检索结果-南通市图书馆

Flooding 1990s along the Yangtze River, has it concern of global warming?

Journal of Geographical Sciences 2001年第1期11卷 43-52页

作者： GONG Dao-yi1, ZHU Jin-hong2, WANG Shao-wu2 (1. key Laboratory of Environmental Change and Natural Disaster, Institute of Resources Science, Beijing Normal University, Beijing 100875, China 2. Department of Geophysics, Peking University, Beijing 100871, key Laboratory of Environmental Change and Natural Disaster Institute of Resources Science Beijing Normal University Beijing China Department of Geophysics Peking University Beijing China

There were a series of severe floods along the middle to lower reaches of the Yangtze River (Changjiang River) in China during the 1990s. The extensive summer (june, July and August) precipitation is mostly responsible for the flooding. The summer rainfall in the 1980s and the 1990s is much higher than that in the previous 3 decades. The means for 1990–1999 is +87.62 mm above normal, marked the 1990s the wettest decade since the 1950s. Six stations with a time span of 1880–1999 are selected to establish century-long rainfall series. This series also shows that the 1990s is the wettest decade during the last 120 years. In the wettest 12 years, four occurred in the 1990s (1991, 1996, 1998 and 1999). Both global and China’s temperature show there is a relative lower air temperature during the 1960–1970s, and a rapid warming in the 1980–1990s. Comparisons of rainfall between 1960–1979 and 1980–1999 show there are dramatic changes. In the cold period 1960–1979, the summer rainfall along the Yangtze River is 3.8 % to 4.7 % below the normal, during the warm period 1980–1999, over 8.4 % to 18.2 % of summer rainfall occurs. Over the whole eastern China, the summer rainfall shows opposite spatial patterns from the 1960–1970s to 1980–1990s. The consistent trend toward more rainfall with global warming is also presented by the greenhouse scenario modeling. A millennial Drought/flood Index for the middle to lower reaches of the Yangtze River showed that although the surplus summer rainfall in the 1990s is the severest during the past 150 years, it is not outstanding in the context of past millennium. Power spectra of the Drought/flood Index show significant interdecadal periods at 33.3 and 11.8 years. Thus, both the natural interdecadal variations and the global warming may play important roles in the frequent floods witnessed during the last two decades.

关键词： summer rainfall Yangtze River global warming interdecadal variation

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高校图书馆基于学科映射的数据资源增值服务

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大学图书馆学报 2023年第3期41卷 19-27,18页

作者：张俊娥陈建龙北京大学图书馆北京100871

介绍了对图书馆文献分类与高校学科体系映射关系的研究及其应用服务实践,提出了以高校各学科的“培养目标、专业范围和知识体系/课程”的文本内容为基础,析出其所涉及的主题词,利用图书馆按主题分类的编目专业优势,由专业编目人员通过... 详细信息

介绍了对图书馆文献分类与高校学科体系映射关系的研究及其应用服务实践,提出了以高校各学科的“培养目标、专业范围和知识体系/课程”的文本内容为基础,析出其所涉及的主题词,利用图书馆按主题分类的编目专业优势,由专业编目人员通过主题词分配《中国图书馆分类法》分类号,把高校学科体系与《中国图书馆分类法》体系关联起来,进而建立了分层分级的分类文献资源与高校学科的映射关系模型,并提出了高校图书馆基于学科映射更好地服务于学科专业建设的数据服务路线。

关键词：文献分类学科专业学科映射数据增值服务高校图书馆

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计及攻击损益的跨空间连锁故障选择排序方法

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电网技术 2018年第12期42卷 3926-3934页

作者：王宇飞李俊娥邱健刘艳丽空天信息安全与可信计算教育部重点实验室(武汉大学国家网络安全学院) 湖北省武汉市430072 全球能源互联网研究院有限公司北京市昌平区102209 电力规划设计总院北京市西城区100120 智能电网教育部重点实验室(天津大学) 天津市南开区300072

为了揭示电网信息物理系统(power grid cyber-physical systems,PGCPS)中由信息攻击引发跨空间连锁故障的演化过程及爆发可能性,从攻击者视角提出了一种基于攻击损益原则的跨空间连锁故障选择排序方法。首先,分析攻击者在此类故障演化... 详细信息

为了揭示电网信息物理系统(power grid cyber-physical systems,PGCPS)中由信息攻击引发跨空间连锁故障的演化过程及爆发可能性,从攻击者视角提出了一种基于攻击损益原则的跨空间连锁故障选择排序方法。首先,分析攻击者在此类故障演化过程中的推动作用,构建故障演化过程的有向攻击图,将此类故障抽象为攻击路径;进而,综合考虑攻击代价与攻击收益等因素,提出各攻击路径的攻击损益值计算方法,并探讨不同条件下攻击者对各攻击路径的倾向性选择排序,以推断不同跨空间连锁故障爆发的可能性;最后,在基于CEPRI-36节点的PGCPS仿真环境中,模拟攻击者对各类跨空间连锁故障的倾向性选择并予以仿真验证。

关键词：电网信息物理系统信息攻击跨空间连锁故障攻击损益选择排序

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基于模糊测试的GOOSE协议解析漏洞挖掘方法

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中国电力 2022年第4期55卷 33-43页

作者：刘林彬苗泉强李俊娥空天信息安全与可信计算教育部重点实验室(武汉大学国家网络安全学院) 湖北武汉430072 光电对抗测试评估技术重点实验室河南洛阳471000

现有工控协议模糊测试方法未考虑嵌入式终端系统特点,且对未采用传输控制协议/网际协议(TCP/IP)的工控协议研究较少。基于模糊测试提出一种通用面向对象变电站事件(GOOSE)协议解析漏洞挖掘方法。使用变异方式构造测试用例,给出基于GOOS... 详细信息

现有工控协议模糊测试方法未考虑嵌入式终端系统特点,且对未采用传输控制协议/网际协议(TCP/IP)的工控协议研究较少。基于模糊测试提出一种通用面向对象变电站事件(GOOSE)协议解析漏洞挖掘方法。使用变异方式构造测试用例,给出基于GOOSE报文字段类型、抽象语法标记1(ASN.1)编码方式和比特翻转的3类变异策略;提出基于心跳报文和系统运行信息的终端异常监测方法。设计所提方法的实施系统架构和测试流程,在智能变电站实验室环境中,对某厂家嵌入式终端进行测试,发现2个未公开的GOOSE协议解析漏洞,验证所提方法的有效性,提出防范基于此类漏洞的畸形报文攻击的建议。

关键词：模糊测试 GOOSE协议电网嵌入式终端漏洞挖掘畸形报文攻击

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叶酸受体阳性肿瘤靶向显像剂同型99Tcm和188Re标记的叶酸-甘氨酸-甘氨酸-半胱氨酸-谷氨酸的临床前研究

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中华核医学与分子影像杂志 2017年第7期37卷 444-444页

作者：唐军 Woo Hyoung Kim Chang Guhn Kim Myoung Hyoun Kim Dae-Weung Kim Cho Rong Park Ji Yong Park Yun-Sang lee Hyewon Youn Keon Wook Kang Jae Min Jeong june-key Chung 苏州大学附属第二医院核医学科 Department of Nuclear Medicine Seoul National University Hospital Department of Nuclear Medicine Institute of Wonkwang Medical ScienceWonkwang University School of Medicine

目的制备同型的~(（99）Tcm和~(（188）Re标记的叶酸-甘氨酸-甘氨酸-半胱氨酸-谷氨酸（叶酸-GGCE）,并通过小鼠肿瘤模型评价其用于叶酸受体（FR）靶向分子显像的可行性。方法采用固相肽合成法合成叶酸-GGCE,并用99Tcm或188Re标记。放化... 详细信息

目的制备同型的~(（99）Tcm和~(（188）Re标记的叶酸-甘氨酸-甘氨酸-半胱氨酸-谷氨酸（叶酸-GGCE）,并通过小鼠肿瘤模型评价其用于叶酸受体（FR）靶向分子显像的可行性。方法采用固相肽合成法合成叶酸-GGCE,并用99Tcm或188Re标记。放化纯测定采用放射性高效液相色谱法。99Tcm-叶酸-GGCE的生物分布研究在同时注射或不注射过量的游离叶酸的情况下完成,小鼠肿瘤模型分别为荷FR阳性的KB细胞模型和荷FR阴性的HT1080细胞模型。188Re-叶酸-GGCE的生物分布研究在荷KB细胞小鼠肿瘤模型上完成。静脉注射99Tcm-叶酸-GGCE后,采集2种小鼠肿瘤模型的系列平面图像。小鼠肿瘤模型注射99Tcm-叶酸-GGCE或188Re-叶酸-GGCE（同时注射或不注射过量的游离叶酸）后,进行系列microSPECT/CT图像采集。结果99Tcm和188Re标记的叶酸-GGCE的标记率和标记后4 h内的放化纯均>95%。荷KB细胞模型在注射99Tcm-叶酸-GGCE后1、2、4 h,其肿瘤组织的放射性摄取值分别为16.4、23.2和17.6%ID/g,如果同时注射过量的叶酸,肿瘤组织的摄取可被抑制97.4%。注射后4 h,肿瘤与血液、肝、肺、肌肉和肾的T/NT比值分别是54.3、25.2、38.3、97.8和0.3。荷KB细胞模型在注射188Re-叶酸-GGCE后2、4、8、16 h,其肿瘤组织的放射性摄取值分别为17.4、21.7、24.1和15.6%ID/g。注射后8 h,肿瘤与血液、肝、肺、肌肉和肾的T/NT比值分别是126.8、21.9、54.8、80.3和0.4。注射99Tcm或188Re标记的叶酸-GGCE后,系列平面图像和microSPECT/CT图像均见KB细胞肿瘤组织的放射性摄取较高,肿瘤显像清晰。肿瘤对显像剂的摄取在同时注射过量叶酸时可被完全抑制。结论同型99Tcm和188Re标记的叶酸-GGCE可被FR阳性肿瘤高摄取,且T/NT比值较高。2种显像剂均具有良好的靶向能力,在FR阳性肿瘤的诊断和疗效观察中有一定的应用价值。

关键词：叶酸受体肿瘤 99Tcm 188Re SPECT/CT

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Elemental composition of aerosols collected in the glacier area on Nyainqêntanglha Range, Tibetan Plateau, during summer monsoon season

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Chinese Science Bulletin 2007年第24期52卷 3436-3442页

作者： LI ChaoLiu1,2, KANG ShiChang1,3 & CONG ZhiYuan1,2 1 Nam Co Monitoring and Research Station for Multisphere Interactions, Institute of Tibetan Plateau Research, CAS, Beijing 100085, China 2 Graduate University of Chinese Academy of Sciences, Beijing 100039, China 3 State key Laboratory of Cryospheric Sciences, CAS, Lanzhou 730000, China Nam Co Monitoring and Research Station for Multisphere Interactions Institute of Tibetan Plateau Research CAS Beijing China Graduate University of Chinese Academy of Sciences Beijing China State key Laboratory of Cryospheric Sciences CAS Lanzhou China

In order to investigate the elemental composition in atmospheric aerosols and its sources in the glacier area over the Tibetan Plateau (TP), seven totally suspended particle samples were collected continuously at the col of the Zhadang glacier (30°28′N,90°39′E,5800 m a.s.l.), Nyainqêntanglha Range, southern TP, from june to October 2006. Twenty-seven elements (Li, Be, B, Na, Mg, Al, K, Ca, Sc, Ti, V, Fe, Mn, Zn, Ga, As, Rb, Sr, Y, Cd, Cs, Ba, Tl, Pb, Bi, Th, U) were analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The result indicates that the concentrations of most elements (especially crustal elements) are lower than values at the Nam Co Station during the same period of 2005, and also much lower than other sites in the TP such as Wudaoliang and Waliguan. This suggests that elemental compositions of aerosols in the Zhadang glacier area may represent the background levels of the middle/upper troposphere over the TP. Crustal enrichment factors (EFs) reveal that several elements (e.g. B, Zn, As, Cd, Pb and Bi) may have anthropogenic sources. The southern TP is mainly influenced by the summer Indian monsoon during the sampling period. Backward air mass trajectory analysis suggests that air masses in the region may originate from South Asia. Therefore, anthropogenic pollutants from South Asia may be transported by the summer Indian monsoon to the region which clearly affects the atmospheric environment in the southern TP during the summer monsoon season.

关键词：元素组成浮质冰河西藏夏季

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Western Indian Ocean SST signal and anomalous Antarctic sea-ice concentration variation

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Acta Oceanologica Sinica 2011年第2期30卷 9-13页

作者： LIU Na ZHANG Zhanhai CHEN Hongxia LIN Lina First Institute of Oceanography State Oceanic Administration Qingdao 266061 China key Laboratory for Polar Science Polar Research Institute of China Shanghai 200136 ChinaReceived 13 June 2010 accepted 2 December 2010

Teleconnection between El Nino/La Nina-Southern Oscillation （ENSO） phenomenon and anomalous Antarctic sea-ice variation has been studied *** this study,impacts of sea surface temperature in the Indian Ocean on Antarctic sea-ice change were investigated during Janaury 1979 and October *** on previous research results,sea areas in the western Indian Ocean （WIO;50°–70°E,10 °–20 °S） are selected for the *** variables showed 1-10 year interannual timescales by Fast Founer Tranaform （FFT） *** show that i） strong WIO signals emerged in the anomalous changes of Antarctic sea-ice concentration;ii） significant positive correlations occurred around the Antarctic Peninsula,Ross Sea and its northwest peripheral sea region iii） negative correlation occurred in the Indian Ocean section of the Southern Ocean,Amundsen Seas,and the sea area over northern Ross Sea;and iv） the atmospheric anomalies associated with the WIO including wind,meridional heat flux,and surface air temperature over southern high latitudes were the possible factors for the teleconnection.

关键词： Antarctic sea-ice western Indian Ocean sea surface temperature

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Sorafenib in treatment of patients with advanced hepatocellular carcinoma:a systematic review

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Hepatobiliary & Pancreatic Diseases International 2012年第5期11卷 458-466页

作者： Xin Zhang, Xin-Rong Yang, Xiao-Wu Huang, Wei-Min Wang, Ruo-Yu Shi, Yang Xu, Zheng Wang, Shuang-Jian Qiu, Jia Fan ,Jian Zhou Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai key Laboratory for Organ Transplantation, Shanghai 200032, China,Institute of Biomedical Sciences, Fudan University, Shanghai 200032, China Liver Cancer Institute Zhongshan Hospital Fudan University and Shanghai Key Laboratory for Organ Transplantation Shanghai 200032 Shanghai China Institute of Biomedical Sciences Fudan University Shanghai 200032 Shanghai China

BACKGROUND: Sorafenib has become the standard first-line treatment for patients with advanced hepatocellular carcinoma (HCC). This study aimed to assess the efficacy and safety of sorafenib in advanced HCC patients and explore its true value for specific subgroups. DATA SOURCES: A computer-based systematic search from January 2005 to june 2011 with 'sorafenib' and 'advanced hepatocellular carcinoma' as search terms was performed for possible clinical trials. Hazard ratios (HR) and their 95% confidence intervals (CI) for overall survival (OS) and time to progression (TTP), rates of partial response (PR), rates of toxicity effects, and details of subgroup analysis were extracted. Meta-analyses were done using the software Review Manager (version 5.0). RESULTS: Six trials with 1164 patients were included. Based on three randomized controlled trials, the pooled HR (sorafenib/ placebo) was 0.66 for OS (95% CI: 0.56-0.78; P<0.00001) and 0.57 for TTP (95% CI: 0.47-0.68; P<0.00001). The pooled odds ratio (OR) for PR was 2.96 (95% CI: 0.96-9.15; P=0.06). For three single-arm trials, the pooled HR was 0.69 for OS (95% CI: 0.56-0.84; P=0.0002) and 0.64 for TTP (95% CI: 0.52-0.78; P<0.00001). The pooled OR for PR in three single-arm trials was 3.56 (95% CI: 1.22-10.39; P=0.02). Subgroup analysis indicated that sorafenib was less effective in patients with extrahepatic spread (with: P=0.13 vs without: P<0.0001), with normal alpha-fetoprotein level (AFP) (P=0.15 vs elevated: P=0.0006), and with elevated level of serum bilirubin (P=0.06 vs normal: P=0.0009). Sorafenib-based therapy significantly increased the risk of grade 3/4 hand-foot skin reaction, diarrhea, fatigue, and rash/***: Sorafenib-based therapy benefits advanced HCC patients. Meanwhile, sorafenib is less effective for patients with extrahepatic spread, with normal AFP level and with elevated level of bilirubin.

关键词： advanced hepatocellular carcinoma sorafenib systematic review

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Characteristics of U-pattern distribution of high-concentration 210Pb in surface air at central Guizhou,China

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Science Bulletin 2005年第16期 80-85页

作者： S.N.lee NY 10014-4811 Environmental Measurements Laboratory Department of Homeland Security USA

A better understanding of the variation of 210Pb concentrations in the surface air is the key to trace lake sedimentation and catchment erosion, to establish and vali-date the global diffusion model of contaminants, and to as-sess the impact of natural radiation on the ecological system. Basing on the study progresses of the sedimentation, the at-mospheric model and the unique environmental background in the Yunnan-Guizhou Plateau, and starting from December 20, 2001, we made use of a 500 NE Type aerosol sampler to collect filter samples, once a week in the past consecutive two years, in the surface air at Mt. Guanfeng, Guiyang City, China. Synchronous detailed γ -energy spectrometric obser-vations of 210Pb concentrations at both Chinese and U.S. laboratories have shown that the average monthly 210Pb concentration displays a regular U-patterns distribution of annual variations, with high values appearing in winter and low values in late spring and summer. The average annual 210Pb concentrations are estimated to be 2.77±0.63 mBq/m3, about 4 times the average maximum concentrations reported from quite a number of monitoring stations throughout the world. The possible factors affecting the sources of 210Pb in the surface air in the central part of Guizhou Province are: Release of 222Rn from the U-Ra series enriched in the soils; chemical weathering of carbonate rocks; the exploitation, processing and utilization of coal and phosphorous resources. The principal factor controlling the high 210Pb concentrations in the surface air in the central Guizhou and their annual U-pattern distribution is the release of 222Rn. The average monthly 210Pb concentrations show a good negative power- function relationship with increasing precipitation and also show a good negative linear-function relationship with the rise of air temperature in month grouping. Group No.1 (june to November) reflects a relatively low release of 222Rn from soils in relatively high temperature seasons; Group

关键词： 210Pb concentration in surface air U-pattern in annual distribution central Guizhou.

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Measurement of the current and spectral analysis on the continental shelf in the East China Sea

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Acta Oceanologica Sinica 2004年第2期23卷 201-212页

作者： LIUYonggang YUANYaochu LIUCho-Teng CHENHong CollegeofMarineScience UniversityofSouthFloridaUSA SecondInstituteofOceanography StateOceanicAdministrationHangzhou310012China InstituteofOceanography TaiwanUniversityTaipeiChina

Direct measurements of current velocity and water temperature were undertaken at the mooring Sta. M (125°29.38' N, 31°49.70' E) on the continental shelf area in the East China Sea in june 1999 by R/V Xiangyanghong 14. The relationship between various time series of oceanic fluctuations is calculated by spectral analysis. The major results are as follows: (1) an average (u,v) of (6.9,-3.0 cm/s) at the 30 m depth is obtained during the 9-day observation, and that at the 45 m depth is (3.7,-1.1 cm/s), i. e., the mean flows are southeastward at both the 30 and 45 m depths;the currents become stronger gradually during the observation period; this may be mainly attributed to the transition of the tidal currents from neap to spring; (2)semidiurnal fluctuation is the most dominant in the current fluctuations, and rotates mainly clockwise; in the next place, there is also diurnal fluctuation;the local inertial period is close to the period of diurnal fluctuation, and an inertial motion is clockwise; thus, local inertial motion combines with diurnal fluctuation, and makes the spectral peaks in clockwise components much higher than those in counterclockwise ones; except for the fluctuations of above main periods, there is also the peak at 3 d period for counterclockwise compo-nents in the upper and lower layers; (3) the calculation of cross spectra between two time series of current velocities at the 30 and 45 m depths shows that both the current fluctuations at the 30 and 45 m depths are much alike, i. e., they are synchro; this shows that the flow field here is rather vertically homogeneous; (4)power spectra of tempera-ture time series at both the 30 and 45 m depths show that the semidiurnal peak is the most predominant, and the second highest peak is the diurnal period; besides spectral peaks at above periods, there are also obvious spectral peaks at 6.8 h and 2 d; (5)plots of temperature time series at 16 , 30 , 35 , 45 and 50 m depths show that the temporal variations of

关键词： East China Sea current on the continental shelf measurements of current by the mooring system

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