND jus TIN LEIGHTON TONY

为什么？因为阁下并非1992年版JeremYClarkson；因为你看得出这里的主角是全新MX-5，知道这辆红色小跑车在江湖上真真正正举足轻重。它不单对马自达十分重要（原因显而易见，MX-5可是马自达的摇钱树），更重要的一点是MX-5乃有史以来最... 详细信息

为什么？因为阁下并非1992年版JeremYClarkson；因为你看得出这里的主角是全新MX-5，知道这辆红色小跑车在江湖上真真正正举足轻重。它不单对马自达十分重要（原因显而易见，MX-5可是马自达的摇钱树），更重要的一点是MX-5乃有史以来最畅销的双座跑车。

关键词：怪兽双座跑车马自达摇钱树

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中国公共知识分子的当下状况及重建必要

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浙江工商大学学报 2009年第6期 83-89页

作者：龚举善武汉大学文学院武汉430072

公共知识分子指那些已经并且正在思想界、科学界、社会学界和文艺学界取得一定声誉并利用这种声誉从某种世界观或某些道德伦理的角度出发有效参与社会事务监管的公共性人士。作为一种客观存在的社会文化现象,当下中国语境中的公共知识... 详细信息

公共知识分子指那些已经并且正在思想界、科学界、社会学界和文艺学界取得一定声誉并利用这种声誉从某种世界观或某些道德伦理的角度出发有效参与社会事务监管的公共性人士。作为一种客观存在的社会文化现象,当下中国语境中的公共知识分子虽然多少带有"逆介入性"和"去公共性"的苦涩意味,但它仍不失为一个具有现代蕴涵的现实课题。就其重建的必要性与可能性而言,中国的公共知识分子既生逢其时又任重道远。

关键词：公共知识分子责任担当去公共化形象重建

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模糊粗糙近似算子公理集的独立性

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模糊系统与数学 2006年第4期20卷 97-104页

作者：齐晓东尚馥娟米据生河北交通职业技术学院河北石家庄050091 河北行政学院河北石家庄050031 河北师范大学数学与信息科学学院河北石家庄050016

用双论域上的模糊关系定义了广义模糊粗糙近似算子,并讨论了近似算子的性质。用公理刻画了模糊集合值算子,各种公理化的近似算子可以保证找到相应的二元模糊关系,使得由模糊关系通过构造性方法定义的模糊粗糙近似算子恰好就是用公理定... 详细信息

用双论域上的模糊关系定义了广义模糊粗糙近似算子,并讨论了近似算子的性质。用公理刻画了模糊集合值算子,各种公理化的近似算子可以保证找到相应的二元模糊关系,使得由模糊关系通过构造性方法定义的模糊粗糙近似算子恰好就是用公理定义的近似算子。讨论了刻画各种特殊近似算子的公理集的独立性,从而给出各种特殊模糊关系所对应的模糊粗糙近似算子的最小公理集。

关键词：粗糙集模糊集近似算子公理化

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