检索结果-南通市图书馆

Chinese Science Bulletin 2008年第11期53卷 1665-1670页

作者： DENG PeiHong FEI JunJie ZHANG Jun li junan Department of Chemistry and Material Science Hengyang Normal University Hengyang 421008 China College of Chemistry Xiangtan University Xiangtan 411105 China

A carbon paste electrode modified with multi-walled carbon nanotubes (MWCNT) was prepared and the determination of ultra trace amount of zirconium based on the anodic adsorptive voltammetry of the zirconium-calcium-alizarin red S mix-polynuclear complex is described in this paper for the first time. The results showed that the sensitivity and the selectivity of the method are excellent. The second de-rivative linear scan voltammograms of the complex were recorded by polarographic analyzer from 200 to 1200 mV (vs. SCE) and it was found that the complex can be adsorbed on the surface of the electrode, yielding a peak at about 840 mV, corresponding to the oxidation of ARS in the complex. The peak cur-rent increases linearly with Zr (IV) concentration in the range of 6.0×10-12―6.0×10-11 mol·L-1 (accumu-lation time 120 s), 6.0×10-11―2.0×10-9 mol·L-1 (accumulation time 90 s) and 2.0×10-9―1.0×10-7 mol·L-1 (accumulation time 60 s) and the detection limit (S/N = 3) is 2.0×10-12 mol·L-1 (accumulation time 180 s). The procedure has been successfully applied to the determination of zirconium in the ore samples.

关键词：多壁碳纳米管纳米技术碳电极锆阳极吸附伏安法

Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer

在线全文

学校读者我要写书评

暂无评论

Nano Research 2019年第4期12卷 855-861页

作者： Chengxiang Zhang Xinfu Zhang Weiyu Zhao Chunxi Zeng Wenqing li Bin li Xiao Luo junan li Justin Jiang Binbin Deng David W. McComb Yizhou Dong Division of Pharmaceutics & Pharmaceutical Chemistry College of Pharmacy The Ohio State University Columbus OH 43210 USA Present address: State Key Laboratory of Fine Chemicals Dalian University of Technology Dalian 116024 China College of Pharmacy The Ohio State University Columbus OH 43210 USA Center for Electron Microscopy and Analysis The Ohio State University Columbus OH 43212 USA Department of Materials Science and Engineering The Ohio State University Columbus OH 43210 USA Department of Biomedical Engineering The Ohio State University Columbus OH 43210 USA The Center for Clinical and Translational Science The Ohio State University Columbus OH 43210 USA The Comprehensive Cancer Center The Ohio State University Columbus OH 43210 USA Dorothy M. Davis Heart & Lung Research Institute The Ohio State University Columbus OH 43210 USA Department of Radiation Oncology The Ohio State University Columbus OH 43210 USA

Triple-negative breast cancer(TNBC)is one type of the most aggressive breast can cers with poor prog no *** is of great urgency to develop new therapeutics for treati ng *** on curre nt treatment guideline and genetic informatio n of TNBC,a combi nation al therapy platform in tegrati ng chemotherapy drugs and mRNA encoding tumor suppressor proteins may become an efficacious *** this study,we developed paclitaxel amino lipid(PAL)derived nanoparticles(NPs)to incorporate both chemotherapy drugs and P53 *** PAL P53 mRNA NPs showed superior properties compared to Abraxane? and lipusu? used in the clinic including high paclitaxel loading capacity(24 wt.%,calculated by paclitaxel in PAL),PAL encapsulation efficiency(94.7%±6.8%)and mRNA encapsulation efficiency(88.7%±0.7%).Meanwhile,these NPs displayed synergetic cytotoxicity of paclitaxel and P53 mRNA in cultured TNBC *** importantly,we demonstrated in vivo anti-tumor efficacy of PAL P53 mRNA NPs in an orthotopic TNBC mouse ***,these chemotherapy drugs derived mRNA NPs provide a new platform to integrate chemotherapy and personalized medicine using tumor genetic information,and therefore represent a promising approach for TNBC treatment.

关键词： clitaxel amino lipid derived nano particles mRNA therapeutics combi nation therapy triple- negative breast cancer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

钪-钙-茜素S异多核络合物的极谱吸附波

分析化学 2000年第4期28卷 476-479页

作者：张军黎拒难邓培红 411105 湘潭大学化学系!湘潭

报道了钪-钙-茜素S（ARS）异多核络合物极谱吸附波的形成及利用它测定钪的最佳实验条件。用此方法测定了矿石中的微量钪，并初步探讨了该极谱波的性质和电极反应机理。在单扫描极谱上用等摩尔连续变化法和单纯形法测得络合物组成的摩尔... 详细信息

报道了钪-钙-茜素S（ARS）异多核络合物极谱吸附波的形成及利用它测定钪的最佳实验条件。用此方法测定了矿石中的微量钪，并初步探讨了该极谱波的性质和电极反应机理。在单扫描极谱上用等摩尔连续变化法和单纯形法测得络合物组成的摩尔比为nSe3+:nCa2+:nARS=2:1:2。

关键词：钪茜素S 多核络合物极谱络合吸附波

RESEARCH OF QUANTUM GENETIC ALGORITH AND ITS APPliCATION IN BliND SOURCE SEPARATION

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Electronics(China) 2003年第1期20卷 62-68页

作者： Yang junan li Bin Zhuang Zhenquan (Department of Electronic Science & Technology, USTC, Hefei 230026) Department of Electronic Science & Technology USTC Hefei

This letter proposes two algorithms: a novel Quantum Genetic Algorithm (QGA)based on the improvement of Han's Genetic Quantum Algorithm (GQA) and a new Blind Source Separation (BSS) method based on QGA and Independent Component Analysis (ICA). The simulation result shows that the efficiency of the new BSS method is obviously higher than that of the Conventional Genetic Algorithm (CGA).

关键词： Quantum computation Genetic algorithm Quantum genetic algorithm Independent component analysis, Blind source separation

在线全文

学校读者我要写书评

暂无评论

表面等离子体共振技术研究生物膜的进展

分析化学 2005年第4期33卷 575-579页

作者：于萍崔小强杨帆黎拒难杨秀荣中国科学院长春应用化学研究所电分析化学国家重点实验室中国科学院长春应用化学研究所电分析化学国家重点实验室长春130022 湘潭411105 湘潭大学化学学院长春130022

利用表面等离子体共振技术研究生物膜是近年来兴起的一个热门课题。文章综述了表面等离子体共振技术的基本原理、主要的成膜方式、研究进展以及发展趋势。

关键词：表面等离子体共振技术生物膜传感器综述

A NEW TYPE OF AEROSTATIC THRUST BEARING WITH HIGH STIFFNESS

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

A NEW TYPE OF AEROSTATIC THRUST BEARING WITH HIGH STIFFNESS

钪钇茜素红S异多核络合物极谱吸附波的研究

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： ZHANG junan, YUAN li, FANG Zongde School of Mechatronic Engineering, Northwestern Polytechnical University, Xi’an710072, China

The precision and ultraprecision machinery requires increasing the stiffness of aerostatic bearing. In this paper, a new type of aerostatic thrust bearing with high stiffness is presented. The princip

关键词： Ultraprecision aerostatic bearing pressure groove stiffness.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国稀土学报 1999年第3期17卷 271-274页

作者：黎拒难赵先菊苏生跃湘潭大学化学化工学院湘潭411105

报道了钪钇茜素红Ｓ异多核络合物的形成及该异多核络合物极谱吸附波测定钪的最佳实验条件。用此方法测定了纯氧化钇中的微量钪，并探讨了该极谱波的性质和电极反应机制。在单扫描示波极谱上用单纯形法和改良的平衡移动法测得该异... 详细信息

报道了钪钇茜素红Ｓ异多核络合物的形成及该异多核络合物极谱吸附波测定钪的最佳实验条件。用此方法测定了纯氧化钇中的微量钪，并探讨了该极谱波的性质和电极反应机制。在单扫描示波极谱上用单纯形法和改良的平衡移动法测得该异多核络合物组成的摩尔比为：ｘＳｃ３＋ ∶ｘＹ３＋ ∶ｘＡＲＳ＝１∶２∶５。

关键词：稀土钪钇茜素红S 异多核络合物极谱吸附波

锇联吡啶氧化还原聚合物膜修饰电极对肾上腺素的电催化氧化及安培检测

在线全文

学校读者我要写书评

暂无评论

催化学报 2006年第7期27卷 619-623页

作者：费俊杰谭红艳陈小明黎拒难湘潭大学化学学院

用电化学还原方法制备了一种锇联吡啶氧化还原聚合物（POs—EA）膜修饰电极，并研究了其在磷酸缓冲溶液中的电化学行为和对肾上腺素的电催化氧化作用．结果表明，该修饰电极表现出较为可逆的伏安响应并对。肾上腺素的电化学氧化具有良... 详细信息

用电化学还原方法制备了一种锇联吡啶氧化还原聚合物（POs—EA）膜修饰电极，并研究了其在磷酸缓冲溶液中的电化学行为和对肾上腺素的电催化氧化作用．结果表明，该修饰电极表现出较为可逆的伏安响应并对。肾上腺素的电化学氧化具有良好的电催化性能．与裸金电极相比，POs—EA膜修饰电极大大提高了。肾上腺素的峰电流，降低了。肾上腺素的氧化峰电位．初步探讨了该电极上。肾上腺素的电催化氧化机理．通过检测外加电位为0．29V时的氧化电流对。肾上腺素进行检测，结果表明，其氧化电流和肾上腺素的浓度在5×10^-8～1×10^5mol／L范围内呈良好线性关系，检测限可达1．5×10^-8mol／L．

关键词：锇联吡啶氧化还原聚合物修饰电极肾上腺素电催化安培检测

Studies on the Fermentation Properties of Immobilized Yeast Cells

在线全文

学校读者我要写书评

暂无评论

山地农业生物学报 1993年第2期 94-97页

作者： li junan (Bioengineering Institute of Guiyang. Guiyang, 550002, China) Zhou Jian (Dept. of Hortculture Guizhou Agric. Coll. Guiyang , 550025 ,China)

This paper studied on the fermentation properties of immobilized yeast cells (Saccharomyees cerevisiae)which was embeded in a new carrier, PVA-alginate gel. The results showed a high ethanol productivity was achieved by immobilized yeast cells Ganhua-1 entrapped in this carrier,concentration of immobilized cells reached 10~9/g-gel after immobilized cells were made multiplying culture, time of multiplying cuhure was 36-48h, and the optimum fermentation conditions were:PH range of ferment hquid was between 4 and 6,temperature range was between 30 and 34℃, glucose concentration was the 15%.

关键词： Immobilized cells Saccharomyces cerevisiae Yeast cells Ethanol fermentation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

NO2的示波极谱测定

湘潭大学自然科学学报 1984年第2期 95-102页

作者：黎拒难肖惠黎

本文利用NO2-与芳香族胺类化合物在酸性介质（pH1.3—1.7）中反应生成偶氮化合物。在氨——氯化铵底液（pH9—10）冲,该偶氮化合物在单扫描示波极谱上有一个灵敏的导数波,峰电位约为-0.57V-（对SCE）。NO2-的浓度在4×10-8—2×10-5M与... 详细信息

本文利用NO2-与芳香族胺类化合物在酸性介质（pH1.3—1.7）中反应生成偶氮化合物。在氨——氯化铵底液（pH9—10）冲,该偶氮化合物在单扫描示波极谱上有一个灵敏的导数波,峰电位约为-0.57V-（对SCE）。NO2-的浓度在4×10-8—2×10-5M与波高成线性关系,检测下限达2×10-8M。研究了极谱波的性质,探讨了电极反应机理。并利用该方法测定了井水、河水、池塘水和土壤中的NO2-—N,结果良好。

关键词：示波极谱波高酸度 NO2 电极反应电化学反应峰电位极谱波偶氮化合物