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腹腔镜结直肠癌根治术联合大范围肝切除术治疗结直肠癌肝转移

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中华肝脏外科手术学电子杂志 2021年第1期10卷 77-81页

作者：郑志鹏陈雪芳叶青彭建新刁竞芳何军明广州中医药大学第二附属医院(广东省中医院)肝胆外科 510120

目的探讨同时性结直肠癌肝转移一期行腹腔镜下结直肠癌根治术联合大范围肝切除术的安全性和疗效。方法回顾性分析2016年1月至2019年12月广州中医药大学第二附属医院收治的15例同时性结直肠癌肝转移患者临床资料。其中男9例,女6例;年龄44... 详细信息

目的探讨同时性结直肠癌肝转移一期行腹腔镜下结直肠癌根治术联合大范围肝切除术的安全性和疗效。方法回顾性分析2016年1月至2019年12月广州中医药大学第二附属医院收治的15例同时性结直肠癌肝转移患者临床资料。其中男9例,女6例;年龄44~75岁,中位年龄53岁。原发病:右半结肠癌5例,左半结肠癌1例,乙状结肠癌5例,直肠癌4例。肝内转移瘤局限于左半肝9例,右半肝5例,肝中叶1例。患者均签署知情同意书,符合医学伦理学规定。患者采用一期同时行腹腔镜下结直肠癌根治联合大范围肝切除术(≥3个肝段),观察手术情况和术后疗效。结果15例均手术成功,无中转开腹。手术方式包括左半肝切除+乙状结肠切除5例,左半肝切除+Dixon术3例,左半肝切除+左半结肠切除1例,右半肝切除+右半结肠切除4例,右半肝切除+Dixon术1例,肝中叶切除+右半结肠切除1例。手术时间中位数200(150~360)min,术中出血量200(100~350)ml,术中均未输血。术后胆漏1例,胸腔积液2例,无肠漏、出血、肝衰竭、感染、死亡等严重并发症。术后住院时间10(7~15)d。术后采用Folfox6/Xelox+贝伐珠单抗方案辅助化疗。随访时间22(6~42)个月。随访中发现1例残肝转移,1例肺转移,1例死于全身多发转移,其余病例未见复发和转移。结论一期行腹腔镜结直肠癌根治术联合大范围肝切除术治疗同时性结直肠癌肝转移是安全可行的。

关键词：腹腔镜肝切除术结直肠肿瘤肿瘤转移

经Glisson鞘左、右半肝血流阻断法在腹腔镜解剖性肝中叶切除术中的应用

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肝胆胰外科杂志 2023年第1期35卷 25-29页

作者：陈雪芳熊子慧叶青王剑一何军明郑志鹏广东省中医院/广州中医药大学第二附属医院肝胆外科广东广州510120

目的比较经Glisson鞘左、右半肝血流阻断法与Pringle法行腹腔镜解剖性肝中叶切除术(LCH)治疗肝中叶肝癌的各项围手术期指标差异,评估经Glisson鞘左、右半肝血流阻断法的安全性及可行性。方法回顾性分析广东省中医院肝胆外科同一医疗团队... 详细信息

目的比较经Glisson鞘左、右半肝血流阻断法与Pringle法行腹腔镜解剖性肝中叶切除术(LCH)治疗肝中叶肝癌的各项围手术期指标差异,评估经Glisson鞘左、右半肝血流阻断法的安全性及可行性。方法回顾性分析广东省中医院肝胆外科同一医疗团队在2017年7月至2021年5月因肝中叶肝癌分别采用经Glisson鞘左、右半肝血流阻断法与Pringle血流阻断法行完全性LCH的25例肝癌患者临床资料。在LCH过程中,行经Glisson鞘左、右半肝血流阻断法12例(A组),行Pringle血流阻断法13例(B组)。结果两组患者术前的一般情况均无统计学差异(P>0.05);两组手术持续时间、肝门阻断时间、术中出血量、肿瘤切缘均无统计学差异(P>0.05)。两组术后进食时间、下床活动时间、肛门排气时间、住院时间以及并发症发生率无统计学差异(P>0.05)。在术后肝功能方面,A组术后第1、3、5天的ALT水平显著低于B组[(244.1±128.9)U/L vs(359.1±132.6)U/L,(195.5±77.8)U/L vs(378.0±143.1)U/L,(73.0±22.4)U/L vs(153.9±35.9)U/L]。A组术后第3、5天AST[(104.4±58.6)U/L vs(176.3±84.8)U/L,(38.3±11.2)U/L vs(50.6±12.7)U/L]低于B组,差异均具有统计学意义(均P<0.05)。结论LCH中运用经Glisson鞘左、右半肝血流阻断法较Pringle血流阻断法可以减轻患者术后肝功能损害,并且不会增加术中出血量、术后住院时间、手术近期相关并发症,是LCH中一种安全、有效的血流控制方法。

关键词：肝细胞癌腹腔镜肝中叶切除术 Glisson鞘半肝血流阻断法 Pringle血流阻断法

Trace elements and rare earth elements in wet deposition of Lijiang,*** region,southeastern edge of the Tibetan Plateau

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Journal of Environmental Sciences 2017年第2期29卷 18-28页

作者： junming Guo Shichang Kang Jie Huang Mika Sillanpaa hewen Niu Xuejun Sun Yuanqing he Shijing Wang Lekhendra Tripathee Key Laboratory of Tibetan Environment Changes and Land Surface Processes Institute of Tibetan Plateau ResearchChinese Academy of Sciences(CAS)Beijing 100101China State Key Laboratory of Cryospheric Sciences Cold and Arid Regions Environmental and Engineering of Research InstituteCASLanzhou 730000China CAS Center for Excellence in Tibetan Plateau Earth Sciences Beijing100101China Laboratory of Green Chemistry Lappeenranta Uniuersity of TechnologyMikkeli 50130Finland University of Chinese Academy of Sciences Beijing 100049China

In order to investigate the compositions and wet deposition fluxes of trace elements and rare earth elements（REEs） in the precipitation of the southeastern edge of the Tibetan Plateau, 38 precipitation samples were collected from March to August in 2012 in an urban site of Lijiang city in the Mt. Yulong region. The concentrations of most trace elements and REEs were higher during the non-monsoon season than during the monsoon season,indicating that the lower concentrations of trace elements and REEs observed during monsoon had been influenced by the dilution effect of increased precipitation. The concentrations of trace elements in the precipitation of Lijiang city were slightly higher than those observed in remote sites of the Tibetan Plateau but much lower than those observed in the metropolises of China, indicating that the atmospheric environment of Lijiang city was less influenced by anthropogenic emissions, and, as a consequence, the air quality was still relatively good. However, the results of enrichment factor and principal component analysis revealed that some anthropogenic activities（e.g., the increasing traffic emissions from the rapid development of tourism） were most likely important contributors to trace elements, while the regional/local crustal sources rather than anthropogenic activities were the predominant contributors to the REEs in the wet deposition of Lijiang city. Our study was relevant not only for assessing the current status of the atmospheric environment in the Mt. Yulong region, but also for specific management actions to be implemented for the control of atmospheric inputs and the health of the environment for the future.

关键词： Trace elements Rare earth elements Wet deposition Seasonal variation Lijiang city Tibetan Plateau

CONNECTIVITY OF CARTESIAN PRODUCT DIGRAPHS AND FAULT-TOLERANT ROUTINGS OF GENERALIZED HYPERCUBE

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Applied Mathematics(A Journal of Chinese Universities) 1998年第2期13卷 179-187页

作者： XU junming Department of Mathematics University of Science and Technology of China Hefei

Abstract In this paper, the problem of fault tolerant routings in fault tolerant networks is considered. A routing in a network assigns to each ordered pair of nodes a fixed path. All communication among nodes must go on this routing. When either a node or a link in a fault tolerant network fails, the communication from one node to another using this faulty element must be sent via one or more intermediate nodes along a sequence of paths determined by this routing. An important and practical problem is how to choose a routing in the network such that intermediate nodes to ensure communication are small for any fault set. Let C d be a directed cycle of order d . In this paper. The author first discusses connectivity of Cartesian product digraphs, then proves that the Cartesian product digraph C d 1 ×C d 2 ×...×C d n (d i≥2,1≤i≤n) has a routing such that at most one intermediate node is needed to ensure transmission of messages among all non faulty nodes so long as the number of faults is less than n . This is a generalization of Dolev et al's result for the n dimensional cube.

关键词： Fault-tolerant networks routings digraphs hypercube connectivity diameter

腹腔镜解剖性顺时针四切面肝中叶切除的策略与技巧

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中华肝脏外科手术学电子杂志 2020年第2期9卷 164-167页

作者：叶青何军明彭建新郑志鹏刁竞芳莫嘉强广东省中医院肝胆胰外科广州510120

目的探讨腹腔镜解剖性肝中叶切除的手术技巧与要点。方法回顾性分析2017年3月至2019年1月广东省中医院行腹腔镜解剖性肝中叶切除的12例肝癌患者临床资料。患者均签署知情同意书,符合医学伦理学规定。其中男9例,女3例;年龄43~72岁,中位年... 详细信息

目的探讨腹腔镜解剖性肝中叶切除的手术技巧与要点。方法回顾性分析2017年3月至2019年1月广东省中医院行腹腔镜解剖性肝中叶切除的12例肝癌患者临床资料。患者均签署知情同意书,符合医学伦理学规定。其中男9例,女3例;年龄43~72岁,中位年龄55岁。解剖第一肝门,显露、悬吊肝右前和左内叶肝蒂,控制出血,采用腹腔镜解剖性顺时针四切面肝中叶切除法,顺时针依次离断左侧、足侧、右侧、头侧切面。观察患者围手术期情况。结果患者均顺利完成手术,无中转开腹,无围手术期死亡。手术时间中位数为226(177~288)min,术中出血量295(50~800)ml。术后发生胸腔积液1例,胆漏1例,均通过保守治疗治愈。术后7 d肝功能基本恢复正常。术后平均住院时间(6.5±2.3)d。结论腹腔镜肝中叶切除有一定的挑战性,正确地选择肝切面,有效地控制术中出血,腹腔镜顺时针四切面肝中叶切除法是安全、可行的。

关键词：腹腔镜肝切除术失血,手术

Revealing component synergy of Ni‒Fe/black phosphorous composites synthesized by self-designed electrochemical method for enhancing photoelectrocatalytic oxygen evolution reaction

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Frontiers of Materials Science 2023年第2期17卷 143-153页

作者： he Xiao Shoufeng Xue Zimei Fu Man Zhao Li Zhang junming Zhang Haishun Wu Jianfeng Jia Nianjun Yang Key Laboratory of Magnetic Molecules&Magnetic Information Materials(Ministry of Education) School of Chemistry and Materials ScienceShanxi Normal UniversityTaiyuan 030032China Department of Chemistry Hasselt University3590 DiepenbeekBelgium

Developing high-activity and low-cost catalysts is the key to eliminate the limitation of sluggish anodic oxygen evolution reaction(OER)during electrocatalytic overall water ***,Ni‒Fe/black phosphorous(BP)composites are synthesized using a simple three-electrode system,where exfoliation of bulky BP and synthesis of NiFe composites are simultaneously *** light illumination,the optimized Ni‒Fe/BP composite exhibits excellent photoelectrocatalytic OER performance(e.g.,the overpotential is 58 mV lower than a commercial RuO_(2) electrocatalyst at a current density of 10 mA·cm^(-2)).The electron transfer on this composite is proved to follow a Ni‒BP‒Fe *** electronic structure of this Ni‒Fe/BP composite is effectively regulated,leading to optimized adsorption strength of the intermediate OH*and improved intrinsic activity for the *** with active sites on the support,this Ni‒Fe/BP composite possesses abundant electrochemical active sites and a bug surface area for the *** introduction of light further accelerates the electrocatalytic *** work provides a novel and facile method to synthesize high-performance metal/BP composites as well as the approaches to reveal their OER mechanisms.

关键词： black phosphorous (photo-)electrocatalysis oxygen evolution reaction

金华市公立医疗机构中药药事现状调查与管理建议

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中医药管理杂志 2019年第18期27卷 28-30页

作者：朱延涛王国军何俊明陈磊张庆平李永良俞金正浙江中医药大学附属金华市中医医院浙江金华321017 金华市卫生健康委员会浙江金华321000 义乌市中医医院浙江义乌322000 东阳市中医院浙江东阳322100 永康市中医院浙江永康321300

目的:调查金华市二级及以上公立医疗机构中药房建设及考核标准,建立中药药事质量考评体系,以提高我市中药药事管理质量。方法:采取全面调查的方法,依照《医院中药房基本标准》对全市10所中医医院,12所综合性医院,共22所公立医疗机构进... 详细信息

目的:调查金华市二级及以上公立医疗机构中药房建设及考核标准,建立中药药事质量考评体系,以提高我市中药药事管理质量。方法:采取全面调查的方法,依照《医院中药房基本标准》对全市10所中医医院,12所综合性医院,共22所公立医疗机构进行调研。结果:三级医院达标比例高于二级医院,中医医院达标比例高于综合性医院。中药房面积不达标、相关规章制度不完善、负责人或相关负责人资质不符合标准、专业技术人员比例不足、煎药室面积及配置不合理、部分煎药人员无资质。结论:金华市中药药事管理尚有不足之处,建议相关单位依规整改。

关键词：调查分析中药药事管理医疗机构

Interpretable Machine Learning-Assisted High-Throughput Screening for Understanding NRR Electrocatalyst Performance Modulation between Active Center and C-N Coordination

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Energy & Environmental Materials 2024年第5期7卷 263-271页

作者： Jinxin Sun Anjie Chen junming Guan Ying Han Yongjun Liu Xianghong Niu Maoshuai he Li Shi Jinlan Wang Xiuyun Zhang College of Physics Science and Technology Yangzhou UniversityYangzhou 225002China State Key Laboratory of Organic Electronics and Information Displays(KLOEID)&Institute of Advanced Materials(IAM) School of ScienceNanjing University of Posts and TelecommunicationsNanjing 210023China College of Chemistry and Molecular Engineering Qingdao University of Science and TechnologyQingdao 266042China School of Physics&Key Laboratory of Quantum Materials and Devices Ministry of EducationSoutheast UniversityNanjing 20089China

Understanding the correlation between the fundamental descriptors and catalytic performance is meaningful to guide the design of high-performance electrochemical ***,exploring key factors that affect catalytic performance in the vast catalyst space remains challenging for ***,to accurately identify the factors that affect the performance of N2 reduction,we apply interpretable machine learning(ML)to analyze high-throughput screening results,which is also suited to other surface reactions in *** expound on the paradigm,33 promising catalysts are screened from 168 carbon-supported candidates,specifically single-atom catalysts(SACs)supported by a BC_(3)monolayer(TM@V_(B/C)-N_(n)=_(0-3)-BC_(3))via high-throughput ***,the hybrid sampling method and XGBoost model are selected to classify eligible and non-eligible *** feature interpretation using Shapley Additive Explanations(SHAP)analysis,two crucial features,that is,the number of valence electrons(N_(v))and nitrogen substitution(N_(n)),are screened *** SHAP analysis and electronic structure calculations,the synergistic effect between an active center with low valence electron numbers and reasonable C-N coordination(a medium fraction of nitrogen substitution)can exhibit high catalytic ***,six superior catalysts with a limiting potential lower than-0.4 V are *** workflow offers a rational approach to obtaining key information on catalytic performance from high-throughput screening results to design efficient catalysts that can be applied to other materials and reactions.

关键词： electrochemical nitrogen reduction feature engineering high-throughput screening machine learning

Blow-up for the solutions to nonlinear parabolic-elliptic system modeling chemotaxis

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International Journal of Biomathematics 2017年第7期10卷 191-203页

作者： Ziqian Huang junming Zhu Department of Physics Guangxi Teachers Education University Nanning 530001 P. R. China Department of Mathematics Luoyang Normal University Luoyang 471022 P. R. China

In this paper, we study the blow-up solutions for the simplified Keller-Segel system modeling chemotaxis. We prove that there is the occurrence of δ blow-up to the radially symmetric solutions. We also prove that blo... 详细信息

关键词： Chemotaxis parabolic-elliptic blow-up.