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Experimental Investigation on Noise of Cavitation Nozzle and Its Chaotic Behaviour

Chinese Journal of Mechanical Engineering 2013年第4期26卷 758-762页

作者： ZHANG Fenghua LIU Haifeng xu junchao TANG Chuanlin School of Mechanical Engineering Hunan University of Technology

The researches of cavitation noise mainly focus on the incipiency and developing of cavitation to prevent the cavititation erosion in the hydraulic machinery, while there is few report about the collapse strength of cavitation bubbles produced by water jet through the cavitation nozzle to utilize efficiently the collapse energy of cavitation bubbles. The cavitation noise signals are collected with hydrophones for the cavitation nozzle and general nozzle at the target position and the nozzle exit separately in the conditions of different standoff distance. The features of signal’s frequency spectrum and power spectrum are analyzed for various nozzles by way of classical methods. Meanwhile, based on chaotic theory, phase space reconstruction is processed and the maximum Lyapunov index is calculated separately for each cavitation signal’s time series. The results of chaotic analysis are compared with the one of conventional analysis. The analyzed data show that there are the marked differences at the spectrum between the cavitation nozzle and general nozzle at the target position while the standoff distance is 35 mm, which mainly displays at the high frequency segment (60-120 kHz). The maximum Lyapunov index calculated appear at standoff distance 35 mm, which is an optimum standoff distance for the most bubbles to collapse at the target. At the nozzle exit, the noise signal of cavitation nozzle is different from the general nozzle, which also displays at the high frequency segment. The results demonstrate that the water jet modulated by the cavitation nozzle can produce effectually cavitation, and at the target position the amplitude and energy of noise spectrum in high frequency segment for cavitation nozzle are higher than conventional nozzle and the Lyapunov index of cavitation nozzle is larger than conventional nozzle as the standoff distance is less than 55 mm. The proposed research reveals that the cavitation noise produced by collapse of cavitation bubbles attri

关键词： cavitation water jet nozzle Lyapunov exponent chaos

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Recent progress in Michael addition-based fluorescent probes for sulfur dioxide and its derivatives

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Chinese Chemical Letters 2018年第10期29卷 1456-1464页

作者： junchao xu Houqun Yuan Lintao Zeng Guangming Bao Institute of Veterinary Drug Jiangxi Agricultural University/Jiangxi Provincial Key Laboratory for Animal Health School of Chemistry and Chemical Engineering Tianjin University of Technology

Sulfur dioxide（SO_2） is a harmful environmental pollutant. Inhaled SO_2 can be rapidly hydrated into its derivatives, bisulfite（HSO_3^-） and sulfite（SO_3^（2-））. SO_2 derivatives are well known as preservatives and antioxidants, which are used in food and beverages to prevent oxidation and bacterial growth. Although SO_2 can be endogenously generated in mammals and exhibits unique bioactivities in regulating cardiovascular function, excessive SO_2 and its derivatives have toxic effects on humans and animals for triggering adverse reactions and diseases. A large number of fluorescent probes for SO_2 and its derivatives have been designed and reported due to their high sensitivity and selectivity, high temporal and spatial resolution, non-invasive and non-destructive detection as well as real-time visualization in situ. In this review, we have summarized the recent progress of Michael addition-based fluorescent probes for SO_2 and its derivatives. These probes are categorized and concluded according to the different α,β-unsaturated compounds（i.e., Michael acceptors）. The design strategies, sensing performances, detection mechanisms and applications of these probes are discussed in detailed. Finally, a general overview about the design of probes for SO_2 and its derivatives is provided, which will facilitate the development of ideal probes for SO_2 and its derivatives.

关键词： Fluorescent probes Michael addition Sulfur dioxide Bisulfite Sulfite Application

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Molecular dynamics study of water molecules nucleation for fine particle removal:Effects of wettability and aggregation modes and comparison with experiment Author links open overlay panel

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Particuology 2024年第8期91卷 106-117页

作者： junchao xu Zhipeng Zhang Li Lv Yunfei Zhang Yiming Xie Huaqiang Chu School of Energy and Environment Anhui University of TechnologyMaanshan243002China College of Mechanical and Electrical Engineering China Jiliang UniversityHangzhou310018China

Water vapor nucleation on particle's surface plays an important role in dust removal,cloud formation,and particle ***,the selectivity of nucleation sites and the nucleation characteristic of water molecule on the particle's surface are still unclear,especially for the aggregated *** this paper,the effects of particle wettability and aggregation modes on the selectivity of nucleation sites and the nucleation characteristics were investigated using molecular dynamics *** results were compared with our earlier experimental *** illustrates how the contact angle of clusters,the growth velocity,and the growth duration are all influenced by the interaction coefficient between water and ***,the nucleation sites of water molecules on the particle aggregation surface exhibit a definite *** primary indicator of this selectivity is the preferential nucleation of water molecules at the interfaces of linear chain aggregation particles,at the inner side of non-linear chain aggregation particles,and at the centers of ring *** results are in good agreement with our previous experimental *** significantly,additional research has revealed that subcritical-size clusters typically aggregate on two-particle surfaces spacing when the spacing smaller than the critical cluster size.

关键词： Heterogeneous nucleation Water molecule Wettability Aggregation modes Molecule dynamics

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Anti-lymphangiogenesis for boosting drug accumulation in tumors

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2161-2175页

作者： Chunling Wang junchao xu Xiaoyu Cheng Ge Sun Fenfen Li Guangjun Nie Yinlong Zhang CAS Key Laboratory for Biomedical Effects of Nanomaterials&Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China Sino-Danish College University of Chinese Academy of SciencesBeijing 100190China Sino-Danish Center for Education and Research Beijing 100190China Department of Bioengineering University of PennsylvaniaPhiladelphiaPA 19104USA School of Nanoscience and Engineering University of Chinese Academy of SciencesBeijing 100049China

The inadequate tumor accumulation of anti-cancer agents is a major shortcoming of current therapeutic drugs and remains an even more significant concern in the clinical prospects for *** strategies aiming at regulating the intratumoral permeability of therapeutic drugs have been explored in preclinical studies,with a primary focus on vascular regulation and stromal ***,these methods may trigger or facilitate tumor metastasis as a ***,there is an urgent need for innovative strategies that boost intratumoral drug accumulation without compromising treatment *** another important factor affecting drug tumor accumulation besides vasculature and stroma,the impact of tumor-associated lymphatic vessels(LVs)has not been widely *** the current research,we verified that anlotinib,a tyrosine kinase inhibitor with anti-lymphangiogenesis activity,and SAR131675,a selective VEGFR-3 inhibitor,effectively decreased the density of tumor lymphatic vessels in mouse cancer models,further enhancing drug accumulation in tumor *** combining anlotinib with therapeutic drugs,including doxorubicin(Dox),liposomal doxorubicin(Lip-Dox),and anti-PD-L1 antibody,we observed improved anti-tumor efficacy in comparison with monotherapy ***,this strategy significantly reduced tumor metastasis and elicited stronger anti-tumor immune *** work describes a new,clinically transferrable approach to augmenting intratumoral drug accumulation,which shows great potential to address the current,unsatisfactory efficacies of therapeutic drugs without introducing metastatic risk.

关键词： drugs angiogenesis metastasis

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Correction:Anti-lymphangiogenesis for boosting drug accumulation in tumors

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Signal Transduction and Targeted Therapy 2024年第7期9卷 3141-3142页

作者： Chunling Wang junchao xu Xiaoyu Cheng Ge Sun Fenfen Li Guangjun Nie Yinlong Zhang National Center for Nanoscience and Technology CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety CAS Center for Excellence in Nanoscience Beijing China (GRID:grid.419265.d) (ISNI:0000 0004 1806 6075) University of Chinese Academy of Sciences Sino-Danish College Beijing China (GRID:grid.410726.6) (ISNI:0000 0004 1797 8419) Sino-Danish Center for Education and Research Beijing China (GRID:grid.484648.2) (ISNI:0000 0004 0480 4559) National Center for Nanoscience and Technology CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety CAS Center for Excellence in Nanoscience Beijing China (GRID:grid.419265.d) (ISNI:0000 0004 1806 6075) University of Pennsylvania Department of Bioengineering Philadelphia USA (GRID:grid.25879.31) (ISNI:0000 0004 1936 8972) University of Chinese Academy of Sciences Sino-Danish College Beijing China (GRID:grid.410726.6) (ISNI:0000 0004 1797 8419) University of Chinese Academy of Sciences School of Nanoscience and Engineering Beijing China (GRID:grid.410726.6) (ISNI:0000 0004 1797 8419) National Center for Nanoscience and Technology CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety CAS Center for Excellence in Nanoscience Beijing China (GRID:grid.419265.d) (ISNI:0000 0004 1806 6075)

Correction to:Signal Transduction and Targeted Therapy https://***/10.1038/s41392-024-01794-4,published online 15 April 2024 After the article was published online,1 the authors noticed one inadvertent mistake in Supplementary *** image of lung H&E in the Lip-Dox group was repeatedly inserted as the image of Dox group by mistake during the preparation of the *** correct figure was provided as *** correction did not affect any of our results or discussion presented in the original *** apologize for this inadvertent *** original article has been corrected.

关键词： lung boosting repeatedly

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润湿剂促进细颗粒在水汽条件下长大的实验研究

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东南大学学报（自然科学版） 2017年第1期47卷 67-72页

作者：徐俊超于燕张军钟辉东南大学能源热转换及其过程测控教育部重点实验室南京210096

为了研究润湿剂对细颗粒表面润湿性能的改善效果及其促进细颗粒在水汽条件下的长大特性,对添加润湿剂Tween20作用下的细颗粒表面润湿性能进行了测量,并通过在热水中添加润湿剂研究了Tween20对细颗粒在水汽条件下长大的影响.结果表明:Twe... 详细信息

为了研究润湿剂对细颗粒表面润湿性能的改善效果及其促进细颗粒在水汽条件下的长大特性,对添加润湿剂Tween20作用下的细颗粒表面润湿性能进行了测量,并通过在热水中添加润湿剂研究了Tween20对细颗粒在水汽条件下长大的影响.结果表明:Tween20可以有效改善细颗粒表面的润湿性能并促进细颗粒的长大,同时Tween20的添加方式和添加量对促进细颗粒的长大效果都有一定的影响;Tween20的添加浓度不同对细颗粒的长大促进作用机制也不同,在Tw een20浓度10~30 g/L的范围内,添加润湿剂有利于细颗粒的长大,但当Tw een20的添加浓度超过30 g/L后,添加润湿剂虽然可以提高颗粒长大的最终直径,但是润湿剂的增加并不利于小粒径段(<1μm)细颗粒的长大,Tween20的浓度为30 g/L时对细颗粒的长大促进效果最优.因此,在应用润湿剂促进细颗粒物长大并脱除时,适量地添加润湿剂才能达到最佳的促进效果.

关键词：润湿剂细颗粒水汽长大

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高铁站场下地下空间结构逆作施工变形分析

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城市轨道交通研究 2015年第1期18卷 49-52,66页

作者：许俊超中铁第四勘察设计院集团有限公司武汉高级工程师430063

随着城市轨道交通和高速铁路的大量建设,两者之间的交叉影响越来越多。以上海西站地下南北通道工程为背景,考虑高速铁路列车荷载特点,并将此荷载施加到地下空间结构逆作施工的三维有限元模型中,通过三维有限元数值模拟及实测数据的对比... 详细信息

随着城市轨道交通和高速铁路的大量建设,两者之间的交叉影响越来越多。以上海西站地下南北通道工程为背景,考虑高速铁路列车荷载特点,并将此荷载施加到地下空间结构逆作施工的三维有限元模型中,通过三维有限元数值模拟及实测数据的对比分析,从而得到地下空间结构及高速铁路路基的变形规律。

关键词：高速铁路地下空间结构逆作施工数值模拟

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液滴在燃煤细颗粒表面凝结的长大动力学特性

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东南大学学报（自然科学版） 2017年第3期47卷 506-512页

作者：徐俊超于燕张军钟辉东南大学能源热转换及其过程测控教育部重点实验室南京210096

为了研究液滴在燃煤细颗粒表面的长大动力学特性,实验测量了水在不同燃煤细颗粒表面的接触角θ,考虑液滴在燃煤细颗粒表面长大的2种作用机制:细颗粒表面水汽的直接扩散凝结和颗粒表面吸附水扩散凝结,对燃煤细颗粒表面单液滴的长大动力... 详细信息

为了研究液滴在燃煤细颗粒表面的长大动力学特性,实验测量了水在不同燃煤细颗粒表面的接触角θ,考虑液滴在燃煤细颗粒表面长大的2种作用机制:细颗粒表面水汽的直接扩散凝结和颗粒表面吸附水扩散凝结,对燃煤细颗粒表面单液滴的长大动力学进行了研究.数值讨论了燃煤细颗粒粒径、蒸汽过饱和度、蒸汽温度、液滴半径和颗粒表面润湿性对单液滴在燃煤细颗粒表面长大速率的影响.结果表明:当颗粒粒径小于0.5μm时,液滴的长大速率随着燃煤细颗粒的增大迅速增大,当粒径大于0.5μm时,长大速率随着粒径的增大缓慢增长;液滴的长大速率随着过饱和度上升呈指数倍增长,但是随着蒸汽温度的上升而呈现下降的趋势;液滴的长大速率开始随着液滴半径的增大而急剧下降,长大到某一半径后下降的趋势变缓;当0≤cosθ≤0.8时,长大速率随着润湿角余弦值的增大而平缓地增大,当0.8≤cosθ≤1时,长大速率会随着润湿角余弦值的增大而急剧增大.

关键词：液滴燃煤细颗粒长大动力学

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富水软土地区地铁装配叠合整体式地下车站设计关键技术研究

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城市轨道交通研究 2022年第7期25卷 115-119页

作者：许俊超中铁第四勘察设计院集团有限公司武汉430063

对地铁装配叠合整体式地下车站整体及各构件在不同工况下的受力性能、结构整体抗震性能进行计算,对关键节点的力学性能、防水关键技术等进行研究,研发出一种适用于富水软土地区地铁的装配叠合整体式地下车站设计方案,并针对其重点和难... 详细信息

对地铁装配叠合整体式地下车站整体及各构件在不同工况下的受力性能、结构整体抗震性能进行计算,对关键节点的力学性能、防水关键技术等进行研究,研发出一种适用于富水软土地区地铁的装配叠合整体式地下车站设计方案,并针对其重点和难题提出了有针对性和可操作性的关键技术措施。该方案在无锡至江阴城际轨道交通工程的南门站得以应用,形成了从装配方案体系设计、预制构件设计及产业化生产、施工智能化管理、设备研发应用的全流程关键技术,对于缩短施工工期、节约资源、提升劳动生产效率、促进建筑产业转型升级等具有促进作用。

关键词：地铁地下车站装配叠合整体式富水软土地区关键技术

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生长管中过饱和度在不同构建方式下的分布特性

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东南大学学报（自然科学版） 2016年第4期46卷 733-738页

作者：于燕徐俊超张军孟强钟辉东南大学太阳能技术研究中心南京210096

为了研究水汽相变中不同构建方式形成的细颗粒长大所需的过饱和环境,利用变物性参数传热传质模型对生长管中过饱和度水平进行了预测,并评价了2种过饱和构建方式:低温饱和气流与高温热水相接触(方式1);高温饱和气流与低温冷水相接触(方式... 详细信息

为了研究水汽相变中不同构建方式形成的细颗粒长大所需的过饱和环境,利用变物性参数传热传质模型对生长管中过饱和度水平进行了预测,并评价了2种过饱和构建方式:低温饱和气流与高温热水相接触(方式1);高温饱和气流与低温冷水相接触(方式2).同时分析了进气温度、管壁水温度、进气流速和压力对2种构建方式下所得过饱和度的影响.结果表明:变物性与定物性参数下预测过饱和水平有一定的差异性,最大差异性体现在生长管中心线处;方式2获得的过饱和分布较为均匀;气流与水温差较低时,方式1所得平均过饱和度大;温差较高时,方式2所得平均过饱和度大;温差相同时,较低的温度水平更有利于提高生长管中过饱和水平;压力和进气流速的增加有利于生长管过饱和水平均匀化.

关键词：过饱和度传热传质生长管水汽相变

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