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The 6-hour lactate clearance rate in predicting 30-day mortality in cardiogenic shock

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Journal of Intensive Medicine 2024年第3期4卷 393-399页

作者： junfeng Wang Mingxia Ji Department of Intensive Care Unit Yiwu Central HospitalYiwuZhejiangChina

Background Early evaluation of prognosis in cardiogenic shock(CS)is crucial for tailored treatment *** lactate clearance and lactate levels are considered useful prognostic biomarkers in patients with ***,there is yet no literature comparing the 6-hour lactate clearance rate(Δ6Lac)with lactate levels measured at admission(L1)and after 6 h(L2)to predict 30-day mortality in *** In this observational cohort study,95 patients with CS were treated at Department of Intensive Care Unit,Yiwu Central Hospital between January 2020 and December *** these,88 patients met the eligibility *** lactate levels were measured after admission(L1)as the baseline lactate value,and were measured after 6 h(L2)following *** primary endpoint of the study was survival rate at 30 days.A receiver operating characteristic curve was used for data *** and multivariate Cox regression analyses were performed based onΔ***–Meier(KM)survival curves were generated to compare the 30-day survival rates among L1,L2,andΔ*** TheΔ6Lac model showed the highest area under the curve value(0.839),followed by the L2(0.805)and L1(0.668)***Δ6Lac model showed a sensitivity of 84.2%and specificity of 75.4%.The L1 and L2 models had sensitivities of 57.9%each and specificities of 89.9%and 98.6%,*** cut-off values forΔ6Lac,L1,and L2 were 18.2%,6.7 mmol/L,and 6.1 mmol/L,*** Cox regression analysis revealed a significant association betweenΔ6Lac and 30-day *** adjusting for five models in multivariate Cox regression,Δ6Lac remained a significant risk factor for 30-day mortality in patients with *** our fifth multivariate Cox regression model,Δ6Lac remained a risk factor associated with 30-day mortality(hazard ratio[HR]=5.14,95%confidence interval[CI]:1.48 to 17.89,P=0.010)as well as L2(HR=8.42,95%CI:1.26 to 56.22,P=0.028).The KM survival curve analysis revealed that L1>6.7 mmol/L(HR=8.08,95%

关键词： Lactates The 6-h lactate clearance rate Cardiogenic shock Mortality Cox regression

Effects of Fatigue Characteristics on Static and Dynamic Performance of Eucommia Rubber Isolators

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Journal of Applied Mathematics and Physics 2023年第7期11卷 2165-2177页

作者： Yongsheng Peng junfeng yang Guopei Pan Jianan Zhang Zhuo Wang Shanghai Marine Equipment Research Institute Shanghai China

This study aimed to investigate the effect of fatigue characteristics on the static and dynamic performance of Eucommia ulmoides gum isolators, and to explore the performance changes of Eucommia ulmoides gum isolators with different formulations. For this purpose, we used five formulations of Eucommia ulmoides gum isolators and set different fatigue test methods to study the static and dynamic performance changes of Eucommia ulmoides gum isolators with different formulations by changing the amplitude. The experimental results showed that the addition of Eucommia ulmoides gum had an impact on the performance of the isolator, and the number of fatigue cycles would lead to the hardening of the Eucommia ulmoides gum isolator and changes in its static and dynamic performance. In the range of two million vibrations, the performance change of the isolator was significant in the early stage and then tended to be flat, indicating that the impact of fatigue on the performance of the isolator would not continue to persist. It is worth noting that the study found that the addition of 30% Eucommia ulmoides gum had the least impact on the performance of the isolator under fatigue. Therefore, for long-term use of Eucommia ulmoides gum isolators, attention should be paid to their fatigue characteristics to ensure their stability and reliability. Additionally, this study provides a reference for the design and application of Eucommia ulmoides gum isolators. In summary, this study provides important reference value for a deeper understanding of the fatigue characteristics of Eucommia ulmoides gum isolators and for ensuring their stable and reliable performance. .

关键词： Fatigue Characteristics Eucommia Rubber Vibration Isolators Static Performance Dynamic Performance

An environmentally sensitive zinc-selective two-photon NIR fluorescent turn-on probe and zinc sensing in stroke

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Journal of Pharmaceutical Analysis 2024年第4期14卷 578-584页

作者： junfeng Wang Qibing Liu Yingbo Li Yi Pang Department of Chemistry The University of AkronAkronOH 44325USA Gordon Center for Medical Imaging Department of RadiologyMassachusetts General HospitalHarvard Medical SchoolBostonMA 02114USA Department of Pharmacy The First Affiliated Hospital of Hainan Medical UniversityHaikou570100China Engineering Research Center of Tropical Medicine Ministry of EducationHainan Medical UniversityHaikou571199China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing100191China Maurice Morton Institute of Polymer Science The University of AkronAkronOH 44325USA

A two-photon near infrared(NIR)fluorescence turn-on sensor with high selectivity and sensitivity for Zn^(2+)detection has been *** sensor exhibits a large Stokes'shift(-300 nm)and can be excited from 900 to 1000 nm,with an emission wavelength of-785 nm,making it ideal for imaging in biological *** sensor's high selectivity for Zn^(2+)over other structurally similar cations,such as Cd^(2+),makes it a promising tool for monitoring zinc ion levels in biological *** the high concentration of zinc in thrombi,this sensor could provide a useful tool for in vivo thrombus imaging.

关键词： Near-infrared Molecular imaging Thrombus Stroke

Unit Commitment under the Environment of Wind Power and Large-Scale Bilateral Transactions

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Energy and Power Engineering 2017年第4期9卷 611-624页

作者： Fang Liu Yi Pan junfeng yang Zhiqiang Luo Lihua Liu China Electric Power Research Institute Haidian District Beijing China State Grid Corporation of China Xicheng District Beijing China

Bilateral electric power contract is settled based on contract output curve. This paper considered the bilateral transactions execution, new energy accommodation, power grid security and generation economy, considering the executive priority of different power components to establish a multi-objective coordination unit commitment model. Through an example to verify the effectiveness of the model in promoting wind power consumption, guaranteeing trade execution, and improving power generation efficiency, and analyzed the interactions to each other among the factors of wind power, trading and blocking. According to the results, when wind power causes reverse power flow in the congestion line, it will promote the implementation of contracts, the influence of wind power accommodation to trade execution should be analyzed combined with the grid block, the results can provide reference for wind power planning.

关键词： Bilateral Electric Power Contract Unit Commitment Wind Power Accommodation Transaction Execution Congestion

Effect of Interface Form on Creep Failure and Life of Dissimilar Metal Welds Involving Nickel-Based Weld Metal and Ferritic Base Metal

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 265-285页

作者： Xiaogang Li junfeng Nie Xin Wang Kejian Li Haiquan Zhang Institute of Nuclear and New Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of EducationTsinghua UniversityBeijing 100084China Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China

For dissimilar metal welds(DMWs)involving nickel-based weld metal(WM)and ferritic heat resistant steel base metal(BM)in power plants,there must be an interface between WM and BM,and this interface suffers mechanical and microstructure mismatches and is often the rupture location of premature *** this study,a new form of WM/BM interface form,namely double Y-type interface was designed for the *** behaviors and life of DMWs containing double Y-type interface and conventional I-type interface were compared by finite element analysis and creep tests,and creep failure mechanisms were investigated by stress-strain analysis and microstructure *** applying double Y-type interface instead of conventional I-type interface,failure location of DMW could be shifted from the WM/ferritic heat-affected zone(HAZ)interface into the ferritic HAZ or even the ferritic BM,and the failure mode change improved the creep life of *** interface premature failure of I-type interface DMW was related to the coupling effect of microstructure degradation,stress and strain concentrations,and oxide notch on the WM/HAZ *** creep failure of double Y-type interface DMW was the result of Type IV fracture due to the creep voids and micro-cracks on fine-grain boundaries in HAZ,which was a result of the matrix softening of HAZ and lack of precipitate pinning at fine-grain *** double Y-type interface form separated the stress and strain concentrations in DMW from the WM/HAZ interface,preventing the trigger effect of oxide notch on interface failure and inhibiting the interfacial microstructure *** is a novel scheme to prolong creep life and enhance reliability of DMW,by means of optimizing the interface form,decoupling the damage factors from WM/HAZ interface,and then changing the failure mechanism and shifting the failure location.

关键词： Dissimilar metal weld Nickel-based weld metal Ferritic heat resistant steel Interface Creep strain Microstructure Failure mechanism Creep life

图像处理中全变差正则化数据拟合问题算法回顾

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运筹学学报 2017年第4期21卷 69-83页

作者：杨俊锋南京大学数学系南京210093

全变差正则化数据拟合问题产生于许多图像处理任务,如图像去噪、去模糊、图像修复、磁共振成像、压缩图像感知等.近年来,求解此类问题的快速高效算法发展很快.以最小二乘、最小一乘等为例简要回顾求解此类问题的主要算法,并讨论一个全... 详细信息

全变差正则化数据拟合问题产生于许多图像处理任务,如图像去噪、去模糊、图像修复、磁共振成像、压缩图像感知等.近年来,求解此类问题的快速高效算法发展很快.以最小二乘、最小一乘等为例简要回顾求解此类问题的主要算法,并讨论一个全变差正则化非凸数据拟合模型在脉冲噪声图像去模糊问题中的应用.

关键词：全变差最小二乘最小一乘、图像处理收缩算子快速傅里叶变换梯度下降阈值算法分裂罚算法交替方向乘子法

创新课堂教学模式培养学生国际视野——跨文化混合同步网络课堂的实证研究

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中国电化教育 2015年第10期 33-38页

作者：杨俊锋杭州师范大学教育学院浙江杭州311121

慕课(MOOCs)的发展使我们看到了信息时代学习的新方式,网络技术的发展为促进国际化人才的培养提供了另一种可能。基于高校国际化人才培养的瓶颈,结合网络技术的最新发展,该文提出了"跨文化混合同步网络课堂"的概念,并开展了一个学期的... 详细信息

慕课(MOOCs)的发展使我们看到了信息时代学习的新方式,网络技术的发展为促进国际化人才的培养提供了另一种可能。基于高校国际化人才培养的瓶颈,结合网络技术的最新发展,该文提出了"跨文化混合同步网络课堂"的概念,并开展了一个学期的实践。结果表明:学生对跨文化混合同步网络课堂表现出了积极的兴趣,多数学生表示能开拓国际视野、提高英语能力;但实践中也存在各种问题,导致学生的学习效果并不够理想。最后该文指出了跨文化同步网络课堂可以从平台功能分析及模型架构、课堂的开展策略、课堂的基本特征、教师任务模型等四个方面开展研究,以便优化学生的学习体验,提升学习效能。

关键词：教学模式同步网络课堂跨文化国际视野混合学习

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互联网时代教师知识的发展路径

课程．教材．教法 2019年第2期39卷 120-125页

作者：杨俊锋杭州师范大学教育学院杭州311121

探讨互联网时代教师知识发展的基本路径,理解技术融入教师知识的基本规律,对提高教师信息化教学能力具有重要意义。互联网时代教师知识发展的基本路径包括:理解技术的教学支持性;使用技术解决教学问题;应用技术重新设计教学活动;运用技... 详细信息

探讨互联网时代教师知识发展的基本路径,理解技术融入教师知识的基本规律,对提高教师信息化教学能力具有重要意义。互联网时代教师知识发展的基本路径包括:理解技术的教学支持性;使用技术解决教学问题;应用技术重新设计教学活动;运用技术创新教学模式。

关键词：教师知识 PCK 发展路径

低温烧结Bi_2MoO_6-Bi_2Mo_2O_9陶瓷的微波介电性能

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硅酸盐学报 2016年第12期44卷 1700-1705页

作者：杨俊锋凌志远华南理工大学材料科学与工程学院广州510640

采用氧化物固相反应法制备x≤30%(质量分数)的不同xBi_2MoO_6-(1-x)Bi_2Mo_2O_9介质陶瓷材料,研究了Bi_2MoO_6掺入对Bi_2Mo_2O_9晶相结构、显微形貌和介电性能的影响。结果表明:烧结后陶瓷均为Bi_2MoO_6正交和Bi_2Mo_2O_9单斜两相混合,B... 详细信息

采用氧化物固相反应法制备x≤30%(质量分数)的不同xBi_2MoO_6-(1-x)Bi_2Mo_2O_9介质陶瓷材料,研究了Bi_2MoO_6掺入对Bi_2Mo_2O_9晶相结构、显微形貌和介电性能的影响。结果表明:烧结后陶瓷均为Bi_2MoO_6正交和Bi_2Mo_2O_9单斜两相混合,Bi_2MoO_6加入量对晶体结构和晶粒尺寸有明显影响;随着x的增大,xBi_2MoO_6-(1-x)Bi_2Mo_2O_9陶瓷的相对介电常数(ε_r)、品质因素(Qf)和谐振频率温度系数(τ_f)减小。0.3Bi_2MoO_6-0.7Bi_2Mo_2O_9在640℃空气下烧结2h,谐振频率7.72 GHz、ε_r=30.2、Qf=10 725 GHz、τ_f=1.6×10^(-6)/℃,具有优良的微波介电性能。

关键词：介质陶瓷钼酸铋低温烧结微波介电性能