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Probing non-polarizable liquid/liquid interfaces using scanning ion conductance microscopy

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Science China Chemistry 2020年第3期63卷 411-418页

作者： Yaxiong Gu Ye Chen Yifan Dong junjie liu Xianhao Zhang Mingzhi Li Yuanhua Shao Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

The study of microscopic structure of a liquid/liquid interface is of fundamental importance due to its close relation to the thermodynamics and kinetics of interfacial charge transfer *** this article,the microscopic structure of a non-polarizable water/nitrobenzene(W/NB)interface was evaluated by scanning ion conductance microscope(SICM).Using SICM with a nanometer-sized quartz pipette filled with an electrolyte solution as the probe,the thickness of this type of W/NB interface could be measured at sub-nanometer scale,based on the continuous change of ionic current from one phase to another *** effects for thicknesses of the non-polarizable W/NB interfaces with different electrolyte concentrations,the Galvani potentials at the interface and the applied potentials on the probe were measured and systematically *** experimental setups,that is an organic phase up and an aqueous down,and a reverse version,were employed to acquire the approach *** data were compared with those of an ideal polarizable interface under the similar experimental conditions,and several characteristics of non-polarizable interfaces were *** thickness of a non-polarizable interface increases with the decrease of electrolyte concentration and the increase of applied potential,which is similar to the situation of a polarizable liquid/liquid *** also find that the Galvani potential across a non-polarizable interface can also influence the interfacial thickness,this phenomenon is difficult to observe when using polarizable *** importantly,by the comparison of two kinds of liquid/liquid interfaces,we experimentally proved that much more excess ions are gathered in the space charge layer of non-polarizable interfaces than in that of polarizable *** results are consistent with the predictions of molecular dynamic simulations and X-ray reflectivity measurements.

关键词： micro/nano pipettes scanning ion conductance microscopy microstructure of a non-polarizable liquid/liquid interface

基于发生层的均腐土理化性质和元素生态化学计量特征分析

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土壤与作物 2024年第3期13卷 255-268页

作者：刘株秀刘俊杰焦峰姚钦王光华中国科学院东北地理与农业生态研究所黑土地保护与利用全国重点实验室黑龙江哈尔滨150081 黑龙江八一农垦大学农学院黑龙江大庆163319

为明确土壤剖面理化性状及元素生态化学计量的变化规律,从而为认识土壤形成机制和保护土壤资源提供科学依据,本研究以黑龙江省干润和湿润均腐土亚纲为研究对象,基于发生层采集土壤剖面样品,对其理化性状及元素生态化学计量进行了比较分... 详细信息

为明确土壤剖面理化性状及元素生态化学计量的变化规律,从而为认识土壤形成机制和保护土壤资源提供科学依据,本研究以黑龙江省干润和湿润均腐土亚纲为研究对象,基于发生层采集土壤剖面样品,对其理化性状及元素生态化学计量进行了比较分析。结果表明,从A层到C层,均腐土的有机碳(SOC)、全氮(TN)、全磷(TP)、铵态氮(NH4+-N)、速效磷(AP)和砂粒含量以及土壤颗粒表面积和体积平均径(SMD和VMD)逐渐降低;相反,土壤pH、黏粒和粉粒含量则明显升高。研究发现不同土系均腐土C层(母质层)显示出了比Ah层(腐殖质层)更大的土壤异质性,并且湿润均腐土理化性质沿着剖面的垂直变化程度比干润均腐土更大。此外,元素生态化学计量分析发现,均腐土C∶N、C∶P和N∶P随着发生层深度的增加而明显降低,说明深层土壤养分循环过程受到碳和氮限制增强。

关键词：均腐土发生层垂直分布土壤性质生态计量比

基于HACCP风险评估的制药洁净空调系统设计思路探讨

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暖通空调 2024年第6期54卷 21-28页

作者：孟晗刘俊杰王荣赵雅楠天津大学“室内空气环境质量控制”天津市重点实验室天津

对标ISO 14644洁净室及相关受控环境系列标准,2021年我国洁净室行业的GB/T 25915系列标准也相应更新。本文对比分析了我国新旧版本GB/T 25915第1部分和第2部分关于洁净室及相关受控环境的标准变化,针对新标准中提出的风险评估要求,结合... 详细信息

对标ISO 14644洁净室及相关受控环境系列标准,2021年我国洁净室行业的GB/T 25915系列标准也相应更新。本文对比分析了我国新旧版本GB/T 25915第1部分和第2部分关于洁净室及相关受控环境的标准变化,针对新标准中提出的风险评估要求,结合制药厂房洁净空调系统设计经验,将危害分析临界控制点(HACCP)的风险评估方法应用于制药洁净空调系统设计。根据风险评估结果总结了洁净空调系统的设计流程,重点以洁净空调系统设计风量为例,提出了在设计阶段预留基于粒子浓度的风量控制模块,在保证洁净室污染风险可控条件下为洁净空调系统节能设计提供一个新思路。

关键词：风险评估危害分析临界控制点制药厂房洁净空调系统 ISO 14644 GB/T 25915

综合护理对胃癌手术患者术后疼痛、负面情绪及并发症的影响

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临床医学工程 2024年第6期31卷 751-752页

作者：刘俊杰贾如珍韩伟娜漯河市中医院手术室河南漯河462000

目的分析综合护理对胃癌手术患者术后疼痛、负面情绪、并发症的影响。方法80例胃癌患者随机分为两组各40例。术后,综合护理组给予综合护理,常规护理组给予常规护理。比较两组的疼痛程度、负面情绪及并发症。结果术后1 d、2d、3 d,综合... 详细信息

目的分析综合护理对胃癌手术患者术后疼痛、负面情绪、并发症的影响。方法80例胃癌患者随机分为两组各40例。术后,综合护理组给予综合护理,常规护理组给予常规护理。比较两组的疼痛程度、负面情绪及并发症。结果术后1 d、2d、3 d,综合护理组的VAS评分均显著低于常规护理组(P<0.05)。护理后,综合护理组的HADS-A评分、HADS-D评分、并发症总发生率均显著低于常规护理组(P<0.05)。结论综合护理可缓解胃癌术后患者的疼痛及负面情绪,降低并发症发生风险。

关键词：胃癌手术综合护理疼痛负面情绪并发症

Liaofu Luo:A pure scientist of theoretical biophysics

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Quantitative Biology 2022年第3期10卷 221-223页

作者： Lirong Zhang junjie liu School of Physical Science and Technology Inner Mongolia UniversityHohhot 010021China

Liaofu Luo is a senior Professor of Physics at the Inner Mongolia University,*** was born in Shanghai in September *** his graduation with honors from the Department of Physics of Peking University,in 1958,Professor Luo developed his career at the Inner Mongolia University,where he has been working in theoretical physics and interdisciplinary sciences for more than 60 *** has been the author of more than 400 scientific articles in particle physics and biophysics and initiated a research group focused on bioinformatics ***,at the age of 85,Luo is still active at the forefront of the scientific research of his *** says that there is nothing he would rather do.

关键词： nothing initiated honor

Boosting 5-ALA-based photodynamic therapy by a liposomal nanomedicine through intracellular iron ion regulation

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Acta Pharmaceutica Sinica B 2021年第5期11卷 1329-1340页

作者： Airong Li Chenglin Liang Lihua Xu Yiyang Wang Wei liu Kaixiang Zhang junjie liu Jinjin Shi Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases School of Pharmaceutical SciencesZhengzhou UniversityZhengzhou 450001China

5-Aminolevulinic acid(5-ALA)has been approved for clinical photodynamic therapy(PDT)due to its negligible photosensitive ***,the curative effect of 5-ALA is restricted by intracellular biotransformation inactivation of 5-ALA and potential DNA repair of tumor *** by the crucial function of iron ions in 5-ALA transformation and DNA repair,a liposomal nanomedicine(MFLs@5-ALA/DFO)with intracellular iron ion regulation property was developed for boosting the PDT of 5-ALA,which was prepared by co-encapsulating 5-ALA and DFO(deferoxamine,a special iron chelator)into the membrane fusion liposomes(MFLs).MFLs@5-ALA/DFO showed an improved pharmaceutical behavior and rapidly fused with tumor cell membrane for 5-ALA and DFO ***@5-ALA/DFO could efficiently reduce iron ion,thus blocking the biotransformation of photosensitive protoporphyrin IX(Pp IX)to heme,realizing significant accumulation of ***,the activity of DNA repair enzyme was also inhibited with the reduction of iron ion,resulting in the aggravated DNA damage in tumor *** findings showed MFLs@5-ALA/DFO had potential to be applied for enhanced PDT of 5-ALA.

关键词： 5-Aminolevulinic acid Biotransformation interference Iron ion regulation DNA repair inhibition ALKBH2 Membrane fusion liposomes Photodynamic therapy Drug delivery

Three-dimensional anisotropic induced polarization modeling using finite element method

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Earthquake Research Advances 2021年第S1期1卷 49-52页

作者： junjie liu Xiaoping Wu School of Earth and Space sciences University of Science and Technology of ChinaHefeiChina

With the development of geophysical exploration technology,the anisotropy of underground media has got more and more *** present,there are few studies on the anisotropy of the induced polarization *** article explores the effect of anisotropy on the underground media of the induced polarization method under three-dimensional complex *** research work transforms the underground electric field control equation into a variational problem,and use the unstructured finite element method to construct a large linear equation system for solving electric *** the sparse matrix compression technique and symmetric successive over-relaxation preconditioned conjugate gradient algorithm(SSOR-PCG)to solve the equation ***,the article uses the classic central gradient array method to obtain the forward apparent polarizability *** calculation results of the model find that different anisotropic conditions will significantly affect the forward results which show a strong directional correlation,revealing the importance of considering anisotropy in practical work.

关键词： Three-dimensional anisotropic finite element method

人文关怀护理用于甲状腺癌手术患者的效果观察

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临床医学工程 2024年第3期31卷 357-358页

作者：张丽霞包亚冲刘俊杰漯河市中医院手术室河南漯河462000

目的分析人文关怀护理对甲状腺癌手术患者的效果。方法选择2019年1月至2023年1月在我院手术的甲状腺癌患者80例,随机分为常规组(40例,常规护理)和研究组(40例,常规护理+人文关怀护理),比较两组患者的抑郁、焦虑情绪、术后疼痛及并发... 详细信息

目的分析人文关怀护理对甲状腺癌手术患者的效果。方法选择2019年1月至2023年1月在我院手术的甲状腺癌患者80例,随机分为常规组(40例,常规护理)和研究组(40例,常规护理+人文关怀护理),比较两组患者的抑郁、焦虑情绪、术后疼痛及并发症。结果干预后,研究组HAMD、 HAMA评分低于常规组(P <0.05)。研究组术后6 h、 12 h、 24 h的VAS评分均低于常规组(P <0.05)。研究组并发症发生率低于常规组(P <0.05)。结论人文关怀护理可显著改善甲状腺癌手术患者的不良情绪,减轻术后疼痛,降并发症发生率。

关键词：人文关怀护理甲状腺癌效果

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基于非接触式的三维重建技术综述

机电工程技术 2024年第5期53卷 1-5,42页

作者：李柏雄刘俊杰刘建青程霖葛平淑大连民族大学机电工程学院辽宁大连116600 大连日佳电子有限公司研发部辽宁大连116600

三维重建技术作为获取研究对象空间信息的主要途径,在计算机视觉和计算机图形学领域引起广泛关注,在工业制造、虚拟现实与增强现实、医疗等领域发挥重要作用,呈现出极高的研究价值。为了全面了解三维重建技术的多样方法适应性,聚焦于基... 详细信息

三维重建技术作为获取研究对象空间信息的主要途径,在计算机视觉和计算机图形学领域引起广泛关注,在工业制造、虚拟现实与增强现实、医疗等领域发挥重要作用,呈现出极高的研究价值。为了全面了解三维重建技术的多样方法适应性,聚焦于基于非接触式的三维重建技术的探讨,其中包括飞行时间法、基于三角测距的结构光三维重建、单目视觉、双目视觉、多目视觉的三维重建方法。对各种方法的基本理论进行分析,归纳其应用场景并对未来研究方向做出展望。

关键词：三维重建图像处理非接触式基本理论

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