检索结果-南通市图书馆

Boosted sustained-release with iron-based MoF-derived mesoporouscarbon-spheres as a nitroimidazole drugs carrier

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第3期86卷 269-280页

作者： Danping Wu Jiaying Zou junyi Chen Yan Li Na Ma wei Dai College of Chemistry and Materials Science Zhejiang Normal UniversityJinhua321004China College of Life Sciences Zhejiang Normal UniversityJinhua321004China College of g.ography and Environmental Sciences Zhejiang Normal UniversityJinhua321004China

Metal-organic framework(MoF)with a buildable internal structure has aroused great interest focus as self-sacrificing precursors of porous carbon(PC).However,as a drug carrier,the MoF-derived PC developed thus far are generally composed of irregular powder shape due to their crystalline nature,which consequently causing the cerebral infarction,cerebral thrombosis,and other blood *** this article,we propose a novel approach to constructing amorphous carbon microspheres(AcMs)by dis-torting the topological network through hydrothermal treatment precursors of MIL-101(Fe).then,a distinctive MIL-101(Fe)-derived spherical porous carbons(MSPC)is achieved through high temperature calcination toward *** of the glucose initial concentration and hydrothermal treatment time on the sphericity of the as-prepared mesoporous MsPC were investigated in *** the loading capacities and sustained-release performances of nitroimidazole drugs over MsPC through simulation internal environment of human body at different pH values was systematically *** nitro-imidazole drugs loading rate and release time of MsPC are 10% and 17 h under preferred ***,the MSPC exhibited very low toxicity on Hela cells and 293t cells at the concentrations tested(10-800μg mL^(-1)).this study,therefore,supports the potential of the mesoporous carbon spheres as a carrierfor nitroimidazole drug delivery.

关键词： ornidazole Metronidazole Carbon spheres Sustained-release performance Biocompatibility

A Practical Regular LDPC Coded Scheme for Physical-Layer Information Security

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2024年第5期21卷 190-201页

作者： Du junyi CEtC Key Laboratory of Avionic Information System Southwest China Institute of Electronic TechnologyChengdu 610036China

In this paper,we aim to design a practical low complexity low-density parity-check(LDPC)coded scheme to build a secure open channel and protect information from *** this end,we first propose a punctured LDPC coded scheme,where the information bits in a codeword are punctured and only the parity check bits are transmitted to the *** further propose a notion of check node type distribution and derive multi-edge type extrinsic information transfer functions to estimate the security performance,instead of the well-known weak metric bit error *** optimize the check node type distribution in terms of the signal-to-noise ratio(SNR)gap and modify the progressive edge g.owth algorithm to design finite-length *** results show that our proposed scheme can achieve a lower computational complexity and a smaller security gap,compared to the existing scrambling and puncturing schemes.

关键词： extrinsic information transfer function physical layer scheme secure open channel security gap

Laser Wire Additive Manufacturing.of ti-6Al-4V Alloy and Its Machine Learning Study for Parameters optimization(Invited)

在线全文

学校读者我要写书评

暂无评论

中国激光 2024年第4期51卷 182-198页

作者： Wu junyi Zhang Bo Wang weihua Li weipeng Yao Xiyu Wang Dawei Xing wei Yan Ming Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055GuangdongChina Songshan Lake Materials Laboratory Dongguan 523830GuangdongChina Institute of Physics Chinese Academy of SciencesBeijing 100190China Jiaxing Research Institute Southern University of Science and TechnologyShenzhen 518055GuangdongChina High Performance Computing Department National Supercomputing CenterShenzhen 518055GuangdongChina

ti-6Al-4V is a benchmark ti alloy. Laser wire additive manufacturing(LWAM) offers advanced manufacturing capability to the alloy for applications possibly including exploration of outer space. As a typical multiple-variable process, LWAM is complex, which, however, can be analyzed, predicated or even optimized by artificial intelligence(AI) methods such as machine learning(ML). In this study, printing parameters of the ti-6Al-4V is firstly optimized using single-track-single-layer experiments, and then single-track-multiple-layer samples are printed, whose properties in terms of hardness and compressive strength are analyzed subsequently by both experiments and ML. the two ML approaches, artificial neural network(ANN) and support vector machine(SVM), are employed to predict the experimental results, whose coefficients of determination R2 show g.od values. Further optimized properties are realized by adopting genetic algorithm(gA) and simulated annealing(SA) approaches, which contribute to high mechanical properties achieved, for instance, an engineering compressive strength of about 1694 MPa. the results here indicate that important mechanical properties of the LWAM-prepared ti alloys can be well predicted and enhanced using suitable ML approaches.

关键词： artificial printing additive

Bioinspired nanomaterials for wearable sensing and human–machine interfacing

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第2期17卷 445-461页

作者： Vishesh Kashyap junyi Yin Xiao Xiao Jun Chen Department of Bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA Department of Mechanical and Aerospace Engineering University of CaliforniaLos AngelesLos AngelesCA 90095USA

the inculcation of bioinspiration in sensing and human–machine interface(HMI)technologies can lead to distinctive characteristics such as conformability,low power consumption,high sensitivity,and unique properties like self-healing,self-cleaning,and *** sensing and HMI are fields rife with opportunities for the application of bioinspired nanomaterials,particularly when it comes to wearable sensory systems where biocompatibility is an additional *** review discusses recent development in bioinspired nanomaterials for wearable sensing and HMIs,with a specific focus on state-of-the-art bioinspired capacitive sensors,piezoresistive sensors,piezoelectric sensors,triboelectric sensors,magnetoelastic sensors,and electrochemical *** also present a comprehensive overview of the challenges that have hindered the scientific advancement in academia and commercialization in the industry.

关键词： bioinspired nanomaterials human–machine interface wearable sensors wearable bioelectronics

the earliest evidence for a microblade adaptation in the remote,high altitude reg.ons of the tibetan Plateau

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第5期67卷 1561-1573页

作者： Yingshuai JIN Xiaoling ZHAng Shejiang WAng junyi gE wei HE Wa DA Yunyao tAN Ziyi YAng Christopher MoRgAN Xing g.o Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of SciencesBeijing 100044China University of the Chinese Academy of Sciences Beijing 100049China Cultural Relics Conservation Institute of the Xizang Autonomous Reg.on Lhasa 850000China Nagqu Culture and tourism Bureau Nagqu 852000China University of Nevada Reno 89557USA

Microblade assemblages are among the most common prehistoric archaeological materials found on the tibetan Plateau(tP)and are thought to indicate large scale migration to and settlement of the *** microblade sites,however,have been systematically excavated,especially in the remotest,highest-elevation reg.ons of the *** timing.of the large-scale arrival,spread,and permanent settlement of people on the tP therefore remains *** this paper,we report on a recently excavated site,Locality 3 of the Nwya Devu Site(ND3),located at 4600 meters above sea level(masl),near the shore of ngoin Lake,on the interior *** analyses reveal a fairly typical microblade technological orientation and two types of microblade cores:wedge-shaped and semi-conical,which are similar to those found throug.out North *** optically Stimulated Luminescence(oSL)dating and AMS^(14)C dating,the age of ND3 ranges from 11 to 10 *** date range indicates ND3 is the oldest microblade site yet recorded in the remote,high-elevation reg.ons of the tP and thus provides important information about when and how hunter-gatherers using microblades began exploiting the higher altitudes of the *** together,studies at ND3 and throug.out the tP suggest that a microblade adaptation is associated with the first prolonged human occupation of the plateau and that microblades played a significant role in mediating the risks and facilitating the mobility necessary to permanently inhabit the tP.

关键词： the interior of tibetan Plateau Nwya Devu locality 3 Microblade Early Holocene High altitude adaption

High-Superelasticity Niti Shape Memory Alloy by Directed Energy Deposition-Arc and Solution Heat treatment

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 132-144页

作者： junyi Ma Lin Yu Qing Yang Jie Liu Lei Yang State Key Laboratory of Materials Processing and Die&Mould technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430070China School of transportation and Logistics Engineering Wuhan University of TechnologyWuhan430074China

Directed energy deposition-arc(DED-Arc)technology has the advantages of simple equipment,low manufacturing cost and high deposition rate,while the use of DED-Arc has problems of microstructure inhomogeneity,position dependence of macroscopic mechanical properties and ***,it is necessary to carry out a subsequent heat treatment to improve its microstructure uniformity,mechanical properties and *** this investigation,the DED-Arc 15-layer Niti alloy thin-walled parts with the solution treatment at different process parameters were studied to analyze the effects of solution heat treatment on microstructure,phase composition,phase transformation,microhardness,tensile and *** temperature range of solution treatment is 800-1050℃,and the treatment time range is 1-5.5 *** results show that after solution treatment at 800℃/1 h,the content of precipitated phase decreases,the grain is refined,the microhardness increases,and the mechanical properties in the 0°direction are *** strain recovery rate after 10 tensile cycles has increased from 37.13%(as-built)to 49.25%(solid solution treatment).this research provides an effective post treatment method for high-performance DED-Arc Niti shape memory alloys.

关键词： Directed energy deposition-arc(DED-Arc) Cold metal transfer(CMt) Niti shape memory alloys Microstructure Phase transformation Solution heat treatment

Versatile strategies for adult neurogenesis:avenues to repair the injured brain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 774-780页

作者： junyi Zhao Siyu Liu Xianyuan Xiang Xinzhou Zhu the Brain Cognition and Brain Disease Institute(BCBDI) Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Faculty of Life and Health Sciences Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions

Brain injuries due to trauma or stroke are major causes of adult death and ***,few interventions are effective for post-injury repair of brain *** a long debate on whether endogenous neurogenesis actually happens in the adult human brain,there is now substantial evidence to support its *** neurogenesis is usually significantly stimulated by injury,the reparative potential of endogenous differentiation from neural stem/progenitor cells is usually ***,exogenous stem cell transplantation has shown promising results in animal models,but limitations such as poor long-term survival and inefficient neuronal differentiation make it still challenging for clinical ***,a high focus was placed on glia-to-neuron conversion under single-factor *** some inspiring results,the validity of this strategy is still *** this review,we summarize historical findings and recent advances on neurogenesis strategies for neurorepair after brain *** also discuss their advantages and drawbacks,as to provide a comprehensive account of their potentials for further studies.

关键词： adult neurogenesis glia-to-neuron conversion ischemic stroke neurogenic niche neuroinflammation stem cell transplantation traumatic brain injury

Amplified internal electric field of Cs_(2)CuBr_(4)@Wo_(3-x)S-scheme heterojunction for efficient Co_(2)photoreduction

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第5期92卷 521-533页

作者： Zhijie Zhang Xuesheng Wang junyi Qian Jiayue Xu School of Materials Science and Engineering Shanghai Institute of TechnologyShanghai 201418China

Heterojunction construction,especially S-scheme heterojunction,represents an efficient universal strategy to achieve high-performance photocatalytic *** further performance stimulation of these well-designed heterojunctions,modulating the interfacial internal electric field(IEF)to steer dynamic charge transfer represents a promising ***,we realized the precise regulation of Fermi level(E_(F))of the oxidation semiconductor(mesoporous Wo_(3-x))by tailoring the concentration of oxygen vacancies(V_(o)),maximizing the IEF intensity in Cs_(2)CuBr_(4)@Wo_(3-x)(CCB@Wo_(3-x))S-scheme *** augmented IEF affords a robust driving force for directional electron delivery,leading to boosted charge ***,the developed CCB@Wo_(3-x)S-scheme heterojunction demonstrated outstanding photocatalytic Co_(2)reduction performance,with the electron consumption rate(Relectron)up to 390.34μmol g^(-1)h^(-1),which is 3.28 folds higher than that of pure *** in-depth analysis of the S-scheme electron transfer mode was presented via theoretical investigations,electron spin resonance(ESR),photo-irradiated Kelvin probe force microscopy(KPFM),and in-situ X-ray photoelectron spectroscopy(XPS).Finally,the Co_(2)photoconversion route was explored in detail using in-situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFtS)and DFt theoretical calculations.

关键词： Cs_(2)CuBr_(4) Wo_(3-x) oxygen vacancy S-scheme heterojunction Internal electricfield

New dating indicates intermittent human occupation of the Nwya Devu Paleolithic site on the high-altitude central tibetan Plateau during the past 45,000 years

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第2期67卷 531-551页

作者： junyi gE Xiaoling ZHAng Shejiang WAng Linhui LI wei HE Yingshuai JIN Peiqi ZhAng Bing XU Cheng.ong DEng John WoLSEN Zhengtang g.o Xing g.o Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of SciencesBeijing 100044China University of the Chinese Academy of Sciences Beijing 100049China tibetan Cultural Relics Conservation Institute Lhasa 850000China Key Laboratory of Cenozoic g.ology and Environment Institute of Geology and GeophysicsChinese Academy of Sciences.Beijing 100029China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China School of Anthropology University of ArizonaTucson85721USA

the timing and mechanisms of the human occupation of the demanding high-altitude tibetan Plateau environment are of great ***,we report on our reinvestigations and dating.of the Nwya Devu site,located nearly 4600 meters above sea level on the central tibetan Plateau.A new microblade techno-complex was identified on a lower lake shore at this site,distinct from the previously reported blade tool *** two lithic assemblages were dated to 45.6±2.6 and10.3±0.5 ka using.optically stimulated luminescence and accelerator mass spectrometry^(14)C *** represent,respectively,the earliest known Paleolithic and microlithic sites on the interior tibetan Plateau,indicating multiple occupation episodes of hunter-gatherers during the past 45 *** studies reveal that relatively stable depositional conditions and a paleoenvironment characterized by a comparatively warm climate facilitated these multiple occupations at Nwya *** contemporaneous occurrence of the Upper Paleolithic blade technology on the tibetan Plateau and most of Eurasia between 50 and 40 ka indicates rapid,large-scale dispersals of humans that profoundly affected human demography on a large *** new archaeological evidence and previously reported genetic data,we conclude that the tibetan Plateau provided a relatively stable habitat for Upper Paleolithic hunter-gatherers,which may have contributed to the complex and multiple-origin gene pool of present-day tibetans.

关键词： tibetan Plateau Paleolithic Nwya Devu High-altitude adaptation Microblade industry Early Upper Paleolithic oSLdating AMS^(14)C dating