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Chinese Journal of Chemical Engineering 2021年第11期34卷 96-102页

作者： juntian xiao Qian Sun Liying Liu Zhongwei Ding Beijing Key Laboratory of Membrane Science and Technology College of Chemical EngineeringBeijing University of Chemical TechnologyBeijing 100029China Beijing Advanced Innovation Center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic CompositesBeijing University of Chemical TechnologyBeijing 100029China

In the process of membrane absorption,spontaneous wetting of hydrophobic microporous membrane causes membrane modification and increases membrane phase mass transfer resistance,which have attracted wide ***,due to the limitations of previous testing methods,the study of the spontaneous membrane wetting process is ***,we present a method for monitoring spontaneous membrane wetting by measuring its alternating current(AC)*** impedance tests of the PVDF flat membranes and hollow fiber membranes were conducted in a two-electrode *** results of equivalent circuit fitting indicate that the impedance value of the unwetted membrane is about 1.02×10^(10)Ω,which is close to the theoretical value of 1.4×10^(10)Ω,and this method can quantify the electrochemical impedance value of membranes with different degrees of spontaneous *** addition,a method of impedance test for real-time monitoring of spontaneous wetting was *** the experiment,the timeliness and continuity of this method are confirmed with exact judgment under different *** future work,the impedance data will be used to build model to predict the percentage of membrane wetting degree.

关键词： Alternating current impedance Spontaneous membrane wetting Hydrophobic membrane Dynamic monitoring

PVDF膜接触器吸收二氧化碳过程中延缓膜润湿的研究

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膜科学与技术 2019年第5期39卷 73-80页

作者：王利祥丁忠伟刘丽英肖钧天北京化工大学化学工程学院

采用二乙醇胺水溶液为吸收剂于聚偏氟乙烯(PVDF)中空纤维膜组件中吸收CO2,研究了膜吸收过程中延缓膜润湿的方法.实验分别考察了气相压力的加压方式、加压时长以及液相添加无机盐对膜浸润的影响,并对膜浸润进行了理论分析.实验结果表明,... 详细信息

采用二乙醇胺水溶液为吸收剂于聚偏氟乙烯(PVDF)中空纤维膜组件中吸收CO2,研究了膜吸收过程中延缓膜润湿的方法.实验分别考察了气相压力的加压方式、加压时长以及液相添加无机盐对膜浸润的影响,并对膜浸润进行了理论分析.实验结果表明,随着气相间歇加压的压力增大,膜浸润百分数最多下降33%,气相间歇加压存在最优的加压时长和合理的加压程序.保持气相压力持续为高压态,并不能有效地延缓膜润湿.通过向吸收剂中添加无机盐成分,可以减少自发浸润的进行,在吸收过程中膜浸润率下降16.7%.

关键词：疏水性中空纤维膜膜润湿延缓膜润湿

Survival of patients with stomach cancer in Changle city of China

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World Journal of Gastroenterology 2004年第11期10卷 1543-1546页

作者： juntian xiao-DongWang Zhen-ChunChen DepartmentofEpidemiologyandHealthStatistics FujianMedicalUniversityFuzhou350004FujianProvinceChina CollegeofMathematicsandComputerscience FuzhouUniversityFuzhou350002FuiianProvinceChina FujianCancerHospital Fuzhou350014FujianProvinceChina

AIM: The survival rate of patients with stomach cancer is used to evaluate the effects of treatments. The short- and mid-term survival of patients on the present level of treatments can be described by calculating 1- to 5-year survival rates. The aims of this study were to document patterns of survival after treatments for stomach cancer in Changle city and analyze whether the stage of cancer and the way of treatment impacted on survival of patients or not. METHODS: A total number of 745 patients with stomach cancer reported in the Changle Cancer Registry from 1993 to 1998 were investigated with respect to the disease condition, the way of treatment and survival time. 1- to 5- year survival rates were estimated by using life-table method. RESULTS: The 1- to 5-year survival rates in the patients with stomach cancer in Changle city were 54.23%, 41.77%, 37.95%, 33.98% and 30.47%, respectively. The 1- to 5-year survival rates in stageIor II group were 3, 6.1, 7.4, 8.9 and 9.8 times as high as those in stage III or IV group, respectively. The 1- to 5-year survival rates in operation group were 3.5, 8.7, 11.2, 11.7 and 19 times as high as those in no operation group, respectively. For the patients with stage III or IV stomach cancer the 1-year survival rate in operation group was 3 times as high as that in no operation group and 2- year survival rate in operation group was 11.9 times as high as that in no operation group. For the patients wibh stage III or 1V stomach cancer, the differences of the survival rates average survival times between total gastrectomy and partial gastrectomy were not significant and the median survival times in these 2 groups were 8 mo and 9 mo, respectively. CONCLUSION: Mid-term survival rates of patients with stomach cancer in Changle city are low. Stage of cancer is an important factor influencing survival of patients with stomach cancer. Surgery is an effective treatment for the patients with stage IV cancer and can raise short- and mid-term

关键词：胃癌肿瘤中国长乐市流行病

Interpretation of breast cancer screening guideline for Chinese women

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Cancer Biology & Medicine 2019年第4期16卷 825-835页

作者： Yubei Huang Zhongsheng Tong Kexin Chen Ying Wang Peifang Liu Lin Gu juntian Liu Jinpu Yu Fengju Song Wenhua Zhao Yehui Shi Hui Li Huaiyuan xiao Xishan Hao Department of Epidemiology and Statistics Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Medicine Department of Breast Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China China Anti-Cancer Association Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Department of Breast Imaging Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China The 2nd Surgery Department of Breast Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Cancer Prevention Center Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Cancer Molecular Diagnostics Core Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Department of Gastrointestinal Cancer Biology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Department of Research and Education Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China

Breast cancer is the most common malignant tumor in Chinese *** screening is the best way to improve the rates of early diagnosis and survival of breast cancer *** peak onset age for breast cancer in Chinese women is considerably younger than those in European and American *** is imperative to develop breast cancer screening guideline that is suitable for Chinese *** summarizing the current evidence on breast cancer screening in Chinese women,and referring to the latest guidelines and consensus on breast cancer screening in Europe,the United States,and East Asia,the China Anti-Cancer Association and National Clinical Research Center for Cancer(Tianjin Medical University Cancer Institute and Hospital)have formulated population-based guideline for breast cancer screening in Chinese *** guideline provides recommendations on breast cancer screening for Chinese women at average or high risk of breast cancer according to the following three aspects:age of screening,screening methods,and screening *** article provides more detailed information to support the recommendations in this guideline and to provide more direction for current breast cancer screening practices in China.

关键词： Breast cancer screening ultrasound mammography guideline

不同自动铺丝工艺参数对T800级碳纤维/环氧复合材料孔隙率的影响研究

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航空制造技术 2023年第3期66卷 114-118,124页

作者：刘钧天陈萍闫超肖鹏中国商飞上海飞机制造有限公司上海200436

采用T800级碳纤维/环氧树脂单向带铺丝预浸料,使用自动铺丝工艺制备不同厚度的试验层板,探究固化压力、层板厚度及尺寸、自动铺丝压紧力等各项参数对孔隙率及孔隙分布的影响,采用超声C扫描表征复合材料层板孔隙率区间。研究表明,当固化... 详细信息

采用T800级碳纤维/环氧树脂单向带铺丝预浸料,使用自动铺丝工艺制备不同厚度的试验层板,探究固化压力、层板厚度及尺寸、自动铺丝压紧力等各项参数对孔隙率及孔隙分布的影响,采用超声C扫描表征复合材料层板孔隙率区间。研究表明,当固化压力降至某临界点后,孔隙率呈现先快速增加又逐渐减慢增加的趋势;厚铺层的层板的孔隙率高于较薄铺层的层板,靠近中间及底部铺层位置的孔隙较多;尺寸较大的层板,高孔隙率的区域相对集中分布在靠近层板中间的位置,且孔隙率区间较大;固化压力较小时,采用小压紧力铺丝的层板会形成更高的孔隙率;对于大型复杂的复材结构件来说,不同的铺丝工艺参数对孔隙率的影响也具有上述趋势。

关键词：复合材料孔隙率固化压力自动铺丝超声检测

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非水介质中曲克芦丁乙烯酯的酶促合成

有机化学 2010年第4期30卷 551-557页

作者：肖咏梅栗俊田毛璞赵贞林贤福河南工业大学化学化工学院郑州450001 浙江大学化学系杭州310027

在非水介质中,选择性催化曲克芦丁羟乙基上的伯羟基发生酯交换反应,合成一系列曲克芦丁乙烯酯.同时考察了酶源、酶量、反应介质、酰化试剂链长、溶剂含水量、反应时间等因素对曲克芦丁酶促酯交换反应区域选择性的影响.结果表明:以吡啶... 详细信息

在非水介质中,选择性催化曲克芦丁羟乙基上的伯羟基发生酯交换反应,合成一系列曲克芦丁乙烯酯.同时考察了酶源、酶量、反应介质、酰化试剂链长、溶剂含水量、反应时间等因素对曲克芦丁酶促酯交换反应区域选择性的影响.结果表明:以吡啶为溶剂,其含水量<1%时,枯草杆菌碱性蛋白酶催化活性最高,随着酰基供体碳链的减少,产率增大,且反应达平衡的时间缩短.

关键词：曲克芦丁酶促合成区域选择性酯交换反应

窦口鼻道复合体CT影像解剖与慢性鼻窦炎的相关性研究

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第二军医大学学报 1999年第7期20卷 480-482页

作者：郎军添萧璧君范静平第二军医大学长征医院耳鼻咽喉科

目的：研究窦口鼻道复合体（ｏｓｔｉｏｍｅａｔａｌｃｏｍｐｌｅｘ，ＯＭＣ）的ＣＴ影像解剖与慢性鼻窦炎的相关性，为ＯＭＣ的研究提供影像解剖学的新思路。方法：对６７例头颅冠状ＣＴ薄层扫描片进行观测，包括：中鼻道宽度，筛漏斗... 详细信息

目的：研究窦口鼻道复合体（ｏｓｔｉｏｍｅａｔａｌｃｏｍｐｌｅｘ，ＯＭＣ）的ＣＴ影像解剖与慢性鼻窦炎的相关性，为ＯＭＣ的研究提供影像解剖学的新思路。方法：对６７例头颅冠状ＣＴ薄层扫描片进行观测，包括：中鼻道宽度，筛漏斗长度、宽度，钩突厚度、内倾角度，筛泡、鼻丘的内径，并对测量结果与鼻窦炎积分进行相关性分析。结果：６７例（１３４侧）中钩突头端的附着部位有３种类型：筛顶型（２３．１３％）、纸样板型（５６．７２％）和中鼻甲型（２０．１５％），这３种类型的比例在鼻窦炎组与非鼻窦炎组有较大差异（Ｐ＜０．０１）。鼻窦炎组与非鼻窦炎组筛漏斗长度有显著差异（Ｐ＜０．０１）。筛漏斗长度及钩突角度与鼻窦炎积分之间有显著相关性。结论：ＯＭＣ解剖因素（包括筛漏斗及钩突的发育等）与慢性鼻窦炎发病有密切关系。

关键词：窦口鼻道复合体鼻窦炎影像解剖慢性 CT

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2019年FDA批准新药中孤儿药分析

药学研究 2020年第9期39卷 550-553页

作者：周冲刘军田肖杰山东省食品药品审评认证中心山东济南250014

本文对2019年美国食品药品监督管理局(FDA)批准的新药进行了统计分析,通过对新药和孤儿药基本情况、获得优先审批权、临床病例数等进行对比分析,详细了解美国食品药品监督管理局对新药孤儿药的审批优惠政策,提出我国制定孤儿药相关政策... 详细信息

本文对2019年美国食品药品监督管理局(FDA)批准的新药进行了统计分析,通过对新药和孤儿药基本情况、获得优先审批权、临床病例数等进行对比分析,详细了解美国食品药品监督管理局对新药孤儿药的审批优惠政策,提出我国制定孤儿药相关政策的建议,为我国相关政策的制定和企业相关产品研发工作提供思路。

关键词：美国食品药品监督管理局批准新药孤儿药优先审批权病例数

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二维三七桂利嗪胶囊对急性脑缺血的保护作用

西安交通大学学报（医学版） 2006年第2期27卷 137-139,146页

作者：肖湘华邓秀玲王燕刘俊田王竹筠西安交通大学医学院药理学系陕西西安710061 丽珠集团丽宝生物化学制药有限公司广东珠海519020

目的观察二维三七桂利嗪胶囊对于急性脑缺血的影响。方法ICR小鼠分别用420 mg/kg、210 mg/kg、105 mg/kg的二维三七桂利嗪胶囊灌胃10 d,观察断头后小鼠的喘息时间;SD大鼠分别用292 mg/kg、146 mg/kg、73 mg/kg的二维三七桂利嗪胶囊灌胃1... 详细信息

目的观察二维三七桂利嗪胶囊对于急性脑缺血的影响。方法ICR小鼠分别用420 mg/kg、210 mg/kg、105 mg/kg的二维三七桂利嗪胶囊灌胃10 d,观察断头后小鼠的喘息时间;SD大鼠分别用292 mg/kg、146 mg/kg、73 mg/kg的二维三七桂利嗪胶囊灌胃10 d,线栓法制备大鼠大脑中动脉栓塞模型,然后进行神经行为指标评分、脑梗死范围测定和病理学观察。结果二维三七桂利嗪胶囊各剂量组均能延长小鼠断头后的喘息时间,缩小局灶性脑缺血大鼠脑梗死范围,改善神经症状,减轻光镜下脑组织缺血性损伤。结论二维三七桂利嗪胶囊对急性脑缺血损伤具有保护作用。

关键词：二维三七桂利嗪胶囊急性脑缺血神经保护作用

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筛动脉筛窦段的鼻内窥镜手术相关解剖

解剖学杂志 1999年第3期22卷 222-226页

作者：郎军添萧璧君范静平党瑞山纪荣明第二军医大学附属长征医院耳鼻喉科上海200003 第二军医大学解剖学教研室

目的 :研究筛动脉在筛窦内的走行特点 ,为减少鼻内窥镜手术并发症提供解剖指导。方法 :通过 30具湿性成人尸头 (男 19,女 11)的解剖 ,观测了筛动脉在筛窦段的走行部位、方向、骨管厚度及其与筛窦气房的关系。结果 :( 1)筛前动脉与中鼻... 详细信息

目的 :研究筛动脉在筛窦内的走行特点 ,为减少鼻内窥镜手术并发症提供解剖指导。方法 :通过 30具湿性成人尸头 (男 19,女 11)的解剖 ,观测了筛动脉在筛窦段的走行部位、方向、骨管厚度及其与筛窦气房的关系。结果 :( 1)筛前动脉与中鼻甲基板的位置关系密切 ,多走行于中鼻甲基板之前的紧邻筛房顶 ( 66.6% )及中甲基板顶 ( 2 6.7% ) ;筛后动脉则以位于最后筛房顶最为多见 ( 64.9% ) ;( 2 )筛前、后动脉骨管的下壁明显薄于上壁 ( P<0 .0 1) ;( 3)部分筛前、后动脉骨管的下壁存在部分或全部的缺损 ;( 4 )过度气化的额窦或前筛气房的后 (下 )壁可取代前颅底成为筛动脉骨管的顶壁。结论 :上述解剖特点对于鼻内窥镜手术中避免筛动脉的损伤。

关键词：筛前动脉筛后动脉筛窦鼻内窥镜手术解剖