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Six-month clinical outcomes of Firebird 2TM sirolimus-eluting stent implantation in real-world patients with coronary artery diseases

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Chinese Medical Journal 2011年第6期124卷 831-835页

作者： GE jun-bo zhang feng QIAN Ju-ying GE Lei LIU Xue-bo ZHOU jun Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital Fudan University Shanghai 200032 China

Background The Firebird 2TM sirolimus-eluting stent （Firebird 2 stent） is a second-generation sirolimus-eluting stent which has a cobalt-chromium alloy stent platform, a brand new bracket structure, and two layers of styrene-butylenes-styrene polymer coatings with better biocompatibility. The Firebird 2TM cObalt-Chromium alloy sirolimus-elUting Stent registry （FOCUS registry） aimed to evaluate the safety and efficacy of the Firebird 2 stent in patients with coronary artery disease in daily *** The FOCUS registry is a prospective, non-randomized, international multi-center, single-arm clinical *** March 2009 and February 2010, 5084 patients receiving at least 1 Firebird 2 stent during daily clinical practice at 83 medical centers were *** Of the 5084 patients enrolled in the registry, 5077 and 5058 were respectively available for 30 days and 6 months follow-up. The 30-day rate of major adverse cardiac events （MACE） was 1.20%, including 13 cardiac deaths, 46 non-fatal myocardial infarction （MI）, and 6 target vessel revascularization （TVR）. At 6 months follow-up, the rate of MACE was 1.80%. There were 32 cardiac deaths, 48 non-fatal MI, and 15 TVR. According to the Academic Research Consortium definition, definite/probable stent thrombosis （ST） occurred in 0.43% （22/5058） of patients, including 8 cases of acute ST, 11 subacute ST, and 3 late *** The Firebird 2 stent showed the promising efficacy and safety at 30 days and 6 months in a real-world population of patients with coronary artery diseases.

关键词： sirolimus-eluting stent percutaneous coronary intervention coronary artery disease cobalt-chromium alloy

Rho signaling inhibitor,Y-27632,inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model

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Chinese Medical Journal 2007年第24期120卷 2304-2307页

作者： XUE feng zhang Jian-jun QIU feng zhang Ming CHEN Xiao-song LI Qi-gen HAN Long-zhi XI Zhi-feng XIA Qiang Organ Transplantation Center Renji Hospital Shanghai Jiao TongUniversity School of Medicine Shanghai 200127 China

Hepatocellular carcinoma(HCC)is among the mostcommon tumors *** extensiveexploration of novel therapies,the prognosis of HCCpatients with intrahepatic metastasis is still poor,and notreatment is effective against ***,... 详细信息

关键词： ROCK inhibitor hepatocellular carcinoma metastasis apoptosis invasiveness

Wire trapping technique combined with retrograde approach for recanalization of chronic total occlusion

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Chinese Medical Journal 2008年第17期121卷 1753-1756页

作者： GE jun-bo zhang feng GE Lei QIAN Ju-ying WANG Hao Department of Cardiology Zhongshan Hospital Fudan University Shanghai Institute of Cardiovascular Diseases Shanghai 200032 China

Coronary chronic total occlusion （CTO）, defined as a ,total occlusion of duration 〉3 months, remains a technical challenge for the interventional cardiologists. The major limitation in percutaneous coronary intervention （PCI） of CTO is the inability to penetrate and cross the occlusion with a guidewire. It was reported that the immediate angiographic success rate varied from 50% to 70% using the standard antegrade techniques.1 To improve this suboptimal success rate, the authors firstly introduced retrograde approach through the collateral channels as a novel technique and successfully recanalized a left main CTO using this technique when demonstrating the live cases in Transcatheter Cardiovascular Therapeutics （TCT） 2005. Recently, modified techniques based on the retrograde approach have demonstrated that this approach could provide a high success rate with PCI.3-5 In the present report, we described a new method, wire trapping technique combined with retrograde approach, which was applied successfully in three patients with CTO.

关键词： chronic total occlusion retrograde approach wire trapping coronary angioplasty

Living donor liver transplantation in 43 children with biliary atresia: a single-center experience from the mainland of China

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Hepatobiliary & Pancreatic Diseases International 2012年第3期11卷 250-255页

作者： Jian-jun Zhu, Qiang Xia, Jian-jun zhang, feng Xue, Xiao-Song Chen, Qi-Gen Li and Ning XuAuthor Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China Department of Liver Surgery Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai 200127 China

BACKGROUND: There is no large-cohort report on living donor liver transplantation (LDLT) for biliary atresia (BA) patients from the mainland of China. This single-center study describes our initial experience with 43 LDLTs for BA patients aged two years or younger. METHODS: In this study, the eligibility criteria were BA as the primary diagnosis and two years of age or younger. From October 2006 to December 2010, the clinical data of 43 LDLTs, including pre-operative evaluations, surgical techniques, postoperative complications and outcomes of donors and recipients, were retrospectively analyzed. RESULTS: Donor graft type was the left lateral segment with compatible ABO blood groups. Forty-three recipients were selected in this study. The median patient age at operation was 9 months (range 6-24), and the median body weight was 8 kg (range 5.7-12.5). Fourteen (32.6%) recipients received Kasai operations before liver transplantation. The overall one- and two-year cumulative survival rates for grafts and recipients were 81%, 81% and 76%, 76%, respectively. No donor mortality was encountered, with a minimal morbidity and no long- term sequelae. Nine out of 43 recipients died. Postoperative complications of recipients were biliary leakage and refluxing cholangitis (11/43, 25.6%), hepatic artery thrombosis (4, 9.3%), pulmonary infections (4, 9.3%), portal vein thrombosis (3, 7.0%), wound disruption (3, 7.0%), acute rejection (3, 7.0%), cytomegalovirus infection (2, 4.7%), and intra-abdominal bleeding (1, 2.3%).CONCLUSION: Despite the relatively low survival rates due to lack of experience initially, LDLT still provides encouraging outcomes for pediatric recipients with BA, even small children under two years old.

关键词： living donor liver transplantation biliary atresia children

Application value of tongue coating microflora in integration of traditional Chinese medicine and modern medicine

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TMR Theory and Hypothesis 2019年第4期2卷 229-240页

作者： Juan Wu jun Qian Li-Yun Shi Zhen Zhan jun-feng zhang School of Medicine&Holistic Integrative Medicine Nanjing University of Chinese MedicineNanjingChina School of Chinese Medicine&Integration of traditional Chinese and Western Medicine Nanjing University of Chinese MedicineNanjingChina

Observation of tongue coating is the characteristic content of traditional Chinese medicine syndrome differentiation and treatment. The microflora is the important component of tongue coating besides the desquamated epithelial cells. Tongue coating microflora might be an important linkage between the modern medical research and the classic traditional Chinese medicine theory. Therefore, the present paper summarised the application value of tongue coating microflora in health and disease to enrich the scienti fic connotation of traditional Chinese medicine tongue diagnosis and promote the development of integration of traditional Chinese medicine and modern medicine.

关键词： Tongue coating Microflora Integration of traditional and western medicine

Effect of Jianpi-yangwei decoction on gut fungi in the patients with gastric cancer undergoing chemotherapy

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Traditional Medicine Research 2021年第2期6卷 29-43页

作者： Chun-Jie Xiang Shuo Xu Juan Wu Yu-Heng Peng Rui Shen Wei Dong Rui-Ping Wang Zhen Zhan jun-feng zhang School of Medicine&Holistic Integrative Medicine Nanjing University of Chinese MedicineNanjing 210023China Jiangsu Province Hospital of Chinese Medicine Nanjing 210029China

Background:Our previous study shows that the empirical formula of Chinese medicine Jianpi-yangwei decoction(JYD)can improve the quality of life in patients with gastric cancer undergoing chemotherapy by increasing beneficial gut bacteria and decreasing harmful *** present study aims to investigate the effect of JYD on gut fungi in patients with gastric cancer undergoing ***:A total of 73 patients with gastric cancer undergoing chemotherapy were ***-nine patients in the chemotherapy group were given standard chemotherapy and 44 patients in the observation group were given JYD plus standard chemotherapy.A control group(55 cases)was recruited from the healthy medical *** 3 months of treatment,life-quality score was evaluated and fecal microbiota was tested by high-throughput sequencing based on the 18S rRNA ***:After treatment,life-quality score in the observation group was significantly lower than that in the chemotherapy group(P<0.05).There was no significant difference between the observation and control groups’diversity and richness indices of intestinal *** Chao index for intestinal fungi in the chemotherapy group was significantly lower than that in the observation group(P<0.05).There was a significant difference between the control and chemotherapy groups in the intestinal fungi according to Shannon and Simpson indices(P<0.05).Linear discriminant analysis effect size analysis showed no significant differences among the three groups,but significant difference in intestinal fungi was observed between the observation group and the chemotherapy *** the genus level,the relative abundance of the Aspergillus genus in the observation and control groups was significantly lower(P<0.05),the relative abundance of the Cutaneotrichosporon,Galactomyces,and Ganoderma genus taxa was significantly higher compared with those in the chemotherapy group(P<0.05),and there was no significant difference between the o

关键词： Gastric cancer Chemotherapy Jianpi-yangwei decoction Gut fungi Aspergillus genus Cutaneotrichosporon genus

Tectonic evolution of the Huangling dome and its control effect on shale gas preservation in the north margin of the Yangtze Block, South China

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China Geology 2020年第1期3卷 28-37页

作者： jun-feng zhang Gang-yi Zhai Da-ming Wang Shu-jing Bao Ke Chen Hao-han Li Teng Song Peng Wang Zhi Zhou Oil and Gas Survey China Geology SurveyMinistry of Natural ResourcesBeijing 100083China

Significant breakthroughs of shale gas exploration have been made in Lower Cambrian and Sinian shale in the north margin of the Yangtze Block,South *** drill wells with industrial gas flow located in the southern margin of the Huangling *** on the geological survey,2D seismic,geochronological and drill wells data,the tectonic evolution history of Huangling dome was studied,and its control effect on the preservation condition of shale gas was *** result shows that the Huangling dome might undergo four tectonic stages:(1)About 800 Ma,granite intrusion in the Huangling dome basement,primarily of granites replaced metamorphism rocks;(2)800-200 Ma,no significant tectonic movement with slowly buried history;(3)From 200 Ma,multi-phase uplift and the sedimentary rocks was eroded in the core of the Huangling *** gas in the Cambrian and Sinian strata was well preserved in the margin of the Huangling dome as the following reasons:(1)The Sinian shale was buried about 7.8 km indepth during Middle Jurassic,source rocks have a suitable thermal maturity for shale gas;(2)The rigid basement of the Huangling dome was mainly composed by homogeneity granite,without intensive *** the main challenges of the widely distributed Lower Cambrian and Sinian shale are highmaturity and intensive deformation,a geological unit with a dome probably is a favorable zone for the old age shale ***,it indicates that the adjacent zone of the Xuefengshan,Shennongjia and Hannan are the geological units with a dome and probably have potentials for the exploration of shale in the Lower Cambrian and Sinian.

关键词： Shale gas Degree of thermal evolution Huangling dome Tectonic evolution Preservation conditions Lower Cambrian and Sinian South China

Research of Dynamic Material Handling in an Automobile General Assembly Line Based on Real-time Information

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International Journal of Plant Engineering and Management 2012年第1期17卷 34-43页

作者： WANG Nan LI Shi-qi WANG jun-feng zhang Zhen-li School of Mechanical Science and Engineering Huazhong University of Science and Technology Wuhan 430074 P. R. China

The status of material delivery of an automobile general assembly line is analyzed, and the technique to achieve the real-time tracking of assembly status information is proposed based on RFID（ Radio Frequency Identification）. Thus the consumption of line-side buffer is obtained dynamically, then the type and quantity of needed material are fed back to the subsystem of material handling; the algorithm for determining the best time departure time of delivery driver based on minimizing of total time penalty function is proposed. This approach makes the material amount of a single delivery trip maximized and improves the efficiency of delivery drivers significantly in the case of does not affect the assembly line normal throughput. Additionally, although this dynamic material handling method is developed for the automobile assembly plant, it should be pointed out that this method is also applicable to other mixed model assembly plants such as electronics, semiconductor and aerospace industry.

关键词： automobile general assembly line material handling best departure time

Structural and microwave absorption properties of CoFe_(2)O_(4)/residual carbon composites

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 221-232页

作者： Yuanchun zhang Shengtao Gao Xingzhao zhang Dacheng Ma Chuanlei Zhu jun He Joint National-Local Engineering Research Centre for Safe and Precise Coal Mining Anhui University of Science and TechnologyHuainan 232001China School of Chemical and Blasting Engineering Anhui University of Science and TechnologyHuainan 232001China

Electromagnetic interference,which necessitates the rapid advancement of substances with exceptional capabilities for bsorbing electromagnetic waves,is of urgent concern in contemporary *** this work,CoFe_(2)O_(4)/residual carbon from coal gasification fine slag(CFO/RC)composites were created using a novel hydrothermal *** mechanisms for microwave absorption,including conductive loss,natural resonance,interfacial dipole polarization,and magnetic flux loss,are involved in these ***,compared with pure residual carbon materials,this composite offers superior capabilities in microwave *** 7.76GHz,the CFO/RC-2 composite achieves an impressive minimum reflection loss(RL_(min))of-43.99 dB with a thickness of 2.44 ***,CFO/RC-3 demonstrates an effective absorption bandwidth(EAB)of up to 4.16 GHz,accompanied by a thickness of *** study revealed the remarkable capability of the composite to diminish electromagnetic waves,providing a new generation method for microwave absorbing materials of superior quality.

关键词： coal gasification slag residual carbon hydrothermal method microwave absorption CoFe_(2)O_(4)