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Biliary stent combined with iodine-125 seed strand implantation in malignant obstructive jaundice

World Journal of Clinical Cases 2021年第4期9卷 801-811页

作者： Hui-Wen Wang Xiao-Jing Li Shi-Jie Li jun-rong lu Dong-Feng He Department of Interventional Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina

BACKGROUND Malignant obstructive jaundice is mainly caused by *** a few patients are indicated for surgical resection,and the 3-year survival rate is<50%.For patients who are not eligible for surgery,biliary stent pla... 详细信息

BACKGROUND Malignant obstructive jaundice is mainly caused by *** a few patients are indicated for surgical resection,and the 3-year survival rate isluate the safety and efficacy of biliary stent combined with 125I seed strand implantation in malignant obstructive *** We enrolled 67 patients between January 2016 and june 2018 with malignant obstructive jaundice and randomized them into a biliary stent combined with 125I seed strand treatment(combined)group(n=32)and biliary stent(control)group(n=35).All patients underwent enhanced computed tomography and magnetic resonance imaging and were tested for biochemical and cancer *** patients underwent pathological examination before *** patients were followed up by telephone or clinical *** liver function improvement,postoperative complications,stent patency time,and survival time were compared between the two *** risk factors were *** Technical success was achieved in all patients in both *** liver function improved significantly in all patients(total bilirubin,direct bilirubin,alanine aminotransferase,and aspartate aminotransferase decreased significantly in all patients,the P values were less than 0.05).There was no significant difference in preoperative or postoperative indexes between the two groups for changes in total bilirubin(P=0.147),direct bilirubin(P=0.448),alanine aminotransferase(P=0.120),and aspartate aminotransferase(P=0.387)between the two *** median stent patency time of the combined group was 9.0±1.4 mo[95%confidence interval(CI):6

关键词： Biliary stent 125I Obstructive jaundice Malignant tumor Clinical research Surgery

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From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua lu jun Shen Xin Zhang Lingcong Chao Liang Chen Ding Zhang Tao Wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

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A New Threshold Signature Scheme Using Self-Certified Public Keys

A New Threshold Signature Scheme Using Self-Certified Public...

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The 1st Chinese Conference on Trusted Computing and Information Security

作者： SHAO jun, lu rong-xing, CAO Zhen-fu Department of Computer Science and Engineering, Shanghai Jiaotong University, Shanghai 200030, China

＜正＞ To prevent active attack, we propose a new threshold signature scheme using self-certified public keys, which makes use of hash function and discrete logarithm problem. The scheme has less commutnication and co... 详细信息

关键词： self-certified threshold signature public key cryptosystems

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FTIR及CLSM对转基因杨木细胞壁木质素含量及微区分布研究

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光谱学与光谱分析 2017年第11期37卷 3404-3408页

作者：刘苍伟苏明垒周贤武赵荣军吕建雄王玉荣中国林业科学研究院木材工业研究所北京100091 中国林业科学研究院林业新技术研究所北京100091

通过木质素基因工程能够有效降低杨木细胞壁木质素含量,从而改善人工林杨树作为木质纤维材料的利用现状。选取C3H基因活性抑制表达的转基因杨树和其对照组杨树为实验材料,利用傅里叶红外光谱(FTIR)技术快速表征C3H基因表达活性降低后幼... 详细信息

通过木质素基因工程能够有效降低杨木细胞壁木质素含量,从而改善人工林杨树作为木质纤维材料的利用现状。选取C3H基因活性抑制表达的转基因杨树和其对照组杨树为实验材料,利用傅里叶红外光谱(FTIR)技术快速表征C3H基因表达活性降低后幼龄杨木细胞壁木质素的含量,并结合激光共聚焦显微镜(CLSM)和组织化学染色技术原位表征木质素含量微区分布变化规律。结果表明转基因杨树与对照组杨树红外谱图的形状和特征峰数目、位置基本一致,表明C3H基因活性降低并未改变杨木细胞壁主要化学成分及结构,但I_(1 508)/I_(1 379),I_(1 508)/I_(1 425)和I_(1 508)/I_(1 740)木质素特征峰高度比值结果表明转基因杨木木质素含量下降了8.2%~9.5%,峰强度的区别说明C3H基因活性抑制表达能够改变杨木细胞壁上木质素等化学组分含量;CLSM观察发现转基因杨木木质素微区分布含量均为纤维细胞角隅>复合胞间层>次生壁,与对照组木质素呈现相同的沉积规律,且转基因杨木细胞壁木质素浓度低于对照组杨木;组织化学染色的结果同样表明杨木S单体木质素均匀分布于纤维细胞壁上,而G单体木质素微区沉积规律为纤维细胞角隅>复合胞间层>次生壁,进一步揭示了C3H基因活性的降低并没有改变转基因杨木G和S木质素单体的沉积规律,但对其纤维和导管壁上木质素单体含量分布有一定影响。

关键词：转基因杨木木质素傅里叶红外光谱激光共聚焦

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei Zhang Yubao lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming Zhang Bin Liu Limin rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

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用胶溶法制备超微粒二氧化钛

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重庆大学学报（自然科学版） 1989年第4期12卷 10-15页

作者：张启超杨隽吕荣中许定刊重庆大学应用化学系重庆大学冶金及材料工程系

本文介绍了用胶溶法制备透明性超微粒二氧化钛的方法和原理,对产品进行了x—射线衍射和电镜分析,并检测了它在有机溶剂中的分散性。

关键词：超微粒胶溶法二氧化钛

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Understanding the local structure and thermophysical behavior of Mg-La liquid alloys via machine learning potential

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 439-449页

作者： Jia Zhao Taixi Feng Guimin lu National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China Joint International Laboratory for Potassium and Lithium Strategic Resources East China University of Science and TechnologyShanghai 200237China

The local structure and thermophysical behavior of Mg-La liquid alloys were in-depth understood using deep potential molecular dynamic(DPMD) simulation driven via machine learning to promote the development of Mg-La alloys. The robustness of the trained deep potential(DP) model was thoroughly evaluated through several aspects, including root-mean-square errors(RMSEs), energy and force data, and structural information comparison results;the results indicate the carefully trained DP model is reliable. The component and temperature dependence of the local structure in the Mg-La liquid alloy was analyzed. The effect of Mg content in the system on the first coordination shell of the atomic pairs is the same as that of temperature. The pre-peak demonstrated in the structure factor indicates the presence of a medium-range ordered structure in the Mg-La liquid alloy, which is particularly pronounced in the 80at% Mg system and disappears at elevated temperatures. The density, self-diffusion coefficient, and shear viscosity for the Mg-La liquid alloy were predicted via DPMD simulation, the evolution patterns with Mg content and temperature were subsequently discussed, and a database was established accordingly. Finally, the mixing enthalpy and elemental activity of the Mg-La liquid alloy at 1200 K were reliably evaluated,which provides new guidance for related studies.

关键词： magnesium-lanthanum liquid alloys local structure macroscopic properties thermodynamic behavior deep potential mo-lecular dynamic simulation

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Staged dendrite suppression for high safe and stable lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： jun Jiang Zhenjie lu Yanwen Ding Shujun Liu Zhijie Qi Tian Tang Yunfan Zhang Zhiyuan Ma Jingwen Sun Liang Xue Wenyao Zhang Pan Xiong Xin Wang junwu Zhu Yongsheng Fu Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Lithium-sulfur batteries Staged dendrite suppression Shuttle effect Surface-negatively-charged nanodiamond

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新生儿低血糖与早期神经发育迟缓的相关性分析

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中国医刊 2017年第2期52卷 61-64页

作者：廖柳华林俊荣卢莉敏广东省惠州市中心人民医院儿科广东惠州516001

目的探讨新生儿低血糖与早期神经发育迟缓的相关性。方法选取本院2015年2月至2016年2月收治的80例低血糖新生儿,发生早期神经发育迟缓的20例为研究组,余下60例为对照组,对可能造成早期神经发育迟缓的相关诱因进行单因素分析,有显著差异... 详细信息

目的探讨新生儿低血糖与早期神经发育迟缓的相关性。方法选取本院2015年2月至2016年2月收治的80例低血糖新生儿,发生早期神经发育迟缓的20例为研究组,余下60例为对照组,对可能造成早期神经发育迟缓的相关诱因进行单因素分析,有显著差异的因素行多因素logistic回归分析,筛选出独立性危险因素。结果单因素分析可见低血糖新生儿的胎龄、出生体质量、妊娠期糖尿病、新生儿窒息、开奶时间、惊厥、血糖水平、低血糖持续时间、脑电图(electroencephalogram,EGG)检查与早期神经发育迟缓有关(P<0.05);多因素logistic回归分析可见新生儿窒息、惊厥、低血糖水平、低血糖持续时间超过24小时、脑电图检查异常为新生儿低血糖发生早期神经发育迟缓的独立性危险因素(P<0.05)。结论新生儿窒息、惊厥、低血糖水平、低血糖持续时间超过24小时、脑电图检查异常为新生儿低血糖患儿发生早期神经发育迟缓的独立性危险因素,临床上应当重视此类危险因素,并尽早干预。

关键词：新生儿低血糖早期神经发育迟缓相关性分析

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双螺杆挤压机操作参数对膨化水产饲料物性的影响

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水产学报 2007年第3期31卷 379-384页

作者：俞微微刘俊荣王勇路红波谢智芬大连水产学院食品工程系大连水产学院食品工程系辽宁大连116023

利用Clextral BC-45型双螺杆挤压机对豆饼粉、鱼粉和玉米粉的混合原料进行挤压蒸煮生产水产饲料。通过改变螺杆转速、进料速率和进水速率来生产具有不同物性的水产饲料,并对所得到的饲料进行膨化度、堆积密度和水中稳定性指数的测定,同... 详细信息

利用Clextral BC-45型双螺杆挤压机对豆饼粉、鱼粉和玉米粉的混合原料进行挤压蒸煮生产水产饲料。通过改变螺杆转速、进料速率和进水速率来生产具有不同物性的水产饲料,并对所得到的饲料进行膨化度、堆积密度和水中稳定性指数的测定,同时对挤出物的浮性进行了观察。应用二次回归通用旋转设计进行试验方案设计及试验结果分析,建立回归方程来描述操作参数与膨化度、堆积密度、水中稳定性指数的关系。研究结果表明,螺杆转速、进料速率和进水速率均与膨化度和堆积密度有显著的相关关系,而与水中稳定性指数的相关关系不显著。应用所建立的回归方程可预测和控制挤压产品的膨化度与堆积密度。操作参数与水中稳定性指数的关系需进一步研究。

关键词：双螺杆挤压蒸煮操作参数物性二次回归通用旋转设计

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