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Origin of the giant persistent photoconductivity in LaAlO_(3)/SrTiO_(3)heterostructures probed by noise spectroscopy

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Journal of Materials Science & Technology 2023年第6期137卷 152-158页

作者： Kitae Eom jung-woo lee Gyeongmo Yang Youngmin Kim Jaeyoung Jeon Jieun Yeon Hyungwoo lee School of Advanced Materials Science and Engineering Sungkyunkwan University(SKKU)Suwon 16419South Korea KIURI Institute Yonsei UniversitySeoul 03722South Korea Department of Physics Ajou UniversitySuwon 16499South Korea Department of Energy Systems Research Ajou UniversitySuwon 16499South Korea

LaAlO_(3)/SrTiO_(3)(LAO/STO)heterostructures have shown a strong persistent photoconductivity(PPC)at room *** abnormally strong PPC has attracted immense research interest due to its possible applications in optically-tunable electronic *** its promise,the fundamental understanding of the PPC in the LAO/STO heterostructures is still ***,we report that the giant PPC origi-nates from the photo-induced valence change in oxygen vacancies near the LAO/STO *** spec-tral analysis of the photocurrent and the model-fitting study consistently show that the ionized oxygen vacancies near the interface are neutralized during the electron relaxation *** hinder the complete relaxation of the photoexcited electrons by the deeply-located oxygen vacancies and result in the strong *** change in the ionization state distribution of the oxygen vacancies is probed by the per-sistent noise behavior at the frequency between 1 kHz and 20 kHz *** results provide insight into the role of oxygen vacancies in influencing the internal charge distribution and triggering the PPC phenomena in complex oxide heterostructures.

关键词： Persistent photoconductivity LaAlO_(3)/SrTiO_(3)heterostructures Two-dimensional electron gases Oxygen vacancies Low-frequency noise Spectral analyses

^(27)Al MAS-NMR study of inorganic polymer formation at ambient temperature

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 182-187页

作者： Sang-wook AHN Hee-Soo lee Wan-Hee YANG jung-woo lee Young-Keun JEONG National Core Research Center for Hybrid Materials Solution Pusan National University School of Material Science and Engineering Pusan National University INTChem Co. Ltd.

Inorganic polymers are a novel class of materials formed by the polymerization of silicon, aluminium and oxygen species to form an amorphous three-dimensional framework structure. The basis of this process is the alkaline solutions to induce a certain amount of Si and AI atoms to dissolve from a feedstock such as aluminosilicate. A study of 27A1 MAS-NMR was carried out in an attempt to understand the reaction mechanism of the inorganic polymerization at ambient temperature. Scanning electron microscopy （SEM） and X-ray diflYactometry （XRD） were also employed to establish the composition and microstructure of the inorganic polymerization. Specimens were prepared with different A1/Si mole ratios from the starting materials. The higher the AI content, the more sufficient the AI atoms that can combine with SiO4, and the longer the reaction time, the more the bonded Si--O--A1--O polymer structure, and then the higher the A1 content, the fewer the octahedral A1 with a uniform Si--O--A1--O structure in four directions, because four AI atoms are combined with SiO4, resulting in a uniform Si--O--AI--O structure in four directions. The results show that they have an amorphous microstructure.

关键词： inorganic polymer amorphous tetrahedral

Work up for the clopidogrel hypersensitivity that led to recognising the undi- agnosed myelodysplastic syndrome

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Journal of Geriatric Cardiology 2016年第3期13卷 274-276页

作者： Yoo Sang Baek jung woo lee Jiehyun Jeon Department of Dermatology College of Medicine Korea University Seoul South Korea

Antiplatelet therapy with clopidogrel is widely used as a preventive strategy in patients with acute coronary syn- drome, particularly after stent *** mani- festations of clopidogrel hypersensitivity reaction have been reported including cutaneous,and hematologic symp- toms[31 as well as fatal reactions including thrombotic throm- bocytopenic purpura （TTP）.

关键词： Clopidogrel Hypersensitivity Myelodysplastic syndrome

Over 100-THz bandwidth selective difference frequency generation at LaAlO_(3)/SrTiO_(3) nanojunctions

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Light(Science & Applications) 2019年第1期8卷 968-974页

作者： Lu Chen Erin Sutton Hyungwoo lee jung-woo lee Jianan Li Chang-Beom Eom Patrick Irvin Jeremy Levy Department of Physics and Astronomy University of PittsburghPittsburghPA 15260USA Pittsburgh Quantum Institute PittsburghPA 15260USA Department of Materials Science and Engineering University of Wisconsin-MadisonMadisonWA 53706USA

The ability to combine continuously tunable narrow-band terahertz(THz)generation that can access both the farinfrared and mid-infrared regimes with nanometer-scale spatial resolution is highly promising for identifying underlying light-matter interactions and realizing selective control of rotational or vibrational resonances in nanoparticles or ***,we report selective difference frequency generation with over 100 THz bandwidth via femtosecond optical pulse *** THz emission is generated at nanoscale junctions at the interface of LaAlO_(3)/SrTiO_(3)(LAO/STO)that is defined by conductive atomic force microscope lithography,with the potential to perform THz spectroscopy on individual nanoparticles or *** simulation of the time-domain signal facilitates the identification of components that contribute to the THz *** ultra-wide-bandwidth tunable nanoscale coherent THz source transforms the LAO/STO interface into a promising platform for integrated lab-on-chip optoelectronic devices with various functionalities.

关键词： tunable lithography selective

Minimally invasive vs open pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors

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World Journal of Gastrointestinal Oncology 2020年第10期12卷 1133-1145页

作者： Juwan Kim Ho Kyoung Hwang woo jung lee Chang Moo Kang Department of Surgery Yonsei University College of MedicineSeoul 03722South Korea

BACKGROUND The mainstay of treating nonfunctioning-pancreatic neuroendocrine tumors(NFPNETs)is surgical ***,minimally invasive approaches to pancreatic resection for treating NF-PNETs are not widely accepted,and the longterm oncological outcomes of such approaches remain *** To determine the short-and long-term outcomes of minimally invasive pancreatic resection conducted in patients with *** Prospective databases from Severance Hospital were searched for 110 patients who underwent curative resection for NF-PNETs between January 2003 and August *** The proportion of minimally invasive surgery(MIS)procedures performed for NF-PNET increased to more than 75%after *** was no significant difference in post-operative complications(P=0.654),including pancreatic fistula(P=0.890)and delayed gastric emptying(P=0.652),between MIS and open *** statistically significant difference was found in disease-free survival between the open approach group and the MIS group(median follow-up period,28.1 mo;P=0.428).In addition,the surgical approach(MIS vs open)was not found to be an independent prognostic factor in treating NF-PNET patients[Exp(β)=1.062;P=0.929].CONCLUSION Regardless of the type of surgery,a minimally invasive approach can be safe and feasible for select NF-PNET patients.

关键词： Nonfunctioning-pancreas neuroendocrine tumor Pancreatic neuroendocrine tumor Minimally invasive surgery Oncologic outcome Laparoscopic pancreaticoduodenectomy Laparoscopic distal pancreatectomy

Preoperative defining system for pancreatic head cancer considering surgical resection

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World Journal of Gastroenterology 2016年第26期22卷 6076-6082页

作者： Seok Jeong Yang Ho Kyoung Hwang Chang Moo Kang woo jung lee Department of Surgery Ulsan University Hospital University of Ulsan College of Medicine Department of Hepatobiliary and Pancreatic Surgery Yonsei University College of Medicine Pancreaticobiliary Cancer Clinic Yonsei Cancer Center Institute of Gastroenterology Yonsei Severance Hospital

AIM: To provide appropriate treatment, it is crucial to share the clinical status of pancreas head cancer among multidisciplinary treatment ***: A retrospective analysis of the medical records of 113 patients who underwent surgery for pancreas head cancer from January 2008 to December 2012 was performed. We developed preoperative defining system of pancreatic head cancer by describing “resectability - tumor location - vascular relationship - adjacent organ involvement - preoperative CA19-9 (initial bilirubin level) - vascular anomaly”. The oncologic correlations with this reporting system were ***: Among 113 patients, there were 75 patients (66.4%) with resectable, 34 patients (30.1%) with borderline resectable, and 4 patients (3.5%) with locally advanced pancreatic cancer. Mean disease-free survival was 24.8 mo (95%CI: 19.6-30.1) with a 5-year disease-free survival rate of 13.5%. Pretreatment tumor size ≥ 2.4 cm [Exp(B) = 3.608, 95%CI: 1.512-8.609, P = 0.044] and radiologic vascular invasion [Exp(B) = 5.553, 95%CI: 2.269-14.589, P = 0.002] were independent predictive factors for neoadjuvant treatment. Borderline resectability [Exp(B) = 0.222, P = 0.008], pancreatic head cancer involving the pancreatic neck [Exp(B) = 9.461, P = 0.001] and arterial invasion [Exp(B) = 6.208, P = 0.010], and adjusted CA19-9 ≥ 50 [Exp(B) = 1.972 P = 0.019] were identified as prognostic clinical factors to predict tumor ***: The suggested preoperative defining system can help with designing treatment plans and also predict oncologic outcomes.

关键词： Preoperative defining system Pancreas head cancer Borderline resectable Adjusted CA19-9 Neoadjuvant therapy

Human umbilical cord blood-derived mesenchymal stem cells promote regeneration of crush-injured rat sciatic nerves

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Neural Regeneration Research 2012年第26期7卷 2018-2027页

作者： Mi-Ae Sung Hun Jong jung jung-woo lee Jin-Yong lee Kang-Mi Pang Sang Bae Yoo Mohammad S. Alrashdan Soung-Min Kim Jeong Won Jahng Jong-Ho lee Department of Craniofacial Structure & Functional Biology School of Dentistry Seoul National University Seoul Republic of Korea Department of Occupation and Environment Postgraduate College of Medicine Konkuk University Choong-ju Republic of Korea Department of Oral & Maxillofacial Surgery School of Dentistry Seoul National University Seoul Republic of Korea Department of Dentistry Oral and Maxillofacial Surgery Ajou University School of Medicine Suwon Republic of Korea Dental Research Institute Seoul National University Seoul Republic of Korea

Several studies have demonstrated that human umbilical cord blood-derived mesenchymal stem cells can promote neural regeneration following brain injury. However, the therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells in guiding peripheral nerve regeneration remain poorly understood. This study was designed to investigate the effects of human umbilical cord blood-derived mesenchymal stem cells on neural regeneration using a rat sciatic nerve crush injury model. Human umbilical cord blood-derived mesenchymal stem cells （1 ~ 106） or a PBS control were injected into the crush-injured segment of the sciatic nerve. Four weeks after cell injection, brain-derived neurotrophic factor and tyrosine kinase receptor B mRNA expression at the lesion site was increased in comparison to control. Furthermore, sciatic function index, Fluoro Gold-labeled neuron counts and axon density were also significantly increased when compared with control. Our results indicate that human umbilical cord blood-derived mesenchvmal stem cells promote the functinnal r~.RcJv^rv nf P.n I^h-inillr^4 ~r^i~tit, n^r~e

关键词： human umbilical cord blood-derived mesenchymal stem cells sciatic nerve crush injury FluoroGold stem cells peripheral nerve regeneration regeneration neural regeneration

TiO2 nanotube branched tree on a carbon nanofiber nanostructure as an anode for high energy and power lithium ion batteries

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Nano Research 2014年第4期7卷 491-501页

作者： Taeseup Song Hyungkyu Han Heechae Choi jung woo lee Hyunjung Park Sangkyu lee Won II Park Seungchul Kim Li Liu Ungyu Paik Department of Materials Science Engineering Hanyang University Seou113 3-791 Korea Center for ComputationalScience Korea Institute of Science and Technology Seou1136-791 Korea School of Chemistry Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education Xiangtan University Xiangtan 411105 China

The inherently low electrical conductivity of TiO2-based electrodes as well as the high electrical resistance between an electrode and a current collector represents a major obstacle to their use as an anode for lithium ion batteries. In this study, we report on high-density TiO2 nanotubes （NTs） branched onto a carbon nanofiber （CNF）＂tree＂ that provide a low resistance current path between the current collector and the TiO2 NTs. Compared to a TiO2 NT array grown directly on the current collector, the branched TiO2 NTs tree, coupled with the CNF electrode, exhibited -10 times higher areal energy density and excellent rate capability （discharge capacity of -150 mA.h.g-1 at a current density of 1,000 mA·g-1）. Based on the detailed experimental results and associated theoretical analysis, we demonstrate that the introduction of CNFs with direct electric contact with the current collector enables a significant increase in areal capacity （mA·h·cm-2） as well as excellent rate capability.

关键词： titanium dioxide carbon nanofibers areal capacity lithium ion batteries

Negative oncologic impact of poor postoperative pain control in left-sided pancreatic cancer

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World Journal of Gastroenterology 2017年第4期23卷 676-686页

作者： Eun-Ki Min Jae Uk Chong Ho Kyoung Hwang Sang Joon Pae Chang Moo Kang woo jung lee Yonsei University College of Medicine Seoul 03722 Department of Hepatobiliary and Pancreatic Surgery Yonsei University College of Medicine Pancreaticobiliary Cancer Clinic Yonsei Cancer CenterSeverance Hospital National Health Insurance Corporation Ilsan Hospital

AIMTo investigate the association between postoperative pain control and oncologic outcomes in resected pancreatic ductal adenocarcinoma (PDAC).METHODSFrom January 2009 to December 2014, 221 patients were diagnosed with PDAC and underwent resection with curative intent. Retrospective review of the patients was performed based on electronic medical records system. One patient without records of numerical rating scale (NRS) pain intensity scores was excluded and eight patients who underwent total pancreatectomy were also excluded. NRS scores during 7 postoperative days following resection of PDAC were reviewed along with clinicopathologic characteristics. Patients were stratified into a good pain control group and a poor pain control group according to the difference in average pain intensity between the early (POD 1, 2, 3) and late (POD 5, 7) postoperative periods. Cox-proportional hazards multivariate analysis was performed to determine association between postoperative pain control and oncologic *** total of 212 patients were dichotomized into good pain control group (n = 162) and poor pain control group (n = 66). Median follow-up period was 17 mo. A negative impact of poor postoperative pain control on overall survival (OS) was observed in the group of patients receiving distal pancreatectomy (DP group; 42.0 mo vs 5.0 mo, P = 0.001). Poor postoperative pain control was also associated with poor disease-free survival (DFS) in the DP group (18.0 mo vs 8.0 mo, P = 0.001). Patients undergoing pancreaticoduodenectomy or pylorus-preserving pancreaticoduodenectomy (PD group) did not show associations between postoperative pain control and oncologic outcomes. Poor patients’ perceived pain control was revealed as an independent risk factor of both DFS (HR = 4.157; 95%CI: 1.938-8.915; P < 0.001) and OS (HR = 4.741; 95%CI: 2.214-10.153; P < 0.001) in resected left-sided pancreatic *** postoperative pain relief durin

关键词： Pancreatic cancer Pancreatectomy Survival Postoperative pain Recurrence