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Rare Metals 2024年第3期43卷 1017-1029页

作者： Xiang Han Min Xu Lan-Hui Gu Chao-Fei Lan Min-Feng Chen jun-jie lu Bi-Fu Sheng Peng Wang Song-Yan Chen Ji-Zhang Chen College of Materials Science and Engineering Co-Innovation Center of Efficient Processing and Utilization of Forestry ResourcesNanjing Forestry UniversityNanjing210037China Department of Physics Xiamen UniversityXiamen361005China Western Digital Corporation MilpitasCA95035USA

Silicon has ultrahigh capacity,dendrite-free alloy lithiation mechanism and low cost and has been regarded as a promising anode candidate for solid-state *** to the low infiltration of solid-state electrolyte(SSE),not the unstable solid-electrolyte interphase(SEI),but the huge stress during lithiation-and delithiation-induced particle fracture and conductivity lost tend to be the main *** this study,starting with micron-Si,a novel monothetic carbon conductive framework and a MgO coating layer are designed,which serve as electron pathway across the whole electrode and stress releasing layer,*** addition,the in situ reaction between Si and SSE helps to form a LiF-rich and mechanically stable SEI *** a result,the mechanical stability and charge transfer kinetics of the uniquely designed Si anode are significantly ***,high initial Coulombic efficiency,high capacity and durable cycling stability can be achieved by applying the Si@MgO@C anode in *** example,high specific capacity of 3224.6 mAh·g^(-1)and long cycling durability of 200 cycles are *** work provides a new concept for designing alloy-type anode that combines surface coating on particle and electrode structure design.

关键词： Lithium-ion battery(LIB) Solid-state electrolyte(SSE) Silicon anode Stress relief Coating

Reinforcing the continent mechanism of continent cutaneous diversions by wrapped rectus abdominis muscle flap： a preliminary experimental study

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Chinese Medical Journal 2009年第9期122卷 1087-1091页

作者： ZHANG Xin-ru XU Yue-min FENG Chao YU Jian-jun SONG lu-jie FEI Xiao-fang Department of Urology Shanghai Jiaotong University AffiliatedShanghai 6th Hospital Shanghai 200023 China

Background Continent cutaneous diversion （CCD） has been widely used in almost any lower urinary reconstruction. We have been continually trying to modify this procedure because of the high complications rate, especially as they relate to the efferent tube. In this study, we reported a modified procedure with a tapered ileum wrapped by the rectus abdominalis flap （RAMF） and assessed the feasibility of this new technique to achieve urinary continence. Methods A procedure in which two ileal segments were tapered and connected to a U-shaped reservoir was performed in ten dogs. A RAMF with its blood supply was wrapped around one of the tapered ileum. In control groups, the tapered ileum was brought to the abdominal skin. Urodynamic studies were conducted In the 1st, 3rd and 6th months post-operatively. The data of maximum inner pressure （MIP） and functional pressure length （FPL） in every group at each phase were recorded. Retrograde radiograms of the efferent limbs were performed before sacrifice. Results MIP in the study group was significantly higher than that in the control group at each phase （P 〈0.05）. However no significant differences in MIP or FPL were found in the study group between an empty and full reservoir. In the control group, MIP increased （P 〈0.05） and FPL decreased significantly （P 〈0.05） compared with an empty and full reservoir. Retrograde radiograms confirmed that efferent limbs were positioned straigh beneath the abdominal wall. Histological examination of the study group demonstrated a layer of striated muscle around the outside surface of the ileum. Conclusion The continent mechanism of tapered ileum can be enhanced by extra support from wrapped RAMF.

关键词： urinary diversions continent urinary reservoir abdomen rectus muscles

Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng jie Shen Jinxing lu Chuqiang Huang Zhuoyuan Chen Feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Anodes

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang Zhao Mingkai Zhang Qimeng Li Xuemin Wang jie lu Ying Han Yanning Cai Department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： jie Jin Huajing Zhang Qianying lu Linqiang Tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia lu Sijia Tian Yanmei Zhao Wenjie Ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina Clinical Medical Center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health Central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina School of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review focuses on the use of nanocarrier systems for the efficient and precise delive ry of siRNAs,discussing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can precisely"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic strategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

Catalyst–Support Interaction in Polyaniline‑Supported Ni_(3)Fe Oxide to Boost Oxygen Evolution Activities for Rechargeable Zn‑Air Batteries

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Nano-Micro Letters 2025年第1期17卷 176-190页

作者： Xiaohong Zou Qian lu Mingcong Tang jie Wu Kouer Zhang Wenzhi Li Yunxia Hu Xiaomin Xu Xiao Zhang Zongping Shao Liang An Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and TechnologyNanjing University of Information Science and TechnologyNanjing 210044People’s Republic of China Department of Chemistry The Chinese University of Hong KongMa Lin BuildingShatinHong Kong SAR 999077People’s Republic of China WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia Research Institute for Advanced Manufacturing The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China

Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3)Fe oxide/PANI)with a robust hetero-interface,which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm^(-2)and specific activity of 2.08 mA cm_(ECSA)^(-2)at overpotential of 300 mV,3.84-fold that of Ni_(3)Fe *** is revealed that the catalyst–support interaction between Ni_(3)Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond,thus promoting the charge and mass transfer on Ni_(3)Fe *** the excellent activity and stability,rechargeable Zn-air batteries with optimum Ni_(3)Fe oxide/PANI are assembled,delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm^(-2).The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts.

关键词： Catalyst-support interaction Supported catalysts Heterointerface Oxygen evolution reaction Zn-air batteries

Studies on the genetic differentiation of fifteen chicken breeds by mtDNA COI gene

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第十二次全国畜禽遗传标记研讨会

作者： GAO Yu-shi,TANG Xiu-jun,TU Yun-jie,lu jun-xian,SHI Zu-hao,ZHANG Xiao-yan (Poultry Institute,Chinese Academy of Agricultural Sciences,Yangzhou 225003,China)

Introduction MtDNA was used widely as molecular genetic marker because of its especial structural character, and CO I gene was used far-ranging in the studies of taxonomy,Species identification,genetic diversity of population and molecular evolutionary in vertebrata and *** this study,the part sequence of CO I gene was used as molecular marker to identify thirteen indigenous chicken breeds and two import breeds,in order to analysis genetic polymorphism and the connection of molecular biology geography evolvement of interpopulation and intrapopulation about fifteen chicken breeds.

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电磁带隙结构滤波特性

天津大学学报（自然科学与工程技术版） 2004年第9期37卷 818-822页

作者：丁荣林胡俊杰王雷卢山天津大学电子信息工程学院天津300072

电磁带隙(EBG)结构是一种周期性结构,存在明显的禁带效应.为了解其特性,研究了二维平面电磁带隙结构,该装置采用在接地金属板上光刻出阵列小孔的方法制作.在对EBG结构进行仿真和计算时,利用了完全匹配层(PML)吸收边界条件的时域有限差分... 详细信息

电磁带隙(EBG)结构是一种周期性结构,存在明显的禁带效应.为了解其特性,研究了二维平面电磁带隙结构,该装置采用在接地金属板上光刻出阵列小孔的方法制作.在对EBG结构进行仿真和计算时,利用了完全匹配层(PML)吸收边界条件的时域有限差分法(FDTD).设计的程序采用C++和Matlab语言混合编制,既简化了程序又保持了C语言速度快的特点.最后通过大量实验和研究,提出了一种新型EBG结构,在此基础上设计出宽阻带并具有双频段带隙特性的滤波电路.

关键词：电磁带隙时域有限差分法完全匹配层

Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils

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芍药脱水素基因PlDHN2的克隆及表达分析

第六届全国自由基生物学与自由基医学学术会议和海峡两岸自由基生物学与自由基医学学术会议

作者： De-Liang Zhang. Yue-Ting Zhang, jun-jie Yin, Bao-lu Zhao Center for Brain and Cognitive Sciences, Institute of Biophysics, Academia Sinica, Beijing, China,

Stroke is the third leading cause of death as dementia is a main symptom of Alzheimer’s disease. One of the important mechanisms in the pathogeny of stroke is free radicals production during the reperfusion period, therefore the effects of a kind of natural antioxidant, i.e. Crataegus flavonoids (CF) on brain ischemic insults were investigated in Mongolian gerbil stroke model. Results showed that pretreatment of the animals with CF decreased reactive oxygen species (ROS) production, thiobarbituric acid reactive substances content, and nitrite/nitrate concentration in brain homogenate, increased the brain homogenate-associated antioxidant level in a dose dependent manner. CF pretreatment increased the amount of biological available NO by scavenging of superoxide anion produced during reperfusion. At same time, in the process of ischemia/reperfusion brain damage, the content of nitrite/nitrate, the end product of NO, increased, NO detected by ESR decreased, while oral pretreatment with CF decreased the nitrite/nitrate content in the brain homogenate and increased the biological available NO concentration in a dose dependent manner. The increasing effect of antioxidant on NO might be due to its scavenging effect on superoxide anion, which could react with NO into peroxynitrite. iNOS was implied in delayed neuron death after brain ischemic damage and it was found that pretreatment with CF could decrease the protein level of TNF-αand NFκB, and increase the mRNA level of NOS estimated by Western blotting and RT-PCR. More neurons survived and less cells suffered apoptosis in the hippocampal CA1 region of CF treated animal brain. These results suggest that oral administration of this antioxidant increases the antioxidant level in the brain and protects the brain against delayed cell death caused by ischemia/reperfusion injury.

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植物生理学报 2017年第7期53卷 1297-1305页

作者：陈煜马燕国静李俊杰韩璐璐郭先锋山东农业大学林学院山东泰安271018

脱水素(DHN)在植物经受逆境胁迫条件下对于保护细胞内蛋白质和膜结构具有重要作用。本研究以芍药‘大富贵’芽为试材,采用RT-PCR技术克隆得到1个脱水素基因PlDHN2(Gen Bank登录号KY272747),该基因具有399 bp的开放阅读框,编码132个氨基... 详细信息

脱水素(DHN)在植物经受逆境胁迫条件下对于保护细胞内蛋白质和膜结构具有重要作用。本研究以芍药‘大富贵’芽为试材,采用RT-PCR技术克隆得到1个脱水素基因PlDHN2(Gen Bank登录号KY272747),该基因具有399 bp的开放阅读框,编码132个氨基酸,具有DHN家族特有的Y、S和K片段,属于典型的Y_3SK_2型脱水素;基因结构分析表明,PlDHN2具有1个长度为84 bp的内含子,位于S片段。以拟南芥和大麦的脱水素蛋白分类为参照,聚类分析结果表明,PlDHN2与Y_nSK_2型脱水素聚合在一起,进化关系较近。半定量PCR分析显示,PlDHN2在芍药各器官中均有表达,其中在芽中的表达最高。亚细胞定位观察结果显示:PlDHN2蛋白定位于细胞质膜和细胞核中。表达特性分析表明,PlDHN2在低温、高温、水淹和ABA胁迫条件下,表达量均不同程度地上调,说明该基因可能参与了芍药对低温等非生物胁迫的耐受调节过程。

关键词：芍药脱水素克隆亚细胞定位表达分析