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Overview of coals as carbon anode materials for sodium-ion batteries

Clean Energy 2024年第4期8卷 197-218页

作者： junli Kong Zhijiang su Chunwei Dong Quanbin Chen Guanghong Pan National ins.itute of Clean-and-Low-Carbon Energy Beijing 102211China

Energy storage is an important technology in achieving carbon-neutrality *** with lithium-ion batteries,the raw materials of sodium-ion batteries are abundant,low-cost,and highly ***,their costs are expected to be further reduced as large-scale applications take off,making them viable for energy storage *** primary anode material for sodium-ion batteries.is hard carbon,which has a high sodium-ion storage capacity but is relatively expensive,limiting its applications.in energy *** order to widen the applications of sodium-ion batteries.in energy storage and other fields.it is particularly important to develop anode materials that have both high performance and low ***,with abundant reserves and worldwide availability,can serve as low-cost carbon sources for anode ***,coals of different grades of metamorphism have different structural characteris.ics that can be tailored for the structural characteris.ics of coal-based anode materials for sodium-ion bat*** research on tailoring coals as the anode materials for sodium-ion batteries.is summarized and the recent progress made towards mitigating the exis.ing issues.is analysed in this ***,the impacts of different grades of metamorphism on the sodium-ion storage performance of coal-based anode materials prepared using direct carbonization are discussed in *** on improving the electrochemical performances of coal-based anode materials through pore and microcrystalline structure controls and surface as well as.interface modifications are ***,the advantages and disadvantages of different preparation methods are *** make the industrial applications of coal-based anode materials for sodium-ion batteries more viable,the importance of the de-as.ing process.is.introduced.

关键词： coals sodium-ion batteries anodes structure controls de-as.ing process

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Loss of GATA6-mediated up-regulation of UTX promotes pancreatic tumorigenesis and progres.ion

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Genes & Diseases 2024年第2期11卷 921-934页

作者： Hui-Qing Zhang Fanyang Kong Xiangyu Kong Tingting Jiang Muyuan Ma shaojiang Zheng junli Guo Keping Xie The Third Department of Medical Oncology Jiangxi Cancer HospitalNanchangJiangxi 330006China Departments of Gastroenterology Changhai HospitalSecond Military Medical UniversityShanghai 200433China Center for Pancreatic Cancer Research The South China University of Technology School of MedicineGuangzhouGuangdong 510006China Hainan Clinical Medical Research Center of the First Affiliated Hos.ital Hainan Women and Children's Medical CenterHainan Medical UniversityHaikouHainan 570102China Key Laboratory of Tropical Cardiovascular Diseases Research of Hainan Province Key Laboratory of Emergency and Trauma of Ministry of EducationHainan Medical UniversityHaikouHainan 571199China

Ubiquitously transcribed tetratricopeptide repeat on chromosome X(UTX),also known as lysine(K)-specific demethylase 6A(KDM6A),functions as a tumor suppressor gene or oncogene depending on the tumor type and ***,its tumor-suppres.ive mechanisms remain largely ***,we inves.igated the clinical significance and biological effects of UTX expres.ion in pancreatic ductal adenocarcinoma(PDA)and determined the potential mechanisms of its *** expres.ion and its association with clinicopathologic characteris.ics of PDA patients were analyzed using *** mRNA and protein expres.ion and their regulation in PDA cell lines were measured using quantitative polymerase chain reaction and Western blot *** biological functions of UTX in PDA cell growth,migration,and invasion were determined using gain-and loss-of-function assays with both in vitro and in vivo animal *** expres.ion was reduced in human PDA cell lines and *** UTX expres.ion was associated with poor differentiation and prognosis.in *** UTX expres.ion inhibited PDA proliferation,migration,and invasion in vitro and PDA growth and metastasis.in vivo,whereas knockdown of UTX expres.ion did the ***,UTX expres.ion was trans-activated by GATA6 ***6-mediated PDA progres.ion could be blocked,at least partially,by silencing UTX *** conclusion,loss of GATA6-mediated UTX expres.ion was evident in human PDA and restored UTX expres.ion suppressed PDA growth and ***,UTX is a tumor suppressor in PDA and may serve as a prognos.ic biomarker and therapeutic target.

关键词： Growth invasion Metastasis Pancreatic cancer UTX

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Dynamics and functionalities of bacterial community during foxtail millet dough fermentation by metagenomic analysis

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Journal of Future Foods 2024年第4期4卷 343-352页

作者： junli Liu Wei Zhao Aixia Zhang Pengliang Li Jingke Liu ins.itute of Biotechnology and Food s.ience Hebei Academy of Agriculture and Forestry SciencesShijiazhuang 050000China

sourdough flavors were closely related to microbial *** microbial diversity of foxtail millet dough during fermentation has never been ***,the metabolic potential and diversity of the bactenial community were analyzed by metagenomic during dough *** was the dominant phylum in the dough,within heterofementative lactic acid bacteria(***,Limosilactobacillus,Pediococcus and Lactobacillus)as the most abundant *** was gradually inhibited after ***_crustorum was notably found abundant during dough ***_fermentum increased markedly during fermentation,while Companilactobacillus_cnustorum decreased *** futher exploration,genes associated with metabolism were annotated through ***,Companilactobacillus and Pediococcus were actively engaged in glycolysis(ko00010),starch and sucrose metabolism(ko00500),and pyruvate metabolism(ko00620),leading in part to 1actic and acetic acid acumulations and dough *** and Lactiplantibacillus were the main contributors to key aninopeptidases ox/and transaminases.involved in amino acid metabolism,which was nesponsible for flavor metabolite *** study will provide an enhanced understanding of the predominance and diversity of dough bactenial communities,and contribute to future strain screening in the dough for better flavor.

关键词： sourdough Foxtail millet Metagenomics Gilycolysis Amino acid biosynthesis

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The Effect of Transverse Tibial Bone Transfer in the Treatment of Diabetic Foot

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Journal of Bios.iences and Medicines 2024年第4期12卷 116-122页

作者： Qiaoyu Cheng junli Xue Department of Endocrinology Affiliated Jingzhou Hospital of Yangtze University Jingzhou China

To analyse the effectiveness of performing a transverse tibial bone graft in the treatment of patients with diabetic foot. We retrospectively analysed the clinical details of 51 diabetic foot patients.in our hos.ital from February 2023 to February 2024 and divided them into two groups according to the different treatment modalities, in which the control group received open debridement and the treatment group received transverse tibial bone transfer and compared the differences between the two groups. There were large differences.in VAs score, Toronto Clinical symptom score, quality of life score, internal lumen diameter, blood flow velocity in the affected limb, perfusion volume, vascular endothelial growth factor, epidermal growth factor and CRP between the two groups after surgery (P ients with diabetic foot should be treated with transverse tibial bone grafting, which is safer and more effective and can have a significant impact on improving the status of the affected limb, the inflammation and the patient’s quality of life.

关键词： Diabetic Foot Transverse Tibial Bone Grafting Treatment Efficacy Prognosis

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Multidis.iplinary integration of frontier technologies facilitating the development of anesthesiology and perioperative medicine in aging society

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Fundamental Research 2024年第4期4卷 795-796页

作者： Lize Xiong junli Cao Hailong Dong Weihong song Dong Ming Translational Research ins.itute of Brain and Brain-Like intelligence and Department of Anesthesiology and Perioperative Medicine Shanghai Fourth People's Hospital Affiliated to Tongji University School of MedicineShanghai 200434China Jiangsu Province Key Laboratory of Anesthesiology Xuzhou Medical UniversityXuzhou 221004China Department of Anesthesiology and Perioperative Medicine Xijing Hospitalthe Fourth Military Medical UniversityXi'an 710032China The second Affliated Hos.ital and Yuying Children's Hos.ital Institute of AgingKey Laboratory of Alzheimer's Disease of Zhejiang ProvinceWenzhou Medical UniversityWenzhou325035China state Key Laboratory of Advanced Medical Materials and Devices Medical SchoolTianjin UniversityTianjin 300072China Haihe Laboratory of Brain-Computer interaction and Human-Machine integration Tianjin 300380China

The population aged 60 and over in China reached approximately 297 million in 2023 according to the National Bureau of statis.ics,accounting for 21.1%of the national *** population aged 65 and over was about 217 million,accounting for 15.4%[1].it is es.imated that by 2035,China will have an elderly population of over 400 million,accounting for more than 30%of the total population,thereby entering a stage of severe *** brings many challenges to the society,especially in terms of medical care for elderly *** continuous advancement of s.ience and technology,especially the breakthrough in basic research as well as new technologies and interdis.iplinary integration,has brought new opportunities for the development of various profes.ional *** better address the challenges of anesthesia and perioperative medicine in the aging era and to accelerate the rehabilitation of patients while maintaining life and health services.it is crucial to promote interdis.iplinary integration.

关键词： breakthrough frontier thereby

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The 4^(th)CCL Organic Chemistry Forum held in Zhangye

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Chinese Chemical Letters 2024年第8期35卷 3-6页

作者： Yingxiao Zong Yangfei Wei Xiaoqing Liu Junke Wang Huanfang Guo junli Wang Zhuangzhi s.i Tao Tu Cheng Yang Chongyang Wang Leyong Wang Key Laboratory of Hexi Corridor Resources Utilization of Gansu School of Chemistry and Chemical EngineeringHexi UniversityZhangye 734000China ins.itute of Materia Medica Chinese Academy of Medical SciencesBeijing 100050China school of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210023China Department of Chemistry Fudan UniversityShanghai 200438China College of Chemistry Sichuan UniversityChengdu 610064China ins.itute of Chemistry Chinese Academy of SciencesBeijing 100190China

The first Chinese Chemical Letters(CCL)Organic Chemistry Forum was held in Xiamen of Fujian in Jan.2018,followed by the successful events.in Zhengzhou of Henan in Dec.2019 and Linzhi of Tibet in July *** series of forums aim to build a high-level organic chemistry academic exchange platform for(Chinese)youthful organic chemists,fully showcase their latest fron-tier achievements,and enhance the international level of organic chemistry in *** the same time,the convening of the series of forums has also played a positive role in promoting the devel-opment of China’s s.ientific journal publis.ing,accelerating the re-alization of the strategic goal of building a world-class journal.

关键词： journal Forum Xiamen

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The Effect of Tuberculosis.infection on Pancreatic Beta-Cell Function in Patients with Type 2 Diabetes Mellitus

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Advances.in Bios.ience and Biotechnology 2024年第2期15卷 129-139页

作者： Mengdan Kong Ailin Zhong s.ilin Qu junli Xue Department of Endocrinology Jingzhou Hospital Affiliated to Changjiang University Jingzhou China Department of Tuberculosis The First People’s Hospital of Jingzhou City Jingzhou China Department of Endocrinology The Third People’s Hospital of Jingzhou City Jingzhou China

Objective: The aim of this study is to inves.igate how individuals with type 2 diabetes mellitus’ pancreatic β-cell function index and insulin resistance index are affected by tuberculosis.infection. Methods: The study group consisted of 89 patients with type 2 diabetes mellitus and tuberculosis.infection who were admitted to Jingzhou Chest Hos.ital between March 2019 and March 2021. Gender and duration of diabetes were matching conditions. The control group was made up of 89 patients with type 2 diabetes who were admitted to Jingzhou Central Hos.ital’s endocrinology department during the same period. The two patient groups provided general information such as gender, age, length of diabetes, and blood biochemical indexes such as glycosylated hemoglobin (HbA1c), fas.ing glucose (FPG), and fas.ing C-peptide (FC-P). The HOMA calculator was used to calculate the HOMA-β and the HOMA-iR, and intergroup comparisons and correlation analyses were carried out. Results: Regarding gender, age, disease duration, FC-P, and HbA1c, the differences between the two groups were not statis.ically significant (P > 0.05). However, BMi, FPG, HOMA-β, and HOMA-iR showed statis.ically significant differences (P in comparison to the control group, the study group’s HOMA-β was lower and its HOMA-iR was greater. According to spearman’s correlation analysis, HOMA-β had a negative association (P th FPG, HbA1c, and the length of the disease, and a positive correlation with BMi and FC-P. A positive correlation was found between HOMA-iR and BMi, FPG, and FC-P (P s well as a correlation with the length of the disease (P > 0.05) and HbA1c. Conclusions: in type 2 diabetes mellitus combined with tuberculosis.infection, the patients had higher FPG levels and lower FC-P levels, the secretory function of pancreatic β-cells was more severely impaired, and insulin resistance was more obvious.

关键词： Tuberculosis.infection Type 2 Diabetes Mellitus Pancreatic β-Cell Function insulin Resistance

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A rare inter-haplotypic recombination at the s-locus contributed to the loss of self-incompatibility in trifoliate orange

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Plant Communications 2024年第9期5卷 16-20页

作者： Jianbing Hu Furong Guo Zezhen Du Peng Chen Chunmei s.i Jinzhi Zhang junli Ye Xiuxin Deng Robert M.Larkin Wenbiao Jiao Zongcheng Lin Maurice Bosch Lijun Chai National Key Laboratory for Germplasm innovation and Utilization of Horticultural Crops College of Horticulture and Forestry SciencesHuazhong Agricultural UniversityWuhan 430070P.R.China Hubei Hongshan Laboratory Wuhan 430070P.R.China Horticultural ins.itute Hunan Academy of Agricultural SciencesChangsha 410125P.R.China ins.itute of Biological Environmental and Rural Sciences(IBERS)Aberystwyth UniversityAberystwyth SY233FLUK

Dear Editor,in trans-specific s-haplotypes,crossover recombination at the s-locus,which controls self-incompatibility,has been thought to be highly ***,we discovered a previously unreported super s haplotype,derived from a rare inter-haplotypic recombination event,that contained two complete s.ites of functional s-RNase and sLF genes and could break the si response in trifoliate orange through“self-recognition”within the same pollen.

关键词： orange crossover trifolia

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Effect of transcranial direct current s.imulation on postoperative sleep disturbance in older patients undergoing lower limb major arthroplasty:a prospective,double-blind,pilot,randomised controlled trial

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General Psychiatry 2024年第2期37卷 224-233页

作者： Jie Yang Mingshu Tao Rongguang Liu Jiaxing Fang Chunyan Li Dexian Chen Qi Wei Xingyu Xiong Wenxin Zhao Wen Tan Yuan Han Hongxing Zhang He Liu song Zhang junli Cao Department of Anesthesiology The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsuChina Department of Anesthesiology Hospital of Chengdu University of Traditional Chinese Medicine&Traditional Chinese Medicine Hospital of Sichuan ProvinceChengduSichuanChina NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs&Jiangsu Province Key Laboratory of Anesthesiology&Jiangsu Key Laboratory of Applied Technology of Anesthesia and Analgesia Xuzhou Medical UniversityXuzhouJiangsuChina Department of Anesthesiology Eye&ENT Hospital of Fudan UniversityShanghaiChina Department of Anesthesiology&Clinical Research Center for Anesthesia and Perioperative Medicine&Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University||Huzhou Central Hospital||The Affiliated Huzhou HospitalZhejiang University School of Medicine||Affiliated Central Hospital Huzhou UniversityHuzhouZhejiangChina Department of Anesthesiology Renji Hospital School of MedicineShanghai Jiao Tong UniversityShanghaiChina

Background Postoperative sleep disturbance(PsD)is a common and serious postoperative complication and is associated with poor postoperative *** This study aimed to inves.igate the effect of transcranial direct current s.imulation(tDCs)on PsD in older patients undergoing lower limb major *** in this prospective,double-blind,pilot,randomised,sham-controlled trial,patients 65 years and over undergoing lower limb major arthroplasty were randomly as.igned to receive active tDCs(a-tDCs)or sham tDCs(s-tDCs).The primary outcomes were the objective sleep measures on postoperative nights(N)1 and *** 116 inpatients were assessed for eligibility,and a total of 92 patients were enrolled;47 received a-tDCs and 45 received *** improved PsD by altering the following sleep measures.in the a-tDCs and s-tDCs groups;the respective comparisons were as follows:the promotion of rapid eye movement(REM)sleep time on N1(64.5(33.5-105.5)vs 19.0(0.0,45.0)min,F=20.10,ps 30.0(1.3-59.3)min,F=12.55,psleep time on N1(506.0(408.0-561.0)vs 392.0(243.0-483.5)min,F=14.13,ps 346.0(286.5-517.5)min,F=7.36,p=0.007);the deep sleep time on N1(130.0(103.3-177.0)vs 42.5(9.8-100.8)min,F=24.4,ps 57.5(23.3-106.5)min,F=8.4,p=0.004);and the percentages of light sleep and REM sleep on N1 and N2(pstoperative depres.ion and anxiety scores did not differ significantly between the two *** significant adverse events were *** in older patients undergoing lower limb major arthroplasty,a single ses.ion of anodal tDCs over the left dorsolateral prefrontal cortex showed a potentially prophylactic effect in improving postoperative short-term objective sleep ***,this benefit was temporary and was not maintained over time.

关键词： sleep s.imulation postoperative

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Molecular features of gastroenteropancreatic neuroendocrine carcinoma: A comparative analysis with lung neuroendocrine carcinoma and diges.ive adenocarcinomas

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Chinese Journal of Cancer Research 2024年第1期36卷 90-102页

作者： Jianwei Zhang Hanxiao Chen junli Zhang sha Wang Yanfang Guan Wenguang Gu Jie Li Xiaotian Zhang Jian Li Xicheng Wang Zhihao Lu Jun Zhou Zhi Peng Yu sun Yang shao Lin shen Minglei Zhuo Ming Lu Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Department of Radiation Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeShenzhen 518172China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department I of Thoracic OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Medical Department Nanjing Geneseeq Technology Inc.Nanjing 210061China Geneplus-Beijing Beijing 102200China state Key Laboratory of Holis.ic integrative Management of Gastrointes.inal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchDepartment of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of PathologyPeking University Cancer Hospital&InstituteBeijing 100142China

Objective: There is an ongoing debate about whether the management of gastroenteropancreatic(GEP)neuroendocrine carcinoma(NEC) should follow the guidelines of small-cell lung cancer(sCLC). We aim to identify the genetic differences of GEPNEC and its ***: We recruited GEPNEC patients as the main cohort, with lung NEC and diges.ive adenocarcinomas as comparative cohorts. All patients undergone next-generation sequencing(NGs). Different gene alterations were compared and analyzed between GEPNEC and lung NEC(LNEC), GEPNEC and adenocarcinoma to yield the remarkable ***: We recruited 257 patients, including 99 GEPNEC, 57 LNEC, and 101 diges.ive *** the mutations, KRAs, RB1, TERT, iL7R, and CTNNB1 were found to have different gene alterations between GEPNEC and LNEC samples. specific genes for each site were revealed: gastric NEC(TERT amplification),colorectal NEC(KRAs mutation), and bile tract NEC(ARiD1A mutation). The gene disparities between small-cell NEC(sCNEC) and large-cell NEC(LCNEC) were KEAP1 and CDH1. Diges.ive adenocarcinoma was also compared with GEPNEC and suggested RB1, APC, and KRAs as significant genes. The TP53/RB1 mutation pattern was associated with first-line effectiveness. Putative targetable genes and biomarkers.in GEPNEC were identified in22.2% of the patients, and they had longer progres.ion-free survival(PFs) upon targetable treatment [12.5 months vs. 3.0 months, HR=0.40(0.21-0.75), P=0.006].Conclusions: This work demonstrated striking gene dis.inctions.in GEPNEC compared with LNEC and adenocarcinoma and their clinical utility.

关键词： Neuroendocrine carcinoma gastroenteropancreatic lung genetic alterations molecular markers

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