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International Journal of Ophthalmology(English edition) 2019年第1期12卷 100-105页

作者： Jin-Hwan Park jung-ah huh Jun-Feng Piao Hwa Lee Se-Hyun Baek Department of Ophthalmology Korea University College of Medicine

AIM: To investigate nasolacrimal duct(NLD) volume in Korean patients and to examine the correlation between NLD volume and obstruction. METHODS: Of patients who underwent orbital computed tomography from March 2013 to January 2016, patients diagnosed with NLD obstruction were classified into the patient group and patients without obstruction were classified into the control group. The NLD volume was measured using the Image J program, which showed the NLD in axial,coronal, and sagittal images on computed tomography. RESULTS: The average value of men's NLD volume,265.33±90.57 mm3, was significantly larger than women's,211.87±68.61 mm3(P=0.009). In the patient group, the NLD volume of the obstructed eyes, 242.49±82.93 mm3,and the non-obstructed eyes, 225.20±73.20 mm3, were significantly higher than the control group, 217.61±82.04 mm3(P<0.001, P<0.001). CONCLUSION: The NLD volume is larger in men than in women in Korean adults. If there is NLD obstruction in women, the NLD volume is larger and it is judged that inflammatory reaction caused a chronic change in the bone around the NLD and affect the measurement of NLD volume.

关键词： computed tomography nasolacrimal duct obstruction nasolacrimal duct volume

Long cycle-life aqueous Zn battery enabled by facile carbon nanotube coating on Cu current collector

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Carbon Energy 2024年第6期6卷 151-164页

作者： Beom-Keun Cho Sung-Ho huh So Hee Kim Seungho Yu Jong-Seong Bae jung-Keun Yoo Seung-Ho Yu Department of Chemical and Biological Engineering Korea UniversitySeoulRepublic of Korea Advanced Analysis Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea Energy Storage Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST School Division of Energy and Environment TechnologyKorea University of Science and TechnologySeoulRepublic of Korea Busan Center Korea Basic Science Institute(KBSI)BusanRepublic of Korea Carbon Composites Department Composites Research DivisionKorea Institute of Materials Science(KIMS)ChangwonRepublic of Korea

As an alternative to Li-ion batteries,aqueous Zn batteries have gained attention due to the abundance of Zn metal,low reduction potential(-0.76 V *** hydrogen electrode),and high theoretical capacity(820 mah g^(-1))of multivalent Zn2+***,the growth of Zn dendrites and the formation of irreversible surface reaction byproducts pose challenges for ensuring a long battery lifespan and ***,the Cu foil coated with a single-walled carbon nanotube(SWCNT)layer using a facile doctor blade casting method is *** SWCNT-coated Cu foil demonstrates a significantly longer battery lifespan compared to the bare Cu in the half-cell *** operando optical microscopy imaging,we are able to provide intuitive evidence that Zn deposition occurs between the carbon nanotube(CNT)coating and Cu substrate,in agreement with the computational ***,with various imaging techniques,the flat morphology and homogeneous distribution of Zn beneath the SWCNT layer are *** addition,the full-cell using CNT-coated Cu exhibits a long cycle life compared to the control group,thereby demonstrating improved electrochemical performance with limited Zn for the cycling process.

关键词： aqueous Zn battery carbon nanotube operando imaging surface coating

Health risks of pest control and disinfection workers after the COVID-19 outbreak in South Korea

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Journal of Environmental Sciences 2024年第5期139卷 350-363页

作者： Yun-Hee Choi Da-An huh Lita Kim Sang ji Lee Kyong Whan Moon Department of Health and Safety Convergence Science Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea BK21 FOUR R&E Center for Learning Health System Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea Institute of Sciences Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea Department of Health and Environmental Science Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea

The exposure patterns of pest control and disinfection workers have changed after the coronavirus disease 2019(COVID-19)outbreak,but the health risks of chemical exposure have not been *** identified these workers’chemical exposure patterns and risks before and after the COVID-19 *** used data conducted between 2018(pre-pandemic)and 2021(post-pandemic)from three-year cross-sectional surveys on pest control and disinfection *** and dermal exposure concentrations were estimated using equations based on a biocidal product risk assessment model from the Korean National Institute of Environmental *** non-carcinogenic and carcinogenic risks of chemicals were calculated using the United States Environmental Protection Agency risk assessment *** found that the annual work frequency(50^(th)percentile)of foggers using disinfectants increased the most among all the work types,from 140 uses/year to 176 uses/year after the COVID-19 ***,all chemicals’non-carcinogenic and carcinogenic risks increased regardless of exposure *** the worst scenario(95^(th)percentile),the margin of exposure for citric acid,benzethonium chloride,benzyl-C12-16-alkyldimethyl chlorides,and sodium chlorite of inhalation exposure,and isopropyl alcohol and benzyl-C12-16-alkyldimethyl chlorides of dermal exposure were acceptable(>100)before the COVID-19outbreak but became unacceptable(10^(-6))before and after the COVID-19 outbreak but comparatively high after the COVID-19 ***,significantly more workers experienced health symptoms after the COVID-19outbreak(p<0.05),with the most common being muscle lethargy(31%),skin/face stinging(28.7%),and breath shortness/neck pain(24.1%).

关键词： Biocide Disinfection Health risk assessment Occupational exposure Pest control

Nanomaterial-assisted wearable glucose biosensors for noninvasive real-time monitoring:Pioneering point-of-care and beyond

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Nano Materials Science 2024年第3期6卷 263-283页

作者： Moein Safarkhani Abdullah Aldhaher Golnaz Heidari Ehsan Nazarzadeh Zare Majid Ebrahimi Warkiani Omid Akhavan YunSuk huh Navid Rabiee NanoBio High-Tech Materials Research Center Department of Biological Sciences and BioengineeringInha UniversityIncheon22212Republic of Korea Department of Chemistry Sharif University of TechnologyTehranIran School of Natural Sciences Massey UniversityPrivate Bag 11222Palmerston North4410New Zealand School of Chemistry Damghan UniversityDamghan36716-45667Iran School of Biomedical Engineering University of Technology SydneySydneyNSW2007Australia Department of Physics Sharif University of TechnologyP.O.Box 11155-9161TehranIran Centre for Molecular Medicine and Innovative Therapeutics Murdoch UniversityPerthWA 6150Australia School of Engineering Macquarie UniversitySydneyNew South Wales2109Australia

This review explores glucose monitoring and management strategies,emphasizing the need for reliable and userfriendly wearable sensors that are the next generation of sensors for continuous glucose *** addition,examines key strategies for designing glucose sensors that are multi-functional,reliable,and cost-effective in a variety of *** unique features of effective diabetes management technology are highlighted,with a focus on using nano/biosensor devices that can quickly and accurately detect glucose levels in the blood,improving patient treatment and control of potential diabetes-related *** potential of next-generation wearable and touch-sensitive nano biomedical sensor engineering designs for providing full control in assessing implantable,continuous glucose monitoring is also *** challenges of standardizing drug or insulin delivery doses,low-cost,real-time detection of increased blood sugar levels in diabetics,and early digital health awareness controls for the adverse effects of injectable medication are identified as unmet ***,the market for biosensors is expected to expand significantly due to the rising need for portable diagnostic equipment and an ever-increasing diabetic *** paper concludes by emphasizing the need for further research and development of glucose biosensors to meet the stringent requirements for sensitivity and specificity imposed by clinical diagnostics while being cost-effective,stable,and durable.

关键词： Glucose sensor Biosensor Wearable devices Noninvasive Real-time monitoring

Benefit in physical function and quality of life to nonsurgical treatment of varicose veins: Pilot study

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World Journal of Clinical Cases 2024年第3期12卷 517-524页

作者： Gwon-Min Kim BoKun Kim Minwoo Jang Jong-Hwan Park Miju Bae Chung Won Lee Jong Won Kim Up huh Medical Research Institute Pusan National University School of MedicineYangsan 50612South Korea Future Convergence Research Institute Changwon National UniversityChangwon 51140South Korea Department of Convergence Medical Science School of MedicinePusan National UniversityYangsan 50612South Korea Health Convergence Medicine Laboratory Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Thoracic and Cardiovascular Surgery Pusan National University School of MedicineBiomedical Research InstitutePusan National University HospitalBusan 49241South Korea

BACKGROUND Studies on varicose veins have focused its effects on physical function;however,whether nonsurgical treatments alter muscle oxygenation or physical function remains ***,the differences in such functions between individuals with varicose veins and healthy individuals remain *** To investigate changes in physical function and the quality of life(QOL)following nonsurgical treatment of patients with varicose veins and determine the changes in their muscle oxygenation during *** We enrolled 37 participants(those with varicose veins,n=17;healthy individuals,n=20).We performed the following measurements pre-and post-nonsurgical treatment in the varicose vein patients and healthy individuals:Calf muscle oxygenation during the two-minute step test,open eyes one-leg stance,30 s sit-to-stand test,visual analog scale(VAS)for pain,Pittsburgh sleep quality index,physical activity assessment,and QOL *** Varicose veins patients and healthy individuals differ in most variables(physical function,sleep quality,and QOL).Varicose veins patients showed significant differences between pre-and post-nonsurgical treatment—results in the 30 sit-to-stand test[14.41(2.45)to 16.35(4.11),P=0.018],two-minute step test[162.29(25.98)to 170.65(23.80),P=0.037],VAS for pain[5.35(1.90)to 3.88(1.73),P=0.004],and QOL[39.34(19.98)to 26.69(17.02),P=0.005];however,no significant difference was observed for muscle *** Nonsurgical treatment improved lower extremity function and QOL in varicose veins patients,bringing their condition close to that of healthy *** studies should include patients with severe varicose veins requiring surgery to confirm our findings.

关键词： Varicose vein Nonsurgical treatment Physical function Quality of life Near infrared spectroscopy

Complete peritonectomy and intraperitoneal chemotherapy for recurrent rectal cancer with peritoneal metastasis

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World Journal of Gastroenterology 2009年第6期15卷 756-757页

作者： jung Wook huh Young Jin Kim Hyeong Rok Kim Department of Surgery Chonnam National University Hwasun Hospital and Medical SchoolGwangju 501-757South Korea

A 68-year-old man underwent laparoscopic low anterior resection for rectal carcinoma in December *** 19 mo after the operation,he developed recurrent rectal cancer with peritoneal metastasis. In September 2008,he subsequently underwent a laparotomy with a peritonectomy,omentectomy, splenectomy,and a Hartmann *** intraperitoneal oxaliplatin 750 mg was administered. The patient was discharged with no postoperative complications and has been well with postoperative FOLFOX chemotherapy.

关键词： Peritonectomy Peritoneal metastasis Recurrent rectal cancer

Bilateral superficial cervical plexus block for parathyroidectomy during pregnancy:A case report

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World Journal of Clinical Cases 2022年第13期10卷 4153-4160页

作者： Jun-Young Chung Yo Seob Lee Seung Yeon Pyeon Sang-ah Han Hyub huh Department of Anesthesiology and Pain Medicine Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea Department of Obstetrics&Gynecology Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea Department of Surgery Kyung Hee University Hospital at GangdongCollege of MedicineKyung Hee UniversitySeoul 05278South Korea

BACKGROUND Primary hyperparathyroidism(PHPT)is the most common cause of pregnancyrelated *** can cause maternal and fetal complications in pregnant *** anesthesia for non-obstetric surgery in pregnant women is associated with maternal hazards and concerns regarding long-term neonatal neurocognitive *** removal of the lesion in mid-pregnancy is currently the primary treatment option for pregnant patients with ***,the blood calcium concentration at which surgery should be considered remains under discussion due to the risk of *** SUMMARY A 31-year-old nulliparous woman at 11 wk of gestation was admitted to our hospital for *** patient had a history of intrauterine fetal death with unknown etiology at 16 wk of gestation 1 year *** blood test results showed that the serum calcium level was elevated to 12.9 mg/dL,and the parathyroid hormone level was elevated to 157 pg/*** a neck ultrasound,it revealed a 0.8 cm×1.5 cm sized oval,hypoechoic mass in the upper posterior of the left thyroid gland,which was compatible with parathyroid *** cervical plexus block(SCPB)for parathyroidectomy was *** surgery,the obstetrician checked the status of the fetus,and there were no abnormal *** then her calcium level returned to normal values after one week of surgery and a healthy male neonate of 2910 g was delivered vaginally at 38 wk of *** Our case suggests that SCPB can be an anesthetic option for parathyroidectomy during the first trimester of pregnancy.

关键词： Bilateral superficial cervical plexus block Hypercalcemia Parathyroid adenoma Parathyroidectomy Pregnancy Case report

Large cavernous hemangioma in the cecum treated by laparoscopic ileocecal resection

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World Journal of Gastroenterology 2009年第26期15卷 3319-3321页

作者： jung Wook huh Sang Hyuk Cho Jae Hyuk Lee Hyeong Rok Kim Department of Surgery Chonnam National University Hwasun Hospital and Medical School Department of Pathology Chonnam National University Hwasun Hospital and Medical School

A cavernous hemangioma of the cecum is a rare vascular malformation but is clinically important because of the possibility of massive *** report a case of a large cavernous hemangioma with pericolic inf iltration in t... 详细信息

关键词： Cavernous hemangioma Cecum Laparoscopic surgery

Interactomic study on interaction between lipid droplets and mitochondria

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Protein & Cell 2011年第6期2卷 487-496页

作者： Jing Pu Cheol Woong Ha Shuyan Zhang Jong Pil jung Won-Ki huh Pingsheng Liu National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China Graduate University of Chinese Academy of Sciences Beijing 100101China School of Biological Sciences Research Center for Functional CellulomicsInstitute of MicrobiologySeoul National UniversitySeoul 151-747Republic of Korea

An increasing body of evidence shows that the lipid droplet,a neutral lipid storage organelle,plays a role in lipid metabolism and energy homeostasis through its interaction with ***,the cellular functions and molecular mechanisms of the interaction remain *** we present data from transmission electron microscopy,fluorescence imaging,and reconstitution assays,demonstrating that lipid droplets physically contact mitochondria in vivo and in *** a bimolecular fluorescence complementation assay in Saccharomyces cerevisiae,we generated an interactomic map of protein-protein contacts of lipid droplets with mitochondria and *** lipid droplet proteins Erg6 and Pet10 were found to be involved in 75%of the interactions ***,interactions between 3 pairs of lipid metabolic enzymes were ***,these data demonstrate that lipid droplets make physical contacts with mitochondria and peroxisomes,and reveal specific molecular interactions that suggest active participation of lipid droplets in lipid metabolism in yeast.

关键词： peroxisomes bimolecular fluorescence complementation assay protein-protein interaction lipid metabolism Erg6

EVALUATION OF DUCTILE FRACTURE CRITERIA IN A GENERAL THREE-DIMENSIONAL STRESS STATE CONSIDERING THE STRESS TRIAXIALITY AND THE LODE PARAMETER

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Acta Mechanica Solida Sinica 2013年第6期26卷 642-658页

作者： Yanshan Lou Hoon huh School of Mechanical Aerospace and Systems EngineeringKAIST335GwahangnoDaeduk Science TownDaejeon305-701South Korea

This paper is concerned with evaluation of various ductile fracture criteria in a general three-dimensional stress state of stress triaxiality, the Lode parameter and the equiva- lent plastic strain to fracture. Evaluation is carried out by comparing fracture loci constructed by fracture criteria to experimental results of A12024-T351. Comparison demonstrates that the Modified Mohr-Coulomb criterion and a newly proposed criterion provide sufficient predictabil- ity of fracture strain. Moreover, evaluation is emphasized on the predicted cut-off value for stress triaxiality. The evaluation demonstrates that the Cockcroft-Latham, Brozzo, Oh, Ko-huh and the new criteria coupled a reasonable cut-off value for ductile materials.

关键词： fracture alloys ductile material fracture locus metal forming