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Journal of Thermal Science 2025年第1期34卷 34-49页

作者： WANG Shuang MU lin li Xue XIE jun DONG Ming School of Energy and Power Engineering Dalian University of Technology School of Optical Information and Energy Engineering Wuhan Institute of Technology School of Energy and Environment Shenyang Aerospace University

Turbulent agglomeration is viewed as a promising technology for enhancing fine particle removal *** better understand particle transport,agglomeration behaviors,and fluid-particle interactions,we numerically explored these phenomena under cylindrical vortex wake influence using a coupled large eddy simulation and discrete element method（LES-DEM） *** validity of the LES approach was verified by comparison with available direct numerical simulation（DNS） *** adopted the Johnson-Kendall-Roberts（JKR） contact model for particle-particle *** particle dispersion and agglomeration characteristics of particles with different diameters（dp=2-20 μm） in the laminar and transition of shear layer（TrSL） flow regimes were *** particles were concentrated at the vortex centers,while larger particles accumulated around the *** agglomeration efficiency exhibited an M-shaped profile spanwise（y-direction）.With increasing Reynolds number,the agglomeration efficiency and turbulence intensity *** particle agglomeration efficiency peaks at a certain Reynolds ***,at higher Reynolds numbers,reducing the residence time of particles in the flow field decreases the agglomeration efficiency.

关键词： discrete element method large eddy simulation microparticle particle agglomeration

Investigation of Edge Fluctuation Characteristics on the HL-2A Tokamak

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Southwestern Institute of Physics Annual Report

Southwestern Institute of Physics Annual Report 2005年第1期 23-24页

作者： HONG Wenyu YAN Longwen qian jun li qiang ZHAO Kaijun CHENG jun LUO Cuiwen XU Zhengyu HUANG Yuan

The edge plasma fluctuation characteristics are studied by the fast reciprocating scanning 6-probes in the boundary region. These probes can measure edge plasma temperature, density, poloidal electric field, radial electric field, Reynolds stress, and their profiles in once discharges. Measurement results are used to analyze plasma confinement, turbulent fluctuations and their correlation characteristics during multi-shot pellet injection （MPI） , supersonic molecular beam injection （SMB1） and electron cyclotron resonant heating （ ECRH ） discharges.

关键词： Fast-scanning probe Multi-shot pellet injection Supersonic molecular beam injection

Epigenetic regulation of the inflammatory response in stroke

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Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi liang Fei Yang Zixiao li qian li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment

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Targets capture by distributed active swarms via bio-inspired reinforcement learning

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 210-221页

作者： Kun Xu Yue li jun Sun Shuyuan Du Xinpeng Di Yuguang Yang Bo li Institute of Biomechanics and Medical Engineering Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua University Institute of Nuclear and New Energy Technology Tsinghua University Shanghai Aerospace Control Technology Institute Shanghai Key Laboratory of Aerospace Intelligent Control Technology College of Automation Engineering Nanjing University of Aeronautics and Astronautics

Natural swarms arranged from cells to herds are usually decentralized but display intriguing collective intelligence in coordinating individuals across large scales to efficiently achieve their common goals. Learning from nature may provide new strategies for controlling collective dynamics of synthetic swarms to accomplish specific functions. Here, we present a bioinspired computational framework that steers distributed active swarms to collectively capture and merge targets via reinforcement learning. We exploit collective milling structures of natural herds to cage the targets, and adopt a switching control policy inspired by sperms' chiral dynamics to optimize the trajectories of individuals, through which the active swarms can selforganize to enclose single or multiple distant targets in a dynamical, adaptive and scalable manner. There exists a critical swarm size, beyond which the excessive competition between agents would generate large mechanical forces, leading to capture instability but enabling the transition from short-distance to long-distance merging capture of multiple targets. This work provides physical insights into distributed active swarms and could offer a multilevel, decentralized strategy toward controlling swarm robotics in wide applications such as bio-medical devices, machine immunity, and target clearance.

关键词： swarm intelligence robotics multi-tasks artificial intelligence bionics

Experimental Observation of the Edge and Divertor Plasma in HL-2A

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Southwestern Institute of Physics Annual Report

Southwestern Institute of Physics Annual Report 2006年第1期 46-47页

作者： HONG Wenyu YAN Longwen qian jun li qiang PAN Yudong LUO Cuiwen XU Zhengyu PAN li YANG Qingwei HUANG Yuan

In this experiment, the electrostatic probes positioned on the divertor plates and at the edge of main vacuum chamber, which are used to measure plasma parameters. All these parameters are used to investigate the edge turbulence and correlative characteristic. A large number of experimental results suggest that the confinement improvement is related to the increasing rotation velocity and to the decreasing edge fluctuation.

关键词：等离子体环流器二号A装置核反应核技术

Improving performance of parts storage through line-cell conversion

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Improving performance of parts storage through line-cell con...

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

2009中国控制与决策会议

作者： jun Gong,qian li,Jiafu Tang Institute of Systems Engineering,Northeastern University,Shenyang 110004,CHINA

The cell assembly system is a new innovation of production strategies in the *** are many system performances needed to evaluate for the line-cell conversion,parts storage is one of them,In this paper,an overview of line-cell conversion to generate insights of the innovation is presented at first,and then a mathematical model is proposed to describe the performance of parts storage in a cell assembly *** last,some numerical simulation experiments are designed and executed to evaluate the system performance of parts storage.

关键词： Cell assembly systems Assembly line systems Parts storage Cross-trained line-cell conversion

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Science China life Sciences 2025年第1期68卷 300-302页

作者： Ze-Min lin Mai Xiang Wen-Hui Wei Shu-Hui Fan li Chen Jie Wang Xiao-qian Yang Chun-Hao Yang Shi-jun He Jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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Thickness and sp3 bond modulation of（Ti/tetrahedral amorphous carbon）_n multilayer coatings

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Tungsten 2025年第1期7卷 152-160页

作者： Zhi-jun Xie Jia-lin li ling Gong Xiang-li Zhong Hong-Jia Song Jin-Bin Wang National-Provincial Laboratory of Special Function Thin Film Materials School of Materials Science and Engineering Xiangtan University

The durability of wear-resistant tetrahedral amorphous carbon（ta-C） coatings is intimately linked to their thickness and the concentration of *** enhance the lifespan of the coatings,we have prepared a multilayer coating consisting of alternating layers of Ti and ta-C,denoted as（Ti/ta-C）_n,using arc ion plating.A multi-layer structure in conjunction with stage cooling is employed to enhance the thickness and promote *** results indicate that the ID/IGvalue,representing the ratio of the intensity of the D peak to that of the G peak in Raman spectroscopy,decreases from 0.85 when no stage cooling is applied to 0.35 when stage cooling is employed,suggesting an enhancement in the fraction of sp3bonds within the *** obtained（Ti/ta-C）_n multilayer coating without peeling off has a maximum thickness of 1.14 μm,which is almost double that of the ta-C coating single layer *** the same time,the coating has a low coefficient of friction,down to 0.069,and maintains excellent friction properties with a wear rate of 3.4×10-6mm3·N-1·*** results conclusively show that the preparation technology can enhance both thickness and sp3bonding in ta-C coatings,significantly expanding their utility across tools,molds,and precision engineering components.

关键词： Arc ion plating Multilayer structure sp3 bond Ta-C coating Wear resistance

First observation results of Macao Science Satellite-1 on lightning-induced electron precipitation

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Science China Earth Sciences 2025年第1期68卷 1-10页

作者： Yongping WANG Yixin SUN Qiugang ZONG Gaopeng LU Xudong GU Ze-jun HU Bin li Key Laboratory for Polar Science Ministry of Natural Resources Polar Research Institute of China Institute of Space Physics and Applied Technology Peking University State Key Laboratory of Lunar and Planetary Science Macau University of Science and Technology School of Earth and Space Sciences University of Science and Technology of China School of Electronic Information Wuhan University

The Medium-energy Electron Spectrometers(MES) is a space-borne instrument onboard Macao Science Satellite-1(MSS-1) dedicated to monitoring the typical charged particle radiation characteristics in the satellite orbit and the process of their occurrence and development, including short bursts of lightning-induced electron precipitation(LEP).This paper presents the first results of the LEP measurements by the MSS-1.47 LEP events are identified with the routine operation for 3 months since satellite launch, all within the range of 1.5lightning discharges are definitively geo-located for these LEP *** LEP events occur within lightning and consist of 40–300 keV electrons.A preliminary observation result indicates that, with medium-energy electron detectors, MSS-1can present in-situ observations of large regions of enhanced background precipitation and reveal their fine spatiotemporal characteristics and spectral *** collaborative VLF ground-based measurements at the Great Wall Station, Antarctica also have a good correspondence with LEP measurements of *** observations also imply that lightning activity has a modulation effect on the energetic electron energy-spatial structure.

关键词： lightning-induced electron precipitation Inner radiation belts Energetic electrons Macao Science Satellite-1

离子液体[Bmim][BF4]中卟啉的三线态动力学

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物理化学学报 2017年第11期33卷 2191-2198页

作者：马仁君郭前进李博轩夏安东中国科学院化学研究所北京分子科学国家实验室光化学重点实验室北京100190 中国科学院大学北京100049

室温离子液体由于其几乎不挥发、稳定性突出、良好的电化学性能以及结构与性能的可设计性等优点,在诸多领域得到了深入的研究和广泛的应用。与传统的普通溶剂不同,离子液体的本质特点之一是其内部的微观结构具有微不均匀性。本文通过对... 详细信息

室温离子液体由于其几乎不挥发、稳定性突出、良好的电化学性能以及结构与性能的可设计性等优点,在诸多领域得到了深入的研究和广泛的应用。与传统的普通溶剂不同,离子液体的本质特点之一是其内部的微观结构具有微不均匀性。本文通过对四苯基卟啉(TPP)分子在离子液体[Bmim][BF_4]中的三线态动力学研究,发现在激光作用下,TPP的三线态寿命由2.95μs显著增加到184μs。进一步分析表明,这一现象很可能是由于离子液体的微结构在激光诱导下发生变化,被激光场或者离子诱导极化的氧气分子在离子液体微不均匀性环境中发生重新分布而引起的。

关键词：离子液体微不均匀性结构分子探针三线态动力学卟啉

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