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Telomere-to-telomere and gap-free reference genome assembly of the kiwifruit Actinidia chinensis

Horticulture Research 2023年第2期10卷 134-146页

作者： junyang Yue Qinyao Chen Yingzhen Wang Lei zhang Chen Ye Xu Wang Shuo Cao Yunzhi Lin Wei Huang He Xian Hongyan Qin Yanli Wang Sijia zhang Ying Wu Songhu Wang Yi Yue Yongsheng Liu School of Horticulture Anhui Agricultural UniversityHefeiAnhui 230036China Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural SciencesShenzhenGuangdong 518124China Institute of Fruit and Tea Hubei Academy of Agricultural SciencesWuhanHubei 430064China School of Information and Computer Anhui Agricultural UniversityHefeiAnhui 230036China Ministry of Education Key Laboratory for Bio-resource and Eco-environment College of Life ScienceState Key Laboratory of Hydraulic and Mountain River EngineeringSichuan UniversityChengduSichuan 610064China Department of Bioinformatics Anhui Double Helix Gene Technology CorporationHefeiAnhui 230022China Comprehensive Testing Ground Xinjiang Academy of Agricultural SciencesUrumqiXinjiang 830012China Institute of Special Animal and Plant Sciences Chinese Academy of Agricultural SciencesChangchunJilin 130112China

Kiwifruit is an economically and nutritionally important fruit crop with extremely high contents of vitamin ***,the previously released versions of kiwifruit genomes all have a mass of unanchored or missing ***,we report a highly continuous and completely gap-free reference genome of Actinidia chinensis cv.‘Hongyang’,named Hongyang v4.0,which is the first to achieve two de novo haploid-resolved haplotypes,HY4P and ***4P and HY4A have a total length of 606.1 and 599.6 Mb,respectively,with almost the entire telomeres and centromeres assembled in each *** comparison with Hongyang v3.0,the integrity and contiguity of Hongyang v4.0 is markedly improved by filling all unclosed gaps and correcting some misoriented regions,resulting in∼38.6–39.5 Mb extra sequences,which might affect 4263 and 4244 protein-coding genes in HY4P and HY4A,***,our gap-free genome assembly provides the first clue for inspecting the structure and function of ***,centromeric regions are characterized by higher-order repeats that mainly consist of a 153-bp conserved centromere-specific monomer(Ach-CEN153)with different copy numbers among *** enrichment analysis of the genes located within centromeric regions demonstrates that chromosome centromeres may not only play physical roles for linking a pair of sister chromatids,but also have genetic features for participation in the regulation of cell *** availability of the telomere-to-telomere and gap-free Hongyang v4.0 reference genome lays a solid foundation not only for illustrating genome structure and functional genomics studies but also for facilitating kiwifruit breeding and improvement.

关键词： breeding linking assembly

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Accessing Alignments of Ontologies via IoT Based on SKOS Data Model

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China Communications 2017年第6期14卷 137-155页

作者： Xiulei Liu Xia Hou junyang Yu Ying Gao Yue zhang Yingying zhang Beijing Key Laboratory of Internet Culture and Digital Dissemination Research Beijing Information Science and Technology University State key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications Software School Henan Univesity

Many ontologies are provided to representing semantic sensors ***,heterogeneity exists in different sensors which makes some service operators of Internet of Thing(IoT) difficult(such as such as semantic inferring,non-linear inverted index establishing,service composing) .There is a great deal of research about sensor ontology alignment dealing with the heterogeneity between the different sensor ontologies,but fewer solutions focus on exploiting syntaxes in a sensor ontology and the pattern of accessing *** solution infers alignments by extending structural subsumption algorithms to analyze syntaxes in a sensor ontology,and then combines the alignments with the SKOS model to construct the integration sensor ontology,which can be accessed via the *** experiments show that the integration senor ontology in the SKOS model can be utilized via the IoT service,and the accuracy of our prototype,in average,is higher than others over the four real ontologies.

关键词：物联网本体数据模型集成传感器路线服务组合语义推理倒排索引

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The Control of Intramolecular Through-Bond and Through-Space Coupling in Single-Molecule Junctions

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CCS Chemistry 2022年第2期4卷 713-721页

作者： Zhibing Tan Wenlin Jiang Chun Tang Li-Chuan Chen Liangliang Chen junyang Liu Zitong Liu Hao-Li zhang Deqing zhang Wenjing Hong State Key Laboratory of Physical Chemistry of Solid Surfaces iChEMCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005 Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsCAS Center of Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190 State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000

Electronic coupling between individual building blocks plays an essential role in charge transport through molecular materials and ***,the investigation of the transmission mechanism in charge transport via intramolecular coupling remains ***,we demonstrate the transition of the intramolecular through-bond and through-space coupling in a single-molecule junction with a family of diketopyrrolopyrrole(DPP)derivative by varying intramolecular donor–acceptor(D–A)*** transition is accomplished by regulating D–A interactions by inserting different aromatic rings inside,leading to two orders of magnitude difference of the single-molecule *** flicker noise analysis demonstrates that the conductance difference arises from the control of the contribution between through-bond and through-space *** findings are further supported by the calculation that the intramolecular coupling among molecular building blocks correlates with the D–A interaction,providing a promising way to regulate the contribution between through-bond and through-space coupling in the charge transport through molecular materials and devices.

关键词： intramolecular coupling single-molecule junctions D-A interaction through-bond throughspace

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Influence of depth-thickness ratio of mining on the stability of a bedding slope with its sliding surface in concave deformation

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International Journal of Mining Science and Technology 2016年第6期26卷 1117-1123页

作者： zhang Yuning Tang Jianxin Li Guodong Teng junyang State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing University

In order to study the influence of depth-thickness ratio on bedding slope stability, whose sliding surface is flexural concave in shape under mining conditions, this paper aims to study the characteristics of deformation and damage of bedding sliding with depth-thickness ratios of 200:1, 150:1, 120:1, 100:1 and 50:1by adopting numerical simulation analysis software combined with laboratory-made ‘‘under the influence of mining variable sliding surface slope similar simulation test bed", and to propose identification methods for slope stability under the influence of mining. The results show that mining activities under the slope reduce slope stability. With a decrease in the mining depth ratio, the influence of mining on the slope increases gradually, and the damage to the slope gradually expands, the stability of the slope gradually reduces, fracture occurs on the slope toe and the central fissure gradually develops to the surface,and reaches slide threshold when the depth-thickness ratio is 50:1.

关键词：边坡稳定性滑动面厚度比采动模拟分析软件开采条件模拟试验台破坏特征

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水库洪水预报-调度-演进一体化模型研究及应用

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水利信息化 2024年第1期 89-94页

作者：张文文徐军杨温州市泽雅水库管理站浙江温州325023 杭州华辰电力控制工程有限公司浙江杭州311100

我国东南沿海地区受梅汛和台风暴雨影响,洪水灾害频发。水库作为重要的防洪工程措施,精准预报、有效调度对于防御洪水及降低洪水风险具有重要意义。针对东南沿海地区水库下游防洪风险问题,以温州市泽雅水库为研究对象,采用三水源新安江... 详细信息

我国东南沿海地区受梅汛和台风暴雨影响,洪水灾害频发。水库作为重要的防洪工程措施,精准预报、有效调度对于防御洪水及降低洪水风险具有重要意义。针对东南沿海地区水库下游防洪风险问题,以温州市泽雅水库为研究对象,采用三水源新安江模型、马斯京根河道演算、水库调度模型、一/二维水动力串联耦合模型,构建水库预报-调度-演进一体化模型。建成的一体化模型集成接入泽雅智慧水库平台,推动水库防洪业务数字化转型。历史洪水模拟结果表明:泽雅水库洪水预报、防洪调度及下游洪水演进模型能够满足水库保护下游城镇安全的要求,有助于提高水库洪水预报调度科学化、数字化、精细化水平。

关键词：洪水预报防洪调度水文模型水动力模型泽雅水库

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海上风电用环保型断路器绝缘特性分析及优化设计

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河南科学 2024年第7期42卷 960-967页

作者：柴子元王文博魏建巍柴影辉朱秋楠崔军阳张路阳平高集团有限公司河南平顶山467000 河南平芝高压开关有限公司河南平顶山467013

环保型断路器的应用是实现高压开关设备绿色发展的必然途径之一.为探究72.5 kV海上风电用环保型断路器的绝缘特性,建立了其数值仿真模型,研究了相应位置的电场分布及影响因素,并根据计算结果开展了内部绝缘结构优化设计.研究表明:当端... 详细信息

环保型断路器的应用是实现高压开关设备绿色发展的必然途径之一.为探究72.5 kV海上风电用环保型断路器的绝缘特性,建立了其数值仿真模型,研究了相应位置的电场分布及影响因素,并根据计算结果开展了内部绝缘结构优化设计.研究表明:当端屏蔽罩圆角半径为28mm、金属化瓷壳高度为145mm、中间屏蔽罩长度43 mm时,真空灭弧室绝缘特性最优;雷电冲击电压下断路器最大电场强度为20.12 kV/mm,结构优化后电场强度均低于16.80kV/mm,并开展了绝缘试验验证,均顺利通过试验,该研究可为断路器样机结构设计提供支撑.

关键词：环保型断路器绝缘特性电场分析优化设计

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Highly insulating alkane rings with destructive σ-interference

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Science China Chemistry 2022年第9期65卷 1822-1828页

作者： Jingyao Ye Alaa Al-Jobory Qian-Chong zhang Wenqiang Cao Abdullah Alshehab Kai Qu Turki Alotaibi Hang Chen junyang Liu Ali K.Ismael Zhong-Ning Chen Colin J.Lambert Wenjing Hong State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Department of Physics Lancaster UniversityLancaster LA14YBUK State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China Department of Physics College of Education for Pure ScienceTikrit UniversityTikritIraq Department of Physics College of ScienceUniversity of AnbarAnbarIraq School of Physical Science and Technology Shanghai Tech UniversityShanghai 201210China Department of Physics College of ScienceKing Faisal UniversityAlAhsaSaudi Arabia Department of Physics College of ScienceJouf UniversitySkakaSaudi Arabia

Destructive quantum interference(DQI)provides a unique approach to controlling the leakage current in the OFF state of molecular ***,the DQI in π-conjugated molecular building blocks cannot exhibit ultralow conductance due to the existence of covalently bonded σ-transport ***,suppressing the σ-contribution via σ-DQI is essential for the fabrication of molecular junctions with high insulation and effective modulation of conductance in single-molecule ***,we demonstrate the existence of σ-DQI even in a simple series of C_(m)C_(n) ring molecules,with parallel chains of m and n alkyl units(where m,n=6,8 or 10),by measuring their electrical conductance and Seebeck ***,the conductance of the symmetric C_(n)C_(n) rings is lower than that of the corresponding single chains(C_(n)),which is in contrast to the conductance superposition law in multi-channeled *** theoretical calculations reveal that the gauche conformation in a shorter chain fixed by another chain leads to the decreased conductance in alkyl rings,which originates from the phase-coherent tunneling and DQI in σ-conjugated *** finding suggests that through appropriate conformation locking by cyclization,the covalent alkane system can exhibit DQI,which offers strategies for future designs of molecular electronic devices and materials.

关键词： destructiveσ-interference charge transport single-molecule electronics insulating material alkane ring

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A review of data mining technologies in building energy systems:Load prediction,pattern identification,fault detection and diagnosis

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能源与人工环境(英文) 2020年第2期1卷 149-164页

作者： Yang Zhao Chaobo zhang Yiwen zhang Zihao Wang junyang Li Institute of Refrigeration and Cryogenics Zhejiang UniversityHangzhouChina

With the advent of the era of big data,buildings have become not only energy-intensive but also *** mining technologies have been widely utilized to release the values of massive amounts of building operation data with an aim of improving the operation performance of building energy *** paper aims at making a comprehensive literature review of the applications of data mining technologies in this *** general,data mining technologies can be classified into two categories,i.e.,supervised data mining technologies and unsupervised data mining *** this field,supervised data mining technologies are usually utilized for building energy load prediction and fault detection/*** unsupervised data mining technologies are usually utilized for building operation pattern identification and fault detection/*** discussions are made about the strengths and shortcomings of the data mining-based *** on this review,suggestions for future researches are proposed towards effective and efficient data mining solutions for building energy systems.

关键词： Supervised data mining Unsupervised data mining Big data Building energy efficiency Building energy systems

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Data-Driven Discovery of Stochastic Differential Equations

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Engineering 2022年第10期17卷 244-252页

作者： Yasen Wang Huazhen Fang junyang Jin Guijun Ma Xin He Xing Dai Zuogong Yue Cheng Cheng Hai-Tao zhang Donglin Pu Dongrui Wu Ye Yuan Jorge Gonçalves Jürgen Kurths Han Ding School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China Department of Mechanical Engineering University of KansasLawrenceKS 66045USA HUST-Wuxi Research Institute Wuxi 214174China Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and AutomationHuazhong University of Science and TechnologyWuhan 430074China Department of Plant Sciences University of CambridgeCambridge CB23EAUK Luxembourg Centre for Systems Biomedicine University of LuxembourgBelvaux 4367Luxembourg Department of Physics Humboldt University of BerlinBerlin 12489Germany Department of Complexity Science Potsdam Institute for Climate Impact ResearchPotsdam 14473Germany

Stochastic differential equations(SDEs)are mathematical models that are widely used to describe complex processes or phenomena perturbed by random noise from different *** identification of SDEs governing a system is often a challenge because of the inherent strong stochasticity of data and the complexity of the system’s *** practical utility of existing parametric approaches for identifying SDEs is usually limited by insufficient data *** study presents a novel framework for identifying SDEs by leveraging the sparse Bayesian learning(SBL)technique to search for a parsimonious,yet physically necessary representation from the space of candidate basis *** importantly,we use the analytical tractability of SBL to develop an efficient way to formulate the linear regression problem for the discovery of SDEs that requires considerably less time-series *** effectiveness of the proposed framework is demonstrated using real data on stock and oil prices,bearing variation,and wind speed,as well as simulated data on well-known stochastic dynamical systems,including the generalized Wiener process and Langevin *** framework aims to assist specialists in extracting stochastic mathematical models from random phenomena in the natural sciences,economics,and engineering fields for analysis,prediction,and decision making.

关键词： Data-driven method System identification Sparse Bayesian learning Stochastic differential equations Random phenomena

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HIV-1 DNA levels in peripheral blood mononuclear cells of patients with HIV-related non-Hodgkin’s lymphoma

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Chinese Medical Journal 2023年第22期136卷 2741-2743页

作者： Zhenyan Wang Jingna Xun Zichen Song Yinzhong Shen Li Liu Jun Chen Tangkai Qi Jianjun Sun Wei Song Yang Tang Shuibao Xu junyang Yang Bihe Zhao Renfang zhang Department of Infection and Immunity Shanghai Public Health Clinical CenterFudan UniversityShanghai 201508China

To the Editor:Human immunodeficiency virus(HIV)patients have an increased risk of non-Hodgkin’s lymphoma(NHL),even in the era of antiretroviral therapy(ART).[1]The specific mechanisms of HIVrelated NHL(HIV-NHL)remain *** is currently thought that HIV causes lymphoma primarily through chronic immune activation and an increased risk of infection with *** addition,HIV may have some other mechanisms that directly contribute to the occurrence of lymphoma.[2]Even with sustained ART,HIV-DNA remains in infected cells,creating a persistent reservoir of HIV *** is not known whether HIV reservoirs are involved in the development of *** the present study,we detected HIV-1 DNA levels in peripheral blood mononuclear cells(PBMCs)and plasma inflammatory cytokines levels in HIV-NHL,and then evaluated their effects on HIV-NHL development and prognosis.

关键词： lymphoma patients sustained

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