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Effect of Al coating conditions on laser weldability of Al coated steel sheet

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中国有色金属学会会刊：英文版 2009年第4期19卷 946-951页

作者： jung-Han LEE Jong-Do KIM jin-seok OH Seo-Jeong PARK Graduate School Korea Marine University Division of Marine Engineering System Korea Marine University Welding Research Center

Al coated steel sheets with excellent heat resistance,thermal reflection,and corrosion resistance are widely used in various *** laser weldability of the Al coated steel sheet for full penetration welding was *** phenomenon caused by intermixed aluminum and behavior of aluminum in the weld were *** coated steel sheets that have various thickness and coating mass were prepared for laser *** effects of parameters such as welding conditions and Al coating conditions were *** content mixed in the weld after laser welding was evaluated,and then a correlation between the mixed Al and mechanical properties was *** results show that the Al-rich zones which have Fe-Al intermetallic compounds are found in the *** intermetallic compounds cause the decreased strength of the weld.

关键词：铝合金焊接钢板焊接激光焊接 Al涂层金属间化合物涂层钢板涂层质量焊接条件

Impregnation approach for poly(vinylidene fluoride)/tin oxide nanotube composites with high tribological performance

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Journal of Materials Science & Technology 2020年第2期37卷 19-25页

作者： Min Su Park jin Kyu Kim Tong-seok Han jung Tae Park Jong Hak Kim Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul03722Korea Department of Civil and Environmental Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul03722Korea Department of Chemical Engineering Konkuk University120 Neungdong-roGwangjin-guSeoul05029Korea

We report a composite material with the high tribological performance,which consists of onedimensional SnO2 nanotubes(ST)and a high molecular weight poly(vinylidene fluoride)(PVDF)matrix in terms of *** of PVDF in N,N-dimethylformamide(DMF)resulted in a facile penetration of PVDF into the inner hollow voids of ST,leading to the close *** between PVDF and ST results in a beneficial effect on the chain arrangement of PVDF,providing anα-phase with better tribological *** ST incorporation,the friction coefficient decreased by 85.0%to 0.408,and the specific wear rate decreased by 69.1%to 0.412,demonstrating the pivotal role of ST as a self-lubricating material due to a large interactive area and PVDF chain rearrangement.

关键词： SnO2 nanotube Composite Friction coefficient Wear rate

Phosphorylated p70S6K in urothelial carcinoma of the tumor recurrence noninvasive low-grade bladder： correlation with

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Asian Journal of Andrology 2014年第4期16卷 611-617页

作者： Soon-Ja Kim jung Hoon Kim Hui seok jung Tae-jin Lee Kyung Mee Lee In Ho Chang Department of Convergence Medicine and Pharmaceutical Biosciences Chung-Ang University Graduate School Seoul Department of Urology Department of Pathology Chung-Ang University College of Medicine Seoul Korea.

We investigated whether inhibiting phosphorylated p70S6K （p-p70S6K） suppresses the proliferation and growth of noninvasive low-grade urothelial carcinoma （LG-URCa） in vitro and whether p-p70S6K can serve as a predictive biomarker for the recurrence of noninvasive LG-URCa of the bladder in patients. We constructed a tissue microarray （TMA） for 95 LG-URCa and 35 benign urothelium samples and performed immunohistochemical staining for p-p70S6K and p-4E-BP1. A Cox regression model was used to investigate the predictive factors for recurrence of LG-URCa. We investigated the dose-dependent antiproliferative effect of rapamycin, its antiproliferative effect and the growth-inhibition effect of p70S6K siRNA transfection in RT4 and 253J cell lines. The pT1 staged group （P 〈 0.05; hazard ratio （HR）, 2.415） and the high p-p70S6K staining group （P 〈 0.05; HR, 2.249） were independent factors for predicting recurrence. Rapamycin inhibited RT4 and 253J cell proliferation in a dose-dependent manner （r = -0.850, P 〈 0.001 in RT4 cells; r = -0.835, P 〈 0.001 in 253J cells）. RT4 and 253J cell proliferation and growth were inhibited by the transfection of p70S6K siRNA and rapamycin, respectively （P 〈 0.05）. Transfection of p70S6K siRNA resulted in inhibitory effects on cell proliferation and growth that were similar to those of rapamycin. Our results suggest that inhibiting p70S6K phosphorylation is important to prevent recurrence and that p70S6K phosphorylation can be used as a molecular biomarker to predict recurrence of certain LG-URCa of the bladder.

关键词： bladder cancer p7OS6K

Clinicopathological features of familial adenomatous polyposis in Korean patients

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World Journal of Gastroenterology 2016年第17期22卷 4380-4388页

作者： Sung Min jung Yong Sik Yoon seok-Byeong Lim Chang Sik Yu jin Cheon Kim Division of Colon and Rectal Surgery Department of Surgery University of Ulsan College of Medicine Seoul 05505 South Korea Asan Medical Center Seoul 05505 South Korea

AIM: To identify prognostic factors and to correlate APC mutations with clinical features, including extracolic manifestations. METHODS: One hundred thirty-five patients who underwent surgical procedures for familial adenomatous polyposis(FAP) were included. FAP was diagnosed when the number of adenomatous polyps was > 100. Data related to patient, extracoloic manifestations, cancer characteristics, operative procedure, follow up and surveillance were collected. APC mutation testing was performed in the 30 most recent patients. DNA was extracted from peripheral blood and polymerase chain reaction products using 31 primer pairs on APC gene were sequenced. A retrospective study was performed to investigate a causal relationship between prognosis and feature of ***: The mean age of the 51 patients with colorectal cancer(CRC) was older than that of those without CRC(30.5 vs 36.9, P = 0.002). Older individuals were more likely to have colon cancer at the time of FAP diagnosis [odds ratio, 4.75(95%CI: 1.71-13.89) and 5.91(1.76-22.12) for 40-49 years and age > 50 vs age < 30). The number of confirmed deaths was 13 and the median age at death was 40 years(range, 27 to 85 years). Ten of the deaths(76.9%) were from CRC. Another cause of two cases of death were desmoid tumors(15.4%). Development of cancer on remnant rectal or ileal mucosa after surgery was not observed. The APC mutation testing revealed 23 pathogenic mutations and one likely pathogenic mutation, among which were four novel mutations. The correlation between mutational status and clinical manifestations was investigated. Mutations that could prodict poor prognosis were at codon 1309 which located on mutation cluster region, codon 1465 and codon ***: Identification of APC mutations should aid in the diagnosis and counseling of family members in terms of early diagnosis and management of FAP.

关键词： Adenomatous polyposis coli Colorectal neoplasms APC gene Prognosis Survival

Effects of 60 Hz electromagnetic field exposure on testiculargerm cell apoptosis in mice

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Asian Journal of Andrology 2004年第1期6卷 29-34页

作者： jin Sang Lee Sang seok Ahn Kyeong Cheon jung Yoon-Won Kim Sang Kon Lee Institute of Medical Science Hallym University School of Medicine Chunchon 200-060 Korea Department of Urology Hallym University School of Medicine Chunchon 200-060 Korea Department of Pathology Hallym University School of Medicine Chunchon 200-060 Korea Department of Microbiology Hallym University School of Medicine Chunchon 200-060 Korea

Aim: To evaluate the effects of 60 Hz extremely low frequency (ELF) elelctromagnetic field (EMF) exposure on germ cell apoptosis in the testis of mice. Methods: Adult male BALB/c mice (7 weeks of age) were exposed to a 60 Hz EMF of 0.1 mT or 0.5 mT for 24 h/day. A sham-exposed group served as the control. After 8 weeks of exposure, the mice were sacrificed. Germ cell apoptosis in the testis was assessed by histopathological examination, the terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay (TUNEL) and flow cytometric examination of isolated spermatogenic cells stained with 7 aminoactinomycin D (7-AAD). Results: EMF exposure did not significantly affect the body and testis weights, but significantly increased the incidence of germ cell death. The distinguishing morphological feature of EMF exposure was a decrement in the number of well organized seminiferous tubules. Quantitative analysis of TUNEL-positive germ cells showed a significantly higher apoptotic rate in the 0.5 mT exposed mice than that in the sham controls (P<0.05), while the difference between the two exposed groups was insignificant. The TUNEL-positive cells were mainly spermatogonia. In flow cytometry analysis, the percentage of live cells [forward scatter count (FSC)high7-AAD-] was lower in the exposed groups than that in the controls (Figure 5A), but the decrease in viability was not statistically significant. Conclusion: Continuous exposure to ELF EMF may induce testicular germ cell apoptosis in mice.

关键词： electromagnetic field testis apoptosis TUNEL flow cytometry 7-aminoactinomycin D

Reduced interface energy loss in non-fullerene organic solar cells using room temperature-synthesized SnO2 quantum dots

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Journal of Materials Science & Technology 2020年第17期52卷 12-19页

作者： In Su jin Minwoo Park Jae Woong jung Department of Advanced Materials Engineering for Information&Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 446-701Republic of Korea Department of Chemical and Biological Engineering Sookmyung Women's UniversitySeoul 04310Republic of Korea

We herein report the room temperature synthesis of colloidal SnO2 quantum dots and their application in non-fullerene organic solar cells as an excellent electron transport *** thiourea-assisted hydrolysis at room temperature affords the nanocrystalline SnO2 quantum dots with a diameter of 3-4 *** utilization of the SnO2 quantum dots as an electron transporting layer effectively reduces the interfacial trap density and charge recombination in the solar cell devices,leading to not only the reduced energy loss but also excellent photocurrent *** optimized organic solar cells employing SnO2 quantum dots with polyethylenimine ethoxylated achieves power conversion efficiencies up to 12.023%with a VOC,a JSC,and a FF of 0.89 V,18.89 mA cm^–2,and *** work suggest that the SnO2 quantum dot is a promising electron transporting material to construct efficient organic solar cells for practical *** work also demonstrates the key strategy for thiourea-assisted hydrolysis to synthesize fine and nanocrystalline SnO2 quantum dots.

关键词： Energy loss Organic solar cells Interface SnO2 Quantum dots

Simultaneously enhanced efficiency and ambient stability of inorganic perovskite solar cells by employing tetramethylammonium chloride additive in CsPbI2Br

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Journal of Materials Science & Technology 2022年第7期102卷 224-231页

作者： In Su jin Bhaskar Parida Jae Woong jung Department of Advanced Materials Engineering for Information and Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 446-701Republic of Korea Integrated Education Institute for Frontier Materials(BK21 Four) Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 446-701Republic of Korea

Although all-inorganic perovskites possess suitable bandgap and thermal stability for photovoltaic ap-plications,the unstable film morphologies,and poor moisture stabilities lag behind the organic-inorganic hybrid ***,we demonstrate that high qualityα-CsPbI_(2 ) Br films with improved phase sta-bility,high crystallinity,and pinhole-free film morphology was achieved by employing tetramethylammo-nium chloride(TMACl)as an *** a result,the TMACl-added CsPbI_(2) Br films exhibited high power conversion efficiency of 14.12%with an open-circuit voltage of 1.19 V,a short-circuit current density of 15.08 mA/cm^(2),and a fill factor of *** importantly,the TMACl addition imparts hydrophobicity to the film surface of CsPbI_(2) Br,which delivered excellent stability up to 30 days in the ambient condition and thermal stability at 85℃ for 156 h,***,the TMACl-added device also exhibited excellent PCE of 27.16%under indoor light source(1000 lux),which presents a promising approach for designing stable but high performance all-inorganic perovskite solar cells.

关键词： Inorganic perovskite solar cells CsPbI2Br Additive Tetramethylammonium chloride Efficiency

“One stone,two birds”solvent system to fabricate microcrystalline cellulose–Ti_(3)C_(2)T_(x)nanocomposite film as a flexible dielectric and thermally conductive material

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Nano Research 2023年第2期16卷 3240-3253页

作者： Yong-Zhu Yan Shuwei Li Sung Soo Park Wei-jin Zhang Jun seok Lee jung Rae Kim Dong Gi Seong Chang-Sik Ha Department of Polymer Science and Engineering School of Chemical EngineeringPusan National UniversityBusan 46241Republic of Korea School of Chemical and Biomolecular Engineering Pusan National UniversityBusan 46241Republic of Korea Division of Advanced Materials Engineering Dong-Eui UniversityBusan 47340Republic of Korea

A strategy for fabricating microcrystalline cellulose–Ti_(3)C_(2)T_(x)(MCC–MXene)nanocomposite films with high relative permittivity,high thermal conductivity,and excellent mechanical properties was *** MCC–MXene nanocomposite film was fabricated by casting a solution containing N,N-dimethylacetamide/lithium chloride(DMAc/LiCl)-soluble MCC and DMAcdispersible MXene nanosheets,followed by humidity control *** MXene nanosheets greatly enhanced the permittivity of the nanocomposite films owing to interfacial ***,the nanocomposite film with 20 wt.%MXene content achieved a desirable permittivity of 71.4 at 102 Hz(a 770%improvement against that of neat cellulose),while the dielectric loss only increased by 1.8 times(from 0.39 to 0.70).The obtained nanocomposite films with 20 wt.%and 30 wt.%MXene exhibited remarkable in-plane thermal conductivities of 8.523 and 9.668 W∙m^(−1)∙K^(−1),respectively,owing to the uniform dispersion and selfalignment of the MXene layered ***,the uniformly dispersed MXene nanosheets in the MCC network with interfacial interaction(hydrogen bonding)and mechanical entanglement endowed the nanocomposite films with excellent mechanical properties and ***,the thermal stability,water resistance,and antibacterial properties of the nanocomposite films were effectively improved with the introduction of ***,using DMAc/LiCl as the solvent system not only improves the compatibility between MCC and MXene but also avoids the problem of easy oxidation of MXene in aqueous *** the high stability of the MCC–MXene solution and enhanced properties of the MCC–MXene films,the proposed strategy manifests great potential for fabricating natural biomass-based dielectric materials.

关键词： Ti_(3)C_(2)T_(x) microcrystalline cellulose flexible dielectric thermally conductive N,N-dimethylacetamide/lithium chloride(DMAc/LiCl) compatibility

Acute liver injury induces expression of FGF23 in hepatocytes via orphan nuclear receptor ERRγ signaling

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Genes & Diseases 2023年第3期10卷 679-682页

作者： Yoon seok jung Yong-Hoon Kim Kamalakannan Radhakrishnan jung-Ran Noh jung Hyeon Choi Hyo-jin Kim Jae-Ho Jeong Steven Dooley Chul-Ho Lee Hueng-Sik Choi School of Biological Sciences and Technology Chonnam National UniversityGwangju 61186Republic of Korea Laboratory Animal Resource Center Korea Research Institute of Bioscience and Biotechnology125 Gwahak-roYuseong-guDaejeon 34141Republic of Korea Department of Functional Genomics KRIBB School of BioscienceKorea University of Science and Technology(UST)Daejeon 34113Republic of Korea Combinatorial Tumor Immunotherapy MRC Chonnam National University Medical SchoolHwasun-gunJeonnam 58128Republic of Korea Department of Microbiology Chonnam National University Medical SchoolGwangju 61186Republic of Korea Molecular Hepatology Section Medical Faculty MannheimHeidelberg University69117 HeidelbergGermany

Fibroblast growth factor 23(FGF23)is an osteocyte-and osteoblast-derived hormone that primarily regulates phosphate and vitamin D *** FGF23 levels are abnormally increased in pathological conditions like acute or chronic kidney injury,resulting in disease progression as well as increased rates of morbidity and mortality.^(1) However,FGF23 production in acute liver injury is not fully *** this study.

关键词： FGF23 acute vitamin