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Clinical Data-Driven Finite Element Analysis of the Kinetics of Chewing Cycles in Order to Optimize Occlusal Reconstructions Dedicated to Professor Karl Stark Pister for his 95th birthday

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Computer Modeling in Engineering & Sciences 2021年第12期129卷 1259-1281页

作者： Simon Martinez jurgen lenz Hans Schindler Willi Wendler Stefan Rues Karl Schweizerhof Sophia Terebesi Nikolaos Nikitas Giannakopoulos Marc Schmitter Institute of Mechanics Karlsruhe Institute of Technology(KIT)KarlsruheGermany Department of Prosthodontics Dental SchoolUniversity of WurzburgWurzburgGermany Department of Prosthodontics University of HeidelbergHeidelbergGermany

The occlusal design plays a decisive role in the fabrication of dental *** and dental technicians depend on mechanical simulations of mandibular movement that are as accurate as possible,in particular,to produce interference-free yet chewing-efficient dental *** this,kinetic data must be available,i.e.,movements and deformations under the influence of forces and *** the present study,so-called functional data were collected from healthy volunteers to provide consistent information for proper *** the latter purpose,biting and chewing forces,electrical muscle activity and jaw movements were registered synchronously,and individual magnetic resonance tomograms(MRI)were *** acquired data were then added to a large complex finite element model of the complete masticatory system using the functional information obtained and individual anatomical geometries so that the kinetics of the chewing process and teeth grinding could be realistically *** allows developing algorithms that optimize computer-aided manufacturing of dental prostheses close to *** this way,a failure-free function of the dental prosthesis can be guaranteed and its damage during usage can be reduced or prevented even including endosseous implants.

关键词： Occlusal design mechanical simulations of mandibular movement finite element model of the complete masticatory system simulation of chewing process and teeth grinding

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Primary repair of esophageal atresia Gross type C via thoracoscopic magnetic compression anastomosis:Is it the best option?

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1474-1481页

作者： Sonia Pérez-Bertólez Jorge Godoy-lenz Department of Pediatric Surgery Sant Joan de Deu HospitalUniversity of BarcelonaBarcelona 08950Spain Department of Pediatric Surgery Clínica Alemana of SantiagoSantiago 7650568Chile

Magnetic compression anastomosis is a promising treatment option for patients with complex esophageal atresia;but,at the present time,should not be the first therapeutic option in those cases where the surgeon can per... 详细信息

关键词： Esophageal atresia Tracheoesophageal fistula Thoracoscopy Magnamosis Magnetic anastomosis

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The Pairing Analysis Improvement of Magnetized Structure in Electromagnetic Bulging Process in Case of Tube with Field Shaper

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Journal of Electromagnetic Analysis and Applications 2024年第4期16卷 43-67页

作者： Blaise Kevine lenz Soronga Zhanqian Zhan Jing Liu Jonas Asamoah Mohamed Bangali Bangura Matala Makiese N’kodia Kambani Chrionie Md Jobayer Hossain Yongdong Chen Program Debugging and Design Department Guangdong Lyric Robot Automation Co. Ltd Huizhou China Electrical and Automation Department China Three Gorges University Yichang China Electronic Department Power Electronic Research Center University of Kent Giles Ln Canterbury UK Program Debugging Department Guangdong Lyric Robot Automation Co. Ltd. Huizhou China Electrical and Computer Engineering Department South China University of Technology Guangzhou China World Standardization Certification and Testing Group (Shenzhen) Co. Ltd. Shenzhen China Electrical Engineering-Power System Mapon University Kindu Democratic Republic of Congo Department of Economy Managment School of Management Computer and Telecomunication Rabbat Marocco Materials Visual Calibration Department Guangdong Lyric Robot Automation Co. Ltd. Huizhou China Program Design Department Guangdong Lyric Robot Automation Co. Ltd. Huizhou China

In the current practical science, the accuracy in the formability of metal alloys being the goal when using electromagnetic forming (EMF) technology, which is a high-speed processing technology that uses Lorentz forces to achieve plastic deformation of sheet metal;according to the previous analysis, the results have shown that in most cases, the Lorentz force acting on the workpiece (metal) is not uniform, there are uneven axial deformations of the metal plates which prevent the rapid advancement of today’s technology. In this article, we presented some advanced analyzes which will lead us to improve the technical solution for the problems of non-uniform axial deformations of the metals in the traditional tube electromagnetic forming technology (EMF). A field shaper is used as a practical forming tool to influence the magnetic field and magnetic pressure distribution, thereby improving the forming ability and result during the electromagnetic forming (EMF) process and we see that induced eddy current control is realized by changing the structural parameters of the magnetic field shaper;which improves the strength and controllability of the magnetic force that acts on the workpiece;thereby a greater radial magnetic pressure can be achieved with field shaper than the case without it;the field shaper regulates the electromagnetic force, the distribution of the magnetic pressure decreases, and the uniform force area of the tube increases which effectively enhances the uniform range of the pipe electromagnetic bulging and the electromagnetic induction coupling between the coil and the metallic workpiece is generally required to produce the Lorentz forces. Using COMSOL Multiphysics® simulation software helped us to accurately represent the real world, simulating multiple physical effects that happened in this model during the process.

关键词： Electromagnetic Forming Field Shaper Lorentz Force Magnetic Pressure Distribution

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Predicting electronic structures at any length scale with machine learning

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npj Computational Materials 2023年第1期9卷 1176-1185页

作者： lenz Fiedler Normand A.Modine Steve Schmerler Dayton J.Vogel Gabriel A.Popoola Aidan P.Thompson Sivasankaran Rajamanickam Attila Cangi Center for Advanced Systems Understanding D-02826 GörlitzGermany Helmholtz-Zentrum Dresden-Rossendorf D-01328 DresdenGermany Computational Materials and Data Science Sandia National Laboratories1515 Eubank BlvdAlbuquerque 87123 NMUSA Elder Research Inc.300 West Main StreetCharlottesville 22903 VAUSA Center for Computing Research Sandia National Laboratories1515 Eubank BlvdAlbuquerque 87123 NMUSA

The properties of electrons in matter are of fundamental *** give rise to virtually all material properties and determine the physics at play in objects ranging from semiconductor devices to the interior of giant gas *** and simulation of such diverse applications rely primarily on density functional theory(DFT),which has become the principal method for predicting the electronic structure of *** DFT calculations have proven to be very useful,their computational scaling limits them to small *** have developed a machine learning framework for predicting the electronic structure on any length *** shows up to three orders of magnitude speedup on systems where DFT is tractable and,more importantly,enables predictions on scales where DFT calculations are *** work demonstrates how machine learning circumvents a long-standing computational bottleneck and advances materials science to frontiers intractable with any current solutions.

关键词： electronic interior frontier

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Ischemic long-term-potentiation(iLTP): perspectives to set the threshold of neural plasticity toward therapy

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Neural Regeneration Research 2015年第10期10卷 1537-1539页

作者： Maximilian lenz Andreas Vlachos Nicola Maggio Department of Neurology The J.Sagol Neuroscience Center The Chaim Sheba Medical Center Institute of Clinical Neuroanatomy Neuroscience Center Frankfurt Goethe-University Frankfurt Talpiot Medical Leadership Program The Chaim Sheba Medical Center

The precise role of neural plasticity under pathological conditions remains not well understood. It appears to be well accepted, however, that changes in the ability of neurons to express plasticity accompany neurological diseases. Here, we discuss recent experimental evidence, which suggests that synaptic plasticity induced by a pathological stimulus, i.e., ischemic long-term-potentiation（i LTP） of excitatory synapses, could play an important role for post-stroke recovery by influencing the post-lesional reorganization of surviving neuronal networks.

关键词： ischemic LTP(iLTP) stroke neural repair synaptic plasticity neural homeostasis

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Geomorphological mapping for the valorization of the alpine environment. A methodological proposal tested in the Loana Valley(Sesia Val Grande Geopark, Western Italian Alps)

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Journal of Mountain Science 2017年第6期14卷 1023-1038页

作者： Irene BOLLATI Beatrice CROSA lenz Enrico ZANOLETTI Manuela PELFINI Earth Science Department 'A. Desio' Universita degli Studi diMilano Via Mangiagalli 34 20133 - Milan Italy C-eoexplora-C-eologia & Outdoor Via Mussi 5 28831-Baveno (VB) Italy

Geomorphological mapping plays a key role in landscape representation: it is the starting point for many applications and for the realization of thematic maps, such as hazard and risk maps, geoheritage and geotourism maps. Traditional geomorphological maps are useful for scientific purposes but they need to be simplified for different aims as management and education. In tourism valorization, mapping of geomorphological resources(i.e., geosites, and geomorphosites), and of geomorphic evidences of past hazardous geomorphological events, is important for increasing knowledge about landscape evolution and active processes, potentially involving geomorphosites and hiking trails. Active geomorphosites, as those widespread in mountain regions, testify the high dynamicity of geomorphic processes and their link with climatic conditions. In the present paper, we propose a method to produce and to update cartographic supports(Geomorphological Boxes)realized starting from a traditional geomorphological survey and mapping. The Geomorphological Boxes are geomorphological representation of single, composed or complex landforms drawn on satellite images, using the official Italian geomorphological legend(ISPRA symbols). Such cartographic representation is also addressed to the analysis(identification, evaluation and selection) of Potential Geomorphosites and Geotrails. The method has been tested in the upper portion of the Loana Valley(Western Italian Alps), located within the borders of the Sesia Val Grande Geopark, recognized by UNESCO in 2013. The area has a good potential for geotourism and for educational purposes. We identified 15 Potential Geomorphosites located along 2 Geotrails; they were ranked according to specific attributes also in relation with a Reference Geomorphosite located in the Loana hydrographic basin and inserted in official national and regional databases of geosites(ISPRA; Regione Piemonte). Finally, the ranking of Potential Geomorphosites allowed to selec

关键词：地貌制图阿尔卑斯山地质公园 Grande 意大利高寒环境稳定西亚

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Ultra-dense planar metallic nanowire arrays with extremely large anisotropic optical and magnetic properties

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Nano Research 2018年第7期11卷 3519-3528页

作者： Qi Jia Xin Ou Manuel Langer Benjamin Schreiber Jorg Grenzer Pablo F. Siles Raul D. Rodriguez Kai Huang Ye Yuan Alireza Heidarian Rene Hubner Tiangui You Wenjie Yu Kilian lenz jurgen Lindner Xi Wang Stefan Facsko Helmholtz-Zentrum Dresden-Rossendorf Institute of Ion Beam Physics and Materials Research Bautzner Landstr. 400 01328 Dresden Germany State Key Laboratory of Functional Material for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Shanghai 200050 China Technische Universitat Chemnitz ReichenhainerstraBe 70 09107 Chemnitz Germany University of Chinese Academy of Sciences Beijing 100049 China Tomsk Polytechnic University 30 Lenin Ave. 634050 Tomsk Russia

A nanofabrication method for the production of ultra-dense planar metallic nanowire arrays scalable to wafer-size is presented. The method is based on an efficient template deposition process to grow diverse metallic nanowire arrays with extreme regularity in only two steps. First, Ⅲ-Ⅴ semiconductor substrates are irradiated by a low-energy ion beam at an elevated temperature, forming a highly ordered nanogroove pattern by a ＂reverse epitaxy＂ process due to self-assembly of surface vacancies. Second, diverse metallic nanowire arrays （Au, Fe, Ni, Co, FeAl alloy） are fabricated on these Ⅲ-Ⅴ templates by deposition at a glancing incidence angle. This method allows for the fabrication of metallic nanowire arrays with periodicities down to 45 nm scaled up to wafer-size fabrication. As typical noble and magnetic metals, the Au and Fe nanowire arrays produced here exhibited large anisotropic optical and magnetic properties, respectively. The excitation of localized surface plasmon resonances （LSPRs） of the Au nanowire arrays resulted in a high electric field enhancement, which was used to detect phthalocyanine （CoPc） in surface-enhanced Raman scattering （SERS）. Furthermore, the Fe nanowire arrays showed a very high in-plane magnetic anisotropy of approximately 412 mT, which may be the largest in-plane magnetic anisotropy field yet reported that is solely induced via shape anisotropy within the plane of a thin film.

关键词： self-assembly metallic nanowire array reverse epitaxy magnetic anisotropy anisotropic dieledric function

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Comparative analysis of clinicopathological correlations of cyclooxygenase-2 expression in resectable pancreatic cancer

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World Journal of Gastroenterology 2010年第15期16卷 1879-1884页

作者： Marketa Hermanova Petr Karasek Jiri Tomasek Jiri lenz Jiri Jarkovsky Petr Dite First Department of Pathologic Anatomy Medical Faculty of Masaryk University St. Anne’s University Hospital Department of Complex Oncology Care Masaryk Memorial Cancer Institute Institute of Biostatistics and Analyses Masaryk University Department of Gastroenterology Medical Faculty of Masaryk University and The Faculty Hospital Brno

AIM:To perform a comparative analysis of clinicopathological correlations of cyclooxygenase2 (COX2) expression in pancreatic cancer, examined by monoclonal and polyclonal ***: The COX2 expression in 85 resection specimens of pancreatic ductal adenocarcinoma was immunohistochemically examined using both monoclonal and polyclonal antibodies. The final immunoscores were obtained by multiplying the percentage of positive cells with the numeric score reflecting the staining ***2 expression levels were classified into three categories (0, 1+, and 2+) and the clinicopathological correlations were statistically evaluated and ***: The positive tumor expression rates of COX2 were 80.5% using monoclonal antibody and 69.4% using polyclonal antibody. In the KaplanMeier analysis, no significant correlations were found between levels of COX2 expression and overall survival (OS), but trends to longer OS were found in COX2 negative cases using monoclonal antibody. Significantly longer disease free survival was revealed in COX2 negative cases using monoclonal antibody (P = 0.019). No correlations between COX2 expression levels and grade (G), tumor (T) status and nodal (N) status were demonstrated. Low histological grade showed a strong association with a longer OS (P < 0.001). Correlation of survival and T status revealed a shorter OS in T3 tumors, but the results reached only marginal statistical significance (P = 0.070). In the multivariate Cox proportional hazards regression model, histological grade, T and N status remained valuable predictors of a worse survival with borderline significance for T [hazards ratio (HR) = 4.18 for G (if G = 3, P < 0.001); HR = 1.64 for T (if T = 3, P = 0.065); HR = 2.53 for N (if N = 1, P = 0.006)]. Higher grade, T or N status was associated with a worse OS. CONCLUSION: The immunohistochemically assessed level of COX2 expression does not seem to represent a valuable independent prognostic factor and is not super

关键词： Pancreatic cancer Cyclooxygenase2 Immunohistochemistry Monoclonal antibody Polyclonal antibody

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POLY (β-HYDROXYALKANOATES): NATURAL BIOCOMPATIBLE AND BIODEGRADABLE POLYESTERS PRODUCED BY BACTERIA

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Chinese Journal of Polymer Science 1989年第4期7卷 289-298页

作者： ROBERT W. lenz RICHARD A. GROSS HELMUT BRANDL R. CLINTON FULLER Department of Polymer Science and Engineering University of MassachusettsAmherstMA 01003USADepartment of ChemistryUniversity of Lowell1 University Ave.LowellMA 01854USAInstitute for Plant BiologyZollikerstrasse 1078008 ZurichSwitzerlandDepartment of BiochemistryUniversity of MassachusettsAmherstMA 01003USA

A wide variety of different types of microorganisms are known to produce intracellular energy and carbon storage products, which have been generally described as being poly (β-hydroxybutyrate), PHB, but which are, more often than not, copolymers containing different alkyl groups at the β-position. Hence, PHB belongs to the family ofpoly (β-hydroxyalkanoastes), PHA, all of which are usually formed as intracellular inclusions in bacteria under unbalanced growth conditions. Recently, it became of industrial interest to evaluate these PHA polyesters as natural biodegradable and biocompatible plastics for a wide range of possible applications, such as surgical sutures or packaging containers. For industrial applications, the controlled incorporation of repeating units with different chain lengths into a series of copolymers is desirable in order to produce polyesters with a range of material properties because physical and chemical characteristics depend strongly on the polymer composition. Such 'tailor-made' copolymers can be produced under controlled growth conditions in that, if a defined mixture of substrates for a certain type of microorganisms is supplied, a well defined and reproducible copolymer is formed.

关键词： PHB POLY HYDROXYALKANOATES NATURAL BIOCOMPATIBLE AND BIODEGRADABLE POLYESTERS PRODUCED BY BACTERIA

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DISTRIBUTION AND RESPONSE EVOKED BY MICROSTIMULATION OF THALAMUS NUCLEI IN PATIENTS WITH DYSTONIA AND TREMOR

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Chinese Medical Journal 1994年第4期 27-32页

作者：林岩崇 FniderickA.lenz DepartmentofNeurosurgery FirstHospitalWenzhouMedicalCollege DepartmentofNeurosurgery JohnsHopkinsUniversityUSATheeffectof806microstimulationswereobservedin16patientsmotorresponsewasseenat19sitestheresponsewithincreaseddystoniawasseenat28sites.

The effect of 806 microstimulations were observed in 16 patients motor response was seen at 19 sites,the response with increased dystonia was seen at 28 sites.

关键词： TR DA 口口 DISTRIBUTION AND RESPONSE EVOKED BY MICROSTIMULATION OF THALAMUS NUCLEI IN PATIENTS WITH DYSTONIA AND TREMOR

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