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Large retroperitoneal atypical spindle cell lipomatous tumor,an extremely rare neoplasm:A case report

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World Journal of Clinical Cases 2022年第8期10卷 2584-2590页

作者： jung-min Bae Chang-Yeon jung Woo-Sung Yun Joon Hyuk Choi Department of Surgery Yeungnam University College of MedicineDaegu 42415South Korea Kyungpook National University School of Medicine Jung-guDaegu 41944Korea Department of Pathology Yeungnam University College of Medicine Nam-guDaegu 42415Korea

BACKGROUND Atypical spindle cell lipomatous tumor(ASLT)is a rare soft tissue neoplasm with a low potential for *** frequently occurs in the limb and limb ***,large retroperitoneal ASLTs are extremely *** was no concrete case report of retroperitoneal *** SUMMARY An 18-year-old woman presented with abdominal pain and a palpable *** computed tomography revealed a large fatty mass that was approximately 30 cm in size and filled the entire abdominal *** excision was *** tumor did not invade the adjacent *** pelvic cavity was then too narrow to dissect *** mass was successfully excised without tumor rupture or adjacent organ ***,the neoplasm was a well-differentiated adipocytic *** staining showed that the spindle cells were positive for CD34 and desmin,in addition to multifocal positivity for S100 *** histological features were consistent with an *** patient’s postoperative course was *** the 12-mo followup,no evidence of recurrence or metastasis was *** To the best of our knowledge,our study is the first concrete report of a large retroperitoneal ASLT in the English *** the large retroperitoneal ASLT located in the pelvic cavity,which made it too narrow and tight to dissect,complete excision is difficult but very important because of recurrence *** large retroperitoneal ASLTs are considered extremely rare,their detection is important for accurate evaluation and *** to their significant rarity,retrospective multicenter case studies are required to determine the clinicopathologic characteristics.

关键词： Neoplasms Retroperitoneal space Spindle cell Case report

Gastric cancer occurring in a patient with Plummer-Vinson syndrome: A case report

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World Journal of Gastroenterology 2005年第44期11卷 7048-7050页

作者： Ki-Han Kim min-Chan Kim Ghap-Joong jung Department of Surgery

Plummer-Vinson syndrome (sideropenic dysphagia) is characterized by dysphagia due to an upper esophageal or hypopharyngeal web in patients with chronic iron deficiency anemia. The main cause of dysphagia is the presence of the web in the cervical esophagus,and abnormal motility of the pharynx or esophagus is also found to play a significant role in this *** syndrome is thought to be precancerous because squamous cell carcinoma of hypopharynx, oral cavity or esophagus takes place in 10% of those patients suffering from this malady, but it is even more unusual that Plummer-Vinson syndrome should be accompanied by gastric cancer. We have reported here a case of a43-year-old woman with Plummer-Vinson syndrome who developed stomach cancer and recovered after a radical total gastrectomy with D2 nodal dissection.

关键词： Plummer-Vinson syndrome Gastric cancer Esophageal web

Learning curve of laparoscopy-assisted distal gastrectomy with systemic lymphadenectomy for early gastric cancer

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World Journal of Gastroenterology 2005年第47期11卷 7508-7511页

作者： min-Chan Kim Ghap-Joong jung Hyung-Ho Kim Ghap-Joong jung Department of SurgeryDong-A University College of MedicineBusanKorea Department of Surgery Seoul National University Bundang HospitalGyeonggi-doKorea

AIM: To evaluate the nature of the 'learning curve' for laparoscopy-assisted distal gastrectomy (LADG) with systemic lymphadenectomy for early gastric cancer. METHODS: The data of 90 consecutive patients with early gastric cancer who underwent LADG with systemic lymphadenectomy between April 2003 and November 2004 were reviewed. The 90 patients were divided into 9 sequential groups of 10 cases in each group and the average operative time of these 9 groups were determined. Other learning indicators, such as transfusion requirements, conversion rates to open surgery, postoperative complication, time to first flatus, and postoperative hospital stay, were evaluated. RESULTS: After the first 10 LADGs, the operative time reached its first plateau (230-240 min/operation) and then reached a second plateau (＜200 min/operation) for the final 30 cases. Although a significant improvement in the operative time was noted after the first 50 cases, there were no significant differences in transfusion requirements, conversion rates to open surgery, postoperative complications, time to first flatus, or postoperative hospital stay between the groups. CONCLUSION: Based on operative time analysis, this study show that experience of 50 cases of LADG with systemic lymphadenectomy for early gastric cancer is required to achieve optimum proficiency.

关键词： Laparoscopic gastrectomy, Systemic lymphadenectomy Learning curve

Regeneration-associated macrophages： a novel approach to boost intrinsic regenerative capacity for axon regeneration

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Neural Regeneration Research 2016年第9期11卷 1368-1371页

作者： min jung Kwon Hyuk Jun Yoon Byung Gon Kim Department of Brain Science Ajou University School of Medicine Suwon Republic of Korea Department of Neurology Ajou University School of Medicine Suwon Republic of Korea Neuroscience Graduate Program Department of Biomedical Sciences Ajou University Graduate School of Medicine Suwon Republic of Korea

Axons in central nervous system （CNS） do not regenerate spontaneously after injuries such as stroke and traumatic spinal cord iniury. Both intrinsic and extrinsic factors are responsible for the regeneration fail- ure, Although intensive research efforts have been invested on extrinsic regeneration inhibitors, the extent to which glial inhibitors contribute to the regeneration failure in viva still remains elusive. Recent exper- imental evidence has rekindled interests in intrinsic factors for the regulation of regeneration capacity in adult mammals. In this review, we propose that activating macrophages with pro-regenerative molecular signatures could be a novel approach for boosting intrinsic regenerative capacity of CNS neurons. Using a conditioning injury model in which regeneration of central branches of dorsal root ganglia sensory neu- rons is enhanced by a preceding injury to the peripheral branches, we have demonstrated that perineuronal macrophages surrounding dorsal root ganglia neurons are critically involved in the maintenance of en- hanced regeneration capacity. Neuron-derived chemokine （C-C motif） ligand 2 （CCL2） seems to mediate neuron-macrophage interactions conveying injury signals to perineuronal macrophages taking on a soley pro-regenerative phenotype, which we designate as regeneration-associated macrophages （RAMs）. Ma- nipulation of the CCL2 signaling could boost regeneration potential mimicking the conditioning injury, suggesting that the chemokine-mediated RAM activation could be utilized as a regenerative therapeutic strategy for CNS injuries.

关键词： axon regeneration conditioning injury neuron-macrophage interaction regeneration-associatedmacrophage cAMP CCL2 M2 polarization spinal cord injury

Prediction of grain structure in direct-chill cast Al–Zn–Mg–Cu billets using cellular automaton-finite element method

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Progress in Natural Science:Materials International 2021年第3期31卷 434-441页

作者： min-Seok Kim Sang-Hwa Lee Jae-Gil jung Kwangjun Eah Department of Materials Science and Engineering Gachon University Metallic Materials Division Korea Institute of Materials Science Department of Materials Science and Engineering Yonsei University

A cellular automaton-finite element(CA-FE) model was used to predict the solidification grain structure of permanent mold cast A7086 alloy. In this model, a Gaussian distribution of nucleation sites was adopted, and the Kurz-Giovanola-Trivedi model was extended to a multicomponent Al–Zn–Mg–Cu alloy system to determine the growth kinetics of the dendrite tip. For describing the Gaussian distribution of nucleation sites on the mold surface, an empirical relationship between the initial cooling rate of the melt and the nucleation density was proposed. Under various casting conditions, the calculated grain structures agreed well with the experimental results. Subsequently, the model was applied to the direct-chill(DC) cast billets, and the simulated grain structures reproduced well the experimental results. This confirmed that the current CA-FE model can be used practically and effectively in DC casting processes.

关键词： Cellular automaton-finite element (CA-FE) model Direct-chill casting Al–Zn–Mg–Cu alloy A7068 alloy Grain structure

Dual function of a high-contrast hydrophobic-hydrophilic coating for enhanced stability of perovskite solar cells in extremely humid environments

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Nano Research 2017年第11期10卷 3885-3895页

作者： Jin Sun Yoo Gill Sang Han Seongha Lee min Cheol Kim Mansoo Choi Hyun Suk jung jung-Kun Lee School of Advanced Materials Science amp Engineering Sungkyunkwan University Suwon 440-746 Republic of Korea Department of Mechanical Engineering and Materials Science University of Pittsburgh Pittsburgh Pennsylvania 15261 USA Department of Mechanical and Aerospace Engineering Seoul National University Seoul 08826 Republic of Korea

In spite of a continuous increase in their power conversion efficiency （PCE） and an economically viable fabrication process,organic-inorganic perovskite solar cells （PSCs） pose a significant problem when used in practical applications：They show fast degradation of the PCE when exposed to very humid *** this study,the stability of PSCs under very humid conditions is greatly enhanced by coating the surface of the PSC devices with a multi-layer film consisting of ultrahydrophobic and relatively hydrophilic layers.A hydrophobic composite of poly（methyl methacrylate）（PMMA）,polyurethane （PU）,and SiO2 nanoparticles successfully retards the water molecules from very humid ***,the hydrophilic layer with moderately PMMA captures the residual moisture within the perovskite layer;subsequently,the perovskite layer *** dual function of the coating film keeps the PCE of PSCs at 17.3% for 180 min when exposed to over 95% humidity.

关键词： perovskite solar cell stability surface coating ultrahydrophobic self-recovery

Stomach cancer screening and preventive behaviors in relatives of gastric cancer patients

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World Journal of Gastroenterology 2011年第30期17卷 3518-3525页

作者： jung min Kang Dong Wook Shin Young min Kwon Sang min Park min Sun Park Jin Ho Park Ki Young Son Be Long Cho Department of Family Medicine Seoul National University Hospital101 DaehangnoJongno-Gu110-744 SeoulSouth Korea

AIM:To investigate gastric cancer screening and preventive behaviors among the relatives of patients with gastric cancer[i.e.,gastric cancer relatives(GCRs)].METHODS:We examined the Korean National Health and Nutrition Examination Survey 2005(KNHANESⅢ) database and compared the gastric cancer screening and preventive behaviors of GCRs(n=261)with those of non-GCRs(n=454)and controls without a family history of cancer(n=2842).RESULTS:The GCRs were more likely to undergo gastric cancer screening compared with the control group(39.2%vs 32.3%,adjusted odds ratio:1.43,CI:1.05-1.95),although the absolute screening rate was *** patterns and smoking rates did not differ significantly between the groups,and a high proportion of GCRs reported inappropriate dietary habits(i.e.,approximately 95%consumed excessive sodium,30% were deficient in vitamin C,and 85%were deficient in dietary fiber).CONCLUSION:The gastric cancer screening and preventive behaviors of GCRs have yet to be *** increase awareness among GCRs,systematic family education programs should be implemented.

关键词： Family history of cancer Cancer relatives Gastric cancer screening Preventive behaviors Cancerprevention

A new technique for Nd:YAG laser posterior capsulotomy

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 345-349页

作者： jung Kee min Jae Hwan An Jin Ho Yim Department of Ophthalmology Ulsan University HospitalUlsan University College of Medicine 290-3 Jeonha-dongDong-gu Ulsan 682-714 Republic of Korea Samsung Eye Clinic Cheongju 361-270 Republic of Korea

AIM:To investigate the effects of a new opening pattern in neodymium:yttrium-aluminum-garnet(Nd:YAG)laser posterior capsulotomy on visual ***:This technique was conducted along a circular *** energy ranged between 0.8 and1.2 mJ/pulse was consumed and mean total energy levels were 74±21 mJ(mean±standard deviation:SD,from 40 to167)and laser shots aimed at 150μm away behind a datum point and went along an imaginary line which extends 0.5 mm inside from optic margin and into the circular en bloc *** stands were attached with fragment and then they were cut off by the laser after circular *** circular fragment was completely separated from vitreous,and then this fragment was quickly sunk in intravitreal ***:The follow-up period ranges from at least a week to 40mo,making 15.8mo on *** procedural outcome showed 96%(74 eyes out of the 77eyes)enhancement in patients’visual *** macular edema or retinal detachment was not observed in any of the patients during follow-up ***:This new technique is expected to improve the weaknesses that the conventional procedures have by adding the process to cut off vitreous stands attached with the fragment by the laser to the circular application.

关键词： cataract intraocular lens damage posterior capsular opacification vitreous strand YAG laser capsulotomy

The Arabidopsis AP2/ERF Transcription Factor RAP2.11 Modulates Plant Response to Low-Potassium Conditions

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Molecular Plant 2012年第5期5卷 1042-1057页

作者： min jung Kim Daniel Ruzicka Ryoung Shin Daniel P. Schachtman Donald Danforth Plant Science Center St Louis MO 63132 USA RIKEN Plant Science Center Yokohama Kanagawa 230-0045 Japan Present address:Monsanto Company 700 Chesterfield Parkway Chesterfield MO 63017 USA

Plants respond to low-nutrient conditions through metabolic and morphology changes that increase their ability to survive and grow. The transcription factor RAP2.11 was identified as a component in the response to low potassium through regulation of the high-affinity K＋ uptake transporter AtHAK5 and other components of the low- potassium signal transduction pathway. RAP2.11 was identified through the activation tagging of Arabidopsis lines that contained a luciferase marker driven by the AtHAK5 promoter that is normally only induced by low potassium. This factor bound to a GCC-box of the AtHAK5 promoter in vitro and in vivo. Transcript profiling revealed that a large number of genes were up-regulated in roots by RAP2.11 overexpression. Many regulated genes were identified to be in functional cate- gories that are important in Iow-K＋ signaling. These categories included ethylene signaling, reactive oxygen species pro- duction, and calcium signaling. Promoter regions of the up-regulated genes were enriched in the GCCGGC motif also contained in the AtHAK5 promoter. These results suggest that RAP2.11 regulates AtHAK5 expression under Iow-K＋ con- ditions and also contributes to a coordinated response to low-potassium conditions through the regulation of other genes in the Iow-K＋ signaling cascade.

关键词： potassium deprivation transport transcription factor nutrient sensing signal transduction.