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Influence of Temperature, Moisture, and Light Conditions on the Germination of Seeds of <i>Erythronium japonicum</i>Decne

第十五届国际药理学大会

作者： junko Yoshida Takaharu Ishibashi Matomo Nishio Dept.Pharmacol. Kanazawa Med.Univ. Uchinada Ishikawa 920- 0293 Japan Dept.Pharmacol. Kanazawa Med.Univ. Uchinada Ishikawa 920- 0293 Japan Dept.Pharmacol. Kanazawa Med.Univ. Uchinada Ishikawa 920- 0293 Japan

＜正＞ We have previously shown that amlodipine, an L - type voltage - dependent Ca2+ channel blocker, inhibited the cell growth of human epidermoid carcinoma A431 cells that lack relevant Ca2+ channels. In this study, we examined the effect of amlodipine on cell cycle distribution and cell cycle - specific protein expression in A431 cells by flow cytometric analysis and Western blotting, respec- tively. Treatment with amlodipine （20-30 uM for 24 hrs） induced Gl phase accumulation, which was associated with decreases in the phosphorylated form of retinoblastoma protein （pRB）, a regulator of Gl - S - phase transition and in protein levels of cyclin Dl and cyclindependent kinase 4 （CDK4）, Gl - specific cell- cycle proteins. On the other hand, the expression of p21Wafl/Cipl, an inhibitor protein of CDK/cyclin complexes, was increased by amlodipine. These data suggest that amlodipine induced the expression of p21Wafl/Cipl and con-comitantly inhibited the CDK4 and CDK4 - mediated phosphorylation of pRB, which resulted in Gl cell - cycle arrest and growth inhibition.

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Open Journal of Forestry 2018年第1期8卷 105-116页

作者： Yumiko Kanazawa junko Abe Shinji Kobayashi Kazue Shibuya Kojiro Suzuki Department of Landscape Architecture Science Faculty of Regional Environmental Science Tokyo University of Agriculture Tokyo Japan

Erythronium japonicum is a representative species of spring ephemeral, forest floor plants in substitution forests in Japan. Seed germination tests were conducted to observe the effects of temperature, light, and moisture content on the germination of E. japonicum. E. japonicum seeds did not germinate at constant temperatures of 5°C, 10°C, 15°C, 20°C, or 25°C. Seeds germinated at 5°C and 10°C after storage at 20°C for 1 or 2 months. Seed germinability was affected by desiccation to only 40% moisture content. Seeds germinated well in both light and dark conditions. Conditions under the leaf litter layer showed unique characteristics of temperature, light, and moisture content. The temperature was around 20°C under the leaf litter layer, even though it was 30°C above. The moisture content under the leaf litter layer was higher than that above. The leaf litter blocked out the sunlight. The temperature of 20°C necessary for E. japonicum germination occurred below, but not above, the leaf litter layer. The avoidance of decreasing in germinability from reduced seed moisture content in a short time is consistent with the high moisture conditions under the leaf litter layer. The leaf litter layer plays an important role in providing optimal conditions of temperature, light, and moisture content for the germination of E. japonicum seeds.

关键词： Erythronium japonicum Leaf Litter Layer Life History Seed Germination Spring Ephemeral

Collagen-Based Fuel Cell and Its Proton Transfer

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Materials Sciences and Applications 2017年第11期8卷 747-756页

作者： Yasumitsu Matsuo Hiroki Ikeda Takashi Kawabata junko Hatori Hiroshi Oyama Department of Life Science Faculty of Science & Engineering Setsunan University Neyagawa Japan

We have fabricated the fuel cell based on the tissue derived biomaterial “collagen” and investigated its proton transfer. It was found that “collagen” becomes the electrolyte of fuel cell in the humidified condition. The power density of the fuel cell becomes typically 8.6 W/m2 in the 80% humidity. Further, these results indicate that collagen exhibits proton conductivity in the humidified condition. Both of proton conductivity and dielectric constant increase by the increase of humidity. From the analyses of the frequency dependence of AC conductivity, it was found that proton conductivity and the dielectric dispersion observed in the humidified condition are caused by the formation of the water bridge, which is bonded with the collagen peptide chain. Considering that hydration induces the formation of the water bridge and that increases proton conductivity and dielectric constant, it is deduced that proton transfer in the fuel cell based on collagen is caused by the breaking and rearrangement of hydrogen bond in the water bridge.

关键词： Fuel Cell Proton Conductor Electrolyte Biomaterials

Real-time virtual sonography visualization and its clinical application in biliopancreatic disease

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World Journal of Gastroenterology 2013年第42期19卷 7419-7425页

作者： Atsushi Sofuni Takao Itoi Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Syujiro Tsuji Nobuhito Ikeuchi Reina Tanaka junko Umeda Ryosuke Tonozuka Mitsuyoshi Honjo Shuntaro Mukai Fuminori Moriyasu Department of Gastroenterology and Hepatology Tokyo Medical UniversityTokyo 160-0023Japan

AIM:To evaluate the usefulness of real-time virtual sonography(RVS)in biliary and pancreatic ***:This study included 15 patients with biliary and pancreatic *** can be used to observe an ultrasound image in real time by merging the ultrasound image with a multiplanar reconstruction computed tomography(CT)image,using pre-scanned CT volume *** ultrasound used was EUB-8500with a convex probe *** RVS images were evaluated based on 3 levels,namely,excellent,good and poor,by the displacement in ***:By combining the objectivity of CT with free scanning using RVS,it was possible to easily interpret the relationship between lesions and the surrounding organs as well as the position of vascular *** resulting evaluation levels of the RVS images were12 excellent(pancreatic cancer,bile duct cancer,cholecystolithiasis and cholangiocellular carcinoma)and 3 good(pancreatic cancer and gallbladder cancer).Compared with conventional B-mode ultrasonography and CT,RVS images achieved a rate of 80%superior visualization and 20%better ***:RVS has potential usefulness in objective visualization and diagnosis in the field of biliary and pancreatic diseases.

关键词： Biliary and pancreatic disease Computed tomography-multiplanar reconstruction image Navigation Real-time ultrasound image Real-time virtual sonography

Technologies to Support Community Flood Disaster Risk Reduction

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International Journal of Disaster Risk Science 2016年第2期7卷 198-204页

作者： Ian McCallum Wei Liu Linda See Reinhard Mechler Adriana Keating Stefan Hochrainer-Stigler junko Mochizuki Steffen Fritz Sumit Dugar Miguel Arestegui Michael Szoenyi Juan-Carlos Laso Bayas Peter Burek Adam French Inian Moorthy International Institute for Applied Systems Analysis (IIASA) Practical Action Consulting South Asia Practical Action Latin America Zurich Insurance Group

Floods affect more people globally than any other type of natural hazard. Great potential exists for new technologies to support flood disaster risk reduction. In addition to existing expert-based data collection and analysis, direct input from communities and citizens across the globe may also be used to monitor, validate, and reduce flood risk. New technologies have already been proven to effectively aid in humanitarian response and recovery. However, while ex-ante technologies are increasingly utilized to collect information on exposure, efforts directed towards assessing and monitoring hazards and vulnerability remain limited. Hazard model validation and social vulnerability assessment deserve particular attention. New technologies offer great potential for engaging people and facilitating the coproduction of knowledge.

关键词： Crowdsourcing Disaster risk reduction Flood resilience Social media Volunteered geographic information (VGI)

Gas-forming liver abscess associated with rapid hemolysis in a diabetic patient

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World Journal of Diabetes 2014年第2期5卷 224-229页

作者： Miwa Kurasawa Takashi Nishikido junko Koike Shin-ichi Tominaga Hiroyuki Tamemoto Department of Interna Medicine Nishi-agatsuma Welfare Hospital Naganohara machi Agatsuma-gun Gunma Prefecture 377-1308 Japan Clinical Laboratory Nishi-agatsuma Welfare Hospital Naganohara-machi Agatsuma-gun Gunma Prefecture 377-1308 Japan Department of Biochemistry Jichi Medical University

We experienced a case of liver abscess due to Clostridium perfringens(CP) complicated with massive hemolysis and rapid death in an adequately controlled type2 diabetic patient. The patient died 6 h after his first visit to the hospital. CP was later detected in a blood culture. We searched for case reports of CP septicemia and found 124 cases. Fifty patients survived, and 74died. Of the 30 patients with liver abscess, only 3 cases survived following treatment with emergency surgica drainage. For the early detection of CP infection, detection of Gram-positive rods in the blood or drainage fluid is important. Spherocytes and ghost cells indicate intravascular hemolysis. The prognosis is very poor once massive hemolysis occurs. The major causative organisms of gas-forming liver abscess in diabetic patients are Klebsiella pneumoniae(K. pneumoniae) and Escherichia coli(E. coli). Although CP is relatively rare,the survival rate is very poor compared with those of K. pneumoniae and E. coli. Therefore, for every case that presents with a gas-forming liver abscess, the possibility of CP should be considered, and immediate aspiration of the abscess and Gram staining are important.

关键词： Liver abscess Gas-forming Clostridium perfringens Hemolysis Diabetes

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“朝贡”与“条约”之间

南洋问题研究 2007年第4期 64-76页

作者：小泉顺子京都大学东南亚研究所

本文根据暹罗方面的史料,围绕两国间有关"朝贡"与"条约"的交涉,重新探讨19世纪中期至20世纪初期中国与暹罗的关系。

关键词：朝贡条约中暹关系

护士在唇腭裂患儿中应用奶瓶喂养技术现状的调查研究

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International Journal of Nursing Sciences 2023年第1期10卷 82-88页

作者： Shingo Ueki Ayaka Fujita Yukari Kumagai Yumi Hirai Eri Tashiro junko Miyata Department of Health Sciences Faculty of Medical SciencesKyushu UniversityFukuokaJapan School of Nursing Daiichi University of PharmacyFukuokaJapan Department of Nursing Osaka University Dental HospitalOsakaJapan

目的调查护士对有喂养困难的唇腭裂患儿所采用的临床奶瓶喂养技术现状。方法采用质性描述性研究设计。于2021年12月至2022年1月,向日本1109所设有产科、新生儿科或小儿牙科病房的医院分别发放匿名问卷。参与者是具有5年以上唇腭裂患儿... 详细信息

目的调查护士对有喂养困难的唇腭裂患儿所采用的临床奶瓶喂养技术现状。方法采用质性描述性研究设计。于2021年12月至2022年1月,向日本1109所设有产科、新生儿科或小儿牙科病房的医院分别发放匿名问卷。参与者是具有5年以上唇腭裂患儿护理工作经验的护士。问卷包括喂养技术4个方面的开放式问题,包括:奶瓶喂养前的准备、乳头插入方法、吸吮帮助和停止奶瓶喂养的标准。根据意义相似性对资料进行分类和分析。结果共获得410份有效问卷。资料分析结果显示,奶瓶喂养前的准备工作分为7个类别(如,改善患儿的口腔运动、保持患儿平稳呼吸),27个子类别;在乳头插入方法中,分为4个类别(如,用乳头在口腔内形成负压封闭裂口、插入乳头时不接触裂口),11个子类别;在吸吮帮助中,分为5个类别(如,促进觉醒、口腔产生负压),13个子类别;在停止奶瓶喂养的标准中,分为5个类别(如,觉醒水平降低、生命体征变差),16个子类别。96.0%护士希望学习唇腭裂患儿的奶瓶喂养技术。结论本研究确定了多项用于唇腭裂喂养困难患儿的奶瓶喂养技术。然而,这些技术之间存在相互矛盾,方法的有效性也未得到评估。未来需要进行干预研究,以确定各项技术的益处或潜在的危害。

关键词：瓶饲唇裂腭裂儿童,住院护士

Peripheral Nerve Block Combined with Epidural Anesthesia for Incarcerated Inguinal Hernia Repair in a Patient with Severe Chronic Obstructive Pulmonary Disease: A Case Report

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Open Journal of Anesthesiology 2022年第3期12卷 105-112页

作者： Yui Ikuta Hideya Kato Yuko YNishiwaki junko Tamura Ryuhei Araki Shinji Nozuchi Department of Anesthesiology Saiseikai Shiga Hospital Ritto Japan

Background: Invasive mechanical ventilation worsens prognosis in patients with severe chronic obstructive pulmonary disease (COPD). To avoid complications in these patients, anesthesia should be carefully considered. Case presentation: A 78-year-old man with COPD presented with dyspnea and pain from the epigastric to the umbilical regions. He was diagnosed with left incarcerated inguinal hernia and underwent radical inguinal hernia repair and surgical ileus treatment. To avoid general anesthesia with tracheal intubation, epidural anesthesia was combined with peripheral nerve blocks. An epidural catheter was inserted from T12/L1, and ilioinguinal-iliohypogastric and genitofemoral nerve blocks were performed under ultrasound guidance. No post-surgery complications or pain symptoms were noted. Conclusions: General anesthesia would likely have been challenging due to the patient’s COPD;however, management of peritoneal traction pain is difficult using peripheral nerve block alone. By combining epidural anesthesia with peripheral nerve blocks, we safely performed a procedure in a patient with severe COPD while avoiding invasive positive pressure ventilation.

关键词： COPD Hernia Repair Peripheral Nerve Block Epidural Anesthesia