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Ti_(3)C_(2)T_(x)-TiSe_(2) analogous heterostructure for flexible zinc ion battery

Journal of Materials Science & Technology 2023年第19期150卷 225-232页

作者： Li Wen junjie Shi Qixiang Zhang Fei Wang Siliang Wang Shaojun Zhang Qiang Wang Ke mao Fei Long Yihua Gao Center for Nanoscale Characterization&Devices(CNCD) School of Physics and Wuhan National Laboratory for Optoelectronics(WNLO)Huazhong University of Science and Technology(HUST)Wuhan 430074China Information Materials and Intelligent Sensing Laboratory of Anhui Province School of Integrated CircuitsAnhui UniversityHefei 230601China College of Materials Science and Engineering Guangxi Key Laboratory of Optical and Electronic Materials and DevicesGuilin University of TechnologyGuilin 541004China

Exploring zinc-free anode materials is one of the effective strategies to get the zinc dendrites problem of flexible zinc ion battery(ZIB)*** this work,an analogous heterostructure(AHS)is constructed from the excellent MXene(Ti_(3)C_(2)T_(x))and TiSe_(2) *** AHS not only possesses numerous diffu-sion paths and Zn^(2+)storage sites but also possesses a stable conductive network to accelerate charge transfer in the *** a collaborative advantage,electrochemical measurement results show that MXene/TiSe_(2) electrodes display an excellent specific capacity of 177.9 mAh g^(-1) at 0.10 A g^(-1) and a long-term cycling stability of 77.4%capacity retention after 400 *** computations further demon-strate the excellent performance of MXene/TiSe_(2) electrodes including desirable electronic conductivity and low Zn^(2+)migration *** assembled flexible ZIB not only delivers a good specific capacity of 42.2μAh cm^(-2) at 0.20 mA cm^(-2) and a competitive energy density of 37.4μWh cm^(-2) but also exhibits excellent flexibility and ***,after 400 cycles at 0.60 A g^(-1),flexible ZIB shows a capacity retention of 73.8%.This work gives a successful attempt to design 2D layered materials as Zn metal-free anode for flexible ZIB.

关键词： Flexible zinc ion battery Analogous heterostructure Zinc dendrite Zinc free metal anode MXene flakes TiSe_(2)nanosheets

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miRNAs targeting CYP6ER1 and CarE1 are involved in nitenpyram resistance in Nilaparvata lugens

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Insect Science 2022年第1期29卷 177-187页

作者： Kaikai mao Ruoheng Jin Zhijie Ren junjie Zhang Zhao Li Shun He Kangsheng Ma Hu Wan Jianhong Li Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhanChina

The evolution of nitenpyram resistance has been confirmed to be related to overexpression of two key metabolic enzyme genes, CYP6ER1 and CarE1, in Nilaparvata lugens, a highly destructive rice pest that causes substantial economic losses and has developed insecticide resistance. As microRNAs (miRNAs) are important post-transcriptional regulators of gene expression, whether they are involved in nitenpyram resistance is poorly understood in N. lugens. In this study, knockdown of key genes in the miRNA biogenesis pathway (Dicer1, Drosha, and Argonaute1) changed CYP6ER1 and CarE1 abundance, which confirmed the importance of miRNAs in nitenpyram resistance. Furthermore, global screening of miRNAs associated with nitenpyram resistance in N. lugens was performed, and a total of 42 known and 178 novel miRNAs were identified;of these, 57 were differentially expressed between the susceptible and resistant strains, and two (novel_85 and novel_191) were predicted to target CYP6ER1 and CarE1, respectively. Luciferase reporter assays demonstrated that novel_85 and novel_191 bind to the CYP6ER1 and CarE1 coding regions, respectively, and downregulate their expression. Moreover, modulating novel_85 and novel_191 expression by injection of miRNA inhibitors and mimics significantly altered N. lugens nitenpyram susceptibility. This is the first study to systematically screen and identify miRNAs associated with N. lugens nitenpyram resistance, and provides important information that can be used to develop new miRNA-based targets in insecticide resistance management.

关键词： CarE1 CYP6ER1 miRNAs Nilaparvata lugens nitenpyram resistance

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Overview of Research and Development for Anticancer Drugs

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Journal of Cancer Therapy 2016年第10期7卷 762-772页

作者： junjie Xu Wenwei mao Shanghai Jiao Tong University School of Medicine Shanghai China Lab of Microbial and Biochemical Pharmaceutical School of Pharmacy Shanghai Jiao Tong University Shanghai China Engineering Research Center of Cell and Therapeutic Antibody Ministry of Education School of Pharmacy Shanghai Jiao Tong University Shanghai China

Anticancer drugs research and development have been the largest market area in the pharmaceutical industry in terms of the number of project, clinical trials and spending. In the last 10 - 30 years, targeting therapy for cancers has been developed and achieved enormous clinical effectiveness by transforming some previously deadly malignancies into chronically manageable conditions, but cure problem still remains. This mini review outlined the current status of anticancer drugs development and hinted the opinions of how to further increase the accuracy and efficacy of discovery for cancer treatment.

关键词： Anticancer Drugs Research and Development Target Therapy Phenotype Targeting Anti-Tumor Immunity

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Actual evapotranspiration of subalpine meadows in the Qilian Mountains, Northwest China

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Journal of Arid Land 2019年第3期11卷 371-384页

作者： GAO Yunfei ZHAO Chuanyan Muhammad W ASHIQ WANG Qingtao RONG Zhanlei LIU junjie mao Yahua GUO Zhaoxia WANG Wenbin State Key Laboratory of Grassland and Agro-Ecosystems School of Life SciencesLanzhou UniversityLanzhou 730000China State Key Laboratory of Grassland and Agro-Ecosystems College of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhou 730000China Ministry of Natural Resources and Forestry Timmins District5520 Hwy 101 ESouth PorcupineONPON 1 HOCanada

As a main component in water balance,evapotranspiration(ET)is of great importance for water saving,especially in arid and semi-arid *** this study,the FAO(Food and Agriculture Organization)Penman-Monteith model was used to estimate the magnitude and temporal dynamics of reference evapotranspiration(ET0)in 2014 in subalpine meadows of the Qilian Mountains,Northwest ***,actual ET(ETc)was also investigated by the eddy covariance(EC)*** indicated that ETc estimated by the EC System was 583 mm,lower than ET0(923 mm)estimated by the FAO Penman-Monteith model in ***,ET0 began to increase in March and reached the peak value in August and then declined in September,however,ETc began to increase from April and reached the peak value in July,and then declined in *** ETc and ET0 values during the growing season(from May to September)were 441 and 666 mm,respectively,which accounted for 75.73%of annual cumulative ETc and 72.34%of annual cumulative ET0,respectively.A crop coefficient(kc)was also estimated for calculating the ETc,and average value of kc during the growing season was 0.81(ranging from 0.45 to 1.16).Air temperature(Ta),wind speed(u),net radiation(Rn)and soil temperature(Ts)at the depth of 5 cm and aboveground biomass were critical factors for affecting kc,furthermore,a daily empirical kc equation including these main driving factors was *** result demonstrated that the ETc value estimated by the data of kc and ET0 was validated and consistent with the growing season data in 2015 and 2016.

关键词： actual evapotranspiration reference evapotranspiration crop coefficient meteorological factors biotic factors

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Leaf gas exchange and photosynthesis curves of Elymus nutans and Potentilla anserina under fencing and grazing conditions in the Qilian Mountains, Northwest China

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Journal of Arid Land 2019年第3期11卷 431-445页

作者： LIU junjie WANG Xiaoping GAO Yunfei RONG Zhanlei ZHANG Guangde WANG Wenbin GE Lijuan mao Yahua GUO Zhaoxia ZHAO Chuanyan State Key Laboratory of Grassland Agro-ecosystems School of Life SciencesLanzhou UniversityLanzhou 730000China Institute of Arid Meteorology China Meteorological AdministrationLanzhou 730020China

Potentilla anserina *** Elymus nutans *** dominant species in the subalpine meadows of *** is one of the most important factors that influence community structure and productivity of subalpine *** how grazing changes photosynthetic capability is essential for preservation and restoration of ***,information about the effects of grazing on photosynthetic capability remains *** were conducted in fencing and grazing areas in the Qilian Mountains,Northwest *** leaf gas exchange and photosynthetic curves of *** and *** were measured at different growth *** showed that grazing decreased the values of leaf gas exchange parameters,such as net photosynthetic rate,stomatal conductance,transpiration rate,and intercellular CO2 concentration of *** and *** addition,grazing decreased the values of net photosynthetic rate-photosynthetically active radiation(PN-PAR)curve parameters,such as light-saturated net photosynthetic rate,apparent quantum efficiency,light compensation point,light saturation point,and dark respiration *** results demonstrated that grazing was the primary limiting factor for photosynthesis of dominant grassland species in the study area.

关键词： grazing diurnal variation gas exchange Potentilla anserina Elymus nutans photosynthetic capacity

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湖北黄石新型冠状病毒肺炎流行模式及防控效果研究

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南通大学学报（医学版） 2022年第3期42卷 219-224页

作者：於成俊赵克提袁建明朱清毛俊杰胡明霞张彬孙怡华秦刚南通大学附属医院感染科南通226001 湖北省黄石市疾病预防控制中心江苏省南通市疾病预防控制中心南通大学药学院南通大学公共卫生学院南通大学医学院

目的:了解2020年湖北省黄石市新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)疫情的流行病学特征,并评估防控效果。方法:收集2020年1—3月黄石市COVID-19病例的个案信息及不同时间的防控措施,估算关键事件发生的时间间隔、潜伏... 详细信息

目的:了解2020年湖北省黄石市新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)疫情的流行病学特征,并评估防控效果。方法:收集2020年1—3月黄石市COVID-19病例的个案信息及不同时间的防控措施,估算关键事件发生的时间间隔、潜伏期(incubation period, IP)、倍增时间(doubling time, DT)及序列间隔(serial interval, SI),采用指数增长法(exponential growth method, EGR)估算再生数。结果:黄石市COVID-19感染者共计1 065例,其中发病人数1 015例,病死率为3.74%(38/1 015),每日新增发病人数峰值出现在“封城”后第9天。黄石市平均IP为4.6 d,平均SI为6.3,平均DT为2.3 d,从“起飞点”到达DT6为38 d,而武汉市仅用了9 d。2020年1月23日前基本再生数为4.80,1月24—30日和1月31日—2月25日的有效再生数分别为1.12和0.19。结论:基于流行病学调查和传播动力学模型分析,黄石市的早期非药物性干预措施改变了COVID-19疫情流行模式,实现“缓疫压峰”效果。

关键词：新型冠状病毒肺炎潜伏期倍增时间序列间隔基本再生数黄石市

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Modified non-rectangular hyperbola equation with plant height for photosynthetic light-response curves of Potentilla anserina and Elymus nutans at various growth phases in the Heihe River Basin, Northwest China

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Journal of Arid Land 2019年第5期11卷 764-773页

作者： LIU junjie WANG Xiaoping RONG Zhanlei GAO Yunfei ZHANG Guangde WANGWenbin GE Lijuan mao Yahua GUO Zhaoxia WANG Qingtao ZHAO Chuanyan State Key Laboratory of Grassland Agro-ecosystems School of Life SciencesLanzhou UniversityLanzhou 730000China Institute of Arid Meteorology China Meteorological AdministrationLanzhou 730020China College of landscape and Ecological Engineering Hebei University of EngineeringHandan 056000China

The non-rectangular hyperbola(NRH)equation is the most popular method that plots the photosynthetic light-response(PLR)curve and helps to identify plant photosynthetic ***,the PLR curve can't be plotted well by the NRH equation at different plant growth phases due to the variations of plant ***,plant physiological parameters have been considered into the NRH equation to establish the modified NRH equation,but plant height(H),an important parameter in plant growth phases,is not taken into *** this study,H was incorporated into the NRH equation to establish the modified NRH equation,which could be used to estimate photosynthetic capability of herbage at different growth *** explore photosynthetic capability of herbage,we selected the dominant herbage species Potentilla anserina *** Elymus nutans *** the Heihe River Basin,Northwest China as the research ***,twenty-four PLR curves and H at different growth phases were measured during the growing season in *** showed that the maximum net photosynthetic rate and the initial slope of PLR curve linearly increased with *** modified NRH equation,which is established by introducing H and an H-based adjustment factor into the NRH equation,described better the PLR curves of *** and *** than the original *** results may provide an effective method to estimate the net primary productivity of grasslands in the study area.

关键词： plant height modified non-rectangular hyperbola equation Potentilla anserina Elymus nutans photosynthetic light-response curve Qilian Mountains

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定点测距分级在男性雄激素性脱发中的适用性研究

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中华整形外科杂志 2023年第2期39卷 125-133页

作者：戚吉妮蒋宙男程含皛侯觉屠静怡周玥徐伟力赵钧周圳滔周易毛俊杰钱锡飞范崇祥张菊芳吕中法浙江中医药大学第四临床医学院浙江大学医学院附属杭州市第一人民医院杭州310006 浙江大学医学院附属杭州市第一人民医院整形外科杭州310006 解放军联勤保障部队第九○三医院烧伤整形科杭州310013 浙江大学医学院附属杭州市第一人民医院城北院区整形外科杭州310003 杭州市萧山区第一人民医院整形外科杭州311200 杭州市第九人民医院医疗美容科杭州310000 浙江中医药大学第一临床医学院杭州310053 浙江大学医学院附属第二医院皮肤科杭州310009

目的探讨定点测距分级在评估男性雄激素性脱发严重程度中的适用性。方法 2019年6至12月于杭州市第一人民医院脱发专科门诊根据定点测距分级及BASP(basic and specific)分级对诊断明确的中国男性雄激素性脱发患者进行评估。定点测距分级... 详细信息

目的探讨定点测距分级在评估男性雄激素性脱发严重程度中的适用性。方法 2019年6至12月于杭州市第一人民医院脱发专科门诊根据定点测距分级及BASP(basic and specific)分级对诊断明确的中国男性雄激素性脱发患者进行评估。定点测距分级基于患者毛发的测量数据进行评级,通过测量前发际线定点至眉水平线的距离、发旋中心的最长脱发半径,评估患者额(F)、颞(M)、顶(V)部毛发退缩情况,将各区域脱发情况由轻到重评为0~3级,最终脱发分级表示为FnMnVn形式(如F1M2V0)。以F、M、V中最高的脱发等级作为患者整体脱发分级。采用SPSS 25.0软件统计分析患者一般资料,采用Kappa检验评估定点测距分级与BASP分级结果间的一致性;通过3位脱发专科医生评级的重复率检验定点测距分级的重复性;3位脱发专科医生中2位及以上有相同评价的患者,将该评价结果视作标准结果,通过2位临时培训的普通医生的分级结果与标准结果的一致率检验定点测距分级的易用性。结果共纳入150例男性患者,年龄(32.8±7.9)岁(19~58岁),其中24~35岁者99例,占66.00%,可以观察到患者发病年龄偏早。经定点测距分级评估,150例患者中轻度脱发的人数最多[65例(43.33%)],其次为重度脱发[58例(38.67%)],与BASP分级所得结果的一致性中等(κ=0.573,P<0.001)。3位经验丰富的脱发专科医生通过定点测距分级对150例患者进行评估的结果显示,额、颞、顶部分级结果的重复率分别为98.00%(147/150)、97.33%(146/150)和96.00%(144/150),最终脱发分级的重复率为92.00%(138/150),整体脱发分级的重复率为98.00%(147/150)。2名临时培训的普通医生的整体脱发分级结果与标准结果的一致率分别为95.92%(141/147)与96.60%(142/147),且除其中1位普通医生在最终分级方面与标准结果的一致率为89.86%(124/138)外,其余结果一致率均高于90.00%。结论定点测距分级是一种针对中国男性雄激素性脱发患者设计、基于客观测量数据的可重复性高、易于学习使用的分级方法。

关键词：脱发男性雄激素性脱发脱发分级脱发诊断定点测距

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An Air‑Rechargeable Zn Battery Enabled by Organic–Inorganic Hybrid Cathode

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Nano-Micro Letters 2023年第4期15卷 138-152页

作者： junjie Shi Ke mao Qixiang Zhang Zunyu Liu Fei Long Li Wen Yixin Hou Xinliang Li Yanan Ma Yang Yue Luying Li Chunyi Zhi Yihua Gao Wuhan National Laboratory for Optoelectronics(WNLO)and School of Physics Center for Nanoscale Characterization&Devices(CNCD)Huazhong University of Science and Technology(HUST)Wuhan 430074People’s Republic of China Guangxi Key Laboratory of Optical and Electronic Materials and Devices College of Materials Science and EngineeringGuilin University of TechnologyGuilin 541004People’s Republic of China Hong Kong Center for Cerebro-Cardiovascular Health Engineering Hong Kong SAR 999077People’s Republic of China Hubei Key Laboratory of Critical Materials of New Energy Vehicles and School of Mathematics Physics and Optoelectronic EngineeringHubei University of Automotive TechnologyShiyan 442002People’s Republic of China Information Materials and Intelligent Sensing Laboratory of Anhui Province Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of EducationInstitutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601People’s Republic of China

Self-charging power systems collecting energy harvesting technology and batteries are attracting extensive *** solve the disadvantages of the traditional integrated system,such as highly dependent on energy supply and complex structure,an airrechargeable Zn battery based on MoS_(2)/PANI cathode is *** from the excellent conductivity desolvation shield of PANI,the MoS_(2)/PANI cathode exhibits ultra-high capacity(304.98 mAh g^(−1) in N_(2) and 351.25 mAh g^(−1) in air).In particular,this battery has the ability to collect,convert and store energy simultaneously by an airrechargeable process of the spontaneous redox reaction between the discharged cathode and O2 from *** air-rechargeable Zn batteries display a high open-circuit voltage(1.15 V),an unforgettable discharge capacity(316.09 mAh g^(−1) and the air-rechargeable depth is 89.99%)and good air-recharging stability(291.22 mAh g^(−1) after 50 air recharging/galvanostatic current discharge cycle).Most importantly,both our quasi-solid zinc ion batteries and batteries modules have excellent performance and *** work will provide a promising research direction for the material design and device assembly of the next-generation self-powered system.

关键词： Air-rechargeable MoS_(2)/PANI Cathode Desolvation shield Energy storage mechanism Zn batteries module

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Research on the Driving Forces and Network Organization of Urban Express Joint Distribution

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China City Planning Review 2021年第2期30卷 52-61页

作者： Xu junjie Cao Xi Li Min(Translated) mao Qizhi(Proofread) School of Economics and Management Anqing Normal UniversityAnqingP.R.China 不详

In a context where express delivery service is indispensable in urban production and life in China,urban express joint distribution will help reduce the negative impact of logistics activities on urban traffic and environment,and eventually promote the coordinated development of the express delivery industry and the *** paper summarizes the background of urban express joint distribution based on its four driving forces:saving resources,green development,traffic avoidance,and public *** it establishes a network structure model of urban express joint distribution based on systems thinking,elaborates the functional orientations of the four layers in the model–the distribution layer,the feeder transport layer,the terminal station layer,and the collection and delivery layer,and discusses the implementation ideas of joint distribution at all ***,it puts forward four suggestions for promoting the joint distribution:improving inter-departmental coordination mechanism,maintaining a diversified distribution pattern,promoting in-depth cooperation among companies,and practicing a high-tech development path.

关键词： urban logistics joint distribution express delivery industry package locker network organization

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