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A Note on Casoratian Solutions to Two-Dimensional Toda Lattice

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Communications in Theoretical Physics 2007年第3期47卷 390-392页

作者： ZHANG Da-jun wu hua Department of Mathematics Shanghai University Shanghai 200444 China

In this short paper we generalize the conditions that Casoratian entries satisfy for the two-dlmenslonal Toda lattice. Although we finally conclude that our generalization is trivial in some sense for getting new solu... 详细信息

关键词： Casoratian solution two-dimensional Toda lattice bilinear

A long noncoding RNA involved in rice reproductive development by negatively regulating osa-miR160

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Science Bulletin 2017年第7期62卷 470-475页

作者： Meng Wang hua-jun wu jun Fang Chengcai Chu Xiu-Jie Wang State Key Laboratory of Plant Genomics Institute of Genetics and Developmental BiologyChinese Academy of Sciences Northeast Institute of Geography and Agroecology Key Laboratory of Soybean Molecular Design BreedingChinese Academy of Sciences

Long noncoding RNAs （IncRNAs） participate in the regulation of multiple biological processes via diverse manners, one of which is functioning as endogenous target mimics （eTMs） to modulate microRNAs （miRNAs） by competing for their targets. Previously, we have predicted one IncRNA （osa-eTM160） as an endogenous repressor of osa-miR160 and validated the target mimicry ability of osa-eTM160 for ath-miR160 in Arabidopsis thaliana, yet the functions of osa-eTM160 in rice remain obscure. Here, we demonstrated that osa-eTM160 attenuated the repression of osa-miR160 on osa-ARF18 mRNAs during early anther developmental stages through the target mimicry manner, therefore to regulate rice seed setting and seed size. These findings revealed the roles of osa-eTM160 in rice, and indicated that lncRNAs with eTM functions may serve as temporal regulators to modulate the effects of miRNAs at specific developmental stages.

关键词： microRNA IncRNA miR160 Target mimic

Anti-proliferative and pro-apoptotic effects of tectorigenin on hepatic stellate cells

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World Journal of Gastroenterology 2010年第31期16卷 3911-3918页

作者： jun-hua wu Yu-Rong Wang wu-Yang huang Ren-Xiang Tan Institute of Functional Biomolecules State Key Laboratory of Pharma ceutic al Biote chnologyNanjing UniversityNanjing 210093Jiangsu ProvinceChina

AIM: To investigate the effect of tectorigenin on proliferation and apoptosis of hepatic stellate cells (HSC)-T6 cells. METHODS: HSC-T6 cells were incubated with tectorigenin at different concentrations, and their proliferation was assessed by bromodeoxyuridine incorporation assay. Apoptosis was detected by flow cytometry assay with Hoechst 33342 staining. Also, generation of reactive oxygen species (ROS), intracellular [Ca2+]i, potential of mitochondrial membrane, activities of cytochrome c and caspase-9 and-3 were investigated to explore a conceivable apoptotic pathway. RESULTS: Tectorigenin suppressed the proliferation of HSC-T6 cells and induced apoptosis of HSC-T6 cells in a time-and dose-dependent manner. Tectorigenin at the concentration of 100 μg/mL greatly inhibited the viability of HSC-T6 cells and induced the condensation of chromatin and fragmentation of nuclei. When treated for 48 h, the percentage of cell growth and apoptosis reached 46.3% ± 2.37% (P = 0.004) and 50.67% ± 3.24% (P = 0.003), respectively. Furthermore, tectorigenin-induced apoptosis of HSC-T6 cells was associated with the generation of ROS, increased intracellular [Ca2+]i, loss of mitochondrial membrane potential, translocation of cytochrome c, and activation of caspase-9 and -3. CONCLUSION: Tectorigenin inhibits proliferation of HSC-T6 cells and induces apoptosis of HSC-T6 cells.

关键词： Tectorigenin Apoptosis Hepatic stellate cells Hepatic fibrosis Mitochondria Proliferation

Pro-apoptotic effects of tectorigenin on human hepatocellular carcinoma HepG2 cells

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World Journal of Gastroenterology 2012年第15期18卷 1753-1764页

作者： Chun-Ping Jiang Hui Ding Da-hua Shi Yu-Rong Wang Er-Guang Li jun-hua wu The First Clinical Medical College NanjingUniversity of Chinese Medicine Nanjing 210046 Jiangsu Province China Department of Hepatobiliary Surgery The Affiliated Drum Tower Hospital Medical School Nanjing University Nanjing 210008 Jiangsu Province China Jiangsu Key Laboratory of Molecular Medicine State Key Laboratory of Pharmaceutical Biotechnology Medical School Nanjing University Nanjing 210093 Jiangsu Province China

AIM:To investigate the effects of tectorigenin on human hepatocellular carcinoma(HCC)HepG2 ***:Tectorigenin,one of the main components of rhizome of Iris tectorum,was prepared by simple methods,such as extraction,filtration,concentration,precipitation and ***2 cells were incubated with tectorigenin at different concentrations,and their viability was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** was detected by morphological observation of nuclear change,agarose gel electrophoresis of DNA ladder,and flow cytometry with Hoechst 33342,Annexin V-EGFP and propidium iodide *** of reactive oxygen species was quantified using *** Ca2+was monitored by Fura *** membrane potential was monitored using Rhodamine *** of cytochrome c from mitochondria to cytosol was detected by Western *** of caspase-3,-8 and-9 were investigated by Caspase Activity Assay ***:The viability of HepG2 cells treated by tectorigenin decreased in a concentration-and timedependent *** concentration that reduced the number of viable HepG2 cells by 50%(IC50)after 12,24 and 48 h of incubation was 35.72 mg/L,21.19 mg/L and 11.06 mg/L,***,treatment with tectorigenin at 20 mg/L resulted in a very slight cytotoxicity to L02 cells after incubation for 12,24 or 48 *** at a concentration of 20 mg/L greatly inhibited the viability of HepG2 cells and induced the condensation of chromatin and fragmentation of *** induced apoptosis of HepG2 cells in a time-and dose-dependent *** with the viability rate,induction of apoptosis was the main mechanism of the anti-proliferation effect of tectorigenin in HepG2 ***,tectorigenininduced apoptosis of HepG2 cells was associated with the generation of reactive oxygen species,increased intracellular[Ca2+]i,loss of mitochondrial membrane potential,transloca

关键词： Tectorigenin Iris tectorum maxim Apop-tosis Hepatocellular carcinoma HepG2 Mitochondria Liver cancer

Synthesis of Cucurbit [ n ] uril-based Rotaxanes

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有机化学 2003年第Z1期23卷 261-262页

作者： LIU Si-Min wu Xiao-jun YAO jun-hua wu Cheng-Tai Department of Chemistry Wuhan University Wuhan 430072 Department of Chemistry Wuhan University Wuhan 430072 Instrumentation Analysis and Research Center Sun Yat-Sen University Guangzhou 510275 Department of Chemistry Wuhan University Wuhan 430072

　　Non-covalent attractive forces are commonly employed in biological systems to drive the assembly of highly orga nized supramolecular entities from relatively simple subunits.……

关键词： biological systems

Preparation and Anti-Oxidation Properties of Ti(CN) Films Deposited by P CVD

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材料热处理学报 2004年第05B期25卷 851-853页

作者： PANYing-jun CHENShu-hua wuXin-jie LIPing-sheng ZHANGXi-ju DepartmentofMaterialandMetallurgy WuhanUniversityofScienceandTechnologyWuhanChina

Using metallo-organatic compound TPT as the source of Ti, H13 mould steels were coated with Ti(CN) films by plasma-assisted chemical vapor deposition (PCVD) and the properties of Ti(CN) films were studied. Under the appropriate temperature and pressure, Ti(CN) films on H13 mould steel surfaces had the highest micro-hardness of HV1760 at 500°C, and the films showed excellent anti-oxidation property below 500°C. The lifetime of Ti(CN)-coated augers and dies could be enhanced 7 and 4 times longer than those of untreated respectively.

关键词： PCVD 钛薄膜反氧化显微硬度

A New Statistic for Variable Selection in Questionnaire Analysis

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Journal of Systems Science and Systems Engineering 2001年第3期13卷 315-322页

作者： ZHANG jun-hua, FANG Wei-wu Institute of Applied Mathematics, Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing 100080, China Institute of Applied Mathematics Academy of Mathematics and System Sciences Chinese Academy of Sciences Beijing 100080 China

In this paper, a new statistic is proposed for variable selection which is one of the important problems in analysis of questionnaire data. Contrasting to other methods, the approach introduced here can be used not on... 详细信息

关键词： questionnaire variable selection information divergence statistic

Synethesis and Crystal Structure of Bi(ethylenediamine)copper Tetracyanonickelate(II)

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Chinese Journal of Structural Chemistry 2000年第3期19卷 187-190页

作者： LUO jun hua ②\ wu Mao Xiang\ WANG Yan Ming\ GAO Dong Shou Li Ding\ CHENG Chang Zhang (Fujian Insitute of Research on the Structure of Matter, the Chinese Academy of Sciences, Fuzhou, 350002) 中科院福建物质结构所福建福州 350 0 0 2

The crystal structure of the title compound C 8H 16 CuN 8Ni has been determined by single crystal X ray diffraction. The crystal is triclinic with space group P1, a=6.494(3), b=7.270(4), c=7.936(5) , α=106.67(3), β=91.33(4), γ=106.80(6)°, V=341.3(3)  3, Z=1, M r=346.54, F(000)=177, μ =2\^933mm -1 , D c =1.686 Mg/m 3. The final R factor is 0.0603 for 1214 unique observed reflections 〔 I≥2σ(I) 〕. The structure consists of 〔Cu(en) 2〕 2+ (en=ethylenediamine) cations and 〔Ni(CN) 4〕 2- anions linked together by two of the CN groups (the remaining two act as unidentate ligands) to form infinite chains, in the chain, the hydrogen bonds of N(4)…H-N(5) exist,with distance 3.148 , at the same time the hydrogen bonds of N(4)…H-N(7a) and N(5)-H…N(1a) (a: x-1,y-1,z-1 ) between the interchains also exist, with distances of 3.160 and 3.124 , so it forms a three\|dimensional structure of the title compound.

关键词： cyanide bridged complexes copper(II) complex crystal structure.

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我国名师研究的现状及前瞻

教育理论与实践 2017年第10期37卷 46-50页

作者：成俊华吴丽山西师范大学教师教育学院山西临汾041004 山西省教育科学研究院山西太原030009

以中国知网(CNKI)名师研究核心期刊及硕博论文数据为基础,对我国名师研究现状进行分析表明,当前我国关于名师的研究主要集中在名师成长、教学、培养、案例、评选、特征、内涵、作用及效应等九个方面。未来名师研究将向理论研究系统化、... 详细信息

以中国知网(CNKI)名师研究核心期刊及硕博论文数据为基础,对我国名师研究现状进行分析表明,当前我国关于名师的研究主要集中在名师成长、教学、培养、案例、评选、特征、内涵、作用及效应等九个方面。未来名师研究将向理论研究系统化、实践研究深入化、研究方法多样化、研究视角多元化方向发展。

关键词：名师研究成长教学培养评选特征