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SYNTHESIS AND HERBICIDAL ACTIVITY OF A- [2-（ FLUORO-SUBSTITUTED PHEMOXY）-PROPIONYLOXY] ALKYLPHOSPHONATES

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SYNTHESIS AND HERBICIDAL ACTIVITY OF A- [2-（ FLUORO-SUBSTIT...

第17届国际磷化学大会

作者： Yan-jun li hong-Wu He* Key Laboratory of Pesticide & ChemicaBiology of Ministry of Education Central China Normal UniversitWuhan 430079 People’s Republic of China

＜正＞The title compound was synthesized by the reaction of O,O-dimethyl 1-hydroxyalkyl phosphonate with 2-（fluoro-substituted phenoxy）propionyl chloride according to a literature

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离子交换树脂D001对罗丹明B的吸附特性

化工环保 2017年第5期37卷 543-547页

作者：刘保锋洪军王丽童晨中国地质大学环境学院纳米矿物材料及应用教育部工程研究中心湖北武汉430074

采用强酸性阳离子交换树脂D001作为吸附剂吸附脱除水溶液中的罗丹明B(Rh B)。SEM和FTIR表征结果显示:D001树脂表面存在孔隙,可增加树脂的比表面积;树脂表面的磺酸基团可通过与阳离子染料Rh B络合而将其吸附。实验结果表明:Langmuir等温... 详细信息

采用强酸性阳离子交换树脂D001作为吸附剂吸附脱除水溶液中的罗丹明B(Rh B)。SEM和FTIR表征结果显示:D001树脂表面存在孔隙,可增加树脂的比表面积;树脂表面的磺酸基团可通过与阳离子染料Rh B络合而将其吸附。实验结果表明:Langmuir等温吸附模型能更好地描述树脂对Rh B的吸附规律,升高温度有利于树脂吸附Rh B;吸附过程符合Lagergren准一级动力学方程,初始Rh B质量浓度为20 mg/L时吸附活化能为7.06 k J/mol;树脂对Rh B的吸附是一个自发的、吸热的、熵推动的过程;颗粒扩散为吸附过程的控制步骤;树脂具有良好的重复使用性能。

关键词：阳离子交换树脂罗丹明B 吸附热力学吸附动力学

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降低永磁同步电动机噪声的方法

电机与控制学报 2018年第7期22卷 19-26页

作者：于慎波钟双双赵海宁翟凤军李红郭凯沈阳工业大学机械工程学院辽宁沈阳110870

从永磁同步电动机声压级频谱分析着手,分析主要峰值频率的来源。首先,通过实验获取了在4k Hz开关频率下、满载工况时永磁同步电动机的声压级频谱图,找出对应的主要峰值频率。其次,从三个方面分析了产生声压级峰值的原因。产生主要声压... 详细信息

从永磁同步电动机声压级频谱分析着手,分析主要峰值频率的来源。首先,通过实验获取了在4k Hz开关频率下、满载工况时永磁同步电动机的声压级频谱图,找出对应的主要峰值频率。其次,从三个方面分析了产生声压级峰值的原因。产生主要声压级峰值的频率包括旋转频率、极对数频率、每相齿槽频率、齿槽频率、径向电磁力频率、开关频率等力源频率。通过实验模态分析测得了定子系统的固有模态频率和振型。计算了考虑轴向模态的相对声强系数。最后,提出了降低噪声的综合解决方案,使某型号永磁同步电动机满载时额定转速下噪声值降低了5d B(A)。为低噪声永磁同步电动机的设计提供了参考。

关键词：噪声永磁同步电动机力源固有模态相对声强系数

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen li Hui Ye Xue-Zhi Zhang Jian-Xiang liu hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between june 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

From blocker to booster:Harnessing garnet surface chemistry for advanced solid-state electrolytes

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Nano Research 2025年第1期18卷 323-331页

作者： jun Cheng Xuan Zhou hongqiang Zhang Zhen Zeng Yuanyuan li Yulong Zhu Yingsheng liao lijie Ci Deping li State Key Laboratory of Precision Welding and Joining of Materials and Structures School of Materials Science and EngineeringHarbin Institute of Technology(Shenzhen)Shenzhen 518055China

Garnet electrolytes with high ionic conductivity and electrochemical stability are widely used as fillers to fabricate composite solid electrolytes(CPEs)within polymer ***,the performance of CPEs is significantly influenced by the surface characteristics of the garnet ***,the impact of garnet surface characteristics on CPEs was systematically investigated and a conversion from a typically unstable and Lewis basic surface to a more stable Lewis acidic surface was realized,which is shown to be more conductive to the improved performance of *** simultaneously removing the li_(2)CO_(3)layer and applying a li-Al-O coating,the influence of surface characteristics on CPEs was *** Lewis acid li-Al-O surface coating not only promotes lithium salt dissociation,improving the ionic conductivity and ionic transfer number,but also prevents the reformation of the passive Lewis basic li_(2)CO_(3)*** to garnet with a Lewis basic li_(2)CO_(3)surface,the garnet modified with a Lewis acid li-Al-O coating enhances CPEs,which exhibit an improved critical current density of 1.0 mA·cm^(-2)and highly stable lithium symmetric cell cycling for 400 h at 0.2 mA·cm^(-2).This research highlights the importance of surface chemistry in the design of high-performance solid-state batteries and presents a strategic modification approach for garnetbased CPEs.

关键词： garnet electrolyte composite solid electrolyte surface chemistry all-solid-state batteries

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乙型肝炎病毒感染与小儿IgA肾病的关系

复旦学报（医学版） 2004年第2期31卷 146-148,154,F005页

作者：周利军徐虹方利君马学玲张月娥张秀荣复旦大学附属儿科医院肾内科上海医学院病理学系上海200032

目的　探讨HBV感染与IgA肾病的关系。方法　回顾性分析 1992 .10 - 2 0 0 0 .2期间 35例确诊IgAN患儿的临床表现和亚型分类。以半定量评分判断肾小管损害、肾间质炎症及纤维化程度 ;以EliSA法检测血清HBV感染标志 ;以PAP免疫酶法进行... 详细信息

目的　探讨HBV感染与IgA肾病的关系。方法　回顾性分析 1992 .10 - 2 0 0 0 .2期间 35例确诊IgAN患儿的临床表现和亚型分类。以半定量评分判断肾小管损害、肾间质炎症及纤维化程度 ;以EliSA法检测血清HBV感染标志 ;以PAP免疫酶法进行肾组织HBsAg、HBcAg检测 ;以原位分子杂交及HBVDNA HBsAg、HBcAg双标记染色检测肾组织HBVDNA。结果　血清HBV感染阳性 11例 (31.4 % ) ,远高于普通人群的携带率。肾组织HBV抗原阳性共 12例 (30 .6 % )。HBsAg在肾小球的阳性率高于肾小管 ,而HBcAg则在肾小管高于肾小球。各种亚型IgA肾病均可有HBsAg的沉积 ;肾小管的HBcAg阳性率高于肾小球。肾组织中HBVDNA阳性者为 4例 (6 6 .0 % ) ,均为肾小管上皮HBVDNA阳性。小儿IgAN肾组织HBcAg阳性患者其肾小管病变、间质炎症及纤维化程度较阴性者严重且差异显著 (P <0 .0 0 1)。结论　小儿HBV感染与IgA肾病密切相关 ;

关键词：乙型肝炎病毒感染小儿 IgA肾病回顾性分析肾间质损害拉米呋定

Influence of REV and ALV-J Co-infection on Immunologic Function of T Lymphocytes and Histopathological in Broiler Chickens

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Influence of REV and ALV-J Co-infection on Immunologic Funct...

Application of traditional Chinese medicine preparations among outpatients with coronary heart disease and its association with the guidelines-recommended medications

全国动物生理生化第十一次学术交流会

作者： GUO Hun-jun,li hong-mei,CHENG Zi-qiang,liU Jian-zhu,CUI Zhi-zhong~* (College of Veternary Medicine,Shandong Agricultural University,Tai''an City,China)

＜正＞[Objective]To study the effect of single- and co-infection with REV and ALV-J on T lymphocytes bioactivities and histopathology in broiler chickens.[Method]Blood and spleen T lymphocytes bioactivities including lymphoproliferation responses and cytotoxicitic responses and pathological histopathology of spleen were detected in broiler chickens singl- or co-infected with REV and ALV-J at different days post inoculation,the viruses’ expression in infected broiler’s spleen were detected with immunofluorescence assay（IFA）.[Result]The results indicate that,blood and spleen T lymphocytes proliferate responses and cytotoxicity in broilers infected with REV or/and ALV-J were inhibited in the whole observed period compared with controls,in the co-infected chickens they were inhibited more severely than in the *** histopathology of spleen in infected chickens at 17 and 37 days post inoculation indicated that cell interium increased,the numbers of lymphocytes decreased and the regrowth were destroyed or decreased,especially more significiant at 17dpi than at 37 *** different numbers of virus were detected in spleen lymphocytes in REV-infected and/or ALV-J-infected chickens,*** co-infected chickens’ spleen,both REV and ALV-J were detected and the total numbers of viruses were more than in chickens single-infected with REV or ALV-J.[Conclusion]It can be concluded that co-effect of REV and ALV-J can cause more immunosuppression on T lymphocytes bioactivities in broiler chickens than single-effect of ALV-J or REV,which contribute to the sever histopathology and the product of tumor *** will be helpful for understanding of the effect of co- or dulpti-infection with many viruses and control them in poultry.

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Application of traditional Chinese medicine preparations amo...

胃癌淋巴结转移灶与原发灶P-糖蛋白的表达及意义

第十三次全国心血管病学术会议

作者： GUO Xiang-yu,liU jun,li hong-juan li,QIN Lan-ping,ZHAO Dong Capital Medical University Beijing Anzhen Hospital Beijing Institute of Heart,Lung and Blood Vessel Diseases.Beijing 100029, China

Objective To determine the application of traditional Chinese medicine preparations(TCMP) in the secondary prevention of coronary heart disease(CHD) and its association with the use of guidelines-recommended western *** A cross-sectional survey was conducted among 2803 CHD outpatients,a representative sample of *** general demographic data,disease histories,and information on drugs(including TCMP and western drugs) previously and currently

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世界华人消化杂志 2008年第21期16卷 2404-2407页

作者：李勇莉李红军张敏高建凯高福莲新乡医学院组织胚胎学教研室河南省新乡市453003 新乡医学院第一附属医院内科河南省卫辉市453100

目的:探讨P-糖蛋白(P-glycoprotein,P-gp)在胃癌淋巴结转移灶与原发灶表达水平的差异及其与胃癌临床病理特征的关系.方法:应用免疫组化的方法检测19例伴有淋巴结转移的胃癌患者的淋巴结转移灶、胃癌原发灶和正常胃黏膜的P-gp表达.结果:... 详细信息

目的:探讨P-糖蛋白(P-glycoprotein,P-gp)在胃癌淋巴结转移灶与原发灶表达水平的差异及其与胃癌临床病理特征的关系.方法:应用免疫组化的方法检测19例伴有淋巴结转移的胃癌患者的淋巴结转移灶、胃癌原发灶和正常胃黏膜的P-gp表达.结果:淋巴结转移灶P-gp表达的阳性率高于原发灶(84.20% vs 52.63%,P<0.05);淋巴结转移灶P-gp表达与患者性别、年龄、肿瘤分化程度和浸润深度无关;胃癌原发灶P-gp的表达与胃癌组织分化程度和浸润深度有关(P<0.05),与性别和年龄无关.P-gp表达阳性率在高、中分化者较低分化者高,肿瘤浸润未达浆膜者高于已穿越浆膜者.结论:胃癌淋巴结转移灶的P-gp表达高于原发灶,淋巴结转移灶与原发灶P-gp表达和胃癌临床病理特征的关系不同.

关键词：胃癌淋巴结转移多药耐药 P-糖蛋白