检索结果-南通市图书馆

Current status of percutaneous coronary intervention of chronic total occlusion

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第8期13卷 589-602页

作者： jun-bo ge Department of Cardiology Zhongshan HospitalFudan UniversityShanghai 200032China

This paper describes the current status of percutaneous coronary intervention (PCI) for totally occluded coronary arteries. Chronic total occlusion is associated with 10%-20% of all PCI procedures. Results show that opening an occluded vessel, especially one supplying a considerable area of myocardium, may be beneficial for a patient's angina relief and heart function. We describe the devices used currently in re-canalization such as new wires, microcatheters (including Tonus and Cosair) and intravascular ultrasound guidance. Different techniques to improve the success rate and reduce complications are discussed in detail.

关键词： Percutaneous coronary intervention Chronic total occlusion Retrograde approach

An unexpected electrocardiogram sign of subacute left ventricular free wall rupture: Its early awareness may be lifesaving

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2020年第2期11卷 117-119页

作者： Hong-yi Wu Ju-ying Qian Qi-bing Wang jun-bo ge Shanghai Institute of Cardiovascular Diseases Department of Cardiology Zhongshan Hospital Fudan University

BACKGROUND:Post-infarct left ventricular free wall rupture(LVFWR)is not always an immediately catastrophic complication.The rupture can be subacute,allowing time for diagnosis and intervention.Accordingly,early recognition of the entity may be lifesaving.METHODS:We present an electrocardiogram(ECG)change pattern in two cases,which was erroneously attributed to ischemia.Two women in their 80s were admitted to our institute after experiencing the sudden onset of chest pain.They were managed as anterior ST-segment elevation myocardial infarction without reperfusion treatment.Unfortunately,they experienced a recurrence of severe chest pain with cardiogenic shock during hospitalisation.The ECG recorded at that time showed a ST-segment re-elevation in infract-related leads.RESULTS:The two cases were regrettably received a misjudgement of reinfarction at first,and one of the patients even was administrated with tirofi ban.Afterwards the diagnosis of subacute LVFWR was made through antemortem echocardiography.CONCLUSION:New ST-segment elevation(STE)in infarct-associated leads,coupled with recurrence of chest pain and new-onset hypotension,may constitute the premonitory signs of a subacute LVFWR.

关键词： Myocardial infarction Myocardial rupture Electrocardiogram Diagnosis

Nine-month Angiographic and Two-year Clinical Follow-up of Novel Biodegradable-polymer Arsenic Trioxide-eluting Stent Versus Durable-polymer Sirolimus-eluting Stent For Coronary Artery Disease

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第6期128卷 768-773页

作者： Li Shen Wei Yang Jia-Sheng Yin Xue-bo Liu Yi-ZheWu Ai-jun Sun Ju-Ying Qian jun-bo ge Department of Cardiology Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital Fudan University Shanghai 200032 China Department of Cardiology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China Department of Cardiology East Hospital Tongji University School of Medicine Shanghai 200120 China

Background:Despite great reduction of in-stent restenosis,first-generation drug-eluting stents (DESs) have increased the risk of late stent thrombosis due to delayed endothelialization.Arsenic trioxide,a natural substance that could inhibit cell proliferation and induce cell apoptosis,seems to be a promising surrogate of sirolimus to improve DES performance.This randomized controlled trial was to evaluate the efficacy and safety of a novel arsenic trioxide-eluting stent (AES),compared with traditional sirolimus-eluting stent (SES).Methods:Patients with symptoms of angina pectoris were enrolled and randomized to AES or SES group.The primary endpoint was target vessel failure (TVF),and the second endpoint includes rates of all-cause death,cardiac death or myocardial infarction,target lesion revascularization (TLR) by telephone visit and late luminal loss (LLL) at 9-month by angiographic follow-up.Results:From July 2007 to 2009,212 patients were enrolled and randomized 1 ∶1 to receive either AES or SES.At 2 years of follow-up,TVF rate was similar between AES and SES group (6.67％ vs.5.83％,P =0.980).Frequency of all-cause death was significantly lower in AES group (0 vs.4.85％,P =0.028).There was no significant difference between AES and SES in frequency of TLR and in-stent restenosis,but greater in-stent LLL was observed for AES group (0.29 ± 0.52 mm vs.0.1 0 ± 0.25 mm,P =0.008).Conclusions:After 2 years of follow-up,AES demonstrated comparable efficacy and safety to SES for the treatment of de novo coronary artery lesions.

关键词： Arsenic Trioxide Coronary Artery Disease Drug-eluting Stent

Nonhypertensive male with multiple paragangliomas of the heart and neck:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第22期8卷 5707-5714页

作者： Qi Wang Zhe-Yong Huang jun-bo ge Xian-Hong Shu Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesShanghai 200032China

BACKGROUND Paraganglioma is a rare disease that can be lethal if undiagnosed.Thus,quick recognition is very important.Cardiac paragangliomas are found in patients who have hypertension.The classic symptoms are the triad of headaches,palpitations,and profuse sweating.We describe a very rare case of multiple paragangliomas of the heart and bilateral carotid artery without hypertension and outline the management strategies for this disease.CASE SUMMARY A 46-year-old man presented with the chief complaint of recently recurrent chest pain with a history of hemangioma of the bilateral carotid artery that had been surgically removed.He was found to have an intracardiac mass in the right atrioventricular groove and underwent successful excision.The final pathology demonstrated that the intracardiac mass was a cardiac paraganglioma,and the patient had an increased level of normetanephrine in the blood.The pathology and immunohistochemistry results showed that the bilateral carotid masses were also paragangliomas.During the 3 mo follow-up period,the patient did not experience recurrence of chest pain.CONCLUSION To our knowledge,this is the first case of multiple paragangliomas of the heart and neck without hypertension.This rare disease can be lethal if left undiagnosed.Thus,quick recognition is very important.The key to the diagnosis of cardiac paraganglioma is the presence of typical symptoms,including headaches,palpitations,profuse sweating,hypertension,and chest pain.Radiology can demonstrate the intracardiac mass.It is important to determine the levels of normetanephrine in the blood.The detection of genetic mutations is also recommended.Surgical resection is necessary to treat the disease and obtain pathological evidence.

关键词： Chest pain Intracardiac mass Cardiac paraganglioma Normetanephrine Pathological evidence Case report

Morphological Evidence of Telocytes in Mice Aorta

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第3期128卷 348-352页

作者： Hong-Qi Zhang Shan-Shan Lu Ting Xu Yan-Ling Feng Hua Li jun-bo ge Department of Anatomy Histology and Embryology Shanghai Medical College Fudan University Shanghai 200032 China Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai Shanghai 200032 China Department of Pathology Shanghai Public Health Clinical Center Shanghai 201508 China Institute of Biochemistry and Cell Biology Shanghai Institutes of Biological Sciences Chinese Academy of Sciences Shanghai 200031 China Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital Fudan University Shanghai 200032 China institutes of Biomedical Sciences Fudan University Shanghai 200032 China

Background： Telocytes （TCs） are a novel type of interstitial cells, which have been recently described in a large variety of cavitary and noncavitary organs. TCs have small cell bodies, and remarkably thin, long, and moniliform prolongations called telopodes （Tps）. Until now, TCs have been found in various loose connective tissues surrounding the arterioles, venules, and capillaries, but as a histological cellular component, whether TCs exist in large arteries remains unexplored. Methods： TCs were identified by transmission electron microscope in the aortic arch of male C57BL/6 mice. Results： TCs in aortic arch had small cell bodies （length： 6.06-13.02 μm： width： 1.05-4.25 μm） with characteristics of specific long （7.74-39.05 μm）, thin, and moniliform Tps; TCs distributed in the whole connective tissue layer of tunica adventitia： TCs in the innermost layer of tunica adventitia, located at the juncture between media and adventitia, with their long axes oriented parallel to the outer elastic membrane： and TCs in outer layers oftunica adventitia, were embedded among transverse and longitudinal oriented collagen fibers,forming a highly complex three-dimensional meshwork. Moreover, desmosomes were observed, serving as pathways connecting neighboring Tps. In addition, vesicles shed from the surface of TCs into the extracellular matrix, participating in some biological processes. Conclusions： TCs in aorta arch are a newly recognized complement distinct from other interstitial cells in large arteries, such as fibroblasts. And further biologically functional correlations need to be elucidated.

关键词： Aorta＇ Telocyte： Telopode

Transcatheter Aortic Valve Implantation Assisted with Microcatheter： A New Method to Avoid Coronary Artery Obstruction

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第6期128卷 740-744页

作者： Xiang Chen Guo-jun Chu Fei-Yu Wang Yu-Feng Zhu Ben Zhang Xian-Xian Zhao Yong-Wen Qin jun-bo ge Department of Cardiology Zhongshan Hospital Fudan UniversLty Shanghai 200032 China Department of Cardiology Changhai Hospital Second Military Medical University Shanghai 200043 China Department of Cardiothoracic Surgery.Guangzhou general Hospitar of Guangzhou Mifltary Areal Guangzhou Guangdong 510010 China3Department of Cardiothoracic Surgery.Guangzhou General Hospital of Guangzhou Military Area Guangzhou Guangdong 510010 China Xiang Chen and Guo-Jun Chu contributed equally to this study

Background:Lack of fluoroscopic landmarks can make valve deployment more difficult in patients with absent aortic valve (AV)calcification.The goal of this article was to evaluate the feasibility and effectiveness oftranscatheter implantation of a valved stent into the AV position of a goat,assisted with a microcatheter which provides accurate positioning of coronary artery ostia to help valved stent deployment.Methods:The subjects were 10 healthy goats in this study.A microcatheter was introduced into the distal site of right coronary artery (RCA)through femoral artery sheath.A minimal thoracic surgery approach was used to access the apex of the heart.The apex of the left ventricle was punctured; a delivery catheter equipped with the valved stent was introduced over a stiffguidewire into the aorta arch.We could accurately locate the RCA ostia through the microcatheter placed in the RCA under fluoroscopy.After correct valve position was confirmed,the valved stent was implanted after rapid inflation of the balloon.The immediate outcome of the function of the valved stents was evaluated after implantation.Results:All ten devices were successfully implanted into the AV position of the goats.Immediate observation after the procedure showed that the valved stents were in the desired position after implantation by angiography,echocardiogram.No obstruction of coronary artery ostia occurred,and no moderate to severe aortic regurgitation was observed.Conclusions:When the procedure of transcatheter implantation of a balloon-expandable valved stent into the AV position of goats is assisted with microcatheter positioning coronary artery ostia,the success rate of operation can be increased in those with noncalcified AV.

关键词： Aortic Valve Replacement Stent Disposition Stent Migration Percutaneous

Long-term follow-up of antithrombotic management patterns in patients with acute coronary syndrome in China

在线全文

学校读者我要写书评

暂无评论

Journal of geriatric Cardiology 2020年第5期17卷 246-255,I0002-I0004页

作者： Xiao-Ning HAN Shu-Bin QIAO jun-bo ge Ya-Ling HAN Ji-Yan CHEN Zu-Yi YUAN bo YU Jie JIANG Yong HUO Department of Cardiology Peking University First HospitalBeijingChina National Center for Cardiovascular Diseases Fuwai HospitalBeijingChina Department of Cardiology Zhongshan Hospital Affiliated to Fudan UniversityGuangzhouChina Department of Cardiology the General Hospital of Shenyang MilitaryShenyangChina Department of Cardiology Guangdong General HospitalGuangzhouChina Department of Cardiology the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anChina Department of Cardiology the Second Affiliated Hospital of Harbin Medical UniversityHarbinChina

Objective To describe the long-term antithrombotic management patterns(AMPs)and clinical outcomes of Chinese patients with acute coronary syndrome(ACS).Methods This was an observational,multicenter,longitudinal cohort extension study of Chinese patients who had completed the EPICOR Asia 2-year follow-up study post-hospitalization for an ACS event.Changes in AMP and clinical outcomes for up to 5 years post-ACS event were evaluated.Results Overall,2334 patients with ACS were enrolled at 49 sites.The mean age was 61.6 years and 76.3%were men.By study end,2093 patients completed the 3-year follow-up.At baseline(2 years post-ACS event),72.4%of patents received one antiplatelet(AP)medication,with aspirin being the preferred one.A small proportion of patients(21.5%)was treated with two or more APs(2+AP),and even fewer patients(6.1%)did not receive any AP medication at baseline.Upon study completion,the proportion of patients without AP therapy increased to 13.6%,while the percentage of patients on one AP and 2+AP decreased to 69.3%and 17.1%,respectively.Numerically,a higher incidence of clinical events(composite of all-cause mortality,myocardial infarction,stroke)was observed for the 2+AP(13.2%)subgroup than for the no AP(10.5%)and one AP(8.6%)subgroups.Furthermore,the 2+AP subgroup exhibited the greatest number of bleeding events,outpatient visits,and hospitalization rates.Unlike myocardial infarction or stroke,bleeding events prompted an adjustment in AMP.Conclusion Most patients in China received at least one AP medication up to 5 years after an ACS event.

关键词： Acute coronary syndrome Antithrombotic agents Antithrombotic management patterns Observational study Real-world

A benign course of sinus node artery occlusion after stenting at proximal right coronary artery

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2021年第16期134卷 2000-2002页

作者： Hong-bo Yang Yerkintay Guliya Ya-Nan Song Jia-Tian Cao Qi-Bing Wang Ju-Ying Qian Zhe-Yong Huang jun-bo ge Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesShanghai 200032China.

To the Editor:The sinus node artery(SNA)can be occluded during the percutaneous coronary intervention(PCI),which produces bradycardia.Previous studies showed a high incidence of SNA occlusion(SNO).Improvements in stent design and anti-thrombotic strategies have decreased branch occlusion.Here,we investigated the results of this procedure in our center.The incidence of SNO was 7.0%.The percentage of diameter stenosis of the SNA,SNA originating at a diseased right coronary artery(RCA),and larger RCA/SNA diameter ratio were independent predictors of SNO.Bradycardia occurred in SNO,but only one temporary pacemaker was implanted.SNO and the consequent bradycardia were not rare during PCI for severe RCA in current practice,yet they led to a benign clinical course with few temporary pacemakers.

关键词： occlusion coronary stenosis

A new sequential two-stent strategy for treating true distal left main trifurcation lesion

在线全文

学校读者我要写书评

暂无评论

Journal of geriatric Cardiology 2021年第6期18卷 487-491页

作者： Yu-Xiang DAI Chen-Guang LI Jia HUANG Ren-De XU Shu-Fu CHANG Hao LU Dao-Yuan REN Lei ge Ju-Ying QIAN Feng ZHANG jun-bo ge Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular DiseasesShanghaiChina

The incidence of significant left main(LM)coronary artery stenosis identified by coronary angiography was 5%−17.5%in various clinical presentations;about 80%of stenosis involved the LM bifurcation(LMB).[1]Although per-cutaneous coronary intervention(PCI)is an appro-priate alternative to coronary artery bypass graft in LM disease with low-to-intermediate anatomical complexity,[2]PCI for LMB lesions remains the most technically challenging for interventional cardiolo-gists with higher rates of acute periprocedural com-plications and higher risk of long-term major ad-verse cardiac events in the era of drug-eluting stent(DES).

关键词： stenosis acute bypass