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Light(Science & Applications) 2024年第2期13卷 333-346页

作者： Yifan sun Qian Li Ling-jun Kong Xiangdong Zhang Key Laboratory of advanced optoelectronic quantum architecture and measurements of Ministry of Education Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic SystemsSchool of PhysicsBeijing Institute of Technology100081BeijingChina

Compared with electrical neural networks,optical neural networks(ONNs)have the potentials to break the limit of the bandwidth and reduce the consumption of energy,and therefore draw much attention in recent *** far,several types of ONNs have been ***,the current ONNs cannot realize the acceleration as powerful as that indicated by the models like quantum neural *** to construct and realize an ONN with the quantum speedup is a huge ***,we propose theoretically and demonstrate experimentally a new type of optical convolutional neural network by introducing the optical *** is called the correlated optical convolutional neural network(COCNN).We show that the COCNN can exhibit“quantum speedup”in the training *** character is verified from the two *** is the direct illustration of the faster convergence by comparing the loss function curves of the COCNN with that of the traditional convolutional neural network(CNN).Such a result is compatible with the training performance of the recently proposed quantum convolutional neural network(QCNN).The other is the demonstration of the COCNN’s capability to perform the QCNN phase recognition circuit,validating the connection between the COCNN and the ***,we take the COCNN analog to the 3-qubit QCNN phase recognition circuit as an example and perform an experiment to show the soundness and the feasibility of *** results perfectly match the theoretical *** proposal opens up a new avenue for realizing the ONNs with the quantum speedup,which will benefit the information processing in the era of big data.

关键词： process quantum convolution

Tuning heterogeneous microstructures to enhance mechanical properties of nano-TiN particle reinforced Haynes 230 composites by laser powder bed fusion

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Rare Metals 2024年第9期43卷 4548-4565页

作者： Wen-jie Liu Hui Li Qian-Xing Yin He-jun Du School of Power and Mechanical Engineering Wuhan UniversityWuhan 430072China The Institute of Technological Sciences Wuhan UniversityWuhan 430072China School of Mechanical&Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

Laser powder bed fusion(LPBF)is considered to be one of the most promising additive manufacturing technologies for producing components with geometries and high geometrical precision that are unattainable by traditional *** superalloy exhibits exceptional mechanical and high-temperature performances,rendering it a prime candidate for advanced aero-engine *** the high demand for LPBF-manufactured superalloys,the superalloy is one of the materials manufactured difficultly by LPBF due to their large laser absorptivity fluctuation,poor molten pool stability and sharp temperature ***,superalloys are characterized by severe pores,undesirable coarse columnar grains and poor mechanical *** this work,the effect of nano-TiN particles on defects,molten pool characteristics and microstructure and performance of the composites were *** 4.5 wt%TiN/Haynes230 samples exhibited exceptional nanohardness and elastic modulus with maximum values reaching 5.53 GPa and 240.03 GPa,*** superior mechanical properties were attributed to the combined effects of spatter and gas pore inhibition,grain refinement and duplex nanophases ***,the stability of molten pool was enhanced,and spatter was effectively suppressed by adding nano-TiN particles,while grain refinement and columnar to equiaxed transitions were ***,the matrix exhibited a high dislocation density due to a significant hindrance of dislocation movement caused by massive nano-phases(e.g.,TiN and M_(23)C_(6)),resulting in the formation of extensive dislocation tangles and *** work offers novel insights into the role of nanoparticles reinforced superalloy composites by LPBF.

关键词： Composites Laser powder bed fusion Molten pool characteristics Microstructure Mechanical properties

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In Vivo Voltammetric Imaging of Metal Nanoparticle-Catalyzed Single-Cell Electron Transfer by Fermi Level-Responsive Graphene

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Research 2024年第1期2023卷 271-280页

作者： Qing Xia Rui Liu Xueqin Chen Zixuan Chen jun-jie Zhu State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023P.R.China Shenzhen Research Institute of Nanjing University Shenzhen 518000P.R.China

Metal nanomaterials can facilitate microbial extracellular electron transfer(EET)in the electrochemically active ***,the role of nanomaterials/bacteria interaction in this process is still ***,we reported the single-cell voltammetric imaging of Shewanella oneidensis MR-1 at the single-cell level to elucidate the metal-enhanced EET mechanism in vivo by the Fermi level-responsive graphene *** oxidation currents of~20 fA were observed from single native cells and gold nanoparticle(AuNP)-coated cells in linear sweep voltammetry *** the contrary,the oxidation potential was reduced by up to 100 mV after AuNP *** revealed the mechanism of AuNP-catalyzed direct EET decreasing the oxidation barrier between the outer membrane cytochromes and the *** method offered a promising strategy to understand the nanomaterials/bacteria interaction and guide the rational construction of EET-related microbial fuel cells.

关键词： Fermi voltammetry Electron

Al-doped ZnO/WO_(3) heterostructure films prepared by magnetron sputtering for isopropanol sensors

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Rare Metals 2024年第1期43卷 247-256页

作者： Wei-Xiang Gao Xue-Ting Chang Xiao-jie Zhu jun-Feng Li Ying-Chang Jiang Dong-Sheng Wang Chuan-Xiao Yang Shi-Bin sun College of Logistics Engineering Shanghai Maritime UniversityShanghai 201306China College of Ocean Science and Engineering Shanghai Maritime UniversityShanghai 201306China Institute of Logistics Science and Engineering Shanghai Maritime UniversityShanghai 201306China

Metal oxide semiconductors(MOSs) are ideal sensing materials for detecting volatile organic compounds due to their low cost, diversity, high stability, and ease of production. However, it remains a grand challenge to develop the MOSs-based gas sensors for sensing isopropanol with desired performance via a simple, effective,and controllable method. Herein, we reported the preparation of the Al-doped Zn O(AZO)/WO_(3) heterostructure films by directly depositing the AZO coating onto the WO_(3) coating using a strategy of magnetron sputtering. The AZO/WO_(3) heterostructure films were constructed by numbers of irregular nanoparticles that were interconnected with each other. The AZO/WO_(3) heterostructure films-based gas sensors exhibited excellent isopropanolsensing performance with high response, promising selectivity, low detection limit, fast response rate, wide detection range, and ideal reproducibility. The promising isopropanol-sensing performance of the AZO/WO_(3) heterostructure films arises mainly from their high uniformity, unique microstructures with high surface roughness,and the construction of the heterostructure between the AZO and WO_(3) coatings. This work provides a versatile approach to prepare the MOSs-based heterostructure films for assembling the gas sensors.

关键词： Metal oxide semiconductors Gas sensors Aldoped ZnO/WO_(3) Heterostructure films Isopropanol Magnetron sputtering

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A Wideband High-Gain Sawtooth Slot Array Antenna with Frequency-Scanning at Lower Frequency and Fixed-Beam at Higher Frequency

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Chinese Journal of Electronics 2024年第2期33卷 463-471页

作者： Qiang sun Yongling BAN jun HU School of Electronic Science and Engineering University of Electronic Science and Technology of China

Exploring the multifunctional array antenna suitable for complex communication environment has very important research value. In this paper, a millimeter wave(mm-wave) double longitudinal sawtooth slot array antenna(DLSA) based on substrate integrated waveguide(SIW) technology is proposed, which has wideband, highgain and novel beam characteristics. Two irregular longitudinal slots are etched on the SIW conductor surface as the radiation structure. To improve the bandwidth of the DLSA, the metallized vias are added at the transition point of the slots to construct multiple resonant frequency points. By adjusting the size of the slots and the position of the metallized vias, the phase constant can be regulated, and the unusual beam characteristics can be obtained. That is to say, in the lower frequency band, the beam pointing angle increases with frequency. In the higher frequency band,the beam pointing angle is maintained at a fixed angle. Finally, to improve the antenna gain, a 16 × 8 DLSA is fabricated, measured and discussed. The proposed antenna has an impedance matching bandwidth close to 9.7 *** 27 to 33 GHz, the beam pointing angle changes from 8° to 29°. From 33 to 37 GHz, the beam pointing angle is fixed at 29°, and the pointing angle error range is ±1°. In addition, the measured maximum gain is 22.9 d Bi at32 GHz.

关键词： Antenna measurements Slot antennas Surface waves Resonant frequency Gain measurement Conductors Frequency measurement

Unlocking T cell exhaustion:Insights and implications for CAR-T cell therapy

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3416-3431页

作者： Dian Xiong Haijun Yu Zhi-jun sun State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyFrontier Science Center for Immunology and MetabolismTaikang Center for Life and Medical ScienceWuhan UniversityWuhan 430079China Department of Radiation and Medical Oncology Hubei Province Cancer Clinical Study CenterHubei Key Laboratory of Tumor Biological BehaviorsZhongnan Hospital of Wuhan UniversityWuhan 430071China

Chimeric antigen receptor T(CAR-T)cell therapy as a form of adoptive cell therapy(ACT)has shown significant promise in cancer treatment,demonstrated by the FDA-approved CAR-T cell therapies targeting CD19 or B cell maturation antigen(BCMA)for hematological malignancies,albeit with moderate outcomes in solid ***,despite these advancements,the efficacy of CAR-T therapy is often compromised by T cell exhaustion,a phenomenon that impedes the persistence and effector function of CAR-T cells,leading to a relapse rate of up to 75%in patients treated with CD19 or CD22 CAR-T cells for hematological *** to overcome CAR-T exhaustion employ state-of-the-art genomic engineering tools and single-cell sequencing *** this review,we provide a comprehensive understanding of the latest mechanistic insights into T cell exhaustion and their implications for the current efforts to optimize CAR-T cell *** insights,combined with lessons learned from benchmarking CAR-T based products in recent clinical trials,aim to address the challenges posed by T cell exhaustion,potentially setting the stage for the development of tailored next-generation approaches to cancer treatment.

关键词： Cancer immunotherapy CAR-T therapy T cell exhaustion Tumor immune microenvironment Spatial immune contexture Single-cell technologies CAR-T engineering Combination therapy

Survey on performance of vertical slot and nature-like fishways at Angu hydropower station, Southwest China

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Water Science and Engineering 2024年第1期17卷 83-91页

作者： jun-jian sun Jia-yue Shi Qi Zhang Xiao-tao Shi jun-jun Tan PowerChina Huadong Engineering Corporation Limited Hangzhou 311122China Hubei International Science and Technology Cooperation Base of Fish Passage China Three Gorges UniversityYichang 443002China

To restore dam-blocked natural fish migratory passages,a growing number of artificial fishways have been built in water conservancy and hydropower projects in *** Angu hydropower station involved diverse important fish habitats in the lower reaches of the Daduhe River in Southwest ***,a vertical slot fishway(VSF)and a nature-like fishway(NLF)were built near the backwater area of the reservoir to connect the upstream and downstream *** and aquatic ecological surveys were conducted after the completion of the project to estimate the fish passing effect of the two *** results indicated that both fishways were in effective operation and could maintain the desired hydrodynamic conditions and be used by several local fish *** the survey,149 fish from 15 species and 111 fish from 17 species were captured by the traps in the VSF and NLF,respectively,while 1263 fish from 27 species were found in the downstream *** species captured in the VSF were not found in the NLF,and vice versa,which implied the different preferences of ***,3789 signals including 2099 upward ones and 1690 downward ones were monitored with an ultrasonic fish detector at the inlet of the *** findings revealed the characteristics of fish species observed in and near the fishways and provided valuable insights into the different fish passing capabilities of VSFandNLF.

关键词： Vertical slot fishway Nature-like fishway Aguatic ecological survey Fishwaymonitoring Statistical analysis

Engineering phonon thermal transport in few-layer PdSe_(2)

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Frontiers of physics 2024年第3期19卷 135-141页

作者： Meilin Li Huanhuan sun jun Zhou Yunshan Zhao Phonon Engineering Research Center of Jiangsu Province Center for Quantum Transport and Thermal Energy ScienceInstitute of Physics Frontiers and Interdisciplinary SciencesSchool of Physics and TechnologyNanjing Normal UniversityNanjing 210023China

Engineering phonon transport in low-dimensional materials has great significance not only for fundamental research,but also for thermal management applications of electric ***,due to the difficulties of micro and nano processing and characterization techniques,the work on tuning phonon transport at nanoscale are *** this work,by introducing Ar+plasma,we probed the phonon transport in two-dimensional(2D)layered semiconductor PdSe_(2)under different defect *** using thermal bridge method,the thermal conductivity was measured to decrease by 50%after a certain Ar+irradiation,which implied a possible phase ***,Raman characterizations were performed to show that the Raman sensitive peaks of PdSe_(2)was red-shifted and finally became disappeared with the increase of defect concentration.“Defect engineering”proves be a practical strategy in tuning the phonon thermal transport in low-dimensional materials,thus providing guidance for potential application in designing thermoelectric devices with various emerging materials.

关键词： phonon transport PdSe_(2) defects thermal bridge method

A Deep Model for Partial Multi-label Image Classification with Curriculum-based Disambiguation

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Machine Intelligence Research 2024年第4期21卷 801-814页

作者： Feng sun Ming-Kun Xie Sheng-jun Huang MIIT Key Laboratory of Pattern Analysis and Machine Intelligence College of Computer Science and TechnologyNanjing University of AeronauticsandAstronauticsNanjing211106China

In this paper,we study the partial multi-label(PML)image classification problem,where each image is annotated with a candidate label set consisting of multiple relevant labels and other noisy *** PML methods typically design a disambiguation strategy to filter out noisy labels by utilizing prior knowledge with extra assumptions,which unfortunately is unavailable in many real ***,because the objective function for disambiguation is usually elaborately designed on the whole training set,it can hardly be optimized in a deep model with stochastic gradient descent(SGD)on *** this paper,for the first time,we propose a deep model for PML to enhance the representation and discrimination *** the one hand,we propose a novel curriculum-based disambiguation strategy to progressively identify ground-truth labels by incorporating the varied difficulties of different *** the other hand,consistency regularization is introduced for model training to balance fitting identified easy labels and exploiting potential relevant *** experimental results on the commonly used benchmark datasets show that the proposed method significantlyoutperforms the SOTA methods.

关键词： Partial multi-label image classification curriculum-based disambiguation consistency regularization label difficulty candidatelabel set.