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Chemical characterization and source apportionment of atmospheric submicron particles on the western coast of Taiwan Strait, China

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Journal of Environmental Sciences 2017年第2期29卷 293-304页

作者： Liming Cao Qiao Zhu Xiaofeng huang junjun Deng Jinsheng Chen Youwei Hong Lingling Xu Lingyan He Key Laboratory for Urban Habitat Environmental Science and Technology School of Environment and Energy Peking University Shenzhen Graduate School Center for Excellence in Urban Atmospheric Environment Institute of Urban Environment Chinese Academy of Sciences

Taiwan Strait is a special channel for subtropical East Asian Monsoon and its western coast is an important economic zone in China. In this study, a suburban site in the city of Xiamen on the western coast of Taiwan Strait was selected for fine aerosol study to improve the understanding of air pollution sources in this region. An Aerodyne high-resolution time-of-flight aerosol mass spectrometer（HR-To F-AMS） and an Aethalometer were deployed to measure fine aerosol composition with a time resolution of 5 min from May 1to 18, 2015. The average mass concentration of PM1 was 46.2 ± 26.3 μg/m^3 for the entire campaign. Organics（28.3%）, sulfate（24.9%）, and nitrate（20.6%） were the major components in the fine particles, followed by ammonium, black carbon（BC）, and chloride. Evolution of nitrate concentration and size distribution indicated that local NOx emissions played a key role in high fine particle pollution in Xiamen. In addition, organic nitrate was found to account for 9.0%–13.8% of the total measured nitrate. Positive Matrix Factorization（PMF）conducted with high-resolution organic mass spectra dataset differentiated the organic aerosol into three components, including a hydrocarbon-like organic aerosol（HOA） and two oxygenated organic aerosols（SV-OOA and LV-OOA）, which on average accounted for 27.6%,28.8%, and 43.6% of the total organic mass, respectively. The relationship between the mass concentration of submicron particle species and wind further confirmed that all major fine particle species were influenced by both strong local emissions in the southeastern area of Xiamen and regional transport through the Taiwan Strait.

关键词： Submicron particle Chemical characterization Organic aerosol Source apportionment

Ca_v3.3-mediated endochondral ossification in a three-dimensional bioprinted Gel MA hydrogel

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Bio-Design and Manufacturing 2024年第6期7卷 983-999页

作者： Zhi Wang Xin Wang Yang huang junjun Yang Zu Wan Zhenlan Fu Xiaoyuan Gong Guangxing Chen Liu Yang Chongqing Key Laboratory of Precision Medicine in Joint Surgery Center for Joint SurgerySouthwest HospitalArmy Medical University(Third Military Medical University)Chongqing 400038China Department of Pharmacy and Laboratory Medicine Army Medical University(Third Military Medical University)Chongqing 400038China Key Laboratory of Biorheological Science and Technology Ministry of EducationCollege of BioengineeringChongqing UniversityChongqing 400044China

The growth plate(GP)is a crucial tissue involved in skeleton development via endochondral ossification(EO).The bone organoid is a potential research model capable of simulating the physiological function,spatial structure,and intercellular communication of native ***,mimicking the EO process remains a key challenge for bone organoid *** simulate this orderly mineralization process,we designed an in vitro sh Ca_(v)3.3 ATDC5-loaded gelatin methacryloyl(Gel MA)hydrogel model and evaluated its bioprintability for future organoid *** this paper,we report the first demonstration that the T-type voltage-dependent calcium channel(T-VDCC)subtype Ca_(v)3.3 is dominantly expressed in chondrocytes and is negatively correlated with the hypertrophic differentiation of chondrocytes during the EO ***,Ca_(v)3.3 knockdown chondrocytes loaded with the Gel MA hydrogel successfully captured the EO process and provide a bioink capable of constructing layered and orderly mineralized GP organoids in the *** results of this study could therefore provide a potential target for regulating the EO process and a novel strategy for simulating it in bone organoids.

关键词： Bone organoid Endochondral ossification T-type voltage-dependent calcium channel(T-VDCC) Ca_(v)3.3 3D bioprinting

Linguistic feature template integration for Chinese-Vietnamese neural machine translation

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Frontiers of Computer Science 2022年第4期16卷 223-225页

作者： Zhiqiang YU Yantuan XIAN Zhengtao YU Yuxin huang junjun GUO Faculty of Information Engineering and Automation Kunming University of Science and TechnologyKunming 650500China School of Mathematics and Computer Science Yunnan Minzu UniversityKunming 650500China Yunnan Key Laboratory of Artificial Intelligence Kunming University of Science and TechnologyKunming 650500China

1 Introduction and main contributions Template-based approaches have achieved significant progress in low-resource neural machine translation(NMT)recently[1],such as the efficient works,NMT-GTM[2],SoftPrototype[3],***,most previous works only retrieve target sentence as template to generate translation,neglecting the utilization of linguistic feature that contained in the source sentence and template.

关键词： translation template such

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Positron emission tomography study of the specificity of Waiguan (SJ 5) acupoint

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Neural Regeneration Research 2011年第18期6卷 1391-1397页

作者： Xinsheng Lai Chunzhi Tang Guifeng Zhang junjun Yang Gustav Wik Baoci Shan Yangjia Lu Yong huang Department of Acupuncture and Massage Guangzhou University of Traditional Chinese Medicine Guangzhou 510405 Guangdong Province China School of Traditional Chinese Medicine Southern Medical University Guangzhou 510515 Guangdong Province China Department of Clinical Medicine University of Bergen Sandviken Hospital Bergen 116011 Norway Institute of High Energy Physics Chinese Academy of Science Beijing 100049 China

Functional brain imaging studies of the specificity of acupoint stimulation have revealed that needling at particular acupoints can induce activation of corresponding brain areas, examined in physiological and pathological states. The present study examined Waiguan （SJ 5） as the acupoint of interest. We tested five conditions： a true needling at true acupoint group, a sham needling at true acupoint group, a true needling at sham acupoint group, a sham needling at sham acupoint group, and a healthy control group. We examined changes in glucose metabolism in different functional cortical regions to determine the specific brain activation elicited by acupuncture at Waiguan. The results revealed that true and sham acupuncture at the same acupoint activated different brain regions. In addition, applying acupuncture at a genuine acupoint and a neighboring sham acupoint activated different brain regions. These findings suggest that acupuncture at Waiguan causes activation in some brain regions.

关键词： acupoint specificity needling Waiguan (SJ 5) positron emission tomography cerebral function imaging

Acupuncture at Waiguan(SJ5) and sham points influences activation of functional brain areas of ischemic stroke patients: a functional magnetic resonance imaging study

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Neural Regeneration Research 2014年第3期9卷 293-300页

作者： Ji Qi Junqi Chen Yong huang Xinsheng Lai Chunzhi Tang junjun Yang Hua Chen Shanshan Qu School of Traditional Chinese Medicine Southern Medical University Department of Rehabilitation The Third Affiliated Hospital of Southern Medical University School of Acupuncture-moxibustion and Tuina Guangzhou University of Chinese Medicine School of Chinese Medicine Hong Kong Baptist University School of Biomedical Engineering Southern Medical University

Most studies addressing the specificity of meridians and acupuncture points have focused mainly on the different neural effects of acupuncture at different points in healthy individuals. This study examined the effects of acupuncture on brain function in a pathological context. Sixteen patients with ischemic stroke were randomly assigned to true point group （true acupuncture at right Waiguan （SJ5）） and sham point group （sham acupuncture）. Results of functional magnetic resonance imaging revealed activation in right parietal lobe （Brodmann areas 7 and 19）, the right temporal lobe （Brodmann area 39）, the right limbic lobe （Brodmann area 23） and bilateral oc-cipital lobes （Brodmann area 18）. Furthermore, inhibition of bilateral frontal lobes （Brodmann area 4, 6, and 45）, right parietal lobe （Brodmann areas 1 and 5） and left temporal lobe （Brodmann area 21 ） were observed in the true point group. Activation in the precuneus of right parietal lobe （Brodmann area 7） and inhibition of the left superior frontal gyrus （Brodmann area 10） was observed in the sham group. Compared with sham acupuncture, acupuncture at Waiguan in stroke patients inhibited Brodmann area 5 on the healthy side. Results indicated that the altered specificity of sensation-associated cortex （Brodmann area 5） is possibly associated with a central mechanism of acupuncture at Waiguan for stroke patients.

关键词： nerve regeneration acupuncture Waiguan (SJS) brain injury ischemic stroke function-al magnetic resonance imaging Brodmann area sham point 973 Program neural regeneration

Robust ultrathin and transparent AZO/Ag-SnOx/AZO on polyimide substrate for flexible thin film heater with temperature over 400℃

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Journal of Materials Science & Technology 2020年第13期47卷 156-162页

作者： Zhaozhao Wang Jia Li junjun Xu Jinhua huang Ye Yang Ruiqin Tan Guofei Chen Xingzhong Fang Yue Zhao Weijie Song School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Faculty of Information and Computer Science Ningbo UniversityNingbo 315211China Jiangsu Collaborative Innovation Center of Photovoltaic Science and Engineering Changzhou 213164China

We developed flexible and transparent thin film heaters(TFHs)with a structure of AZO/AgSnOx/AZO/polyimide(PI)which exhibited superior stability under operational *** and robust doped silver(Ag)films were produced by introducing a small amount of SnOx during the sputtering *** AZO/Ag-SnOx/AZO stacks showed the best figure of merit value of 139.9,which was higher than that of ITO counterpart(25.5)with the same *** addition,it exhibited excellent durability,which showed unaffected optical and electrical properties under the heat treatment of 500℃for 30 min in air,highly-accelerated tempe ratu re and humidity stress test(HAST)at 121℃and 97%RH for 36 h,10,000 times of scratching and 1500 times of inner and outer bending ***,the TFHs based on AZO/Ag-SnOx/AZO/PI achieved a high temperature of 438.8℃with response time in several seconds,which outperformed most previous *** robust high-temperature TFHs in this research hold promising commercial applications in flexible and high temperature occasions.

关键词： Ultrathin Ag films SnOx Doping Durability High temperature thin film heater

工程认证背景下“粉体工程”混合式教学模式改革与实践

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广东化工 2021年第21期48卷 243-244页

作者：桂成梅赵娣芳李宏林黄俊俊陈珍明李鹏巢湖学院化学与材料工程学院安徽巢湖238024 贺州学院材料与化工学院广西碳酸钙资源综合利用重点实验室广西贺州542899 合肥学院化学与材料工程系安徽合肥230601

《粉体工程》是无机非金属材料工程专业核心课程之一,在专业工程认证的背景下结合《粉体工程》的课程特点,以巢湖学院《粉体工程》课程的教学模式改革为例,提出基于OBE理念的《粉体工程》线上线下混合式教学改革思路与措施,从而提高《... 详细信息

《粉体工程》是无机非金属材料工程专业核心课程之一,在专业工程认证的背景下结合《粉体工程》的课程特点,以巢湖学院《粉体工程》课程的教学模式改革为例,提出基于OBE理念的《粉体工程》线上线下混合式教学改革思路与措施,从而提高《粉体工程》课程的教学效果,以此来促进无机非金属材料工程专业其他专业基础理论课程教学质量的提升。

关键词：工程认证粉体工程线上线下混合式教学 OBE理念教学改革

Acupoints combination correlates with activation of cerebral areas A functional MRI study

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Neural Regeneration Research 2011年第9期6卷 671-675页

作者： Xinsheng Lai Yong huang Chunzhi Tang junjun Yang Yanqi Zou Junxian Wu Yangjia Lu Renyong Lin Department of Meiridan Study School of Acupuncture and Massage Guangzhou University of Traditional Chinese Medicine Guangzhou 510405 Guangdong Province China Department of Acupuncture and Moxibustion School of Traditional Chinese Medicine Southern Medical University Guangzhou 510515 Guangdong Province China

Acupoint combination is a method used for acupoint treatment of patients. Traditionally, acupoints are matched along the meridian distribution, which is a common rule in clinical practice, but the underlying mechanism remains unclear. Cerebral scans with functional magnetic resonance imaging （fMRI） have been used in the study of acupuncture and acupoint specifically. In this study, fMRI was used to detect the activation of the brain areas under different acupoints, matched along different meridians, to elucidate the acupoint combination via a modern medical approach. Forty healthy volunteers were randomly divided into the following groups： Waiguan point （SJ 5）, Waiguan （SJ 5）＋ Zhigou （SJ 6）（2 acupoints come from the same meridian）, Waiguan （SJ 5）＋ Neiguan （PC 6）（2 acupoints come from 2 meridians with the relationship of interior-exterior）, Waiguan （SJ 5）＋ Yanglingquan （GB 34）（2 acupoints come from 2 meridians with the same name-Shaoyang Meridian）, and sham point groups （needling in different points on the right hand）. A real-time cerebral fMRI scan was simultaneously performed. The cerebral activation rate, and the number and strength of different regions of interest were compared among the groups. The fMRI cerebral imaging confirmed that there were some differences in the activation of cerebral areas by the needlings in SJ 5, and in combination with other acupoints. Needling at SJ 5 alone greatly activated the right cerebellum, while needling at both SJ 5 and different co-needling points activated different cerebral functional areas.

关键词： acupuncture Waiguan point acupoint combination cerebral functional imaging functional MRI

Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people A functional MRI study

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Neural Regeneration Research 2013年第3期8卷 226-232页

作者： Junqi Chen Yong huang Xinsheng Lai Chunzhi Tang junjun Yang Hua Chen Tongjun Zeng Junxian Wu Shanshan Qu College of Traditional Chinese Medicine Southern Medical University College of Acupuncture and Manipulation Guangzhou University of Chinese Medicine College of Biomedical Engineering Southern Medical University The First People's Hospital of Shunde Department of Acupuncture Shantou Central Hospital

In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan （TE5）. In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lobe, the mamiilary body, and the ventral posterolateral nucleus of the left hemisphere, and Broadmann areas 4, 6, 7, 18, 19 and 32 of the right hemisphere, but attenuated activation of Broadmann area 13, the hypothalamic inferior lobe, the posterior lobe of the tonsil of cerebellum, and the culmen of the anterior lobe of hypophysis, in the left hemisphere and Broadmann area 13 in the right hemisphere. In ischemic stroke subjects, a number of deactivated brain areas were enhanced, including Broadmann areas 6, 11,20, 22, 37, and 47, the culmen of the anterior lobe of hypophysis, alae lingulae cerebella, and the posterior lobe of the tonsil of cerebellum of the left hemisphere, and Broadmann areas 8, 37, 45 and 47, the culmen of the anterior lobe of hypophysis, pars tuberalis adenohypophyseos, inferior border of lentiform nucleus, lateral globus pallidus, inferior temporal gyrus, and the parahippocampal gyrus of the right hemisphere. These subjects also exhibited attenuation of a number of deactivated brain areas, including Broadmann area 7. These data suggest that acupuncture at Waiguan specifically alters brain function in regions associated with sensation, vision, and motion in ischemic stroke patients. By contrast, in normal individuals, acupuncture at Waiguan generally activates brain areas associated with insomnia and other functions.

关键词： neural regeneration acupuncture and moxibustion Waiguan (TE5) ischemic stroke specificity ofacupoints functional MRI cerebral function imaging acupuncture motion brain areas grants-supported paper photographs-containing paper neuroregeneration