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Personalized federated few-shot node classification

Science China(Information Sciences) 2025年第1期 204-218页

作者： yunfeng ZHAO Xintong HE Guoxian yu jun WANG Yongqing ZHENG Carlotta DOMENICONI School of Software Shandong University Joint SDU-NTU Centre for Artificial Intelligence Research Shandong University Department of Mathematics National University of Singapore Department of Computer Science George Mason University

Personalized federated learning(PFL) aims to train customized models for individual clients in a decentralized setting, with the account of non-independent and identically distributed data across clients. However, most PFL methods adopt uniform classification layers for diverse clients and give rise to error-prone predictions, due to the task heterogeneity notably prominent in decentralized graph data scenarios. Although some PFL solutions setup client-specific classification layers for each client and optimize them only locally, they are corrupted with limited local training data. We propose an innovative solution called federated parameter decoupling and node augmentation(Fed PANo) to address these problems and to achieve personalized federated few-shot node classification, which is a prevalent and challenging but unexplored topic. Specifically, Fed PANo first separates the local model into the GNN and classifier to handle unique client-specific task variations. The GNN is trained through federated learning to capture shared knowledge of graph nodes across clients, while the classifier is custom-designed and trained individually for each client. Additionally, a generic classifier shared among clients is adopted to encourage the GNN's grasp of shared information. Then Fed PANo further proposes the node generator along with its local and collaborative training strategies to deal with the node scarcity of clients. Extensive experimental results on benchmark datasets confirm that Fed PANo outperforms eight competitive baselines across different settings.

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Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches

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Traditional Medicine Research 2025年第2期10卷 37-54页

作者： Yong-Chang Zeng jun-Hong Wu Dan-Dan Xu Kang He Chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-yu Liang Department of Neurology The First Affiliated Hospital of Shenzhen UniversityShenzhen 518020China Pharmaceutical Department The Affiliated TCM Hospital of Guangzhou Medical UniversityGuangzhou 510000China School of Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China Guangzhou Zeli Medical Technology Co. Ltd.Guangzhou 510700China

Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for ***,the bioactive components and underlying mechanisms have not been *** objective of this study was to identify the active components and potential mechanisms of SMW by integrating pharmacological experimentation,serum pharmacochemistry,network pharmacology and molecular ***:HUA rats modelling by high-fat/high-sugar diet and potassium oxonate/adenine oral administration were used to evaluate the pharmacodynamic effects of ***-Q-Exactive-MS/MS was employed to detect the bioactive components present in SMW-containing *** pharmacology and molecular docking were utilized to elucidate the potential targets and underlying ***:SMW effectively ameliorated HUA rats via the inhibition of uric acid(UA)production,promotion of UA excretion,improvement of lipid and glucose metabolic abnormalities,antioxidant,anti-inflammatory and anti-insulin resistance effects.A total of 73 compounds detected in SMW-containing serum were identified as potential active components,with alkaloids,flavonoids,organic acids,and terpenoids emerging as the primary active *** 203 corresponding targets were obtained as SMW anti-HUA/gout targets,which mainly participated in apoptosis,insulin resistance,TNF,PI3K-Akt,HIF-1,NF-κB,MAPK,IL-17 and TLR signaling *** docking indicated that active compounds(***,phellodendrine,quercetin,formononetin,ferulic acid)had superior binding abilities to the key targets(*** carrier family 22 member 12(URAT1),solute carrier family 22 member 6(OAT1),ATP-binding cassette sub-family G member 2(ABCG2),solute carrier family 2,facilitated glucose transporter member 9(GLUT9),xanthine dehydrogenase/oxidase(XDH),transcription factor p65(RELA),toll-like receptor 4(TLR4),prostaglandin G/H synthase 2(PTGS2),caspase-3(CASP3),insulin(INS)).Conclusion:S

关键词： hyperuricemia network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS

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Surface treatments of CdGeAs2 single crystals

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Rare Metals 2019年第7期38卷 683-688页

作者： Wei Huang Bei-jun Zhao Shi-fu Zhu Zhi-yu He Bao-jun Chen Zhen Zhen yun-Xiao Pu College of Materials Science and Engineering Sichuan University

The performances of second harmonic gen eration (SHG) and optical parametric oscillator (OPO) in CdGeAs2 crystal are strongly influenced by surface quality. In this paper, the surfaces of samples were treated by mechanical polishing (MP), chemical polishing (CP), chemical-mechanical polishing (CMP) and CP following CMP closely (CMP + CP). Then, the surface state was characterized by optical microscopy (OM), scanning electron microscopy (SEM), atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). AFM measurements show that an ultra-smooth surface is achieved after CMP + CP treatment and the roughness value is 0.98 nm. Meanwhile, the roughness of the surfaces treated by MP, CP and CMP are 4.53, 2.83 and 1.38 nm, respectively. By XRD rocking curves, the diffraction peak which belongs to the wafer treated by CMP + CP is the highest in intensity and best symmetrical in shape. XPS analysis indicates that Ge4+ proportions of GeO2 in total Ge content of CdGeAs2 wafers' surface after MP, CP, CMP and CMP + CP treatment are 27.6%, 42.8%, 6.1% and 30.3%, respectively.

关键词： CdGeAs2 single crystal Surface treatments Surface roughness

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Ionization of two-electron atom(xenon)studied by Bohmian mechanics theory

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Chinese Physics B 2020年第11期29卷 297-302页

作者： Yang Song Shu Han yu-jun Yang fu-Ming Guo Su-yu Li College of Science Northeast Electric Power UniversityJilin 132012China Archives Northeast Electric Power UniversityJilin 132012China Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China

The ionization dynamics of two-electron atom in an intense laser field is studied by the Bohmian mechanics(BM)theory, and the xenon atomic potential function is used as a model. The single ionization process and double ionization process are calculated by the BM theory and their results are in good agreement with those calculated by numerically solving the time-dependent Schrodinger equation. The analyses of the types, trajectories, and forces of Bohmian particles(BPs)undergoing the single and double ionizations indicate that the re-collision process accounts for a considerable proportion in the singly ionized cases. furthermore, the analysis of the work done by the external force acting on the BPs shows that the quantum force plays an important role in the re-collision process. This work is helpful in understanding the ionization of two-electron atom in an intense laser field.

关键词： Bohmian mechanics quantum force atomic ionization re-collision process

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Resonance-enhanced two-photon ionization of hydrogen atom in intense laser field investigated by Bohmian-mechanics

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Chinese Physics B 2020年第9期29卷 288-294页

Resonance enhanced two-photon ionization process of hydrogen atom via the resonant laser pulse is studied by Bohmian mechanics (BM) method. By analyzing the trajectories and energies of Bohmian particles (BPs), we find that under the action of high frequency and low intensity multi-circle resonant laser pulses, the ionized BPs first absorb one photon completing the excitation, and then absorb another photon, completing the ionization after staying in the first excited state for a period of time. The analysis of work done by the forces shows that the electric field force and quantum force play a major role in the whole ionization process. At the excitation moment and in the excitation-ionization process, the effect of the quantum force is greater than that of the electric field force. Finally, we discuss the principle of work and energy for BPs, and find that the electric field force and quantum force are non-conservative forces whose work is equal to the increment of mechanical energy of the system. In addition, it is proved that the quantum potential energy actually comes from the kinetic energy of the system and the increment of kinetic energy is equal to that of the kinetic energy of the system.

关键词： Bohmian mechanics quantum force resonance-enhanced two-photon ionization

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From Mutation Signature to Molecular Mechanismin the RNA World: A Case of SARS-CoV-2

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Genomics, Proteomics & Bioinformatics 2020年第6期18卷 627-639页

作者： jun yu China National Center for Bioinformation Beijing 100101China CAS Key Laboratory of Genome Sciences and Information Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100190China

As a positive-sense single-strand RNA virus,coronavirus(CoV)possesses some of the largest genomes among RNA viruses,∼30 Kb in size and encodes more than two-dozen proteins that ensure a long-lasting parasitic cellular life leveraging on both informational inheritability and operational integrity by constantly changing the underlying molecular constituents toward harmony with those of the hosts whose genomes harbor over 20,000 genes and 2–3 Gb in ***,taking the advantage of the unprecedented accumulation of genomic sequences,interrogate mutation spectra of SARS-CoV-2 as a whole or of the major clades in details using comprehensive genomic tools and structure chemistry principles.

关键词： details harmony sizes

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Role of decay in the search for double-charm baryons

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Science China(Physics,Mechanics & Astronomy) 2020年第2期63卷 27-28页

作者： fu-Sheng yu School of Nuclear Science and Technology Lanzhou University

Double-charm baryons,whose components are two heavy charm quarks and one light quark,are part of a large family of hadrons predicted by the quark *** on them are helpful to understand the hadron structure and the nature of the strong *** efforts expended over decades of searching,experimental measurements achieved a breakthrough with the first observation of the double-charm baryon of■^++cc(ccu)via■^++cc→Λ^+c K^-π^+π^+ by the LHCb collaboration in 2017[1].Since then,the LHCb collaboration has been leading the experimental studies for doubly charmed baryons[2-6]because they are produced in considerably large numbers in the Large Hadron Collider(LHC).

关键词： interaction. quark double

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Chow’s Theorem for Semi-abelian Varieties and Bounds for Splitting Fields of Algebraic Tori

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Acta Mathematica Sinica,English Series 2019年第9期35卷 1453-1463页

作者： Chia fu yu Institute of Mathematics Academia Sinica & NCTS Astronomy Mathematics Building

A theorem of Chow concerns homomorphisms of two abelian varieties under a primary field extension base change. In this paper, we generalize Chow’s theorem to semi-abelian *** contributes to different proofs of a well-known result that every algebraic torus splits over a finite separable field extension. We also obtain the best bound for the degrees of splitting fields of tori.

关键词： Algebraic tori splitting fields semi-abelian varieties inverse Galois problem

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High Speed Regular Expression Matching Engine with Fast Pre-Processing

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China Communications 2019年第2期16卷 177-188页

作者： Zhe fu jun Li Department of Automation Tsinghua University Research Institute of Information Technology Tsinghua University Tsinghua National Laboratory for Information Science and Technology (TNList)

Regular expression matching is playing an important role in deep inspection. The rapid development of SDN and NFV makes the network more dynamic, bringing serious challenges to traditional deep inspection matching engines. However, state-of-theart matching methods often require a significant amount of pre-processing time and hence are not suitable for this fast updating scenario. In this paper, a novel matching engine called BFA is proposed to achieve high-speed regular expression matching with fast pre-processing. Experiments demonstrate that BFA obtains 5 to 20 times more update abilities compared to existing regular expression matching methods, and scales well on multi-core platforms.

关键词： deep inspection finite automaton regular expression matching pre-processing

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A simple and efficient synthesis of the valsartan

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Chinese Chemical Letters 2008年第7期19卷 759-761页

作者： Chen Xi Zhang Guo jun Zheng fu Qiang Bi yu Lin Li State Key Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou University Lanzhou 730000 China

Valsartan 1, one of the most important agents used in antihypertensive therapy today, was synthesized starting from L-valin methyl ester hydrochloride 2 through four steps in an overall yield of 60%. The key step involves the palladium-catalyzed Suzuki coupling. This method overcomes many of the drawbacks associated with the previously reported syntheses and is more suitable for industrial production.

关键词： Valsartan Antihypertensive L-Valin methyl ester hydrochlofide Synthesis Suzuki coupling

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