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Effects of tourmaline on nitrogen removal performance and biofilm structures in the sequencing batch biofilm reactor

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Journal of Environmental Sciences 2018年第5期30卷 127-135页

作者： Chong Tan Haoran Xu Di Cui Jinlong Zuo junsheng Li Yubin Ji Shan Qiu lin Yao Ying Chen Yingjie Liu Research Center on Life Sciences and Environmental Sciences Harbin University of Commerce School of Municipal and Environmental Engineering Harbin Institute of Technology Key Laboratory of Molecular and Cytogenetics and Genetic Breeding of Heilongjiang Province Harbin Normal University

The effects of tourmaline on nitrogen removal performance and biofilm structures were comparatively investigated in two identical laboratory-scale sequencing batch biofilm reactors（SBBRs）（denoted SBBR1 and SBBR2） at different nitrogen loading rates（NLRs） varying from（0.24 ± 0.01） to（1.26 ± 0.02） g N/（L·day）. SBBR1 was operated in parallel with SBBR2, but SBBR1 was filled with polyurethane foam loaded tourmaline（TPU） carriers and another（SBBR2） filled with polyurethane foam（PU） carriers. Results obtained from this study showed that the excellent and stable performance of SBBR1 was obtained. Ammonia nitrogen removal and total nitrogen removal were higher in SBBR1 than that in SBBR2 with increase of NLR. At an NLR of（0.24 ± 0.01） g N/（L·day）, the majority of the spherical and elliptical bacteria were surrounded by the extracellular polymeric substance（EPS） and bacillus or filamentous bacteria in two SBBRs biofilms. When NLR increased to（1.26 ± 0.02） g N/（L·day）, the clusters were more obvious in the SBBR1 biofilm than that in the SBBR2 biofilm. Bacteria in SBBR1 were inclined to synthesis more EPS, and the formed EPS could protect the bacteria from free ammonia（FA） under extreme condition NLR（1.26 ± 0.02） g N/（L·day）. The results of polymerase chain reaction-denaturing gradient gel electrophoresis analysis showed that the microbial community similarity in SBBR2 decreased more obviously than that in SBBR1 with the increase of NLR, which the microbial community in SBBR1 was relatively stable.

关键词： tourmaline Nitrogen removal performance Biofilm structures Population dynamics Sequencing batch biofilmreactor (SBBR)

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Mainchain conformation ordering self-assembly tailored room temperature phosphorescence emission

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Science China Chemistry 2025年第01期 329-336页

作者： Yuzhu Li Yumeng Gao Feng Tian Yu Wang Yuan Yao Shaoliang lin Xiang Ma Binbin Xu Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences Key Laboratory for Advance Materials and Feringa Noble Prize Scientist Joint Research Centre Frontiers Science for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular Engineering East China University of Science & Technology

Developing organic room-temperature phosphorescence （RTP） materials with a wide range of tunable-emission is significant in expanding the applications of RTP ***,we rationally designed amphiphilic alternating copolymers poly(1,2-bis（4-alkoxyphenyl）ethane-1,2-dione-alt-（ethylene glycol）x)(P（Bz-alt-EGx）) that combined the advantage of alternating benzil and EGxskeleton,and tunable mainchain *** a mainchain conformation ordering assembly （COA） process,P（Bz-alt-EGx） self-assembled into well-defined platelets,and such assemblies emitted blue RTP at ca.425 nm due to the ordered folded-chain conformation and confined *** contrast,traditional self-assembly （TA） of P（Bz-alt-EGx） obtained less ordered aggregates,such as asymmetric worms,vesicles,and rod-like *** resultant less ordered aggregates exhibited yellow-green RTP at ca.550 *** wide-tuning RTP emission in solution （between blue and yellow-green,over125 nm） is realized using the P（Bz-alt-EGx） alternating copolymers under the treatment of different self-assembly *** study uncovers a new strategy to tailor the RTP emission through different self-assembly pathways and holds great promise for the fabrication of advanced optical materials.

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新中国成立以来我国纪检监察体制的演进与启示

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学习论坛 2025年第1期 56-63页

作者：林怀艺华侨大学福建泉州362021

中国共产党历来重视发挥纪检监察体制的作用。新中国成立后,党及时将纪检监察体制建设提上日程,纪检监察体制经历了社会主义革命和建设时期的曲折发展、改革开放和社会主义现代化建设新时期的改革完善和中国特色社会主义新时代的守正创... 详细信息

中国共产党历来重视发挥纪检监察体制的作用。新中国成立后,党及时将纪检监察体制建设提上日程,纪检监察体制经历了社会主义革命和建设时期的曲折发展、改革开放和社会主义现代化建设新时期的改革完善和中国特色社会主义新时代的守正创新,为党和国家事业的发展贡献了力量。新中国成立以来我国纪检监察体制的演进启示我们,深化党在新征程上对纪检监察体制的改革,必须坚持和发展马克思主义纪检监察理论,必须将加强党的领导和加强党内监督作为主题,必须紧密结合党的自身建设,必须正确处理一系列重要的党内关系,必须依规依纪依法并注重形成合力。

关键词：新中国中国共产党纪检监察体制

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Advances in the Development of Gradient Scaffolds Made of Nano-Micromaterials for Musculoskeletal Tissue Regeneration

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NANO-MICRO LETTERS 2025年第1期17卷 1-46页

作者： Fang, Lei lin, Xiaoqi Xu, Ruian Liu, Lu Zhang, Yu Tian, Feng Li, Jiao Jiao Xue, Jiajia Beijing Univ Chem Technol Beijing Lab Biomed Mat Beijing 100029 Peoples R China Beijing Univ Chem Technol State Key Lab Organ Inorgan Composites Beijing 100029 Peoples R China Univ Technol Sydney Fac Engn & IT Sch Biomed Engn Sydney NSW 2007 Australia

This review highlights the gradient variations in the structural composition of musculoskeletal tissues and comprehensively examines recent progress in the fabrication and application of biomimetic gradient scaffolds for musculoskeletal *** challenges and prospects of gradient scaffolds for clinical application are discussed. The intricate hierarchical structure of musculoskeletal tissues, including bone and interface tissues, necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes. This has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic outcomes. Building on the anatomical characteristics of bone and interfacial tissues, this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues, specifically focusing on methods used to construct compositional and structural gradients within the scaffolds. The latest applications of gradient scaffolds for the regeneration of bone, osteochondral, and tendon-to-bone interfaces are presented. Furthermore, the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed, as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

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NOX4 exacerbates Parkinson's disease pathology by promoting neuronal ferroptosis and neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 2038-2052页

作者： Zhihao lin Changzhou Ying Xiaoli Si Naijia Xue Yi Liu Ran Zheng Ying Chen Jiali Pu Baorong Zhang Department of Neurology The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina

Parkinson's disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra ***,a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation,plays a vital role in the death of dopaminergic ***,the molecular mechanisms underlying ferroptosis in dopaminergic neurons have not yet been completely *** oxidase 4 is related to oxidative stress,however,whether it regulates dopaminergic neuronal ferroptosis remains *** aim of this study was to determine whether NADPH oxidase 4 is involved in dopaminergic neuronal ferroptosis,and if so,by what *** found that the transcriptional regulator activating transcription factor 3 increased NADPH oxidase 4 expression in dopaminergic neurons and astrocytes in an 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced Parkinson's disease *** oxidase 4 inhibition improved the behavioral impairments observed in the Parkinson's disease model animals and reduced the death of dopaminergic ***,NADPH oxidase 4 inhibition reduced lipid peroxidation and iron accumulation in the substantia nigra of the Parkinson's disease model ***,we found that NADPH oxidase 4 interacted with activated protein kinase Cαto prevent ferroptosis of dopaminergic ***,by lowering the astrocytic lipocalin-2 expression,NADPH oxidase 4 inhibition reduced 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced *** findings demonstrate that NADPH oxidase 4 promotes ferroptosis of dopaminergic neurons and neuroinflammation,which contribute to dopaminergic neuron death,suggesting that NADPH oxidase 4 is a possible therapeutic target for Parkinson's disease.

关键词： dopaminergic neuron ferroptosis NADPH oxidase 4(NOX4) neuroinflammation Parkinson's disease

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显微超声技术行牙半切术的临床疗效

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中华口腔医学研究杂志（电子版） 2015年第3期9卷 45-47页

作者：林俊生刘学刘莹谢安琪邓艳芳张晓东刘明月深圳市第六人民医院口腔科 518052

目的探讨应用显微超声技术行牙半切术的临床疗效,为临床进一步推广提供依据。方法选择30例一侧基本完好,一侧病变严重的患牙,随机分为对照组和实验组,每组15颗。对照组行传统的牙半切术,实验组应用显微超声技术行牙半切术,术后1、3年后... 详细信息

目的探讨应用显微超声技术行牙半切术的临床疗效,为临床进一步推广提供依据。方法选择30例一侧基本完好,一侧病变严重的患牙,随机分为对照组和实验组,每组15颗。对照组行传统的牙半切术,实验组应用显微超声技术行牙半切术,术后1、3年后复诊评估其成功率以及边缘性牙龈炎的发生率。采用Pearson Chi-Square检验统计牙半切术的疗效,当频数少于5时则采用Fisher精确概率法,检验水准α=0.05。结果两组术后1年和3年成功率差异无统计学意义(P1=1,P3=1),实验组术后3年边缘性牙龈炎发生率低(P=0.035)。结论显微超声技术行牙半切术可以有效的保存一侧基本完好,一侧病变严重的患牙,可有效降低术后边缘性牙龈炎的发生。

关键词：牙半切术显微根周手术超声技术边缘性牙龈炎

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基于多旋翼无人机的机载激光点云树障隐患识别方法

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电力信息与通信技术 2021年第7期19卷 47-53页

作者：苏华权李国强彭泽武林俊省王丛温柏坚裴求根谢瀚阳陈赟广东电网有限责任公司信息中心广东广州510062 广东电网有限责任公司机巡作业管理中心广东广州510600

传统的架空输电线路树障隐患识别方法速度慢,树障隐患识别过程耗时较长。为了解决这个问题,文章设计了一种基于多旋翼无人机的机载激光点云树障隐患识别方法。以激光雷达点云作为识别技术,构建B/S架构的激光雷达点云数据运算框架体系。... 详细信息

传统的架空输电线路树障隐患识别方法速度慢,树障隐患识别过程耗时较长。为了解决这个问题,文章设计了一种基于多旋翼无人机的机载激光点云树障隐患识别方法。以激光雷达点云作为识别技术,构建B/S架构的激光雷达点云数据运算框架体系。以多旋翼无人机机体为坐标原点,构建巡检空间坐标系,对树障隐患实施跟踪监测。将不同跟踪周期内的无人机位置点作为不同的空间点,对树障隐患位置进行定位。以无人机飞行过程中3个轴向的不确定参数作为设备隐患距离参数,采用嵌入式容积卡尔曼滤波(Embedded Cubature Kalman Filter,ECKF)算法创建一个随机常数值,控制识别过程的计算量,并实现对树障隐患的识别。实验结果表明,该方法的平均识别程度参数约为82.2%,识别精度数值约为0.94,所需的平均识别时间约为5 ms,证明其满足设计预期。

关键词：多旋翼无人机电力巡检树障隐患识别

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Analysis and external validation of a nomogram to predict peritoneal dissemination in gastric cancer

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Chinese Journal of Cancer Research 2020年第2期32卷 197-207页

作者： Xijie Chen Shi Chen Xinyou Wang Runcong Nie Dongwen Chen Jun Xiang Yijia lin Yingbo Chen junsheng Peng Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655China Guangdong Institute of Gastroenterology Guangzhou 510655China departm ent of Gastrointestinal Surgery The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655China Department of Gastric Surgery Sun Yat-sen University Cancer CenterGuangzhou 510060China

Objective:Peritoneal dissemination is difficult to diagnose by conventional imaging *** aimed to construct a nomogram to predict peritoneal dissemination in gastric cancer(GC)***:We retrospectively analyzed 1,112 GC patients in Sun Yat-sen University Cancer Center between2001 and 2010 as the development set and 474 patients from The Sixth Affiliated Hospital,Sun Yat-sen University between 2010 and 2016 as the validation *** clinicopathological variables associated with gastric cancer with peritoneal dissemination(GCPD)were *** used logistic regression analysis to identify independent risk factors for peritoneal ***,we constructed a nomogram for the prediction of GCPD and defined its predictive value with a receiver operating characteristic(ROC)*** validation was performed to validate the applicability of the ***:In total,250 patients were histologically identified as having peritoneal *** regression analysis demonstrated that age,sex,tumor location,tumor size,signet-ring cell carcinoma(SRCC),T stage,N stage and Borrmann classification IV(Borrmann IV)were independent risk factors for peritoneal *** constructed a nomogram consisting of these eight factors to predict GCPD and found an optimistic predictive capability,with a C-index of 0.791,an area under the curve(AUC)of 0.791,and a 95%confidence interval(95%CI)of *** results found in the external validation set were also ***:We constructed a highly sensitive nomogram that can assist clinicians in the early diagnosis of GCPD and serve as a reference for optimizing clinical management strategies.

关键词： Gastric cancer peritoneal dissemination nomogram

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1p36与12q24隐匿性易位致多发畸形胎儿的遗传学分析

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福建医科大学学报 2023年第5期57卷 371-375页

作者：林俊生叶怡虹卢娉霞胡倩叶婷婷陈加弟曹颖平福建医科大学附属协和医院检验科福州350001

目的明确超声异常的多发畸形胎儿的遗传学病因及其父母的细胞遗传学分析。方法家系中的父母及胎儿均行常规核型分析(CCA)、单核苷酸多态性微阵列(SNP)分析,并利用荧光原位杂交(FISH)进行验证。结果胎儿的CCA结果为46,XX,父亲和母亲均未... 详细信息

目的明确超声异常的多发畸形胎儿的遗传学病因及其父母的细胞遗传学分析。方法家系中的父母及胎儿均行常规核型分析(CCA)、单核苷酸多态性微阵列(SNP)分析,并利用荧光原位杂交(FISH)进行验证。结果胎儿的CCA结果为46,XX,父亲和母亲均未见明显异常。SNP结果显示,胎儿存在1p36.33p36.13缺失(15.8 Mb)、12q24.31q24.33重复(10.8 Mb)和Xp22.12重复(506.1 kb);母亲未见异常;父亲存在Xp22.12重复(506.1 kb),但并未有临床疾病表型。FISH分析提示,胎儿ish der(1)t(1;12)(12q+,1q+),即存在1p部分单体和12q部分三体;父亲正常;母亲为ish t(1;12)(12q+,1q+;12p+,1p+),为染色体隐匿性易位携带者。结论1p36.33p36.13与12q24.31q24.33隐匿性易位会导致胎儿畸形,联合CCA、SNP和FISH技术可以更精确地对隐匿性易位患者进行遗传学分析。

关键词：多发畸形隐匿性易位常规核型分析单核苷酸多态性微阵列荧光原位杂交

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Sn-p-Li催化剂的制备过程与氧化脱氢活性的关系

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燃料化学学报 1980年第1期 26-37页

作者：周望岳李清沂刘崇娅刘俊声林景治张菊初林敏仙陈亚金羽丰赵云亭中国科学院兰州化学物理研究所石油工业部锦州石油六厂

考察了Sn-P-Li催化剂的制备过程,其中包括Sn-P胶的成胶顺序、成胶终点pH值及Sn-P-Li催化剂的水蒸汽处理条件等对其物化性质和丁烯氧化脱氢反应性能的影响。发现Sn-P-Li催化剂的物化性质和催化性能随成胶时介质的酸、碱性,成胶终点pH值... 详细信息

考察了Sn-P-Li催化剂的制备过程,其中包括Sn-P胶的成胶顺序、成胶终点pH值及Sn-P-Li催化剂的水蒸汽处理条件等对其物化性质和丁烯氧化脱氢反应性能的影响。发现Sn-P-Li催化剂的物化性质和催化性能随成胶时介质的酸、碱性,成胶终点pH值的不同而有明显的差异。水蒸汽处理能明显地改善Sn-P-Li催化剂的选择性和稳定性,但需要针对含锂量不同而选择一个最佳水蒸汽处理温度区。文中还考察并讨论了Sn-P-Li催化剂中Li组份对丁烯在该催化剂上进行氧化脱氢反应时所起的重要作用。

关键词：催化剂物化性质催化性能丁烯氧化脱氢 Sn-p-Li 水蒸汽处理 Li 制备过程

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