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W-Grbner basis and monomial ideals under polynomial composition

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Applied Mathematics(A Journal of Chinese Universities) 2011年第3期26卷 287-294页

作者： LI Dong-mei LIU Jin-wang LIU Wei-jun School of Mathematical Sciences and Computing Technology Central South University Changsha410075 China School of Mathematics and Computing Sciences Hunan University of Science and Technology Xiangtan 411201 China

The notion of weakly relatively prime and W-Gr6bner basis in K[x1, x2,…, xn] are given. The following results are obtained： for polynomials fl, f2, ..., fm, {f1^λ1, f2^λ2,…, fm^λm} is a GrSbner basis if and only if f1, f2, …, fm are pairwise weakly relatively prime with λ1, λ2, …, λm arbitrary non-negative integers; polynomial composition by θ = （θ1,θ2, …, θn） commutes with monomial-Grobner bases computation if and only if θ1, θ2, , θm are pairwise weakly relatively prime.

关键词： W-Grobner basis weakly relatively prime polynomial composition.

基于多元文化理论在设计住院患者健康教育执行单中的研究

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中华全科医学 2017年第1期15卷 103-105页

作者：孙孝君姚红梅王宁辰郑俊宁波市鄞州人民医院护理部浙江宁波315040

目的探讨运用多元文化理论在设计健康教育执行单中的应用和效果,以提高健康教育效果和对护理工作的满意度。方法将300例收入宁波市鄞州人民医院的住院患者按住院日的单双日随机分为对照组和干预组,各150例,2组在住院期间均接受健康教育... 详细信息

目的探讨运用多元文化理论在设计健康教育执行单中的应用和效果,以提高健康教育效果和对护理工作的满意度。方法将300例收入宁波市鄞州人民医院的住院患者按住院日的单双日随机分为对照组和干预组,各150例,2组在住院期间均接受健康教育。对照组护士采用传统方式以口头形式实施健康宣教;干预组责任护士运用以多元文化理论为基础设计的健康教育执行单,对患者进行多元文化评估,再实施健康宣教并及时评价。在患者即将出院前由指定人员按规定的要求以口头提问形式对患者的健康教育知晓程度进行评估,并发放护理满意度调查问卷。统计数据分别按χ~2检验和秩和检验进行分析,对比2组患者对健康教育的知晓情况和对护理工作的满意度。结果对比2组患者健康教育调查情况,能正确回答者干预组人数高于对照组人数,2组比较差异有统计学意义(P<0.05);调查2组满意度显示,干预组和对照组患者总体满意的人数分别为146例和126例,z=-7.044,P<0.001,差异有统计学意义。结论运用多元文化理论设计的健康教育执行单,不但能提高护士对健康教育的执行力,而且在健康教育实施中,护士运用与患者文化背景相一致的多元文化护理,更能贴近患者的身心需求,提高了患者对健康宣教的认知程度和对护理工作的满意度,护士的主观能动性也得到充分的发挥。

关键词：多元文化理论住院患者健康教育执行单健康宣教

Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation

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Journal of Molecular Cell Biology 2017年第4期9卷 338-349页

作者： Bo wang Xing Fu mei-jun Zhu Min Du Advanced Innovation Center for Food Nutrition and Human Health China Agricultural University Beijing 100094 China Department of Animal Sciences Washington State University Pullman WA 99164 USA School of Food Science Washington State University Pullman WA 99164 USA

Retinoic acid （RA）, a bioactive metaboUte of vitamin A, is a critical mediator of cell differentiation. RA blocks adipogenesis, but mechanisms remain to be established. ZFP423 is a key transcription factor maintaining white adipose identity. We found that RA inhibits Zfp423 expression and adipogenesis via blocking DNA demethylation in the promoter of Zfp423, a process mediated by growth arrest and DNA-damage-inducible protein alpha （GADD45A）. RA induces the partnering between retinoic acid receptor （PAR） and tumor suppressor inhibitor of growth protein 1 （ING1）, which prevents the formation of GADD45A and ING1 complex necessary for locus-specific Zfp423 DNA demethylation. In vivo, vitamin A supplementation prevents obesity, downregulates Godd45a expression, and reduces GADD45A binding and DNA demethylation in the Zfp423 promoter. Inhibition of Zfp423 expres- sion due to PA contributes to the enhanced brown adipogenesis. In summary, PA inhibits white adipogenesis by inducing PAR and ING1 interaction and inhibiting Godd45a expression, which prevents GADD45A-mediated DNA demethylation.

关键词： vitamin A retinoic acid Gadd45α adipogenesis demethylation Zfp423

Omics Approaches for Exploring Pneumoconiosis:A Review

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Biomedical and Environmental Sciences 2021年第1期34卷 71-82页

作者： LUO Ya QI Xian mei PANG jun Ling wang Jing wang Chen State Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical SciencesDepartment of PathophysiologyPeking Union Medical CollegeBeijing 100730China State Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical SciencesDepartment of PhysiologyPeking Union Medical CollegeBeijing 100730China

Pneumoconiosis,a fatal lung disease caused by dust inhalation and deposition,is one of the leading occupational diseases worldwide[1].The dust is primarily inorganic particles,such as silica particles,coal dust,and asbestos *** the diameter of dust is less than 5μm,it is defined as‘respirable dust’that can easily reach the distal airways and alveoli[2].

关键词： lung diseases occupational

Effect of interface anisotropy on tilted growth of eutectics:A phase field study

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Chinese Physics B 2022年第10期31卷 563-571页

作者： mei-Rong Jiang jun-Jie Li Zhi-jun wang Jin-Cheng wang State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China

Interfacial energy anisotropy plays an important role in tilted growth of eutectics. However, previous studies mainly focused on the solid-solid interface energy anisotropy, and whether the solid-liquid interface energy anisotropy can significantly affect the tilted growth of eutectics still remains unclear. In this study, a multi-phase field model is employed to investigate both the effect of solid-liquid interfacial energy anisotropy and the effect of solid-solid interfacial energy anisotropy on tilted growth of eutectics. The findings reveal that both the solid-liquid interfacial energy anisotropy and the solid-solid interfacial energy anisotropy can induce the tilted growth of eutectics. The results also demonstrate that when the rotation angle is within a range of 30°-60°, the growth of tilted eutectics is governed jointly by the solid-solid interfacial energy anisotropy and the solid-liquid interfacial energy anisotropy;otherwise, it is mainly controlled by the solid-solid interfacial energy anisotropy. Further analysis shows that the unequal pinning angle at triple point caused by the adjustment of the force balance results in different solute-diffusion rates on both sides of triple point. This will further induce an asymmetrical concentration distribution along the pulling direction near the solid-liquid interface and the tilted growth of eutectics. Our findings not only shed light on the formation mechanism of tilted eutectics but also provide theoretical guidance for controlling the microstructure evolution during eutectic solidification.

关键词： tilted eutectics interfacial energy anisotropy multi-phase field model

Structure and Fluid Transportation Performance of Faults in the Changxing-Feixianguan Formation, Xuanhan County, Northeastern Sichuan Basin

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Acta Geologica Sinica(English Edition) 2014年第3期88卷 865-877页

作者： DU Chunguo wang Jianjun ZHANG jun wang Ping XUE mei ZHOU Huayao Research Institute of Petroleum Exploration and Development Weatherford (China) Energy Services Co. Ltd PetroChina International Exploration and Development Company China University of Petroleum

On the basis of field observations, microscopic thin-sections and laboratory data analysis of ten faults in Xuanhan County area, northeastern Sichuan Basin, central China, the internal and megascopic structures and tectonite development characteristics are mainly controlled by the geomechanical quality in brittle formation of the Changxing-Feixianguan Formation. The fluid transportation performance difference between the faults formed by different geomechanics or different structural parts of the same fault are controlled by the mcgascopic structure and tectonite development characteristics. For instance, the extension fault structure consists of a tectonite breccia zone and an extension fracture zone. Good fluid transportation performance zones are the extension fracture zone adjacent to the tectonite breccia zone and the breccia zone formed at the early evolutionary stage. The typical compression fault structure consists of a boulder-clay zone or zones of grinding gravel rock, compression foliation, tectonite lens, and dense fracture development. The dense fracture development zone is the best fluid transporting area at a certain scale of the compression fault, and then the lens, grinding gravel rock zone and compression foliation zones are the worst areas for hydrocarbon migration. The typical tensor-shear fault with a certain scale can be divided into boulder-clay or grinding gravel rock zones of the fault, as well as a pinnate fractures zone and a derivative fractures zone. The grinding gravel rock zone is the worst one for fluid transportation. Because of the fracture mesh connectivity and better penetration ability, the pinnate fractures zone provides the dominant pathway for hydrocarbon vertical migration along the tensor-shear fault.

关键词： Structural geology fault tectonite hydrocarbon migration fluid transportationperformance Sichuan Basin

Multi-Level Feature Aggregation-Based Joint Keypoint Detection and Description

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Computers, Materials & Continua 2022年第11期73卷 2529-2540页

作者： jun Li Xiang Li Yifei Wei mei Song Xiaojun wang Beijing Key Laboratory of Work Safety Intelligent Monitoring School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing100876China Dublin City University Dublin9Ireland

Image keypoint detection and description is a popular method to find pixel-level connections between images,which is a basic and critical step in many computer vision *** existing methods are far from optimal in terms of keypoint positioning accuracy and generation of robust and discriminative *** paper proposes a new end-to-end selfsupervised training deep learning *** network uses a backbone feature encoder to extract multi-level feature maps,then performs joint image keypoint detection and description in a forward *** the one hand,in order to enhance the localization accuracy of keypoints and restore the local shape structure,the detector detects keypoints on feature maps of the same resolution as the original *** the other hand,in order to enhance the ability to percept local shape details,the network utilizes multi-level features to generate robust feature descriptors with rich local shape information.A detailed comparison with traditional feature-based methods Scale Invariant Feature Transform(SIFT),Speeded Up Robust Features(SURF)and deep learning methods on HPatches proves the effectiveness and robustness of the method proposed in this paper.

关键词： Multi-scale information keypoint detection and description artificial intelligence

Online Rail Fastener Detection Based on YOLO Network

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Computers, Materials & Continua 2022年第9期72卷 5955-5967页

作者： jun Li Xinyi Qiu Yifei Wei mei Song Xiaojun wang Beijing Key Laboratory of Work Safety Intelligent Monitoring School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing100876China Dublin City University Dublin9Ireland

Traveling by high-speed rail and railway transportation have become an important part of people’s life and social *** is the basic equipment of railway transportation,and its performance directly affects the service lifetime of railway lines and *** anomaly detection of rail fasteners is in a priority,while the traditional manual method is extremely inefficient and dangerous to ***,this paper introduces efficient computer vision into the railway detection system not only to locate the normal fasteners,but also to recognize the fasteners *** be more specific,this paper mainly studies the rail fastener detection based on improved You can Only Look Once version 5(YOLOv5)network,and completes the real-time classification of fastener *** improved YOLOv5 network proposed contains five sections,which are Input,Backbone,Neck,Head Detector and a read-only Few-shot Example Learning *** main purpose of this project is to improve the detection precision and shorten the detection ***,the rail fastener detection system proposed in this paper is confirmed to be superior to other advanced *** model achieves on-line fastener detection by completing the“sampling-detection-recognition-warning”cycle of a single sample before the next image is ***,the mean average precision of model reaches 94.6%.And the model proposed reaches the speed of 12 ms per image in the deployment environment of NVIDIA GTX1080Ti GPU.

关键词： Fastener detection deep learning state recognition real-time classification

Expression of CTB-human Insulin(BA) Fusion Protein in Gynostemma Pentapyhllum Makino Callus Cells and Its Hypoglycemic Effect in Mice

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Chemical Research in Chinese Universities 2010年第5期26卷 773-779页

作者： wang Ya-jun QI Feng-chun HAO Shu-mei wang Chun-yi SUI Bo SHENG jun College of Life Science Jilin University Changchun 130012 P R. China Changchun Institute of Biological Products Changchun 130062 P R. China Changchun University of Science and Technology Changchun 130022 P. R. China Changchun Keygen Biological Products Co. Ltd. Changchun 130021 P R. China Yunnan Agricultural University Kunming 650201 P. R. China

The plant expression vector of choleratoxin B subunit（CTB）-human insulin（BA） fusion protein pBI121/（CTB-BA） was constructed first and then the Gynostemma Pentapyhllum Makino callus cell line that could express CTB-human insulin fusion protein was constructed and its hypoglycemic effect was evaluated in mice. The plant expression vector pBl 121/（CTB-BA） was digested with both BamI and SacI. Agrobacterium tumerfaciens strain LBA4404 was transformed with previously constructed recombinant plasmid pBI121/（CTB-BA） via the freeze thawing method, then CTB-BA gene was integrated to G Pentapyhllum Makino callus cells by co-culturing the cells with the transformed LBA4404 strain. The transformed G Pentapyhllum Makino callus cells were identified by DNA sequence assey and RT-PCR. The expressed product was identified by western-blot and its amount was tested by ELISA kit and its blood sugar decreasing effect was tested in mice. The sequences of synthetic CTB and human insulin genes（BA） were completely identical to those designed. Restriction map proved that the length of gene fragment in- serted into expression vector pBI121 was consistent with that expected. The sequence of genomic DNA of expressed product was completely identical to that designed. The result of RT-PCR was consistent with that expected. The expressed product showed a specific band with a relative molecular mass of 17000 by Western-blot. The human insulin expression amount was 6.03 μIU/mL according to the ELISA result. The animal test showed that only the G Pentapyhllum Makino callus cell line itself showed activity in decreasing the blood sugar of mice, however, the activity of the transformed G Pentapyhllum Makino callus cells was much higher, The plant expression vector pBI121/（CTB-BA） was constructed and expressed in the G Pentapyhllum Makino callus cells successfully for the first time. The trans- formed G Pentapyhllum Makino callus cells showed high activity in decreasing the blood sugar of mice. This stu

关键词： Human insulin peptide without C pcptide Choleratoxin B subunit G Pentapyhllum Makino callus cells