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Chinese Medical Sciences Journal 2008年第4期23卷 244-248页

作者： Qing-guo Zhu Ya-kun Zhao wei Liu Hui luo Yu Qiu Zhi-zhong Gao Department of Urinary Surgery the Second Affiliated Hospital of Harbin Medical University Harbin 150086

Objective To evaluate the safety and feasibility of steroid or mycophenolate mofetil （MMF） withdrawal from tacrolimus-based immunosuppressant regimen in renal allograft recipients. Methods A cohort of 45 patients following cadaveric renal allograft transplantation were randomly divided into 3 groups based on the regimen of combination of tacrolimus, steroid, and MMF： triple therapy group, steroid withdrawal group, and MMF withdrawal group. During 2 years, survival of patients and allografts, clinical acute rejection, adverse events, hepatic and renal allograft function, and blood lipids were monitored to evaluate the safety and feasibility of steroid or MMF withdrawal after renal transplantation. Results During two-year observation, steroid or MMF was successfully withdrawn from immunosuppressant regimen based on tacrolimus without any clinical acute rejection renal allografts kept excellent function. Some adverse events among groups. Patient and graft survival rates were 100% and all the occurred and there were no significant differences Conclusion Withdrawal of steroid or MMF in low-immunological-risk renal allografts treated with tacrolimus-based immunosuppressant regimen can be achieved with no increased risk of acute rejection.

关键词： renal transplantation tacrolimus mycophenolate mofetil steroid

High gain,broadband p-WSe_(2)/n-Ge van der Waals heterojunction phototransistor with a Schottky barrier collector

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Nano Research 2023年第4期16卷 5796-5802页

作者： Shuo Li Qiang Wu Haokun Ding Songsong Wu Xinwei Cai Rui Wang jun Xiong Guangyang Lin wei Huang Songyan Chen Cheng Li Department of Physics Semiconductor Photonics Research CenterXiamen UniversityXiamen 361005China

Mixed-dimensional van der Waals(vdW)heterostructures based on two-dimensional transition metal dichalcogenides and threedimensional semiconductors have led to a new era in next-generation optoelectronics due to the high-quality interfaces and energy band complementation,especially in broadband photodetectors which can be used for all-weather navigation,object identification,***,the reported photodetectors conventionally operated in photodiode mode with low responsivity and a narrow response *** this study,we report a p-WSe_(2)/n-Ge vdW heterojunction phototransistor with a Schottky barrier collector on n-Ge for broadband *** hole/electron injection ratio from p-WSe_(2)/n-Ge heterojunction under forward bias due to their large bandgap offset renders the high photocurrent gain,while the Ge Schottky barrier limits the dark *** responsivities of the phototransistor at 1.0 V emitter-collector bias are 55,95,and 120 A·W−1 at 405,1,310,and 1,550 nm,respectively,which is superior to that of the corresponding p-WSe_(2)/n-Ge *** phototransistor shows a high photocurrent gain of 80,a specific detectivity of 1011 Jones,as well as a fast response time of 290μs at 1,550 *** results suggest that the novel phototransistor being implemented with complementary metal-oxide-semiconductor processing is an ideal strategy for high-performance broadband photodetection.

关键词： broadband van der Waals(vdW)heterojunction Schottky junction phototransistor

CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPUNCTURE PLUS MANUAL REPOSITION FOR TREATMENT OF ACUTE LUMBAR VERTEBRAL ARTICULAR DYSKINESIA

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World Journal of Acupuncture-Moxibustion 2003年第4期13卷 41-44页

作者： luo jun-fan(骆钧梵) The Second Affiliated Hospital of Jinan University Shenzhen Municipal People''s Hospital Shenzhen 518020 China

Objective: To observe the therapeutic effect of acupuncture plus manual reposition for treatment of acute lumbar vertebral articular dyskinesia for choosing a better remedy. Methods: 66 cases of acute lumbar vertebral articular dyskinesia were randomly divided into acupuncture plus manual reposition group (treatment group, n=33) and routine manual reposition group (control group, n=33). Yaotong point was punctured, when, the patient was asked to move his or her waist simultaneously. Results: After one session of treatment, of the two 33 cases in treatment and control groups, 28 (84.85%) and 20 (60.61%) were cured, 4 (12.12%) and 9 (27.27%) were improved, and 1 (3.03%) and 4 (12.12%) failed in the treatment. The therapeutic effect of treatment group was significantly superior to that of control group (P<0.05). Conclusion: Acupuncture combined with manual reposition is apparently superior to simple routine manual reposition in relieving acute lumbar vertebral articular dyskinesia.

关键词： Acute lumbar,vertebral articular dyskinesia,Acupuncture therapy, Manual reposition

Malignant adenomyoepithelioma of the breast:Two case reports and review of the literature

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World Journal of Clinical Cases 2021年第31期9卷 9549-9556页

作者： Duan-Yang Zhai Tian-Tian Zhen Xiao-Ling Zhang Jia luo Hui-Juan Shi Ya-wei Shi Nan Shao The Breast Disease Center The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina Department of Pathology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina Department of Radiology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina Department of Medical Ultrasonics The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Malignant adenomyoepithelioma(AME)of the breast is a rare tumor in which malignancy can arise from either epithelial or myoepithelial components,or from both cell *** incidence and prognosis of malignant AME of the breast are difficult to assess due to its ***,the optimal treatment for this disease is still *** SUMMARY We present two middle-aged women(48 and 56 years old)with malignant AME of the *** needle biopsy was performed before ***,breast adenoma and malignant tumors were *** preoperative diagnosis of malignant AME of the breast is still challenging for pathologists and *** patients underwent mastectomy and sentinel lymph node biopsy,both of which were negative,followed by adjuvant *** The follow-up duration of the two patients was two years and four months,*** signs of relapse or metastasis have been observed thus far.

关键词： Breast Malignant adenomyoepithelioma Imaging Immunohistochemistry Literature review Case report

Phase-transforming mechanical metamaterials with dynamically controllable shape-locking performance

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National Science Review 2023年第9期10卷 270-285页

作者： Yiding Zhong wei Tang Huxiu Xu Kecheng Qin Dong Yan Xujun Fan Yang Qu Zhaoyang Li Zhongdong Jiao Huayong Yang jun Zou State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang University School of Mechanical Engineering Zhejiang University Institute of Process Equipment College of Energy EngineeringZhejiang University

Active mechanical metamaterials with customizable structures and deformations,active reversible deformation,dynamically controllable shape-lo cking performance and stretchability are highly suitable for applications in soft robotics and flexible electronics,yet it is challenging to integrate them due to their mutual ***,we introduce a class of phase-transforming mechanical metamaterials(PMMs) that integrate the above *** arranging basic actuating units according to the designed pattern configuration and positional relationship,PMMs can customize complex and diverse structures and ***-vapor phase transformation provides active reversible large deformation while a silicone matrix offers *** contained carbonyl iron powder endows PMMs with dynamically controllable shape-lo cking performance,thereby achieving magnetically assisted shape locking and energy storing in different working *** build a theoretical model and finite element simulation to guide the design process of PMMs,so as to develop a variety of PMMs with different functions suitable for different applications,such as a programmed PMM,reconfigurable antenna,soft lens,soft mechanical memory,biomimetic hand,biomime tic flytrap and self-contained soft *** are applicable to achieve various 2D deformations and 2D-to-3D deformations,and integrate multiple properties,including customizable structures and deformations,active reversible deformation,rapid reversible shape locking,adjustable energy storing and stretchability,which could open a new application avenue in soft robotics and flexible ele ctronics.

关键词： active mechanical metamaterials shape locking energy storage liquid–vapor phase transform soft robotics

A voltammetric sensor for simultaneous determination of lead,cadmium and zinc on an activated carbon fiber rod

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Chinese Chemical Letters 2018年第1期29卷 111-114页

作者： wei-Jie Wang Yan-Ling Cai Bai-Chuan Li jun Zeng Zhi-Yong Huang Xiao-Mei Chen College of Food and Biological Engineering Jimei University

In this work, a simple, low cost and sensitive voltammetric sensor was developed for the simultaneous detection of lead （Pb2＋）, cadmium （Cd2＋）, and zinc （Zn2＋） ions based on a disposable carbon fiber rod （CFR）. The important factors to enhance the sensing property were creation of a clean surface by dealing with CFR at a high potential and electrochemical deposition of bismuth （Bi） film to improve the accumulation of heavy metal ions. The morphology and conductivity of such activated CFR was characterized by scanning electron microscopy and electrochemical impedance spectroscopy, respectively. In terms of application, differential pulse anodic stripping voltammetry （DPASV） was employed for the simultaneous detection of Pb2＋, Cd2＋, and Zn2＋ on Bi film-coated activated CFR. Experimental parameters, such as the pH value of buffer solution, stirring speed and enrichment factors were optimized. Under optimal conditions, the DPASV peak currents showed good linear relationships with Pb2＋, Cd2＋ and Zn2＋ concentrations in the range of 0.5-2.25 μg/L, 0.5-4.0 μg/L and 1.0- 4.0 μg/L with detection limits of 0.1, 0.3 and 1.0 μg/L （SIN = 3）, respectively. Finally, the proposed analysis system was successfully utilized for the simultaneous detection of Pb2＋, Cd2＋, and Zn2＋ contents in rice samples. This study indicated that Bi film-coated activated CFR based DPASV sensor can be a promising and reliable tool for rapid analysis of emergency Dollution affairs of heavv metal ions in food.

关键词： Carbon fiber rodBismuth filmDifferential pulse anodic stripping voltammetryHeavy metal ionsSensor

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高炉渣改良填料大型直剪试验分析

中国公路学报 2020年第2期33卷 64-72页

作者：黄大维徐长节刘香许有俊罗文俊华东交通大学铁路环境振动与噪声教育部工程研究中心江西南昌330013 华东交通大学土木工程国家实验教学示范中心江西南昌330013 华东交通大学江西省岩土工程基础设施安全与控制重点实验室江西南昌330013 内蒙古科技大学建筑与土木工程学院内蒙古包头014010

将原状高炉渣掺拌粉煤灰分层碾压并重锤夯实作为换填地基的填料,进行分层取样后,以处于干、湿状态下各层土样的混和土作为试样开展大型直剪试验。为了探究高炉渣改良填料的直剪力学特性,以及现有大型直剪仪的不足,对不同法向应力作用下... 详细信息

将原状高炉渣掺拌粉煤灰分层碾压并重锤夯实作为换填地基的填料,进行分层取样后,以处于干、湿状态下各层土样的混和土作为试样开展大型直剪试验。为了探究高炉渣改良填料的直剪力学特性,以及现有大型直剪仪的不足,对不同法向应力作用下试样的抗剪强度、法向加载板的竖向位移进行了量测,并对试验过程中剪力与剪切位移曲线特性、剪切盒张开状态、完成直剪试验后试样的破碎状态进行了分析。结果表明:因细颗粒不足以填充粗颗粒之间的孔隙,含水量对改良填料力学指标影响很小,改良填料表现为良好的水稳定性;高炉渣改良填料在法向应力小于150kPa时几乎没有黏聚力,而在法向应力大于150kPa时表现出咬合黏聚力;高炉渣混合料直剪试验过程中法向应力越大,初期剪缩量越大,后期剪胀量越小,发生剪胀时对应的剪切位移也越大;在法向应力大于150kPa后,直剪试验的剪胀量有了较大程度的减小,此时剪切面的形成主要以剪切区粗颗粒的剪碎与断裂为主。最后,考虑到现有大型直剪仪随着剪切位移的增加,理论剪切面上的剪切应力与法向应力分布越来越不均匀,且有效剪切面积逐渐减小,为此对大型直剪仪提出了改进建议,使有效剪切面面积保持恒定不变,测试结果与实际情况更加接近,可提高粗颗粒土剪切强度的测试精度。

关键词：道路工程高炉渣直剪试验内摩擦角咬合黏聚力直剪仪

A palaeoearthquake event and its age revealed by the travertine layer along the Litang fault in the southeastern margin of the Qinghai-Tibetan plateau

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Earthquake Research Advances 2023年第3期3卷 53-62页

作者： Yao Yang Mingjian Liang Chao Ma jun Li Hualiang Shen Fang Du Song luo Shao Liu Xuelian Rui Sichuan Earthquake Agency Chengdu610041China College of Earth Sciences Chengdu University of TechnologyChengdu610059China Zhejiang Earthquake Agency Hangzhou310013China Chengdu Geological Survey Center China Geological SurveyChengdu610081China

The Litang fault(LTF),located in the southeast of the Qinghai-Tibetan Plateau,is known for its high level of present-day seismicity,whereas its Pleistocene activity has been scarcely *** study focused on a tract of banded travertine deposits precipitated from thermal waters along the NW–SE-trending LTF *** role of travertine deposits in recording neotectonic activity has been studied by identifying their internal *** soft-sediment deformation structures observed within the banded travertines include micro folds,liquefied breccia,and liquefied *** deformed structures,which are restricted to a single unit separated unconformably by undeformed layers,can be traced for tens of meters,indicating that they were formed by seismic shaking triggered by LTF *** deformation of the banded travertine layers is attributed to the combined effects of seismic shaking,liquefaction,and fluidization,and it can be related to a paleo earthquake event with a magnitude of MS>*** U-series ages obtained from the banded travertine deposits perturbed by the earthquakes are in the range of 130.59–112.94 ka,indicating an important fault-assisted neotectonic activity that occurred during the Middle–Late *** of such structures,in combination with the use of U-series dating methods,can yield a reliable timing of neotectonic activity and provide new evidence for under-standing the seismotectonic setting of the Litang area.

关键词： Travertine Paleoearthquake Soft-sediment deformation U-series dating Litang fault

Additively Manufactured Flexible Electronics with Ultrabroad Range and High Sensitivity for Multiple Physiological Signals'Detection

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Research 2022年第4期2022卷 707-717页

作者： Huanhuan Feng Yaming Liu Liang Feng Limeng Zhan Shuaishuai Meng Hongjun Ji Jiaheng Zhang Mingyu Li Peng He weiwei Zhao jun wei Sauvage Laboratory for Smart Materials Shenzhen Key Laboratory of Flexible Printed Electronics TechnologyHarbin Institute of Technology(Shenzhen)China State Key Laboratory of Advanced Welding and Joining(Shenzhen) Harbin Institute of Technology(Shenzhen)China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyChina

Flexible electronics can be seamlessly attached to human skin and used for various purposes, such as pulse monitoring, pressure measurement, tensile sensing, and motion detection. Despite their broad applications, most flexible electronics do not possess both high sensitivity and wide detection range simultaneously;their sensitivity drops rapidly when they are subjected to even just medium pressure. In this study, ultrabroad-range, high-sensitivity flexible electronics are fabricated through additive manufacturing to address this issue. The key to possess high sensitivity and a wide detection range simultaneously is to fabricate flexible electronics with large depth-width ratio circuit channels using the additive manufacturing inner-rinsing template method. These electronics exhibit an unprecedented high sensitivity of 320 kPa^(−1) over the whole detection range, which ranges from 0.3 to 30,000 Pa (five orders of magnitude). Their minimum detectable weight is 0.02 g (the weight of a fly), which is comparable with human skin. They can stretch to over 500% strain without breaking and show no tensile fatigue after 1000 repetitions of stretching to 100% strain. A highly sensitive and flexible electronic epidermal pulse monitor is fabricated to detect multiple physiological signals, such as pulse signal, breathing rhythm, and real-time beat-to-beat cuffless blood pressure. All of these signals can be obtained simultaneously for detailed health detection and monitoring. The fabrication method does not involve complex expensive equipment or complicated operational processes, so it is especially suitable for the fabrication of large-area, complex flexible electronics. We believe this approach will pave the way for the application of flexible electronics in biomedical detection and health monitoring.

关键词： fatigue additive stretching

A Fast Melting Release Method in Free-Fall Equivalence Principle Test

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Chinese Physics Letters 2001年第2期18卷 172-174页

作者： WU Zi-Gang WANG Dian-Hong luo jun ZHOU Ze-Bing NIE Yu-Xin ZHANG Yuan-Zhong Department of Physics Huazhong University of Science and TechnologyWuhan 430074 Department of Mechanical and Electronic Engineering China University of GeosciencesWuhan 430074 Institute of Physics Chinese Academy of SciencesBeijing 100080 Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100080

A fast melting release method for the free-fall equivalence principle test using laser interferometry is *** primary experiment result shows that the uncertainty of the differential release time could be controlled at... 详细信息

关键词： release satis interferometry