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Mechanical behavior and response mechanism of porous metal structures manufactured by laser powder bed fusion under compressive loading

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 737-749页

作者： Xuanming Cai Yang Hou Wei Zhang Zhiqiang Fan Yubo Gao junyuan wang Heyang Sun Zhujun Zhang Wenshu Yang School of Aerospace Engineering North University of ChinaTaiyuan 030051China School of Materials Science and Engineering North University of ChinaTaiyuan 030051China School of Astronautics Harbin Institute of TechnologyHarbin 150080China School of Mechanical Engineering North University of ChinaTaiyuan 030051China Shijiazhuang Campus Army Engineering University of PLAShijiazhuang 050003China 65589 Unit 91 Detachment Daqing 163411China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150080China

Al Si10Mg porous protective structure often produces different damage forms under compressive loading,and these damage modes affect its protective *** order to well meet the service requirements,there is an urgent need to comprehensively understand the mechanical behavior and response mechanism of AlSi10Mg porous structures under compressive *** this paper,Al Si10Mg porous structures with three kinds of volume fractions are designed and optimized to meet the requirements of high-impact,strong-energy absorption,and lightweight *** mechanical behaviors of AlSi10Mg porous structures,including the stress-strain relationship,structural bearing state,deformation and damage modes,and energy absorption characteristics,were obtained through experimental studies at different loading *** damage pattern of the damage section indicates that AlSi10Mg porous structures have both ductile and brittle mechanical *** simulation studies show that the AlSi10Mg porous structure undergoes shear damage due to relative misalignment along the diagonal cross-section,and the damage location is almost at 45°to the load direction,which is the most direct cause of its structural damage,revealing the damage mechanism of AlSi10Mg porous structures under the compressive *** normalized energy absorption model constructed in the paper well interprets the energy absorption state of Al Si10Mg porous structures and gives the sensitive location of the structures,and the results of this paper provide important references for peers in structural design and optimization.

关键词： AlSi10Mg additive manufacture energy absorption characteristics damage by deformation mechanical behavior

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Computer-aided molecular design and optimization of potent inhibitors disrupting APC-Asef interaction

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2631-2645页

作者： Xuefei wang Zeqian Du Yuegui Guo Jie Zhong Kun Song junyuan wang Jianqiang Yu Xiuyan Yang Chen-Ying Liu Ting Shi Jian Zhang Department of Pathophysiology Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationShanghai Jiao Tong UniversitySchool of MedicineShanghai 200025China Key Laboratory of Protection Development and Utilization of Medicinal Resources in Liupanshan AreaMinistry of EducationPeptide&Protein Drug Research CenterSchool of PharmacyNingxia Medical UniversityYinchuan 750004China State Key Laboratory of Microbial Metabolism Joint International Research Laboratory of Metabolic and Developmental SciencesSchool of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China Department of Colorectal and Anal Surgery Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Basic Science Research Center Base(Pharmaceutical Science) Yantai UniversityYantai 264005China Medicinal Chemistry and Bioinformatics Center Shanghai Jiao Tong UniversitySchool of MedicineShanghai 200025China State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjing 210023China

Colorectal cancer(CRC)is the second leading cause of cancer mortality *** initial diagnosis,approximately 20%of patients are diagnosed with metastatic CRC(mCRC).Although the APC-Asef interaction is a well-established target for mCRC therapy,the discovery and development of effective and safe drugs for mCRC patients remains an urgent and challenging *** this study,we identified a novel structural scaffold based on MAI inhibitors,the first-in-class APC-Asef inhibitors we reported *** model-driven optimizations of the N-terminal cap and experimental evaluations of inhibitory activity were performed,and 24-fold greater potency was obtained with the best inhibitor compared to the parental *** addition,the cocrystal structure validated that the two-layerπ-πstacking interactions were essential for inhibitor stabilization in the bound ***,in vitro and in vivo studies have demonstrated that novel inhibitors suppressed lung metastasis in CRC by disrupting the APC-Asef *** results provide an intrinsic structural basis to further explore drug-like molecules for APC-Asef-mediated CRC therapy.

关键词： APC-Asef Peptidomimetic Computer-aided molecular design ONIOM model π-πstacking Metastatic colorectal cancer

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AlSi10Mg多孔结构在不同加载应变率下的损伤模式及响应机制

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金属学报 2024年第7期60卷 857-868页

作者：蔡宣明张伟范志强高玉波王俊元张柱军中北大学航空宇航学院太原030051 哈尔滨工业大学航天学院哈尔滨150080 中北大学机械工程学院太原030051 65589部队91分队大庆163411

为探明AlSi10Mg多孔结构在不同加载应变率条件下的承载能力、破坏模式及破坏机理,展开了一系列实验研究、理论分析和数值模拟。通过实验研究明确了该AlSi10Mg多孔结构的损伤破坏模式主要表现为损伤断裂和剪切破坏,且其力学行为对加载应... 详细信息

为探明AlSi10Mg多孔结构在不同加载应变率条件下的承载能力、破坏模式及破坏机理,展开了一系列实验研究、理论分析和数值模拟。通过实验研究明确了该AlSi10Mg多孔结构的损伤破坏模式主要表现为损伤断裂和剪切破坏,且其力学行为对加载应变率不敏感。结合结构损伤分析和高精度数值模拟研究,发现AlSi10Mg多孔结构在轴向压缩载荷作用下沿斜截面相对错动而发生剪切破坏,这一失效模式是导致其结构发生断裂破坏的最直接原因。结合实验研究和理论分析表明,当AlSi10Mg多孔结构应变小于10%时,其在低应变率和中应变率下的吸能特性十分接近;当结构应变大于10%时,其在中应变率下的吸能特性略高于低应变率加载时。在不同高应变率(378~1639 s^(-1))加载条件下,该AlSi10Mg多孔结构吸能特性十分接近。

关键词：多孔结构选区激光熔化力学行为能量吸收剪切失效

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New repairable system model with two types repair based on extended geometric process

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Journal of Systems Engineering and Electronics 2019年第3期30卷 613-623页

作者： wang junyuan YE Jimin XIE Pengfei School of Mathematics and Statistics Xidian University

A simple repairable system with one repairman is considered. As the system working age is up to a specified time T, the repairman will repair the component preventively, and it will go back to work as soon as the repair finished. When the system failure, the repairman repair it immediately. The time interval of the preventive repair and the failure correction is described with the extended geometric process. Different from the available replacement policy which is usually based on the failure number or the working age of the system, the bivariate policy (T,N) is considered. The explicit expression of the long-run average cost rate function C(T,N) of the system is derived. Through alternatively minimize the cost rate function C(T,N), the optimal replacement policy (T?,N?) is obtained, and it proves that the optimal policy is unique. Numerical cases illustrate the conclusion, and the sensitivity analysis of the parameters is carried out.

关键词： extended geometric process average cost rate replacement policy renewal reward theorem

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A generalized geometric process based repairable system model with bivariate policy

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Journal of Systems Engineering and Electronics 2021年第3期32卷 631-641页

作者： MA Ning YE Jimin wang junyuan College of Mathematics and Statistics Xidian UniversityXi’an 710071China College of Sciences China Jiliang UniversityHangzhou 310018China

The maintenance model of simple repairable system is *** assume that there are two types of failure,namely type Ⅰ failure(repairable failure)and type Ⅱ failure(irrepairable failure).As long as the type Ⅰ failure occurs,the system will be repaired immediately,which is failure repair(FR).Between the(n-1)th and the nth FR,the system is supposed to be preventively repaired(PR)as the consecutive working time of the system reaches λ^(n-1) T,where λ and T are specified ***,we assume that the system will go on working when the repair is finished and will be replaced at the occurrence of the Nth type Ⅰ failure or the occurrence of the first type Ⅱ failure,whichever occurs *** practice,the system will degrade with the increasing number of *** is,the consecutive working time of the system forms a decreasing generalized geometric process(GGP)whereas the successive repair time forms an increasing GGP.A simple bivariate policy(T,N)repairable model is introduced based on *** alternative searching method is used to minimize the cost rate function C(N,T),and the optimal(T,N)^(*) is ***,numerical cases are applied to demonstrate the reasonability of this model.

关键词： renewal reward theorem generalized geometric process(GGP) average cost rate optimal policy replacement

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Carburized Effect on Gradient Cemented Carbide of TiC/TaC Prepared by Liquid Phase Sintering

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Journal of Wuhan University of Technology(Materials Science) 2016年第4期31卷 891-895页

作者：邵延君 li xing wang jianqing wang junyuan School of Mechanical and Power Engineering North University of China Taiyuan 030051 China

The carburized graded cemented carbide with the addition of some（Ti,Ta） C was analyzed in *** micro-structure and element distribution were measured by using optical microscopy and X-ray photoelectron spectrometry along the gradient *** experimental results showed that a large amount of solid solution phases were formed and distributed like clusters in the surface layer of cemented *** cobalt migration was not very notable and the Co-rich layer was close to the surface of cemented carbide.

关键词： carbide photoelectron migration Sintering notable graded constantly dissolved morethan additives

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The Properties of the Sintered Copper Powder Liner

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Journal of Wuhan University of Technology(Materials Science) 2014年第2期29卷 269-272页

作者：段能全 GAO Yonghong wang junyuan DU Wenhua wang Fengying School of Mechanical and Power Engineering North University of China School of Chemical Engineering and Environment North University of China

In order to study the properties of sintered copper powder shaped charge liner, the copper powder, whose particle size was below 20 μm, was chosen as the main material. The mixed powders were directly pressed into the desired shape of the shaped charge liner by the top direct-pressure way. The microscopic morphology of the spinning shaped charge liner, the sintered and non-sintered powder liners, and the particle properties of the copper powder were studied with scanning electron microscopy. The expe^mental results showed that the irregular copper powder could get together effectively and sintering could improve the compactness of the powder liner effectively. The wall thickness and density of the non-sintered and sintered liner were also tested, and it shows that sintering causes the wall thickness thinned and the density improved. The penetration depths of non-sintered powder liner, sintered powder liner and the spinning copper plate liner were tested with different standoff respectively, showing that the penetration properties of sintered powder liner are well.

关键词： irregular copper powder powder shaped charge liner sintering penetration

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Carbide Coating Preparation of Hot Forging Die by Plasma Processing

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Journal of Wuhan University of Technology(Materials Science) 2012年第6期27卷 1110-1114页

作者：杜文华 DU Cong wang Huachang wang Hongfu wang junyuan School of Mechanical Engineering and Automation North University of China School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China

To meet the performance requirements of hot forging die heat resistant layer, the Ni60-SiC coating, Ni60-Cr3C2 coating, and Ni60-WC coating were prepared using W6Mo5Cr4V2 as substrate material with 30%SiC, 10%Cr3C2, 30%WC powder by means of plasma spraying and plasma spray re-melting and plasma spray welding, respectively. Microstructure of each carbide coating was analyzed, micro-hardness was tested, and mainly thermal parameters of coating were detected. The experimental results show that using plasma spray welding, the performance of 70%Ni60/30%SiC powder is the best, and its micro-hardness can achieved 1100HV, showing good thermal-physical property.

关键词： hot forging die plasma processing Ni60-SiC Ni60-Cr3C2 Ni60-WC

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面向电力设备的T型梁电磁式振动能量采集器设计

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中国测试 2024年第5期50卷 114-121页

作者：张明皓宋睿张鋆周晨媛王俊元李运甲中国电力科学研究院有限公司北京100192 西安交通大学电气工程学院陕西西安710049

由于电网设备振动能量广泛存在,在监测设备运行状态的过程中,振动能量采集器将振动能量作为其监测装置电源的有效补充,可延长装置的运行时间。该文研究能量采集器基于刚柔结合结构,采用聚酰亚胺T型梁和FR4拾振平面线圈。刚柔结合结构使... 详细信息

由于电网设备振动能量广泛存在,在监测设备运行状态的过程中,振动能量采集器将振动能量作为其监测装置电源的有效补充,可延长装置的运行时间。该文研究能量采集器基于刚柔结合结构,采用聚酰亚胺T型梁和FR4拾振平面线圈。刚柔结合结构使能量采集器件可基于标准工业工艺批量生产,T型梁设计可有效减少加工工艺的残余应力,柔性梁使其可在低环境振动下实现较高的振幅和能量采集效率。对于该采集器进行测试后,得出T型梁器件的固有频率为140 Hz,在±1g加速度下可输出电压9.40 mV,外接匹配电阻2.31Ω后,输出功率为4.71μW。因此,该器件的固有频率位于电力系统设备振动频率的频率区间内并提供一定的输出电压和功率,从而可以有效采集其电力设备的振动能量,并实现对于设备振动特征的监测。

关键词：传感器能量采集设备振动电磁式梁结构

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Volatility Estimation of Multivariate ARMA-GARCH Model

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Journal of Harbin Institute of Technology(New Series) 2020年第1期27卷 36-43页

作者： Pengfei Xie Jimin Ye junyuan wang School of Mathematics and Statistics Xidian University

GARCH models play an extremely important role in financial time ***,the parameter estimation of the multivariate GARCH model is challenging because the parameter number is square of the dimension of the *** this paper,the model of structural vector autoregressive moving⁃average(ARMA)with GARCH is discussed and an efficient multivariate impulse response estimation method is ***,the causal structure of the model was identified and the independent component of error term vector was estimated by DirectLiNGAM ***,the relationship between conditional heteroscedasticity of the independent component of error term vector and that of residual vector was constructed,and the estimation of the impulse response of conditional volatility of multivariate GARCH models was translated to the estimation of the impulse response of error term *** independency among the independent components was translated to the impulse response estimation of the univariate case and the causal structure was ***,the proposed estimation method was used to estimate the volatility of stock market,which proved that the method is computational efficient.

关键词： structural autoregressive moving⁃average multivariate GARCH independent component causal structure volatility

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