检索结果-南通市图书馆

Recanalization of anastomotic occlusion following rectal cancer surgery using a rendezvous endoscopic technique with transillumination:A case report

引用

World Journal of Gastroenterology 2024年第37期30卷 4149-4155页

作者： jun Chi Guang-Yu Luo Hong-Bo Shan jun-zhong lin Xiao-jun Wu Jian-jun Li Department of Endoscopy Sun Yat-Sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina State Key Laboratory of Oncology in South China Guangzhou 510060Guangdong ProvinceChina Guangdong Provincial Clinical Research Center for Cancer Guangzhou 510060Guangdong ProvinceChina Department of Colorectal Surgery Sun Yat-Sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Colorectal anastomotic occlusion is a serious complication of colorectal cancer *** several treatment strategies have been proposed,the mana-gement of anastomotic occlusion remains *** this report,we present a case of anastomotic occlusion recanalization performed using a novel technique involving two endoscopes,one for radial incision and the other serving as a guide *** novel technique offers significant advantages in terms of operational feasibility,reduced invasiveness,rapid recovery,and shortened hospital *** SUMMARY A 37-year-old man underwent low anterior resection and prophylactic double-lumen ileostomy for rectal cancer in june,*** months later,complete anastomotic occlusion was observed on ***,we developed a novel atresia recanalization *** endoscopes were placed,one through the colonic anastomosis and the other through the anus.A radial incision was successfully made from the colonic side,guided by the light of the endoscope from the anal *** recanal-ization was performed within 20 *** weeks after recanalization,colonoscopy revealed that the diameter of the colorectal anastomosis was approximately 16 mm and the patient therefore underwent stoma reversal in *** the follow-up period of approximately one year,the patient remained well and no stenosis or obstruction symptoms were *** Endoscopic atresia recanalization of colorectal anastomotic occlusion assisted by an opposing light source is safe and effective.

关键词： Endoscopy Atresia recanalization Anastomotic occlusion Light source Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oxaliplatin-containing adjuvant chemotherapy improves the survival of locally advanced rectal cancer patients with pathological complete response after pre-operative chemoradiotherapy

引用

Gastroenterology Report 2018年第3期6卷 195-201,I0002页

作者： Jian-Hong Peng jun-zhong lin Yu-Ming Rong Ying Zhu Yu-Xiang Deng Yu-Jie Zhao Zhen-Hai Lu Xiao-jun Wu Zhi-zhong Pan Department of Colorectal Surgery Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer Medicine651 Dongfeng Road EastGuangzhouGuangdong 510060P.R.China VIP Region Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer Medicine651 Dongfeng Road EastGuangzhouGuangdong 510060P.R.China

Background:The necessity for adjuvant chemotherapy(ACT)in locally advanced rectal cancer(LARC)patients who achieve pathological complete response(pCR)after pre-operative chemoradiotherapy(CRT)is still not *** aimed to investigate the therapeutic value of ACT in these ***:Clinical data were retrospectively collected from 105 consecutive LARC patients who achieved pCR after pre-operative CRT and underwent radical tumor resection between December 2008 and April 2014 in a comprehensive cancer *** chemotherapy(CT)was administered by combining oxaliplatin with capecitabine(XELOX regimen).Disease-free survival(DFS)and overall survival(OS)rates of patients with or without ACT were ***:Eighty-three(79.0%)patients received ACT and 22(21.0%)did *** a median follow-up of 49 months,the ACT group had a significantly higher 3-year DFS rate(92.8 vs 86.4%,p=0.029)and 3-year OS rate(95.1 vs 86.1%,p=0.026)than the non-ACT *** multivariable analyses,the presence of ACT was an independent prognostic factor for DFS(hazard ratio[HR]:0.271;95%confidence interval(CI):0.080–0.916;p=0.036)but not for *** benefit was more obvious in patients younger than 60 years via subgroup analysis(adjusted HR:0.106;95%CI:0.019–0.606;p=0.012).Conclusions:Oxaliplatin-containing ACT may confer survival benefits to patients with pCR,particularly younger ***,the routine use of ACT in patients with pCR needs further validation.

关键词： Adjuvant chemotherapy rectal cancer pre-operative chemoradiotherapy pathological complete response survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Upper Bounds on the Multicolor Ramsey Numbers r_(k)(C_(4))

引用

Acta Mathematicae Applicatae Sinica 2025年第1期41卷 286-294页

作者： Tian-yu LI Qi-zhong lin Center for Discrete Mathematics Fuzhou UniversityFuzhou 350108China

The multicolor Ramsey number r_(k)(C_(4))is the smallest integer N such that any k-edge coloring of KN contains a monochromatic C_(4).The current best upper bound of r_(k)(C_(4))was obtained by Chung(1974)and independently by Irving(1974),i.e.,r_(k)(C_(4))≤k^(2)+k+1 for all k≥*** is no progress on the upper bound since *** this paper,we improve the upper bound of r_(k)(C_(4))by showing that r_(k)(C_(4))≤k^(2)+k-1 for even k≥*** improvement is based on the upper bound of the Turan number ex(n,C4),in which we mainly use the double counting method and many novel ideas from Firke,Kosek,Nash,and Williford[***,Ser.B 103(2013),327-336].

关键词： Multicolor Ramsey number Turan number 4-cycle

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Germline mutational profile of Chinese patients under 70 years old with colorectal cancer

引用

Cancer Communications 2020年第11期40卷 620-632页

作者： Teng-Jia Jiang Fang Wang Ying-Nan Wang Jia-Jia Hu Pei-Rong Ding jun-zhong lin Zhi-zhong Pan Gong Chen Jian-Yong Shao Rui-hua Xu Qi Zhao Feng Wang State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineDepartment of OncologySun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Molecular Diagnosis Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Experimental Research Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Colorectal Surgery Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China

Background:Inherited susceptibility accounts for nearly one-third of colorectal cancer(CRC)predispositions and has an 80%-100%lifetime risk of this ***,there are few data about germline mutations of hereditary CRC-related genes in Chinese patients with *** study aimed to assess the prevalence of gene mutations related to cancer susceptibility among Chinese patients with CRC,differences between Chinese and Western patients,and the phenotypegenotype ***:We retrospectively collected tumor samples from 526 patients with CRC under 70 years old who underwent hereditary CRC genetic testing.A series of bioinformatic analyses,as well as statistical comparisons,were ***:We found that 77 patients(14.6%)harbored functional variants of the 12 *** mutation frequencies of the top 5 mutated genes were 6.5%for MutL homolog 1(MLH1),5.1%for MutS homolog 2(MSH2),1.0%for MSH6,0.8%for PMS1 homolog 2(PMS2),and 0.8%for APC regulator of the WNT signaling pathway(APC).Our data showed much higher rates of mutations of MSH6 and PMS2 genes among all mismatch repair(MMR)genes as compared with those in Western *** in MLH1,MSH2,and MSH6 were found to be mutually *** with MLH1 or MSH2 mutations had higher frequencies of personal history of cancer(MLH1:20.6%vs.8.7%;MSH2:25.9%vs.8.6%)and family history of cancer than those without these mutations(MLH1:73.5%vs.48.4%;MSH2:70.4%vs.48.9%),and the lesions were more prone to occur on the right side of the colon than on the left side(MLH1:73.5%vs.29.3%;MSH2:56.0%vs.31.0%).The proportion of stage I/II disease was higher in patients with MLH1 mutations than in those without MLH1 mutations(70.6%vs.50.7%),and the rate of polyps was higher in patients withAPC mutations than in those with wild-type APC(75.0%vs.17.4%).Conclusion:These results provide a full-scale landscape of hereditary susceptibility over 12 related genes in CRC patients and suggest that a comprehensive multi-ge

关键词： colorectal cancer genetic testing germline mutation hereditary CRC syndromes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thickness and sp3 bond modulation of（Ti/tetrahedral amorphous carbon）_n multilayer coatings

引用

Tungsten 2025年第1期7卷 152-160页

作者： Zhi-jun Xie Jia-lin Li ling Gong Xiang-Li zhong Hong-Jia Song Jin-Bin Wang National-Provincial Laboratory of Special Function Thin Film Materials School of Materials Science and Engineering Xiangtan University

The durability of wear-resistant tetrahedral amorphous carbon（ta-C） coatings is intimately linked to their thickness and the concentration of *** enhance the lifespan of the coatings,we have prepared a multilayer coating consisting of alternating layers of Ti and ta-C,denoted as（Ti/ta-C）_n,using arc ion plating.A multi-layer structure in conjunction with stage cooling is employed to enhance the thickness and promote *** results indicate that the ID/IGvalue,representing the ratio of the intensity of the D peak to that of the G peak in Raman spectroscopy,decreases from 0.85 when no stage cooling is applied to 0.35 when stage cooling is employed,suggesting an enhancement in the fraction of sp3bonds within the *** obtained（Ti/ta-C）_n multilayer coating without peeling off has a maximum thickness of 1.14 μm,which is almost double that of the ta-C coating single layer *** the same time,the coating has a low coefficient of friction,down to 0.069,and maintains excellent friction properties with a wear rate of 3.4×10-6mm3·N-1·*** results conclusively show that the preparation technology can enhance both thickness and sp3bonding in ta-C coatings,significantly expanding their utility across tools,molds,and precision engineering components.

关键词： Arc ion plating Multilayer structure sp3 bond Ta-C coating Wear resistance

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Metamorphopsia after surgery for rhegmatogenous retinal detachment

引用

International Journal of Ophthalmology(English edition) 2025年第1期18卷 168-177页

作者： Han-Tao Zhou zhong lin National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

Improvements in surgical techniques have led to 90% success in the surgical repair of rhegmatogenous retinal detachment(RRD).However,anatomical reattachment of the retina does not ensure complete recovery of visual *** incidence of metamorphopsia remains the most common postoperative complaint,from 24% to 88.6%.Currently,the risk factors of metamorphopsia are categorized into macular involvement,retinal shift,outer retinal folds,subretinal fluid,secondary epiretinal membrane,outer retinal layer damage,and surgical *** associations of metamorphopsia with postoperative best-corrected visual acuity and postoperative vision-related quality of life were still *** most popular methods for assessment of metamorphopsia remain the Amsler grid and *** treatments cannot progress beyond the management of negative visual sensations,through methods such as occlusion therapy and aniseikonia-correcting *** main treatment approach involves RRD prevention and the management of risk factors that can lead to postoperative metamorphopsia after RRD *** research concerning metamorphopsia treatment,further upgrades of auxiliary inspection methods,and more accurate microstructural assessments are needed to address this common complication.

关键词： retinal detachment rhegmatogenous retinal detachment metamorphopsia visual distortion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The association between weight stability and parenteral nutrition characteristics and survival in patients with colorectal cancer

引用

Gastroenterology Report 2019年第6期7卷 419-425,I0002页

作者： Wenli Liu Aiham Qdaisat Eric Lee Jason Yeung Khanh Vu jun-zhong lin Todd Canada Shouhao Zhou Lorenzo Cohen Eduardo Bruera Sai-Ching J.Yeung Department of Palliative Rehabilitation and Integrative MedicineThe University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Emergency Medicine The University of Texas MD Anderson Cancer CenterHoustonTXUSA McGovern Medical School HoustonTXUSA Biomedical Science Texas A&M UniversityCollege StationTXUSA Department of General Internal Medicine The University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Colorectal Surgery Sun Yat-sen University Cancer CenterGuangzhouGuangdongP.R.China Division of Pharmacy The University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Public Health Sciences Pennsylvania State University School of MedicineHersheyPAUSA Department of Endocrine Neoplasia and Hormonal Disorders The University of Texas MD Anderson Cancer CenterHoustonTXUSA

Objective:Knowledge about the impact of metabolic disturbances and parenteral nutrition(PN)characteristics on the survival of cancer patients receiving PN is *** aimed to assess the association between clinical and PN characteristics and survival in colorectal-cancer patients receiving PN ***:Our study included 572 consecutive colorectal-cancer patients who had received PN support between 2008 and *** characteristics,body mass index,weight,medical/surgical history,indication for PN,PN data and survival were *** between clinical and PN characteristics and survival were analysed with important confounding ***:The final cohort included 437 evaluable patients,with a mean age of 57 ***-one percent of the study population had advanced stage of colorectal *** weight(weight change≥2.5%)prior to PN initiation[hazard ratio(HR)=1.41,P=0.023]was adversely associated with survival after adjusting for multiple factors including cancer *** obstruction(HR=1.75,P=0.017)as a PN indication was associated with worse survival when compared with without bowel *** PN amino acid by ideal body weight(g•kg^(-1))(HR=0.59,P=0.029)was associated with longer survival,whereas a higher percentage of non-PN intravenous calories(HR=1.04,P=0.011)was associated with shorter survival independently of confounding ***:Body mass index and weight stability can be useful nutritional indices for survival prediction in cancer patients receiving *** planning should take into account of non-PN calories to achieve optimal energy support and *** research is needed to define optimal PN amino-acid requirement and energy balance.

关键词： BMI weight loss non-parenteral calorie energy balance parenteral nutrition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis

引用

Signal Transduction and Targeted Therapy 2022年第3期7卷 918-933页

作者： Jin-Fei lin Pei-Shan Hu Yi-Yu Wang Yue-Tao Tan Kai Yu Kun Liao Qi-Nian Wu Ting Li Qi Meng jun-zhong lin Ze-Xian Liu Heng-Ying Pu Huai-Qiang Ju Rui-Hua Xu Miao-Zhen Qiu Department of Medical Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University510060 GuangzhouP.R.China Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer Chinese Academy of Medical Sciences510060 GuangzhouP.R.China Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease The Sixth Affiliated Hospital(Guangdong Gastrointestinal and Anal Hospital)Sun Yat-sen University510655 GuangzhouP.R.China Department of Pathology Sun Yat-sen University Cancer Center510060 GuangzhouP.R.China Department of Gastroenterology and Urology Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University410013 ChangshaP.R.China Department of Colorectal Surgery Sun Yat-sen University Cancer Center510060 GuangzhouP.R.China

Metabolic enzymes have an indispensable role in metabolic reprogramming,and their aberrant expression or activity has been associated with ***,targeting metabolic enzymes remains an attractive approach for treating tu... 详细信息

关键词： colorectal attractive Metabolic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Residual symmetry and interactions between solitons and periodic waves of the Drinfeld-Sokolov-Satsuma-Hirota system

引用

Communications in Theoretical Physics 2025年第1期77卷 1-10页

作者： Jie-tong Li jun Yu Xi-zhong Liu Institute of Nonlinear Science Shaoxing UniversityShaoxing 312000China

In this paper,the Drinfeld-Sokolov-Satsuma-Hirota(DSSH)system is studied by using residual symmetry and the consistent Riccati expansion(CRE)method,*** residual symmetry of the DSSH system is localized to Lie point symmetry in a properly prolonged system,based on which we get a new Bäcklund transformation for this *** symmetry reduction solutions of the DSSH system are obtained by applying the classical Lie group approach on the prolonged ***,the DSSH system proves to be CRE integrable and new interesting interaction solutions between solitons and periodic waves are generated and analyzed.

关键词： Drinfeld-Sokolov-Satsuma-Hirota system residual symmetry consistent Riccati expansion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Turbulent Agglomeration of Microparticles in a Cylinder Wake Flow Using LES-DEM:Focusing on the Effect of the Reynolds Number

引用

Journal of Thermal Science 2025年第1期34卷 34-49页

作者： WANG Shuang MU lin LI Xue XIE jun DONG Ming School of Energy and Power Engineering Dalian University of TechnologyDalian 116024China School of Optical Information and Energy Engineering Wuhan Institute of TechnologyWuhan 430205China School of Energy and Environment Shenyang Aerospace UniversityShenyang 110136China

Turbulent agglomeration is viewed as a promising technology for enhancing fine particle removal *** better understand particle transport,agglomeration behaviors,and fluid-particle interactions,we numerically explored these phenomena under cylindrical vortex wake influence using a coupled large eddy simulation and discrete element method(LES-DEM)*** validity of the LES approach was verified by comparison with available direct numerical simulation(DNS)*** adopted the Johnson-Kendall-Roberts(JKR)contact model for particle-particle *** particle dispersion and agglomeration characteristics of particles with different diameters(d_(p)=2-20μm)in the laminar and transition of shear layer(TrSL)flow regimes were *** particles were concentrated at the vortex centers,while larger particles accumulated around the *** agglomeration efficiency exhibited an M-shaped profile spanwise(y-direction).With increasing Reynolds number,the agglomeration efficiency and turbulence intensity *** particle agglomeration efficiency peaks at a certain Reynolds ***,at higher Reynolds numbers,reducing the residence time of particles in the flow field decreases the agglomeration efficiency.

关键词： microparticle particle agglomeration discrete element method large eddy simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：