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Nonlinear Electrical Impedance Tomography Method Using a Complete Electrode Model for the Characterization of Heterogeneous Domains

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Computer Modeling in Engineering & Sciences 2023年第3期134卷 1707-1735页

作者： Jeongwoo Park Bong-Gu jung jun won kang Department of Civil and Environmental Engineering Hongik UniversitySeoul04066Korea

This paper presents an electrical impedance tomography(EIT)method using a partial-differential-equationconstrained optimization *** forward problem in the inversion framework is described by a complete electrodemodel(CEM),which seeks the electric potential within the domain and at surface electrodes considering the contact impedance between *** finite element solution of the electric potential has been validated using a commercial *** inverse medium problem for reconstructing the unknown electrical conductivity profile is formulated as an optimization problem constrained by the *** method seeks the optimal solution of the domain’s electrical conductivity to minimize a Lagrangian functional consisting of a least-squares objective functional and a regularization *** the stationarity of the Lagrangian leads to state,adjoint,and control problems,which constitute the Karush-Kuhn-Tucker(KKT)first-order optimality ***,the electrical conductivity profile of the domain is iteratively updated by solving the KKT conditions in the reduced space of the control *** results show that the relative error of the measured and calculated electric potentials after the inversion is less than 1%,demonstrating the successful reconstruction of heterogeneous electrical conductivity profiles using the proposed EIT *** method thus represents an application framework for nondestructive evaluation of structures and geotechnical site characterization.

关键词： Electrical impedance tomography complete electrode model inverse medium problem Karush-Kuhn-Tucker(KKT)optimality conditions nondestructive evaluation of structures

Recent progress in quasi-two-dimensional and quantum dot perovskite light-emitting diodes harnessing the diverse effects of ligands:A review

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Nano Research 2022年第7期15卷 6449-6465页

作者： Yurim Bae jun Ryu Saemon Yoon Dong-won kang School of Energy Systems Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Smart City Chung-Ang UniversitySeoul 06974Republic of Korea

Halide perovskites have been extensively studied for use as light-emitting diodes(LEDs)in next-generation displays due to their beneficial characteristics,including their high color purity and wide color *** perovskites can be categorized into four representative structures:three-dimensional(3D)bulk,two-dimensional(2D),quasi-two-dimensional(quasi-2D),and quantum dot(QD).Recently,excellent advances in the performance of perovskite LEDs(PeLEDs),especially those with quasi-2D and QD architectures,have been demonstrated with the incorporation of organic chain *** can both modify the structure of PeLEDs,such as forming multi-quantum wells in quasi-2D PeLEDs and essential passivation layers in QD PeLEDs,and also enhance their optical *** appropriate use of ligands in PeLEDs can thus lead to greater luminescence,current efficiency,power efficiency,and external quantum *** this review,the principal roles of ligands in quasi-2D and QD PeLEDs are systematically ***,current limitations and future perspectives are discussed in detail.

关键词： perovskites light emitting diode ligands quasi-two-dimensional(quasi-2D) quantum dot

Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches

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Traditional Medicine Research 2025年第2期10卷 37-54页

作者： Yong-Chang Zeng jun-Hong Wu Dan-Dan Xu kang He Chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-Yu Liang Department of Neurology The First Affiliated Hospital of Shenzhen UniversityShenzhen 518020China Pharmaceutical Department The Affiliated TCM Hospital of Guangzhou Medical UniversityGuangzhou 510000China School of Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China Guangzhou Zeli Medical Technology Co. Ltd.Guangzhou 510700China

Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for ***,the bioactive components and underlying mechanisms have not been *** objective of this study was to identify the active components and potential mechanisms of SMW by integrating pharmacological experimentation,serum pharmacochemistry,network pharmacology and molecular ***:HUA rats modelling by high-fat/high-sugar diet and potassium oxonate/adenine oral administration were used to evaluate the pharmacodynamic effects of ***-Q-Exactive-MS/MS was employed to detect the bioactive components present in SMW-containing *** pharmacology and molecular docking were utilized to elucidate the potential targets and underlying ***:SMW effectively ameliorated HUA rats via the inhibition of uric acid(UA)production,promotion of UA excretion,improvement of lipid and glucose metabolic abnormalities,antioxidant,anti-inflammatory and anti-insulin resistance effects.A total of 73 compounds detected in SMW-containing serum were identified as potential active components,with alkaloids,flavonoids,organic acids,and terpenoids emerging as the primary active *** 203 corresponding targets were obtained as SMW anti-HUA/gout targets,which mainly participated in apoptosis,insulin resistance,TNF,PI3K-Akt,HIF-1,NF-κB,MAPK,IL-17 and TLR signaling *** docking indicated that active compounds(***,phellodendrine,quercetin,formononetin,ferulic acid)had superior binding abilities to the key targets(*** carrier family 22 member 12(URAT1),solute carrier family 22 member 6(OAT1),ATP-binding cassette sub-family G member 2(ABCG2),solute carrier family 2,facilitated glucose transporter member 9(GLUT9),xanthine dehydrogenase/oxidase(XDH),transcription factor p65(RELA),toll-like receptor 4(TLR4),prostaglandin G/H synthase 2(PTGS2),caspase-3(CASP3),insulin(INS)).Conclusion:S

关键词： hyperuricemia network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS

A New Simulation Model for Recoil Analysis of Deep-Water Drilling Risers After Emergency Disconnection

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China Ocean Engineering 2023年第4期37卷 637-644页

作者： WU jun-kang MENG Shuai State Key Laboratory of Ocean Engineering Shanghai Jiao Tong UniversityShanghai 200240China

The recoil response of a deep-water drilling riser following an ED(Emergency Disconnection)scenario is a transient and sensitive *** recoiling displacement of the riser is the resultant of recoil motion and axial ***-ever,it is typically represented by one variable in recoil *** axial deformation is quite small compared with axial motion in the recoil process,it inevitably introduces numerical errors(i.e.,a large number annihilating a small number).Thus,it is hard to perform a quantitative analysis of axial deformation,although a consensus initial deformation is essential for recoil ***,the triggered axial natural modes have never been examined *** this study,the recoil response is decomposed into two parts:recoil motion and axial deformation,and a novel model is developed by Galerkin *** has demonstrated that the initial stretch has a significant effect at the initial stage in *** existing models underestimate the effects of axial *** new model can capture information of triggered natural modes and figure out the modes undergoing dynamic *** study can be beneficial to overpull setting,determination of ED time and anti-recoil control optimization.

关键词： recoil analysis drilling riser emergency disconnection axial deformation Galerkin method

Introduction to the CDEX experiment

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Frontiers of physics 2013年第4期8卷 412-437页

作者： Ke-jun kang Department of Engineering Physics Tsinghua University Beijing 100084

It is believed that weakly interacting massive particles （WIMPs） are candidates for dark matter （DM） in our universe which come from outer space and might interact with the standard model （SM） matter of our detectors on the earth. Many collaborations in the world are carrying out various experiments to directly detect DM particles. China Jinping underground Laboratory （CJPL） is the deepest underground laboratory in the world and provides a very promising environment for DM search. China Dark matter EXperiment （CDEX） is going to directly detect the WIMP flux with high sensitivity in the low WIMP-mass region. Both CJPL and CDEX have achieved a remarkable progress in recent three years. CDEX employs a point-contact germanium （PCGe） semi-conductor detector whose energy threshold is less than 300 eV. In this report we present the measurement results of muon flux, monitoring of radioactivity and radon concentration carried out in CJPL, as well describing the structure and performance of the 1 kg-PCGe detector in CDEX-1 and 10 kg- PCGe detector array in CDEX-10 including the detectors, electronics, shielding and cooling systems. Finally we discuss the physics goals of CDEX-1, CDEX-10 and the future CDEX-1T experiments.

关键词： China Dark matter EXperiment (CDEX) dark matter poit-contact germanium detector China Jinping underground Laboratory (CJPL)

In?uence of Carbon Equivalent Value on the Weld Bead Bending Properties of High-Strength Low-Alloy Steel Plates

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Journal of Materials Science & Technology 2017年第4期33卷 321-329页

作者： Ki Hyuk Kim In jun Moon Ki won Kim Ki Bong kang Byung Gyu Park Kwang Seok Lee R&D Center of Dongkuk Steel Mill Co. Ltd Pohang 790-729 South Korea Korea Institute of Materials Science Implementation Research Division Materials Deformation Department 797 Changwondaero Changwon Gyeongnarn642-831 South Korea

The contribution of chemical compositions in terms of carbon equivalent value（CEV） on impending crack propagation during weld bead bend tests（WBBTs） was studied with five different high-strength lowalloy steel plates that underwent different rolling processes. The test showed that cracks developed at the weld joint, easily passed through the coarse-grain heat-affected zone（CGHAZ）, and finally were arrested within the heat-affected zone（HAZ）. An apparent decrease in the average crack length, which consequently indicated improvement in crack arrestability, was found with decreasing CEV. In addition,the relatively fine microstructure in the HAZ of low-CEV steel plates helped in preventing the crack from further propagation. Special emphasis was placed on the empirical expectation of critical CEV above which WBBT might fail.

关键词： Mechanical characterization Steel Welding Fracture Crack arrestability against bending

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di Man-Cheng Tang Ding-kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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A modified,simple technique for internal limiting membrane free flap transplantation in macular hole surgery:the Peel-PFCL-Peel technique

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International Journal of Ophthalmology(English edition) 2021年第10期14卷 1636-1638页

作者： Hyun Goo kang Jae Yong Han Jae won jun Min Kim Department of Ophthalmology Institute of Vision ResearchGangnam Severance HospitalYonsei University College of Medicine211 EonjuroGangnam-guSeoul 06273Republic of Korea

Dear Editor,We would like to introduce a simple but modified variant perfluorocarbon liquid(PFCL)-assisted technique,namely the"Peel-PFCL-Peel"technique,which overcomes these difficulties while improving manipulation ... 详细信息

关键词： modified limiting overcome

中国西北地区3种10m全球土地覆被产品林草灌专题要素的一致性评价

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西华师范大学学报（自然科学版） 2025年第1期46卷 42-48页

作者：康军梅王君杨龙伟西安市勘察测绘院西安710054 中煤科工集团武汉设计研究院有限公司武汉430064

中国西北地区的土地利用/土地覆被信息对全球气候变化和生态环境保护有重要影响,因此,及时掌握目前公开发布的几种较高分辨率土地覆被产品的空间一致性极其重要。采用FROM-GLC、ESA和ESRI 3种10 m全球土地覆被产品,通过面积比较、逐像... 详细信息

中国西北地区的土地利用/土地覆被信息对全球气候变化和生态环境保护有重要影响,因此,及时掌握目前公开发布的几种较高分辨率土地覆被产品的空间一致性极其重要。采用FROM-GLC、ESA和ESRI 3种10 m全球土地覆被产品,通过面积比较、逐像元空间叠加和基于样本点的绝对精度评价等方法,分析了这3种产品在林草灌专题要素准确性和空间格局上的差异特征。结果表明:(1)FROM-GLC的总体精度最高,为83.74%;其次是ESA,为68.30%;ESRI的总体精度最低,为52.80%。(2)3种产品林草灌空间一致性较低,完全一致区域面积占比为41.67%,主要分布在研究区的东部;完全不一致区域分布较零散,这些区域地表覆被类型较复杂,地表空间异质性较高。(3)3种产品林地类型的空间一致性较高,草地和灌木类型的判别差异较大。总的来说,草地、灌木等植被类型的精度需要进一步提高。

关键词：林地草地灌木空间一致性精度评价中国西北