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Fast Blood Oxygenation through Hemocompatible Asymmetric Polymer of Intrinsic Microporosity Membranes

Research 2024年第1期2023卷 261-270页

作者： Xinxi huang junping huang Pengcheng Su Wanbin Li Guangdong Key Laboratory of Environmental Pollution and Health School of EnvironmentJinan UniversityGuangzhou 511443China

Membrane technology has attracted considerable attention for chemical and medical applications,among others.Artificial organs play important roles in medical science.A membrane oxygenator,also known as artificial lung,can replenish O_(2) and remove CO_(2) of blood to maintain the metabolism of patients with cardiopulmonary failure.However,the membrane,a key component,is subjected to inferior gas transport property,leakage propensity,and insufficient hemocompatibility.In this study,we report efficient blood oxygenation by using an asymmetric nanoporous membrane that is fabricated using the classic nonsolvent-induced phase separation method for polymer of intrinsic microporosity-1.The intrinsic superhydrophobic nanopores and asymmetric configuration endow the membrane with water impermeability and gas ultrapermeability,up to 3,500 and 1,100 gas permeation units for CO_(2) and O_(2),respectively.Moreover,the rational hydrophobic–hydrophilic nature,electronegativity,and smoothness of the surface enable the substantially restricted protein adsorption,platelet adhesion and activation,hemolysis,and thrombosis for the membrane.Importantly,during blood oxygenation,the asymmetric nanoporous membrane shows no thrombus formation and plasma leakage and exhibits fast O_(2) and CO_(2) transport processes with exchange rates of 20 to 60 and 100 to 350 ml m^(−2) min^(−1),respectively,which are 2 to 6 times higher than those of conventional membranes.The concepts reported here offer an alternative route to fabricate high-performance membranes and expand the possibilities of nanoporous materials for membrane-based artificial organs.

关键词： porosity asymmetric Oxygen

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无线传感网络中一种基于RF-GAN模型的入侵检测算法

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长沙大学学报 2024年第2期38卷 23-28页

作者：黄俊萍闽南理工学院信息管理学院福建石狮362700

针对现有无线传感网络入侵检测算法存在的效率低、精度差等问题,提出基于RFGAN模型的无线传感网络入侵检测算法。首先,采集无线传感网络运行数据,通过去噪、缺失补偿等步骤,完成对原始数据的预处理;然后,利用RF-GAN模型提取无线传感网... 详细信息

针对现有无线传感网络入侵检测算法存在的效率低、精度差等问题,提出基于RFGAN模型的无线传感网络入侵检测算法。首先,采集无线传感网络运行数据,通过去噪、缺失补偿等步骤,完成对原始数据的预处理;然后,利用RF-GAN模型提取无线传感网络运行特征;最后,通过提取特征与检测标准的匹配,得出网络入侵检测结果。理论分析及实验结果表明:优化设计方法的入侵类型误检率明显更低,入侵数据量检测误差为0.015GB,相较于现有检测算法具有一定优势。

关键词： RF-GAN模型无线传感网络网络入侵检测特征提取

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基于改进K-means数据聚类算法的网络入侵检测

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成都工业学院学报 2024年第2期27卷 58-62,97页

作者：黄俊萍闽南理工学院信息管理学院福建石狮362700

随着入侵手段的不断更新和升级,传统入侵检测方法准确率下降、检测时间延长,无法满足网络防御要求。为此,提出一种经过改进K均值(K-means)数据聚类算法,以应对不断升级的网络入侵行为。先以防火墙日志为基础转换数值,然后基于粒子群算... 详细信息

随着入侵手段的不断更新和升级,传统入侵检测方法准确率下降、检测时间延长,无法满足网络防御要求。为此,提出一种经过改进K均值(K-means)数据聚类算法,以应对不断升级的网络入侵行为。先以防火墙日志为基础转换数值,然后基于粒子群算法求取最优初始聚类中心,实现K-means数据聚类算法的改进;最后以计算得出的特征值为输入项,实现对网络入侵行为的精准检测。结果表明:K-means算法改进后较改进前的戴维森堡丁指数更小,均低于0.6,达到了改进目的。改进K-means算法各样本的准确率均高于90%,相对更高,检测时间均低于10 s,相对更少,说明该方法能够以高效率完成更准确的网络入侵检测。

关键词：改进K-means数据聚类算法防火墙日志入侵检测特征粒子群算法网络入侵检测

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正常高值血压人群生活方式决策支持系统的构建及应用

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中华护理杂志 2024年第6期59卷 654-661页

作者：沐婷玉许日祥朱倩寅陈灵杉黄君萍李志敏沈翠珍安徽医科大学护理学院合肥市230601 浙江中医药大学人文与管理学院浙江中医药大学人文与管理学院护理学院浙江中医药大学人文与管理学院医学技术与信息工程学院浙江中医药大学人文与管理学院教师教学发展中心杭州市上城区清波街道社区卫生服务中心

目的构建正常高值血压人群生活方式决策支持系统,并进行初步应用,评价其在正常高值血压人群生活方式管理中的可用性和效果。方法成立系统构建小组,以循证方法为基础,构建正常高值血压人群生活方式决策支持系统,该系统由移动端应用程序... 详细信息

目的构建正常高值血压人群生活方式决策支持系统,并进行初步应用,评价其在正常高值血压人群生活方式管理中的可用性和效果。方法成立系统构建小组,以循证方法为基础,构建正常高值血压人群生活方式决策支持系统,该系统由移动端应用程序和桌面端管理系统2个部分组成,移动端应用程序包括健康测评、决策结果(数据总览、中医保健、营养食谱、元气运动、心灵空间)和数据记录,桌面端管理系统包括用户管理与数据补录、决策管理和数据分析。2022年9月19日—11月14日,在杭州市某社区卫生服务中心招募20例正常高值血压人群进行系统的初步应用。结果共15例正常高值血压人群使用生活方式决策支持系统,使用后,其收缩压、每周中度体力锻炼时间、压力、焦虑、抑郁、健康自我管理能力、有无嗜盐行为与使用前比较,差异有统计学意义(P<0.05);大部分正常高值血压人群(14例)和社区医护人员(5名)认为生活方式决策支持系统的可用性达到“好”的水平。结论生活方式决策支持系统具有一定科学性和可用性,可为正常高值血压人群提供专业的生活方式指导,辅助改善正常高值血压人群的不良生活方式,为正常高值血压人群和社区医护人员提供辅助决策。

关键词：正常高值血压生活方式健康管理决策支持系统护理

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宏基因组二代测序技术对革兰阳性球菌重症肺炎中的诊疗价值

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中国医药指南 2024年第9期22卷 79-82页

作者：李水文黄俊平宁耀贵厦门大学附属第一医院重症医学科厦门361000 福建医科大学附属漳州市医院重症医学科漳州363000

目的探讨宏基因组二代测序(mNGS)技术在革兰阳性球菌重症肺炎中的诊疗价值。方法选取2021年5月至2023年5月于厦门大学附属第一医院重症医学科诊疗的262例重症肺炎患者为研究对象,根据支气管肺泡灌洗液(BALF)mNGS检测微生物结果,与传统... 详细信息

目的探讨宏基因组二代测序(mNGS)技术在革兰阳性球菌重症肺炎中的诊疗价值。方法选取2021年5月至2023年5月于厦门大学附属第一医院重症医学科诊疗的262例重症肺炎患者为研究对象,根据支气管肺泡灌洗液(BALF)mNGS检测微生物结果,与传统病原学检测结果相对比,比较二者在革兰阳性球菌方面的检出率,以及根据检测结果调整抗感染方案后临床治疗效果。结果mNGS对重症肺炎中革兰阳性球菌的检出率高于院内培养的方法,差异有统计学意义(P<0.05);根据mNGS检测结果将经验性抗感染治疗调整为目标性抗感染治疗。结果显示,患者生命体征好转,心率(HR)由(116.1±14.5)次/min降至(84.9±14.8)次/min、呼吸频率(RR)由(27.6±4.0)次/min降至(19.2±2.7)次/min;炎症指标下降明显,C反应蛋白(CRP)由88.0 mg/L降至36.0 mg/L,降钙素原(PCT)由13.4 ng/ml降至3.6 ng/ml,白细胞介素-6(IL-6)由83.5 pg/ml降至32.0 pg/ml;呼吸系统指标改善,动脉血氧分压(PaO_(2))由(59.2±7.0)mmHg升至(88.2±7.6)mmHg,动脉血二氧化碳分压(PaCO_(2))由44.0 mmHg降至28.0 mmHg,氧合指数PaO_(2)/FiO_(2)由154.0升至284.5;均具有统计学意义(P<0.05)。结论宏基因组二代测序技术可以提高支气管肺泡灌洗液中革兰阳性球菌的检出率,有助于提高重症肺炎的诊疗效果。

关键词：宏基因组二代测序技术支气管肺泡灌洗液革兰阳性球菌

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ChatGPT: potential, prospects, and limitations

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 6-11页

作者： Jie ZHOU Pei KE Xipeng QIU Minlie huang junping ZHANG School of Computer Science Fudan UniversityShanghai 200433China Department of Computer Science and Technology Tsinghua UniversityBeijing 100084China Shanghai Key Laboratory of Intelligent Information Processing Shanghai 200433China

Recently,OpenAI released Chat Generative Pre-trained Transformer(ChatGPT)(Schulman et al.,2022)(https://***),which has attracted considerable attention from the industry and academia because of its impressive abilities.This is the first time that such a variety of open tasks can be well solved within one large language model.To better understand ChatGPT,we briefly introduce its history,discuss its advantages and disadvantages,and point out several potential applications.Finally,we analyze its impact on the development of trustworthy artificial intelligence,conversational search engine,and artificial general intelligence.

关键词： artificial limitations intelligence

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The first principles investigation of ferrite magnetic response with mismatch stress

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Science China(Physics,Mechanics & Astronomy) 2014年第3期57卷 512-520页

作者： huang junping PENG XiangHe HU XianZhi Department of Engineering Mechanics Chongqing University School of Mechanical Engineering Chongqing Vocational Institute of Engineering Faculty of Science Kunming University of Science and Technology

The quasi-ferrite model is proposed and an appropriate PBE exchange functional with the spin density functional theory(SDFT) is selected for the calculation of the relation between magnetic moment and residual stress in ferrite using a quantum mechanics code. The relationship between ferrite magnetism and the carbon content is determined,and then a ferrite interstitial solid solution(ISS) model in a low carbon concentration state is replaced with an α- Fe model in the case of majority magnetic calculation. The band structure of the loaded-Fe is compared with that of the unloaded α-Fe. The comparison shows that the energy of Fe atomic 3d orbital changes a little,while the energy of electron orbital of iron core below 3d almost keeps unchanged. The relationship between the magnetic moment and the stress appears intermittent due to the Bragg total reflection. The change in the magnetic moment due to lattice mismatch is much larger than that caused by mechanical loading.

关键词：铁氧体第一原理磁性错配反应密度泛函理论残余应力有限元模型

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Geological conditions of natural gas accumulation and new exploration areas in the Mesoproterozoic to Lower Paleozoic of Ordos Basin, NW China

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Petroleum Exploration and Development 2019年第5期46卷 866-882页

作者： DU Jinhu LI Xiangbo BAO Hongping XU Wanglin WANG Yating huang junping WANG Hongbo WANYAN Rong WANG Jing PetroChina Exploration&Production Company Beijing 100007China Northwest Branch Research Institute of Petroleum Exploration&DevelopmentPetroChinaLanzhou 730020China Research Institute of Petroleum Exploration&Development PetroChina Changqing Oilfield CompanyXi’an 710018China Research Institute of Petroleum Exploration&Development PetroChinaBeijing 100083China

Based on field outcrop investigation,interpretation and analysis of drilling and seismic data,and consulting on a large number of previous research results,the characteristics of ancient marine hydrocarbon source rocks,favorable reservoir facies belts,hydrocarbon migration direction and reservoir-forming law in the Ordos Basin have been studied from the viewpoints of North China Craton breakup and Qilian-Qinling oceanic basin opening and closing.Four main results are obtained:(1)Controlled by deep-water shelf-rift,there are three suites of source rocks in the Ordos Basin and its periphery:Mesoproterozoic,Lower Cambrian and Middle-Upper Ordovician.(2)Controlled by littoral environment,paleo-uplift and platform margin,four types of reservoirs are developed in the area:Mesoproterozoic-Lower Cambrian littoral shallow sea quartz sandstone,Middle-Upper Cambrian–Ordovician weathering crust and dolomitized reservoir,and Ordovician L-shape platform margin reef and beach bodies.(3)Reservoir-forming assemblages vary greatly in the study area,with"upper generation and lower storage"as the main pattern in the platform,followed by"self-generation and self-storage".There are both"upper generation and lower storage"and"self-generation and self-storage"in the platform margin zone.In addition,in the case of communication between deep-large faults and the Changchengian system paleo-rift trough,there may also exist a"lower generation and upper reservoir"combination between the platform and the margin.(4)There are four new exploration fields including Qingyang paleo-uplift pre-Carboniferous weathering crust,L-shape platform margin zone in southwestern margin of the basin,Ordovician subsalt assemblage in central and eastern parts of the basin,and Mesoproterozoic–Cambrian.Among them,pre-Carboniferous weathering crust and L-shape platform margin facies zone are more realistic replacement areas,and Ordovician subsalt assemblage and the Proterozoic-Cambrian have certain potential and are worth exploring.

关键词： natural gas exploration area hydrocarbon accumulation geological conditions Mesoproterozoic Neoproterozoic Lower Paleozoic Ordos Basin

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The Palaeoclimate and Microscopic Reservoir Characteristics of Shanxi Formation Shales from Lower Permian in Qinshui Basin

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Acta Geologica Sinica(English Edition) 2015年第A1期89卷 41-44页

作者： huang junping YANG Zhanlong CHEN Qilin DI Jun BAI Yunlai LI Zhiyong huang Chenggang Research Institute of Petroleum Exploration & Development-Northwest Petrochina Lanzhou Gansu 730020 Reservoir Description Key Laboratory of China National Petroleum Corporation Lanzhou Gansu 730020

1 Introduction Qinshui Basin is the major coal bearing basin in China. And the main exploration target layer is Carboniferous- Permian. In recent years, not only in the coal-bed methane has made great progress, and al... 详细信息

关键词： PALEOCLIMATOLOGY SHALE gas RARE earth metal compounds BASINS (Geology)

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The origin and accumulation model of crude oils from oil reservoirs Chang 9 and Chang 10 in the Yanchang Formation of the Ordos Basin

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Chinese Journal Of Geochemistry 2012年第3期31卷 327-339页

作者： huang junping LI Xiangbo CHEN Qilin YANG Zhanlong WAN Yanrong WEI Lihua LONG Liwen LIU Xiaoguang Research Institute of Petroleum Exploration&Development Northwest PetroChinaLanzhou 730020China

In the lower parts of oil reservoirs Chang 9 and Chang 10 of the Yanchang Formation are oil-bearing layers newly found in oil exploration in the Ordos Basin.Based on GC,GC-MS analyses of saturated hydrocarbons from crude oils and source rocks,reservoir fluid inclusions and BasinMod,the origin of crude oils,accumulation period and accumulation models are discussed in combination with other petroleum geology data in this paper.The result shows that(1) there are two different types of crude oils in oil reservoir Chang 9 in the Longdong and Jiyuan regions:crude oils of typeⅠ(Well D86,Well A44,Well A75,Well B227,Well X62 and Well Z150) are mainly de-rived from the Chang 7 source rocks(including mudstones and shales) and distributed in the Jiyuan and Longdong regions;those of typeⅡ(Well Z14 and Well Y427),are distributed in the Longdong region,which are derived from the Chang 9 source rocks.Crude oils from oil reservoir Chang 10 in the Shanbei region are mainly derived from the Chang-9 source rocks;(2) there are two phases of hydrocarbon filling in oil reservoir Chang 9 in the Jiyuan and Longdong regions and oil reservoir Chang 10 in the Shanbei region:The first phase started at the early stage of J2z.The process of hydrocarbon filling was discontinuous in the Late Jurassic,because of the tectonic-thermal event in the Ordos Basin.The second phase was the main accumulation period,and hydrocarbons began to accumulate from the late stage of J2a to the middle-late of K1,mainly at the middle-late stage of K1;(3) there exist two types of accu-mulation models in oil reservoirs Chang 9 and Chang 10 of the Yanchang Formation:source rocks of the reservoirs in oil reservoir Chang 9 in the Jiyuan region and oil reservoir Chang 10 in the Shanbei region,the mixed type of reservoirs on the lateral side of source rocks and source rocks of the reservoirs in oil reservoir Chang 9 in the Long-dong region.

关键词：鄂尔多斯盆地原油类型成藏模式延长组油藏 GC-MS分析石油勘探陕北地区

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