检索结果-南通市图书馆

Role of adjuvant chemoradiotherapy and chemotherapy in patients with resected gallbladder carcinoma: a multiinstitutional analysis (KROG 19-04)

引用

Cancer Biology & Medicine 2022年第6期19卷 931-944页

作者： Sung Uk Lee Jinsil Seong Tae Hyun Kim jung ho im Woo Chul Kim Kyubo Kim Hae Jin Park Tae Gyu Kim Youngkyong Kim Bae Kwon Jeong Jin Hee Kim Byoung Hyuck Kim Taek-Keun Nam Center for Proton Therapy and Center for Liver and Pancreatobiliary Cancer National Cancer CenterGoyang 10408Korea Department of Radiation Oncology Yonsei Cancer CenterYonsei University College of MedicineSeoul 03722Korea Department of Radiation Oncology CHA Bundang Medical CenterCHA University School of MedicineSeongnam 13497Korea Department of Radiation Oncology Inha University HospitalInha University School of MedicineIncheon 22332Korea Department of Radiation Oncology Ewha Womans University Mokdong HospitalEwha Womans University College of MedicineSeoul 07985Korea Department of Radiation Oncology Hanyang University Medical CenterHanyang University College of MedicineSeoul 04763Korea Department of Radiation Oncology Samsung Changwon HospitalSungkyunkwan University School of MedicineChangwon 51353Korea Department of Radiation Oncology Kyung Hee University HospitalKyung Hee University College of MedicineSeoul 02447Korea Department of Radiation Oncology Gyeongsang National University HospitalGyeongsang National University College of MedicineJinju 52727Korea Department of Radiation Oncology Dongsan Medical CenterKeimyung University School of MedicineDaegu 41931Korea Department of Radiation Oncology Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 07061Korea Department of Radiation Oncology Chonnam National University Hwasun HospitalChonnam National University College of MedicineHwasun 58128Korea

Objective:The effectiveness of adjuvant treatments for resected gallbladder carcinoma(GBC)has remained unclear due to lack of randomized controlled trials;thus,the aim of present study was to evaluate the role of adjuvant treatments,including chemoradiotherapy(CRT)and/or chemotherapy(CTx),in patients with resected ***:A total of 733 GBC patients who received curative-intent surgical resection were identified in a multi-institutional *** 733 patients,372(50.8%)did not receive adjuvant treatment,whereas 215(29.3%)and 146(19.9%)received adjuvant CTx and CRT,*** locoregional recurrence-free survival(LRFS),recurrence-free survival(RFS),and overall survival(OS)of the adjuvant treatment groups were compared according to tumor stage(stage II *** III–IV).Results:In stage II disease(n=381),the 5-year LRFS,RFS,and OS were not significantly different among the no-adjuvant therapy,CTx,and CRT groups,and positive resection margin,presence of perineural invasion,and Nx classification were consistently associated with worse LRFS,RFS,and OS in the multivariate analysis(P<0.05).For stage III–IV(n=352),the CRT group had significantly higher 5-year LRFS,RFS,and OS than the no-adjuvant therapy and CTx groups(67.8%,45.2%,and 56.9%;37.9%,28.8%,and 35.4%;and 45.0%,30.0%,and 45.7%,respectively)(P<0.05).Conclusions:CRT has value as adjuvant treatment for resected GBC with stage III–IV *** study is needed for stage II disease with high-risk features.

关键词： Gallbladder cancer adjuvant treatment chemoradiotherapy locoregional recurrence-free survival overall survival

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CORE:Common Region Extension Based Multiple Protein Structure Alignment for Producing Multiple Solution

引用

Journal of Computer Science & Technology 2013年第4期28卷 647-656页

作者： Woo-Cheol Kim Sanghyun Park jung-im Won College of Information Sciences and Technology The Pennsylvania State University University Park Department of Computer Science Yonsei University Research Center of Information and Electronic Engineering Hallym University Chuncheon

Over the past several decades, biologists have conducted numerous studies examining both general and specific functions of proteins. Generally, if similarities in either the structure or sequence of amino acids exist for two proteins, then a common biological function is expected. Protein function is determined primarily based on the structure rather than the sequence of amino acids. The algorithm for protein structure alignment is an essential tool for the research. The quality of the algorithm depends on the quality of the similarity measure that is used, and the similarity measure is an objective function used to determine the best alignment because of their individual strength and weakness however, none of existing similarity measures became golden standard They require excessive filtering to find a single alignment. In this paper, we introduce a new strategy that finds not a single alignment, but multiple alignments with different lengths. This method has obvious benefits of high quality alignment. however, this novel method leads to a new problem that the running time for this method is considerably longer than that for methods that find only a single alignment. To address this problem~ we propose algorithms that can locate a common region （CORE） of multiple alignment candidates, and can then extend the CORE into multiple alignments. Because the CORE can be defined from a final alignment, we introduce CORE＊ that is similar to CORE and propose an algorithm to identify the CORE＊. By adopting CORE＊ and dynamic programming, our proposed method produces multiple alignments of various lengths with higher accuracy than previous methods. In the experiments, the alignments identified by our algorithm are longer than those obtained by TM-align by 17% and 15.48%, on average, when the comparison is conducted at the level of super-family and fold, respectively.

关键词： structure alignment similarity search protein structure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Concept study of measuring gravitational constant using superconducting gravity gradiometer

引用

Chinese Physics B 2018年第8期27卷 130-135页

作者： Xing Bian ho jung Paik Martin Vol Moody University of Chinese Academy of Sciences Beijing 100049China Technical Institute of Physics and Chemistry Chinese Academy of SciencesBeijing 100190China Department of Physics University of MarylandCollege ParkMaryland 20742USA

Newton＇s gravitational constant G is the least known fundamental constant of nature. Since Cavendish made the first measurement of G with a torsion balance over two hundred years ago, the best results of G have been obtained by using torsion balances. however, the uncorrected anelasticity of torsion fibers makes the results questionable. We present a new method of G measurement by using a superconducting gravity gradiometer constructed with levitated test masses, which is free from the irregularities of mechanical suspension. The superconducting gravity gradiometer is rotated to generate a centrifugal acceleration that nulls the gravity field of the source mass, forming an artificial planetary system. This experiment has a potential accuracy of G better than 10 ppm.

关键词： gravitational constant superconducting gravity gradiometer artificial planetary system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Formation Mechanism of Chunky Graphite and Its Preventive Measures

引用

Journal of Materials Science & Technology 2008年第3期24卷 289-295页

作者： Hideo Nakae Sanghoon jung ho-Chul Shin Department of Materials Science and Engineering Waseda University National Institute of AIST Corporate Res.and Dev.Div. Hyundai.Kia Motors

The formation mechanism of chunky graphite has been reviewed and studied. The study consisted of a unidirectional solidification method, a small droplet method and a furnace cooling method. Four kinds of iron samples were prepared, namely, the pure Fe-C, Fe-C-S, Fe-C-Ce and Fe-C-Si-Ce alloys, and three kinds of nickel samples, namely the Ni-C, Ni-C-S and Ni-C-Mg alloys. The results of the unidirectional solidification of the Ni-C alloys showed that spheroidal graphite is not observed in the continuous solidified region, in which only flake-like graphite is observed, while spheroidal graphite is usually observed in the quenched liquid region. The existence of spheroidal graphite in the solidified phase is recognized only in the discontinuous growth mode of the Ni-C-Mg alloy solidified at 150 mm/h. This means that the spheroidal graphite is directly crystallized from the melt and entrapped by the flake-like chunky graphite that is formed by the continuous growth mode. In the small droplet method, a small piece of the Fe-C or Fe-C-Ce sample was melted on a pure graphite plate then cooled at a different cooling rate in a He-3%H2 atmosphere. The graphite in the Fe-C-Ce alloy is usually spherical. Nevertheless, the graphite morphology of the final solidified area changed from spherical to chunky and chunky to ledeburite with an increase in the cooling rate. This means that the chunky graphite is formed in the residual liquid region by the solidification into Fe-graphite system. The sample was cooled in a furnace, and the graphite morphology changes from spherical to chunky and chunky to ledeburite with the decrease in the Si content. These phenomena can be confirmed by the cooling curves of these samples.

关键词： Chunky graphite Spheroidal graphite Solidification Cooling curve

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Interfacial modulation of bifunctional electrolyte additive engineering for dendrite-free and robust lithium metal anode

引用

Journal of Energy Chemistry 2024年第10期97卷 120-127,I0003页

作者： Mahammad Rafi Shaik Yongmin Park Young-Kwang jung Won Bin im Division of Materials Science and Engineering Hanyang University222Wangsimni-roSeongdongguSeoul 0473Republic of Kor Department of Chemical Engineering and Biotechnology University of CambridgeCambridge CB3 OASUK

Anode materials for rechargeable electric car batteries are obtained from Li-metal owing to their extremely high specific capacity and low redox ***,safety concerns related to dendrite formation on the anode surface caused by the uneven distribution of Li-ions during the discharge process interfere with the use of Li-metal in industrial *** this study,methyl vinyl sulfone(MVS),a sulfone-based functional electrolyte additive,is used in an additive engineering strategy to control Lielectrolyte interactions and address the aforementioned *** dendrite growth may be restricted,and transition metal degradation on the surface of the cathode can be reduced by the MVS-derived functional electrolyte additive interfacial *** electrochemical performance of an ethylene carbonate/dimethyl carbonate(EC/DMC)+1 wt% MVS Li-metal anode of a Li||Li symmetric cell exhibits remarkable cycle stability,maintaining a low overvoltage for over 750 h at 1 mA cm^(-2),and capacity of 1 mA h cm^(-2).Additionally,LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811) full cells with the MVS additive exhibit enhanced electrochemical stability for 250 cycles at a current density of 100 mA g^(-1).This study provides an innovative approach for stabilizing the metal-electrolyte interfacial layer that may be used for practical applications in metal-based rechargeable batteries.

关键词： Lithium rechargeable battery Dendrite-free Electrolyte additive Bifunctional electrolyte Interfacial layer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In-situ formation of MOF derived mesoporous Co3N/amorphous N-doped carbon nanocubes as an efficient electrocatalytic oxygen evolution reaction

引用

Nano Research 2019年第7期12卷 1605-1611页

作者： Bong Kyun Kang Seo Young im Jooyoung Lee Sung hoon Kwag Seok Bin Kwon SintayehuNibret Tiruneh Min-Jun Kim jung ho Kim Woo Seok Yang Byungkwon Lim Dae ho Yoon Nano Materials and Components Research Center Korea Electronics Technology InstituteSeongnam 463-816Republic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan University Suwon 440-746Republic of Korea Advanced Materials & Processing Center Institute for Advanced Engineering (IAE)Yongin 175-28Republic of Korea Australian Institute for Innovative Materials (AIim) University of WollongongSquires WayNorth Wollongong NSW 2500Australia Department of Advanced Materials Engineering for Information and Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do17104Republic of Korea

The suitable materials,metal nitrides,are a promising class of electrocatalyst materials for a highly efficient oxygen evolution reaction (OER) because they exhibit superior intrinsic conductivity and have higher sustainability than oxide-based *** our knowledge,for the first time,we report a designable synthesis of three-dimensional (3D) and mesoporous Co3N@ amorphous N-doped carbon (AN-C) nanocubes (NCs) with well-controlled open-framework structures via monodispersed Co3[Co(CN)6]2 Prussian blue analogue (PBA) NC precursors using in situ nitridation and calcination ***3N@AN-C NCs (2 h) demonstrate better OER activity with a remarkably low Tafel plot (69.6 mV-dec-1),low overpotential of 280 mV at a current density of 10 ***,excellent cycling stability in alkaline electrolytes was exhibited without morphological changes and voltage elevations,superior to most reported hierarchical structures of transition-metal nitride *** presented strategy for synergy effects of metal-organic frameworks (MOFs)-derived transition-metal nitrides-carbon hybrid nanostructures provides prospects for developing high-performance and advanced electrocatalyst materials.

关键词： transition-metal nitride metal organic framework mesoporous oxygen evaluation reaction alkaline water electrolysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Application of Thermodynamic Database to Corrosion of ZrO_(2) Containing Submerged Entry Nozzle in Steel Continuous Casting Process

引用

China's Refractories 2024年第2期33卷 10-15页

作者： In-ho jung Department of Materials Science and Engineering Seoul National UniversitySeoul 08826South Korea Research Institute of Advanced Materials Seoul National UniversitySeoul 08826South Korea

The CALPHAD thermodynamic databases are very useful to analyze the complex chemical reactions happening in high temperature material *** FactSage thermodynamic database can be used to calculate complex phase diagrams and equilibrium phases involving refractories in industrial *** this study,the FactSage thermodynamic database relevant to ZrO_(2)-based refractories was reviewed and the application of the database to understanding the corrosion of continuous casting nozzle refractories in steelmaking was presented.

关键词： thermodynamic database ZrO_(2)containing submerged entry nozzle continous casting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fossil-Winged Fruits of Fraxinus(Oleaceae) and Liriodendron(Magnoliaceae) from the Duho Formation,Pohang Basin,Korea

引用

Acta Geologica Sinica(English Edition) 2009年第5期83卷 845-852页

作者： Seung-ho jung Seong-Joo LEE Department of Geology Kyungpook National UniversityDaegu 702-701Korea

A total of 16 specimens of fossil-winged fruits were found from the Middle Miocene marine deposits, Duho Formation, Pohang Basin, Korea. They were identified into two structurally different groups： 15 specimens into a winged fruit of Fraxinus, and one specimen of Liriodendron. The most samaras （13 specimens） were identified as Fraxinus oishii, which is characterized by narrowly ovate or ovate-elliptic shapes that are 2.7-3.6 cm in length and 0.7-1 cm in width （i/w ratio=3.4-4）. The apexes of the Fraxinus oishii samara are round or slightly emarginated, and a seed of the samara is always located at the base, of which the general shape is narrow rhombic-ellipsoidal. The seed is 1.2-2 cm long and 0.5-0.7 cm wide. Two specimens are different from the samara of Fraxinus oishii. They have a 6.6 length/width ratio （3.3 cm long and 0.5 cm wide）, and thus, are temporarily classified into the Fraxinus sp. One specimen was recognized as a winged seed of Liriodendron meisenense. The wing is broadly lanceolate to elliptic in shape, has a smooth, acute apex, and is approximately 3 cm long and 0.7 cm wide. Samaras of Fraxinus oishii and Liriodendron meisenense were early reported from the Middle Miocene deposits from North Korea, but these specimens are the first discovery in South Korea. Further study of the Duho Formation may connect flora relationships between North and South Korea.

关键词： winged fruits Fraxinus Liriodendron Middle Miocene Pohang Basin Korea

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Possibility of Solid Hydrometeor Growth Zone Identification Using Radar Spectrum Width

引用

Advances in Atmospheric Sciences 2023年第2期40卷 317-332页

作者： Sung-ho SUH Eun-ho ChoI hong-Il Kim Woonseon jung Flight Safety Technology Division NARO Space CenterKorea Aerospace Research Institute(KARI)508 Haban-roBongrae-myeonGoheung-gunJeollanam-do 59571Republic of Korea Research Applications Department National Institute of Meteorological Sciences33Seohobuk-roSeoqwipo-siJeju-do 63568Republic of Korea

In this study,the correlation between simulated and measured radar velocity spectrum width(σ_(v))is *** results show that the dendrites growth zones(DGZs)and needles growth zones(NGZs)mostly contain dendrites(DN)and needles(NE),***σ_(v) zones(1.11.2 m s^(-1),a differential reflectivity(ZDR)higher than 0 dB,and a cross-correlation coefficient(ρhv)less than *** contrast,prolate particles with relatively uniform shapes were observed in the NGZ withσ_(v)imulation results show that the DN exhibited a largerσ_(v) compared to the NE,and this observedσ_(v) was strongly dependent on the wind fluctuations(v’)due to turbulence or wind *** contrast,the NE exhibited a significantly smallσ_(v)~0.55 m s^(-1),which converges irrespective of v’.In addition,a strong correlation between the measuredσ_(v) values at five radar elevation angles(θ=6.2°,9.1°,13.1°,19°,and 80°)and those simulated in this study confirmed the significance of the analysis results.

关键词： spectrum width weather radar aerodynamic properties dendritic growth zone hydrometeor classifications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Central Composite Design for Optimized Extraction of Polysaccharides from Undaria pinnatifida

引用

Chemical Research in Chinese Universities 2012年第4期28卷 620-623页

作者： HEO Hyo-jung ROW Kyung-ho Department of Chemical Engineering Inha University253 Yonghyun-DongNam-KuIncheon 402-751Korea

Response surface methodology was used to optimize the extraction conditions of polysaccharides from Undaria *** effects of three independent variables,extraction time,extraction temperature and ratio of water to raw material were investigated by a central composite *** experimental data were fitted to a second-order polynomial equation via multiple regression analysis and also examined with the appropriate statistical *** adjusted coefficient of determination（R^2Adj） for the model was *** optimum extraction yield of 30.78% was obtained when the extraction temperature was 95 °C,extraction time was 4.5 h,and the ratio of water to raw material was 35（mL/g）.Under these conditions,validation experiments were done and the mean extraction yield of polysaccharides was 30.79%,which was in good agreement with the predicted model value.

关键词： Undaria pinnatifida Optimization Extraction Polysaccharide Response surface methodology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：