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Analysis and prevention of factors predisposing to infections associated with severe acute pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2003年第2期2卷 619-623页

作者： Bei Sun Ha-Li Li Yue Gao jun Xu Hong-Chi Jiang the department of general surgery, first clinical hospital, harbin medical university, harbin 150001, china department of general surgery First Clinical Hospital Harbin Medical University Harbin 150001 China. sunbei70@***

OBJECTIVE: To analyze factors predisposing to the infections associated with severe acute pancreatitis (SAP) and work out ways for their prevention. METHODS: 208 patients with SAP treated at our hospital from January 1986 to December 2001 were retrospectively analyzed. RESULTS: Statistical difference in the incidence of the infections was found between the following pairs: the groups of bloody or non-bloody ascites, paralytic ileus lasting shorter or longer than 5 days, Ranson's scores lower or higher than 5, hematocrit lower or higher than 45%, CT Balthazar scores lower or higher than 7, and between January 1986-june 1992 or July 1992-December 2001 admissions (x^2>7.58, P0.05). CONCLUSIONS: Occurrence of infection in patients with SAP is closely related with bloody ascites, paralytic ileus (≥5 days), Ranson's scores (≥5), hematocrit (≥45%) and CT Balthazar scores (≥7), but not with pathogenesis, serum calium or total parenteral nutrition. Comprehensive prevention of pancreatic infection and individualized therapy may reduce the incidence of infection.

关键词： severe acute pancreatitis infection prevention

Role of individually staged nutritional support in the management of severe acute pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2004年第3期3卷 458-463页

作者： Bei Sun, Yue Gao, jun Xu, Xiao-Lin Zhou, Zun-Qiang Zhou,Chang Liu and Hong-Chi Jiang department of general surgery, first clinical Hospi-tal, harbin medical university, harbin 150001 ,china department of general surgery First Clinical Hospital Harbin Medical University Harbin 150001China. sunbei70@***

BACKGROUND: Severe acute pancreatitis ( SAP) as acommon acute abdomen due to complicated causes is cha-racterized by lots of morbidities, difficult treatment, andhigh mortality. This study was designed to investigate therole of individually staged nutritional support (ISNS) in thetreatment of ***: One hundred patients with SAP admitted toour hospital from January 1997 to October 2002 were ran-domly divided into total parenteral nutrition group (TPNgroup, 50 patients) and individually staged nutrition group(individualized group, 50 patients), between which thetherapeutic outcome and the incidence of complicationswere carefully ***: Compared with the TPN group, the individuali-zed group had less complications (62 vs 94 patients) inclu-ding incubation related complications (2% vs 16%), super-infections (8% vs 30%), hepatic functional insufficiency(4% vs 24%) and intra-peritoneal infections (4% vs 12%),in addition to a sooner restoring of oral nutrition (18.5 vs24.8 days, Phospital stay (24.5 vs 30.2days) and a lower hospital cost (4.1 vs 5.8 10 000 yuan, Phospital stayand lightened financial burden.

关键词： severe acute pancreatitis enteral nutrition parenteral nutrition

Radiofrequence ablation of liver cancers

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World Journal of Gastroenterology 2002年第3期8卷 393-399页

作者： Lian-Xin Liu Hong-Chi Jiang Da-xun Piao,department of surgery,the first clinical College,harbin medical university,harbin 150001,Heilongjiang Province,china department of surgery the First Clinical College Harbin Medical University No.23 Youzheng Street Nangang District Harbin 150001 Heilongjiang Province China. scott_lxliu@***

Primary and secondary malignant liver cancer are some of most common malignant tumors in the world. Chemotherapy and radiotherapy are not very effective against them. Surgical resection has been considered the only potentially curtive option, but the majority of patients are not candidates for resection because of tumor size, location near major intrahepatic blood vessels and bile ducts, precluding a margin-negative resection, cirrhotic, hepatitis virus infection or multifocial. Radiofrequence ablation (RFA), which is a new evolving effective and minimally invasive technique, can produce coagulative necrosis of malignant tumors. RFA should be used percutaneously, laparascopically, or during the open laparotomy under the guidance of ultrasound, CT scan and MRI. RFA has lots of advantages superior to other local therapies including lower complications, reduced costs and hospital stays, and the possibility of repeated treatment. In general, RFA is a safe, effective treatment for unresectable malignant liver tumors less than 7.0 cm in diameter. We review the principle, mechanism, procedures and experience with RFA for treating malignant liver tumors.

关键词： Carcinoma, Hepatocellular Colorectal Neoplasms Humans Liver Neoplasms Radio Waves Research Support, Non-U.S. Gov't

clinical application of serial operations with preserving spleen

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World Journal of Gastroenterology 2001年第6期7卷 876-879页

作者： Hong-Chi Jiang~1 Bei Sun~1 Hai-Quan Qiao~1 jun Xu~1 Da-xun Piao~1 Hang Yin~2 1 department of general surgery,first clinical hospital,harbin medical university,harbin 150001,china2 department of general surgery,Heilongjiang Provincial hospital,harbin 150001,china department of general surgery First Clinical Hospital Harbin Medical University Harbin 150001 China.

AIM: To evaluate the clinical application of serial operations with preservation of spleen. METHODS: Serial operations with preserving spleen were performed on 211 cases in our hospital from 1980 to 2000. The patient's age ranged from 13 to 56 years, averaging 38 years. Diseases included splenic injury in 171 cases, portal hypertension in 9 cases, splenic cyst in 10 cases, and the lesion of pancreatic body and tail in 21 cases. RESULTS: All the cases were cured, and 129 patients were followed up from 3 months to 3 years with the leukocyte phagocytosis test, detection of immunoglubin, CT,(99m)Tc scanning and ultrasonography. The results were satisfactory. CONCLUSION: The operations with preserving spleen were safe, feasible, and worth of clinical application.

关键词： Adolescent Adult Cysts Humans Hypertension, Portal Middle Aged Pancreatic Diseases Research Support, Non-U.S. Gov't Spleen Splenectomy Splenic Diseases Wounds and Injuries

clinical short-term results of radiofrequency ablation in liver cancers

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World Journal of Gastroenterology 2002年第4期8卷 624-630页

作者： Hong-Chi Jiang Lian-Xin Liu Da-xun Piao jun Xu An-Long Zhu Wei-Hui Zhang Lin-Feng Wu department of surgery,the first clinical College,harbin medical university,harbin 150001,Heilongjiang Province,china Min Zheng department of Ultrasound Diagnosis,the first clinical College,harbin medical university,harbin 150001,Heilongjiang Province,china Shu-Yi Qi Second Inpatient department,the first clinical College,harbin medical university,harbin 150001,Heilongjiang Province,china department of surgery the First Clinical College Harbin Medical University 23 Youzheng Street Nangang District Harbin 150001 Heilongjiang ProvinceChina.

AIM: To study local therapeutic efficacy, side effects, andcomplications of radiofrequency ablation (RFA), whichis emerging as a new method for the treatment ofpatients with hepatocellular carcinoma (HCC) withcirrhosis or chronic hepatitis and metastatic liver ***: Thirty-six patients with primary andsecondary liver cancers (21 with primaryhepatocellular carcinoma, 12 with colorectal cancerliver metastases and 3 with other malignant livermetastases), which were considered not suitable forcurative resection, were include in this study. Theywere treated either with RFA (RITA2000, MountainView, California, USA) percutaneously (n=20)orintraoperatively (n=16).The procedures wereperformed using the ultrasound guidance. The qualityof RFA were based on monitoring of equipments andsubject feeling of the practitioners. Patients treatedwith RFA was followed according to clinical findings,radiographic images, and tumor ***: Thirty-six patients underwent RFA for 48nodules. RFA was used to treat an average 1.3 lesionsper patient, and the median size of treated lesions was2.5 cm (range, 0.5-9 cm). The average hospital staywas 5.6 days overall (2.8 days for percutaneous casesand 7.9 days for open operations). Seven patientsunderwent a second RFA procedure (sequentialablations). Sixteen HCC patients with a high level ofalpha fetoprotein (AFP) and 9 colorectal cancer livermetastases patients with a high level of serumcarcinoembryonic antigen (CEA) have a great reductionbenefited from RFA. Four (11.1 %) patients hadcomplications: one skin burn; one postoperativehemorrhage; one cholecystitis and one hepatic abscessassociated with percutaneous ablations of a largelesion. There were 4 deaths: 3 patients died from localand system diseases (1 at 7 month, 1 at 9 month, and 1at 12 month), 1 patients died from cardiovascular shock,but no RFA-related death. At a median follow-up of 10months (range, 1-24 months), 6 patients (16.7 %) hadrecurrences at an RFA site, and 20 p

关键词：射频消融术肺癌近期疗效影像学检查治疗

Factors predisposing to severe acute pancreatitis:evaluation and prevention

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World Journal of Gastroenterology 2003年第5期9卷 1102-1105页

作者： Bei Sun Ha-Li Li Yue Gao jun Xu Hong-Chi Jiang department of general surgery,first clinical hospital,harbin medical university,harbin 150001,china department of general surgery First Clinical Hospital Harbin Medical University Chin

AIM: To analyze factors predisposing to the infections associated with severe acute pancreatitis (SAP) and to work out ways for its ***: Total 208 cases of SAP treated in this hospital from Jan. 1980 to Dec. 2001 were retrospectively ***: Statistical difference in the incidence of the aforementioned infections was found between the following pairs: between the groups of bloody or non-bloody ascites,paralytic ileus lasting shorter or longer than 5 days, Ranson scores lower or higher than 5, hematocrit lower or higher than 45 %, CT Balthazar scores lower or higher than 7 and between 1980.1-1992.6 or 1992.7-2001.12 admissions (χ2＞3.84, P＜0.05), while no statistical difference was established between the groups of biliogenic and nonbiliogenic pancreatitis, serum amylase ＜200 U/L and ≥200U/L, serum calcium ＜2 mmol/L and ≥ 2 mmol/L or groups of total parenteral nutrition shorter or longer than 7 days (χ2＜3.84, P＞0.05).CONCLUSION: Occurrence of infection in patients with SAP is closely related with bloody ascites, paralytic ileus ≥5 days, Ranson scores ≥5, hematocrit ≥45 % and CT Balthazar Scores ≥7, but not with pathogens, serum calcium and total parenteral nutrition (TPN). Comprehensive prevention of pancreatic infection and practice of individualized therapy contribute to reducing the incidence of infection.

关键词：急性胰腺炎早期诊断危险因素感染血性腹水

Pars plana vitrectomy for retinal detachment using perfluoro-n-octane as intraoperative tamponade:a multicenter,randomized,non-inferiority trial

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 82-91页

作者： Xin Shi Wei-jun Wang Ying Fan Hai-Yun Liu Hong Wang Yu-Hui Chen Ao Rong Zhi-Feng Wu xun Xu Kun Liu department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineNational Clinical Research Center for Eye DiseasesShanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghai 200085China Shanghai Jieshi medical Technology Co.Ltd. Shanghai 201201China department of Ophthalmology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China department of Ophthalmology Wuxi No.2 People’s Hospital(Jiangnan University Medical CenterJUMC)Wuxi 214002Jiangsu ProvinceChina

AIM:To evaluate the efficacy and safety of perfluoro-n-octane(PFO)for ophthalmic surgery versus F-Octane as an intraoperative tamponade in pars plana vitrectomy(PPV)in management of retinal ***:This multicenter,prospective,randomized,double-masked,parallel-controlled,non-inferiority trial was conducted in three ophthalmology clinical centers in *** with retinal detachment,who were eligible for PPV were consecutively *** were assigned to PFO for ophthalmic surgery or F-Octane for intraocular tamponade in a 1:1 ***-corrected visual acuity(BCVA),intraocular pressure(IOP)measurement,and dilated fundus examination were performed preoperatively and at 1,7±1,28±3d *** primary outcome was complete retinal reattachment rate at postoperative day *** non-inferiority margin was set at 9.8%.The secondary outcomes included intraoperative retinal reattachment rate,and mean changes in IOP and BCVA from baseline to 1,7±1,28±3d postoperatively,*** analyses were presented for all randomly assigned participates in this ***:Totally 124 eligible patients completed the study between Mar.14,2016 and jun.7,*** of them were randomly assigned to the PFO for ophthalmic surgery group,and 64 were assigned to the F-Octane *** characteristics were comparable between the two *** groups achieved 100%retinal reattachment at postoperative day one(difference 0,95%CI:-6.21%to 5.75%,P=1).The pre-defined noninferiority criterion was *** significant difference was observed in intraoperative retinal reattachment rate(difference 1.77%,P=0.61),mean changes in IOP(difference 0.36,-0.09,2.22 mm Hg at 1,7±1,28±3d postoperatively,with all P>0.05)and BCVA(difference 0.04,-0.02,0.06 logMAR at 1,7±1,28±3d postoperatively,all P>0.05)between the two *** apparent adverse events related to the utilization of PFO were ***:In patients with retinal detachment undergoing PPV,PFO

关键词： perfluoro-n-octane vitreoretinal surgery intraocular tamponade ophthalmic surgery retinal detachment

Chinese Society of clinical Oncology(CSCO) diagnosis and treatment guidelines for malignant lymphoma 2021(English version)

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Chinese Journal of Cancer Research 2021年第3期33卷 289-301页

作者： jun Zhu jun Ma Union for china Lymphoma Investigators of Chinese Society of clinical Oncology Zhixiang Shen Zifen Gao Huiqiang Huang Xiaoqiu Li Yexiong Li Lugui Qiu Weili Zhao Qingyuan Zhang Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of LymphomaPeking University Cancer Hospital&InstituteBeijing 100142China department of Hematology&Oncology Harbin Institute of Hematology&OncologyHarbin 150010China 不详 Peking university Health Science Center Sun Yat-sen university Cancer Center Fudan university Shanghai Cancer Center Cancer hospital Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Hematology and Blood Diseases hospital Chinese Academy of Medical Science and Peking Union Medical College Ruijin hospital affiliated to Shanghai Jiao Tong university School of Medicine harbin medical university Cancer hospital

1. general guidelines2. Diagnosis3. Staging4. Treatment4.1 Diffuse large B-cell lymphoma(DLBCL)4.2 Follicular lymphoma(FL)4.3 Mantle cell lymphoma(MCL)4.4 Marginal zone lymphoma(MZL)4.5 Burkitt lymphoma(BL)4.6 CLL/Small lymphocytic lymphoma(SLL)4.7 Extra-nodal natural killer/T-cell lymphoma(ENKTCL), nasal type4.8 Peripheral T-cell lymphoma(PTCL)4.9 HL4.10 Primary central nervous system lymphoma5. Prognosis Lymphomas are a group of heterogeneous diseases.

关键词： lymphoma diagnosis lymphocytic

红细胞输注新生儿住院期间发生并发症的危险因素分析

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贵州医科大学学报 2024年第5期49卷 722-727页

作者：蔡姣赵珣李君陈茂琼贵州医科大学附属医院新生儿科贵州贵阳550004 贵州医科大学临床医学院贵州贵阳550004 黄冈市中心医院新生儿科湖北黄冈438000

目的分析红细胞输注(RBCT)新生儿住院期间发生并发症的危险因素。方法收集RBCT治疗的306例新生儿临床资料,根据住院期间是否发生并发症分为并发症组和无并发症组,记录两组患儿一般情况(性别,胎龄,出生体质量,单/多胎,Apgar评分)、住院情... 详细信息

目的分析红细胞输注(RBCT)新生儿住院期间发生并发症的危险因素。方法收集RBCT治疗的306例新生儿临床资料,根据住院期间是否发生并发症分为并发症组和无并发症组,记录两组患儿一般情况(性别,胎龄,出生体质量,单/多胎,Apgar评分)、住院情况(住院时间,机械通气时间,胃肠外营养时间)和红细胞输注相关情况(RBCT前Hb值,出生后第1周医源性失血量,首次RBCT日龄,每次RBCT量,累计RBCT量,累计RBCT次数);采用logistic回归分析,观察RBCT治疗新生儿住院期间发生并发症的危险因素。结果RBCT治疗的306例新生儿,住院期间并发症发生率35.29%(108/306);胎龄、出生体质量、性别、机械通气时间、出生后第1周医源性失血量、住院时间、首次RBCT日龄、每次RBCT量、累计RBCT次数及累计RBCT量是RBCT新生儿住院期间发生并发症的相关危险因素,P<0.05;logistic分析显示,机械通气时间及出生后第1周医源性失血量是RBCT新生儿住院期间发生并发症的独立危险因素,P<0.01。结论机械通气时间长及支气管肺发育不良是新生儿住院期间RBCT治疗常见并发症,出生后第1周时的医源性失血量为独立危险因素。

关键词：新生儿贫血红细胞输注并发症危险因素