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氧化石墨烯和石墨烯的高浓度加工、致密化及应用

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新型炭材料（中英文） 2024年第3期39卷 483-505页

作者：王悦罗家亮鲁哲宏狄俊王苏炜姜炜南京理工大学化学与化工学院国家特种超细粉体工程技术研究中心江苏南京210094 中国科学院合肥物质科学研究院强磁场科学中心安徽合肥230031

由紧密堆叠的石墨烯片组成的致密石墨烯组件具有出色的化学稳定性和优异的力学、热学和电学性能。致密石墨烯组件不存在多孔石墨烯气凝胶中密度低、力学强度低、导电性差和导热性差等问题,是未来便携式电子和智能设备的理想材料。本文... 详细信息

由紧密堆叠的石墨烯片组成的致密石墨烯组件具有出色的化学稳定性和优异的力学、热学和电学性能。致密石墨烯组件不存在多孔石墨烯气凝胶中密度低、力学强度低、导电性差和导热性差等问题,是未来便携式电子和智能设备的理想材料。本文对制备方法进行了总结,包括利用机械分散、蒸发浓缩、离心浓缩和液相剥离法获得的高浓度氧化石墨烯(go)和石墨烯分散液,以及利用真空辅助过滤、界面自组装和压制成型法获得的二维(2D)致密石墨烯基薄膜和三维(3D)致密石墨烯基结构,并评估了各种方法的优缺点。此外,还总结了致密石墨烯基组件在储能、热管理和电磁干扰(EMI)屏蔽方面的应用。最后,概述了致密石墨烯组件在未来研究中面临的挑战和前景。本综述为探索和开发大规模、低成本的制造技术和面向应用的致密石墨烯组件提供参考。

关键词：高浓度分散液致密石墨烯基组件二维薄膜三维结构应用

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Rainbow halos occur less following implantation of extended range of vision one-piece intraocular lenses vs diffractive bifocal intraocular lenses

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 913-919页

作者： Jae-hyung Kim Youngsub Eom seo Yeon Park Soo Youn Choi Ho Sik Hwang jun-Heon Kim Jong Suk Song Hyo Myung Kim seoul Daabom Eye Center Cheongju 28568Republic of Korea Department of Ophthalmology Ansan HospitalKorea University College of Medicine.Seoul 15355Republic of Korea BGN World Tower Eye Clinic Seoul 05551Republic of Korea Department of Ophthalmology Yeouido St.Mary's HospitalCollege of Medicinethe Catholic University of KoreaSeoul 07345Republic of Korea Joeunnun Vision Clinic Seoul 06134Republic of Korea

AIM:To evaluate clinical outcomes following implantation of an extended range of vision intraocular lens(IOL),the ZXR00,and a diffractive multifocal IOL with+2.75 diopters(D)add power,the ***:Totally 30 patients who underwent either bilateral implantation of the ZXR00 IOL with intended emmetropia(ZXR00 emmetropia group:20 eyes)and intended micromonovision(ZXR00 monovision group:20 eyes),or bilateral implantation of the ZKB00 IOL with intended emmetropia(ZKB00 group:20 eyes)were included in this *** acuity at 4 m,80,and 40 cm;and the types of halos(misty,fine,and rainbow)were analyzed at one and three months after ***:There were no significant differences in distance visual acuity among the three *** mean uncorrected intermediate visual acuity was better in the ZXR00 emmetropia and monovision groups(0.02 logMAR and 0.02 logMAR,respectively)than in the ZKB00 group(0.14 logMAR).The mean uncorrected near visual acuity was worse in the ZXR00 emmetropia group(0.26 logMAR)than in the ZXR00 monovision and ZKB00 groups(0.12 logMAR and 0.10 logMAR,respectively).There was an increased incidence of rainbow halos in the ZKB00 group vs in either ZXR00 group(P=0.033).CONCLUSION:Implantation of the ZXR00 IOL with intended micromonovision provide superior visual acuity than implantation of the ZXR00 IOL with intended *** ZXR00 IOLs tend to show a lower incidence of rainbow halos than did the ZKB00 IOL.

关键词： halos intraocular lens diffractive bifocal multifocal rainbow halos

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数字化转型与对外直接投资的非线性关系研究

天津师范大学学报（社会科学版） 2024年第4期 66-77页

作者：薛军周鹏冉南开大学经济学院、跨国公司研究中心天津300071 南开大学经济学院

数字化转型与对外直接投资呈现显著的“倒U型”关系,且全要素生产率在其中发挥重要的中介作用。进一步异质性分析发现,除了初创期和衰退期的企业,处于增长期、成熟期和淘汰期的企业,数字化转型与对外直接投资均存在显著的“倒U型”关系... 详细信息

数字化转型与对外直接投资呈现显著的“倒U型”关系,且全要素生产率在其中发挥重要的中介作用。进一步异质性分析发现,除了初创期和衰退期的企业,处于增长期、成熟期和淘汰期的企业,数字化转型与对外直接投资均存在显著的“倒U型”关系;无论国有企业还是民营企业,“倒U型”关系均显著存在。区域异质性分析发现,在中国东部和中部地区数字化转型与对外直接投资存在显著的“倒U型”关系,而在西部地区不存在。阐述了数字化转型对对外直接投资的双刃剑作用,对于数字经济背景下中国如何促进企业更好“走出去”提供了重要启示。

关键词：数字化转型对外直接投资全要素生产率

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Content Authoring and Cloud System Implementation for Smart Learning

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Journal of Computer and Communications 2015年第5期3卷 137-143页

作者： Hyun-seo Hwang Jin-Tae Park Kyeong-Taek seo jun-Soo Yun Il-Young Moon Oh-Young Kwon Byeong-jun Kim School of Computer Science and Engineering University of Technology and Education Cheon-an Korea ANCLE Inc Cheon-an Korea

In this paper, we implement a content authoring and cloud system for cloud-based smart cloud learning. With the advent of the smartphone and mobile devices such as tablets, the educational paradigm is also changing. Was using the computer to aid in the learning e-learning started in ICT education are evolving Over the variety, in recent years, combines smart learning and social learning, cloud-based smart devices in e-learning the concept of Smart Cloud Smart Education Services Learning was gives rise to the term. Smart Cloud and free running is always the knowledge content uploaded by anyone, anywhere, can also be shared with other users. A terminal and location, without limitations on time, are continuously available to the environment of a high- quality knowledge content was coming through a variety of smart media, open educational content platform is built over the level of the possible conditions than e-learning. In this paper, we develop applications and Web sites that can provide authored content for smart cloud learning. In addition, we have built the cloud for content management and the website that can share content with other users. In the future, should wish to study a way that can provide customized services over the learner analysis based on big data technology.

关键词： Smart Cloud Learning Smart Learning E-Learning Big Data Mobile Device

肝细胞癌中UBE2S互作蛋白的筛选及预后模型构建

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吉林大学学报（医学版） 2024年第1期50卷 168-177页

作者：王小燕张豪郭泽皓曹骏莫之婧桂林医学院智能医学与生物技术学院实验教学中心广西桂林541199 桂林医学院广西高校生物化学与分子生物学重点实验室广西桂林541199 桂林医学院智能医学与生物技术学院生物化学教研室广西桂林541199

目的:筛选泛素结合酶E2S (UBE2S)互作蛋白并构建肝细胞癌(HCC)基于UBE2S互作蛋白的预后模型(UIPM),分析UIPM评估HCC患者预后的价值。方法:采用免疫共沉淀(Co-IP)技术筛选与Flag-UBE2S结合的蛋白复合体,经十二烷基硫酸钠-聚丙烯酰胺凝胶... 详细信息

目的:筛选泛素结合酶E2S (UBE2S)互作蛋白并构建肝细胞癌(HCC)基于UBE2S互作蛋白的预后模型(UIPM),分析UIPM评估HCC患者预后的价值。方法:采用免疫共沉淀(Co-IP)技术筛选与Flag-UBE2S结合的蛋白复合体,经十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDSPAGE)和Western blotting法验证后,采用液相色谱-质谱联用仪(LC-MS)分析鉴定UBE2S互作蛋白,并对互作蛋白进行基因本体论(go)功能和京都基因与基因组百科全书(KEGG)信号通路富集分析。采用R软件survival包筛选癌症基因组图谱(TGGA)中HCC预后相关蛋白与UBE2S互作蛋白取交集,通过LASSO回归分析从交集蛋白中获取关键蛋白构建UIPM,并建立预后模型风险评分公式,按照风险评分的中位值将TGGA中HCC患者分为高风险组和低风险组,通过受试者工作特征曲线(ROC)评估UIPM的预测准确性,并采用国际癌症基因组联盟(ICGC)数据库对UIPM预测准确性进行再次验证。采用单因素和多因素Cox回归分析评估UIPM风险评分是否为HCC的预后独立危险因素,并进一步构建列线图模型。结果:Co-IP联合LC-MS分析得到97个UBE2S互作蛋白。go功能和KEGG信号通路富集分析,互作蛋白主要与半胱氨酸型内肽酶活性、氧化应激和细胞死亡有密切关联。TCGA筛选出5 163个HCC预后相关蛋白,与UBE2S互作蛋白取交集,获得40个预后相关互作蛋白,LASSO回归分析得到7个关键蛋白,包括UBE2S、热休克蛋白家族A成员8(HSPA8)、异质性胞核核糖核蛋白H1(HNRNPH1)、含TCP1伴侣蛋白亚基3 (CCT3)、真核翻译起始因子2亚基1 (EIF2S1)、活化蛋白C激酶1受体(RACK1)和肌动蛋白相关蛋白2/3复合体亚基4(ARPC4),并构建了UIPM,高和低风险组HCC患者生存率存比较差异有统计学意义(P<0.05)。ROC曲线,UIPM预测HCC患者1、2和3年UIPM风险评分的ROC曲线下面积(AUC)值均大于0.7,表明预测模型准确度较高。ICGC数据库数据也证实UIPM预测准确度较高。单因素和多因素Cox回归分析,UIPM风险评分是HCC患者的独立预后危险因素(P<0.05)。列线图预测HCC患者生存率与实际生存率之间有较好的一致性。结论:97个互作蛋白与UBE2S相互作用,可能通过氧化应激和铁死亡相关通路的失调促进HCC发生发展。UIPM风险评分是HCC预后的独立危险因素,可以用于预测HCC患者预后。而UBE2S、HSPA8、HNRNPH1、CCT3、EIF2S1、RACK1和ARPC4有望成为HCC新的生物标志物和治疗靶点。

关键词：泛素结合酶E2S 肝细胞癌免疫共沉淀液相色谱-质谱联用仪预后分析

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SYSTEM ENTITY STRUCTURES FOR SUITES OF SIMULATION MODELS

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第3期4卷 1-11页

作者： BERNARD P.ZEIGLER CHUNGMAN seo DOOHWAN KIM RTSync Corp.530 Bartow Drive Suite A Sierra Vista AZ85635USA

We describe how to develop a suite of models in the MS4 Modeling Environment(MS4 Me).The approach employs the operation of merging of System Entity Structures supported by the *** construction,the suite of models can be hosted on Model Store,the cloud-based repository of models provided by MS4 systems as a basis for further collaborative model development.A suite of models,relating to Health Care is used as an *** this paper,we review basic concepts of the SES needed to support of suites of simulation *** then consider the concept of multiple aspects that provides more advanced capabilities to construct and manipulate suites of *** this background,we go on to discuss a methodology for developing suites of simulation models and cloud-based technology for storing and sharing such models in a marketplace of ***,we discuss future research and developments needed to bring the marketplace into common use by modeling and simulation practitioners.

关键词： System entity structure suite of models component-based modeling systems of systems.

Increased thalamocortical connectivity from the affected thalamus to the unaffected hemisphere in a stroke patient

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Neural Regeneration Research 2020年第8期15卷 1568-1568页

作者： Sung Ho Jang You Sung seo Sung jun Lee Department of Physical Medicine and Rehabilitation College of MedicineYeungnam University

Consciousness is controlled by complicated actions of various neural structures(Schiff,2010;Long et al.,2016).The thalamocortical connections between the central thalamus and cerebral cortex are considered an important neural structure for consciousness(Laureys et al.,2000;Schiff,2010;Jang and Lee,2015).Here,we report a patient who revealed increased thalamocortical connectivity from the affected thalamus to the unaffected hemisphere through interthalamic adhesion.

关键词： al. patient thalamus

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A pilot proof-of-concept study of a modified device for one-step endoscopic ultrasound-guided biliary drainage in a new experimental biliary dilatation animal model

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World Journal of Gastroenterology 2014年第19期20卷 5859-5866页

作者： Tae Hoon Lee jun Hyuck Choi Sang Soo Lee Hyun Deuk Cho Dong Wan seo Sang-Heum Park Sung Koo Lee Myung-Hwan Kim Do Hyun Park Division of Gastroenterology Department of Internal MedicineSoonchunhyang University School of MedicineCheonan HospitalChungcheongnamdo 330-721South Korea Division of Gastroenterology Department of Internal MedicineUniversity of Ulsan College of MedicineSeoul 138-736South Korea Department of Pathology Soonchunhyang University School of MedicineCheonan HospitalChungcheongnam-do 330-721South Korea

AIM: To evaluate the technical feasibility of a modified tapered metal tip and low profile introducer for one-step endoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) in a new experimental biliary dilatation ... 详细信息

关键词： Endoscopic ultrasound Biliary drainage Biliary dilation Feasibility Complications

Simplified fistula dilation technique and modified stent deployment maneuver for EUS-guided hepaticogastrostomy

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World Journal of Gastroenterology 2014年第17期20卷 5051-5059页

作者： Woo Hyun Paik Do Hyun Park jun-Ho Choi Joon Hyuk Choi Sang Soo Lee Dong Wan seo Sung Koo Lee Myung-Hwan Kim jung Bok Lee Division of Gastroenterology Department of Internal MedicineUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 138-736South Korea Department of Internal Medicine Inje University Ilsan Paik HospitalKoyang 411-706South Korea Department of Clinical Epidemiology and Biostatics University of Ulsan College of MedicineAsan Medical CenterSeoul 138-736South Korea

AIM: To evaluate the success rates, procedural time and adverse event rates of the modified methods in endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS).

关键词： Endoscopic ultrasonography Biliary drainage Hepaticogastrostomy Treatment outcome Adverse event