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Transactions of Nonferrous Metals Society of China 2020年第12期30卷 3210-3225页

作者： jun-jie xiong Hong YAN School of Mechanical and Electrical Engineering Nanchang UniversityNanchang 330031China Key Laboratory of Light Alloy Preparation and Processing in Nanchang City Nanchang 330031China

Microstructure and mechanical properties of ADC12 composites reinforced with graphene nanoplates(GNPs)prepared by high-intensity ultrasonic assisted casting were *** results indicated that high-intensity ultrasound can promote the uniform distribution of GNPs in the melt,resulting in refining theα(Al)phase and Si *** optimal addition of GNPs was 0.9 wt.%,and the optimal ultrasonic time was 12 *** tensile strength,the yield strength and the hardness of the composite produced under the optimal parameters were 256.8 MPa,210.6 MPa and HV 126.0,respectively,which increased by 30.5%,42.7%,and 34.8%compared with those of the matrix,*** adding the GNPs,the fracture mechanism gradually turned from a brittle fracture to a ductile *** good interface and distribution allowed GNPs to play the role in fine grain strengthening,dislocation strengthening and load transfer strengthening effectively.

关键词： ADC12 composite graphene nanoplate(GNP) casting microstructure mechanical properties

Urinary trypsinogen-2 for diagnosing acute pancreatitis:a meta-analysis

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Hepatobiliary & Pancreatic Diseases International 2013年第4期12卷 355-362页

作者： Tao Jin Wei Huang Kun Jiang jun-jie xiong Ping Xue Muhammad A Javed Xiao-Nan Yang Qing Xia Sichuan Provincial Pancreatitis Center Department of Integrated Traditional Chinese and Western Medicine West China Hospital Sichuan University NIHR Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital University of LiverpoolLiverpool L69 3BX UK Department of Hepato-Biliary-Pancreatic Surgery West China Hospital Sichuan University

BACKGROUND: Currently, serum amylase and lipase are the most popular laboratory markers for early diagnosis of acute pancreatitis with reasonable sensitivity and specificity. Urinary trypsinogen-2 (UT-2) has been increasingly used but its clinical value for the diagnosis of acute pancreatitis and post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis has not yet been systematically assessed. DATA SOURCES: A comprehensive search was carried out using PubMed (MEDLINE), Embase, and Web of Science for clinical trials, which studied the usefulness of UT-2 as a diagnostic marker for acute pancreatitis. Sensitivity, specificity and the diagnostic odds ratios (DORs) with 95% confidence interval (CI) were calculated for each study and were compared with serum amylase and lipase. Summary receiver-operating curves were conducted and the area under the curve (AUC) was evaluated. RESULTS: A total of 18 studies were included. The pooled sensitivity and specificity of UT-2 for the diagnosis of acute pancreatitis were 80% and 92%, respectively (AUC=0.96, DOR=65.63, 95% CI: 31.65-139.09). The diagnostic value of UT-2 was comparable to serum amylase but was weaker than serum lipase. The pooled sensitivity and specificity for the diagnosis of post-ERCP pancreatitis were 86% and 94%, respectively (AUC=0.92, DOR=77.68, 95% CI: 24.99-241.48).CONCLUSIONS: UT-2 as a rapid test could be potentially used for the diagnosis of post-ERCP pancreatitis and to an extent, acute pancreatitis. Further studies are warranted to confirm these results.

关键词： urinary trypsinogen-2 acute pancreatitis endoscopic retrograde cholangiopancreatography diagnostic odds ratios meta-analysis

Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy

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World Journal of Gastroenterology 2013年第46期19卷 8731-8739页

作者： jun-jie xiong Quentin M Nunes Wei Huang Samir Pathak Ai-Lin Wei Chun-Lu Tan Xu-Bao Liu Department of Hepato-Biliary-Pancreatic Surgery West China HospitalSichuan University NIHR Liverpool Pancreas Biomedical Research Unit Department of Molecular and Clinical Cancer MedicineRoyal Liverpool University HospitalUniversity of Liverpool Sichuan Provincial Pancreatitis Center Department of Integrated Traditional Chinese and Western MedicineWest China HospitalSichuan University

AIM:To investigate the effect of preoperative biliary drainage(PBD)in jaundiced patients with hilar cholangiocarcinoma(HCCA)undergoing major liver ***:An observational study was carried out by reviewing a prospectively maintained database of HCCA patients who underwent major liver resection for curative therapy from January 2002 to December *** were divided into two groups based on whether PBD was performed:a drained group and an undrained *** baseline characteristics,preoperative factors,perioperative and short-term postoperative outcomes were compared between the two *** factors for postoperative complications were also analyzed by logistic regression test with calculating OR and 95%***:In total,78 jaundiced patients with HCCA underwent major liver resection:32 had PBD prior to operation while 46 did not have *** two groups were comparable with respect to age,sex,body mass index and ***,there was no significant difference in the total bilirubin(TBIL)levels between the drained group and the undrained group at admission(294.2±135.7 vs 254.0±63.5,P=0.126).PBD significantly improved liver function,reducing not only the bilirubin levels but also other liver *** preoperative TBIL level was significantly lower in the drained group as compared to the undrained group(108.1±60.6 vs 265.7±69.1,P=0.000).The rate of overall postoperative complications(53.1%vs 58.7%,P=0.626),reoperation rate(6.3%vs 6.5%,P=1.000),postoperative hospital stay(16.5 vs 15.0,P=0.221)and mortality(9.4%vs 4.3%,P=0.673)were similar between the two *** addition,there was no significant difference in infectious complications(40.6%vs 23.9%,P=0.116)and noninfectious complications(31.3%vs 47.8%,P=0.143)between the two *** and multivariate analyses revealed that preoperative TBIL>170μmol/L(OR=13.690,95%CI:1.275-147.028,P=0.031),Bismuth-Corlette classification(OR=0.013,95%CI:0.001-0.166,P=0.001)and extended

关键词： Obstructive jaundice Hilar cholangiocar-cinoma Preoperative biliary drainage Major hepatec-tomy Surgical outcome

Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis

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World Journal of Gastroenterology 2013年第28期19卷 4607-4615页

作者： Wei Huang Kiran Altaf Tao Jin jun-jie xiong Li Wen Muhammad A Javed Marianne Johnstone Ping Xue Christopher M Halloran Qing Xia Sichuan Provincial Pancreatitis Center Department of Integrated Traditional Chinese and Western Medicine West China Hospital Sichuan University NIHR Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital University of Liverpool Liverpool L69 3GA United Kingdom Department of Hepato-Biliary-Pancreatic Surgery West China Hospital Sichuan University

AIM: To undertake a meta-analysis on the value of urinary trypsinogen activation peptide (uTAP) in predicting severity of acute pancreatitis on admission.METHODS: Major databases including Medline, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in the Cochrane Library were searched to identify all relevant studies from January 1990 to January 2013. Pooled sensitivity, specificity and the diagnostic odds ratios (DORs) with 95%CI were calculated for each study and were compared to other systems/biomarkers if mentioned within the same study. Summary receiver-operating curves were conducted and the area under the curve (AUC) was evaluated.RESULTS: In total, six studies of uTAP with a cut-off value of 35 nmol/L were included in this meta-analysis. Overall, the pooled sensitivity and specificity of uTAP for predicting severity of acute pancreatitis, at time of admission, was 71% and 75%, respectively (AUC = 0.83, DOR = 8.67, 95%CI: 3.70-20.33). When uTAP was compared with plasma C-reactive protein, the pooled sensitivity, specificity, AUC and DOR were 0.64 vs 0.67, 0.77 vs 0.75, 0.82 vs 0.79 and 6.27 vs 6.32, respectively. Similarly, the pooled sensitivity, specificity, AUC and DOR of uTAP vs Acute Physiology and Chronic Health Evaluation II within the first 48 h of admission were found to be 0.64 vs 0.69, 0.77 vs 0.61, 0.82 vs 0.73 and 6.27 vs 4.61, respectively.CONCLUSION: uTAP has the potential to act as a stratification marker on admission for differentiating disease severity of acute pancreatitis.

关键词： Acute pancreatitis Urinary trypsinogen activation peptide C-reactive protein Acute Physiology and Chronic Health Evaluation II score Meta-analysis

Prophylactic intra-peritoneal drain placement following pancreaticoduodenectomy:A systematic review and metaanalysis

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World Journal of Gastroenterology 2015年第8期21卷 2510-2521页

作者： Yi-Chao Wang Peter Szatmary Jing-Qiang Zhu jun-jie xiong Wei Huang Ilias Gomatos Quentin M Nunes Robert Sutton Xu-Bao Liu Department of Thyroid and Breast Surgery West China Hospital Sichuan University NIHR Liverpool Pancreas Biomedical Research Unit Royal Liverpool University Hospital University of Liverpool Department of Pancreatic Surgery West China Hospital Sichuan University

AIM:To conduct a meta-analysis comparing outcomes after pancreaticoduodenectomy(PD)with or without prophylactic ***:Relevant comparative randomized and nonrandomized studies were systemically searched based on specific inclusion and exclusion *** outcomes were compared between patients with and those without routine *** odds ratios(OR)with 95%CI were calculated using either fixed effects or random effects ***:One randomized controlled trial and four non-randomized comparative studies recruiting 1728patients were *** without prophylactic drainage after PD had significantly higher mortality(OR=2.32,95%CI:1.11-4.85;P=0.02),despite the fact that they were associated with fewer overall complications(OR=0.62,95%CI:0.48-0.82;P=0.00),major complications(OR=0.75,95%CI:0.60-0.93;P=0.01)and readmissions(OR=0.77,95%CI:0.60-0.98;P=0.04).There were no significant differences in the rates of pancreatic fistula,intraabdominal abscesses,postpancreatectomy hemorrhage,biliary fistula,delayed gastric emptying,reoperation or radiologic-guided drains between the two ***:Indiscriminate abandonment of intraabdominal drainage following PD is associated with greater mortality,but lower complication *** randomized trials should compare routine vs selective drainage.

关键词： Pancreaticoduodenectomy Drain Metaanalysis Morbidi

Roux-en-Y versus BillrothⅠreconstruction after distal gastrectomy for gastric cancer:A meta-analysis

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World Journal of Gastroenterology 2013年第7期19卷 1124-1134页

作者： jun-jie xiong Kiran Altaf Muhammad A Javed Quentin M Nunes Wei Huang Gang Mai Chun-Lu Tan Rajarshi Mukherjee Robert Sutton Wei-Ming Hu Xu-Bao Liu Department of Hepato-Biliary-Pancreatic Surgery West China HospitalSichuan University NIHR Liverpool Pancreas Biomedical Research Unit Royal Liverpool University HospitalUniversity of LiverpoolLiverpool L69 3GAMerseyside CountyUnited Kingdom

AIM: To conduct a meta-analysis to compare Roux-en-Y (R-Y) gastrojejunostomy with gastroduodenal Billroth?I?(B-I) anastomosis after distal gastrectomy (DG) for gastric cancer.METHODS: A literature search was performed to identify studies comparing R-Y with B-I?after DG for gastric cancer from January 1990 to November 2012 in Medline, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in The Cochrane Library. Pooled odds ratios (OR) or weighted mean differences (WMD) with 95%CI were calculated using either ?xed or random effects model. Operative outcomes such as operation time, intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture, bile re?ux, remnant gastritis, re?ux esophagitis, dumping symptoms, delayed gastric emptying and hospital stay were the main outcomes assessed. Meta-analyses were performed using RevMan 5.0 software (Cochrane library).RESULTS: Four randomized controlled trials (RCTs) and 9 non-randomized observational clinical studies (OCS) involving 478 and 1402 patients respectively were included. Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile re?ux (OR 0.04, 95%CI: 0.01, 0.14; P < 0.00?001) and remnant gastritis (OR 0.43, 95%CI: 0.28, 0.66; P = 0.0001), however needing a longer operation time (WMD 40.02, 95%CI: 13.93, 66.11; P = 0.003). Meta-analysis of OCS also revealed R-Y reconstruction had a lower incidence of bile re?ux (OR 0.21, 95%CI: 0.08, 0.54; P = 0.001), remnant gastritis (OR 0.18, 95%CI: 0.11, 0.29; P < 0.00?001) and re?ux esophagitis (OR 0.48, 95%CI: 0.26, 0.89; P = 0.02). However, this reconstruction method was found to be associated with a longer operation time (WMD 31.30, 95%CI: 12.99, 49.60; P = 0.0008).CONCLUSION: This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-I?reconstruction post DG. However there is a need for further adequately powered, well-desig

关键词： Gastric cancer Distal gastrectomy Roux-en-Y Billroth I Reconstruction Meta-analysis

Laparoscopic vs open total gastrectomy for gastric cancer:A meta-analysis

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World Journal of Gastroenterology 2013年第44期19卷 8114-8132页

作者： jun-jie xiong Quentin M Nunes Wei Huang Chun-Lu Tan Neng-Wen Ke Si-Ming Xie Xun Ran Hao Zhang Yong-Hua Chen Xu-Bao Liu Department of Hepato-Biliary-Pancreatic Surgery West China HospitalSichuan University NIHR Liverpool Pancreas Biomedical Research Unit Royal Liverpool University HospitalUniversity of Liverpool Liverpool L69 3GA United Kingdom

AIM:To conduct a meta-analysis comparing laparoscopic total gastrectomy(LTG)with open total gastrectomy(OTG)for the treatment of gastric ***:Major databases such as Medline(PubMed),Embase,Academic Search Premier(EBSCO),Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials(CENTRAL)in The Cochrane Library were searched for studies comparing LTG and OTG from January 1994 to May *** endpoints were operative,postoperative and oncological *** outcomes included operative time and intraoperative blood *** recovery included time to first fatus,time to first oral intake,hospital stay and analgesics *** complications comprised morbidity,anastomotic leakage,anastomotic stenosis,ileus,bleeding,abdominal abscess,wound problems and *** outcomes included positive resection margins,number of retrieved lymph nodes,and proximal and distal resection *** pooled effect was calculated using either a fixed effects or a random effects ***:Fifteen non-randomized comparative studies with 2022 patients were included(LTG-811,OTG-1211).Both groups had similar short-term oncological outcomes,analgesic use(WMD-0.09;95%CI:-2.39-2.20;P=0.94)and mortality(OR=0.74;95%CI:0.24-2.31;P=0.61).However,LTG was associated with a lower intraoperative blood loss(WMD-201.19 mL;95%CI:-296.50--105.87 mL;P<0.0001)and overall complication rate(OR=0.73;95%CI:0.57-0.92;P=0.009);fewer wound-related complications(OR=0.39;95%CI:0.21-0.72;P=0.002);a quicker recovery of gastrointestinal motility with shorter time to frst fatus(WMD-0.82;95%CI:-1.18--0.45;P<0.0001)and oral intake(WMD-1.30;95%CI:-1.84--0.75;P<0.00001);and a shorter hospital stay(WMD-3.55;95%CI:-5.13--1.96;P<0.0001),albeit with a longer operation time(WMD 48.25 min;95%CI:31.15-65.35;P<0.00001),as compared with ***:LTG is safe and effective,and may offer some advantages over OTG in the treatment of gastric cancer.

关键词： Gastric cancer Laparoscopic total gastrectomy Laparoscopic assisted total gastrectomy Open total gastrectomy Meta-analysis

跑步荷载下大跨结构的竖向振动加速度反应谱研究

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工程力学 2017年第3期34卷 173-181页

作者：陈隽熊杰程李果同济大学土木工程防灾国家重点实验室上海200092 同济大学土木工程学院上海200092

采用无线测力鞋垫实测了24人次372条跑步荷载,计算了每条时程所对应的单自由度系统的加速度反应谱,取每位测试者所有的计算反应谱曲线的包络线为其代表谱线,在分析所有代表谱线特点的基础上提出了设计反应谱的形式及其数学表达式,包含... 详细信息

采用无线测力鞋垫实测了24人次372条跑步荷载,计算了每条时程所对应的单自由度系统的加速度反应谱,取每位测试者所有的计算反应谱曲线的包络线为其代表谱线,在分析所有代表谱线特点的基础上提出了设计反应谱的形式及其数学表达式,包含六个部分:三个平台段以及它们之间的连接线。由试验数据的分析确定了不同阻尼比和保证率下各部分设计谱参数的取值,并讨论了结构跨度、跑步步距、高阶振型和边界条件对反应谱的影响,提出了不同谱代表值之间的转换关系。该文给出了设计反应谱的详细使用步骤并通过工程实例验证了其可行性。

关键词：大跨工程结构振动舒适度跑步荷载设计反应谱分段模型

Structural and Electrical Characters of Ba_(0.6)Sr_(0.4)TiO_3/La_(0.5)Sr_(0.5)CoO_3 Thin Films by Plus Laser Deposition

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Journal of Electronic Science and Technology of China 2007年第4期5卷 303-307页

作者： Wen-Feng Qin jun Zhu jie xiong Jin-Long Tang Xiao Feng State Key Laboratory of Electronic Thin Film and Integrated Devices University of Electronic Science and Technology of China （UESTC） Chcngdu 610054 China

Epitaxial Ba0.6Sr0.4TiO3 （BST） thin films were deposited on LaAlO3 （LAO） substrates with the conductive metallic oxide La0.5 Sr0.5CoO3 （LSCO） film as a bottom electrode by pulsed laser deposition （PLD）. X-ray diffraction 0-20 andФ scan showed that the epitaxial relationship of BST/LSCO /LAO was [001] BST// [001] LSCO//[001] LAO. The atomic force microscope （AFM） revealed a smooth and crack-free surface of BST films on LSCO-coated LAO substrate with the average grain size of 120 nm and the RMS of 1.564 nm for BST films. Pt/BST/LSCO capacitor was fabricated to perform Capacitance-Voltage measurement indicating good insulating characteristics. For epitaxial BST film, the dielectric constant and dielectric loss were determined as 471 and 0.03, respectively. The tunabilty was 79.59% and the leakage current was 2.63×10^-7 A/cm^2 under an applied filed of 200 kV/cm. Furthermore, it was found that epitaxial BST （60/40） fdms demonstrate well-behaved ferroelectric properties with the remnate polarization of 6.085μC/cm^2 and the coercive field of 72 kV/cm. The different electric properties from bulk BST （60/40） materials with intrinsic paraelectric characteristic are attributed to the interface effects.

关键词： BST electrode LSCO thin film.

Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma

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World Journal of Gastroenterology 2012年第45期18卷 6657-6668页

作者： jun-jie xiong Kiran Altaf Muhammad A Javed Wei Huang Rajarshi Mukherjee Gang Mai Robert Sutton Xu-Bao Liu Wei-Ming Hu Department of Hepato-Biliary-Pancreatic Surgery West China HospitalSichuan University Liverpool NIHR Pancreas Biomedical Research Unit Royal Liverpool University HospitalUniversity of LiverpoolLiverpool L69 3GAUnited Kingdom Pancreatic Diseases Research Group Department of Integrated Traditional and Western MedicineWest China HospitalSichuan University

AIM:To conduct a meta-analysis to determine the safety and efficacy of laparoscopic liver resection(LLR) and open liver resection(OLR) for hepatocellular carcinoma(HCC).METHODS:PubMed(Medline),EMBASE and Science Citation Index Expanded and Cochrane Central Register of Controlled Trials in the Cochrane Library were searched systematically to identify relevant comparative studies reporting outcomes for both LLR and OLR for HCC between January 1992 and February *** authors independently assessed the trials for inclusion and extracted the ***-analysis was performed using Review Manager Version 5.0 software(The Cochrane Collaboration,Oxford,United Kingdom).Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed effects(Mantel-Haenszel method) or random effects models(DerSimonian and Laird method).Evaluated endpoints were operative outcomes(operation time,intraoperative blood loss,blood transfusion requirement),postoperative outcomes(liver failure,cirrhotic decompensation/ascites,bile leakage,postoperative bleeding,pulmonary complications,intraabdominal abscess,mortality,hospital stay and oncologic outcomes(positive resection margins and tumor recurrence).RESULTS:Fifteen eligible non-randomized studies were identified,out of which,9 high-quality studies involving 550 patients were included,with 234 patients in the LLR group and 316 patients in the OLR *** was associated with significantly lower intraoperative blood loss,based on six studies with 333 patients [WMD:-129.48 mL;95%CI:-224.76-(-34.21) mL;P = 0.008].Seven studies involving 416 patients were included to assess blood transfusion requirement between the two *** LLR group had lower blood transfusion requirement(OR:0.49;95%CI:0.26-0.91;P = 0.02).While analyzing hospital stay,six studies with 333 patients were *** in the LLR group were found to have shorter hospital stay [WMD:-3.19 d;95%CI:-4.09-(-2.28) d;P < 0.00001] than their OLR

关键词： Hepatocellular carcinoma Laparoscopy Open liver resection Hepatectomy Meta-analysis