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Drying of Flowing Liquid Film on Rotating Disk

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Journal of Thermal Science 2010年第3期19卷 234-238页

作者： Mizue MUNEKATA jun nishiyama Akira NOGUCHI Hiroaki KURISHIMA Hiroyuki YOSHIKAWA Hideki OHBA Department of Mechanical System Engineering Kumamoto University2-39-1 KurokamiKumamoto 860-8555Japan Graduate School of Science and Technology Kumamoto University Tokyo Electron Kyushu LTD. 1-1 FukuharaKoshiKumamoto 861-1116Japan Kikuyo Kumamoto 869-1101Japan

Recently,development of high technology has been required for the formation of uniform thin film in manufacturing processes of semiconductor as the precision instruments become more sophisticated.A method called spin coating is often used for spreading photoresist on a wafer surface and drying photoresist *** spin coating process,photoresist is uniformly spread on the wafer surface by centrifugal force caused by rotating ***,it is a serious concern that streaky lines,which are caused by spiral vortices,appear on the wafer surface and prevent the formation of uniform film in the case of high rotating *** the other hand,in the case of low rotating speed,a small hump of the film is formed near the wafer *** main purpose of this study is to make clear the drying characteristics of the flowing liquid film on the rotating *** distribution of the flowing liquid film is captured by an infrared thermal video camera and radial gradient of the film temperature is introduced in order to evaluate the drying characteristic of the flowing film under steady state *** of the flow rate of the liquid film on the film temperature are *** film temperature gradually decreases in the radial direction in all *** low rotating speed,the radial gradient of the film temperature is almost constant *** the other hand,at high rotating speed,the radial gradient of the film temperature takes a certain maximum *** is found that the location of the gradient peak corresponds with the transition region of the air boundary layer,in which spiral vortices swirl,and shifts to the inner side of the disk with an increase of the liquid flow rate.

关键词： Spin coating Drying characteristic Liquid film flow Air boundary layer Spiral vortex

Is Dose Adjustment Based on Several Factors of Body Size Descriptors Effective for Prevention of Thrombocytopenia by Linezolid Therapy in Hemodialysis Patients?

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Pharmacology & Pharmacy 2016年第10期7卷 417-423页

作者： Hideo Kato Mao Hagihara Yuka Yamagishi Yukihiro Hamada jun Hirai Naoya nishiyama Yusuke Koizumi Katsuhiko Matsuura Hiroshige Mikamo Department of Infection Control and Prevention Aichi Medical University School of Medicine Nagakute Japan Department of Pharmacy Aichi Medical University School of Medicine Nagakute Japan

Previous study suggested that low body weight was one of the risk factors of thrombocytopenia induced by linezolid in non-hemodialysis patients. However, there have been little investigations for the linezolid-induced thrombocytopenia in hemodialysis patients. This study was to evaluate the association between several factors of body size descriptors and thrombocytopenia in hemodialysis-patients. No factor of body size descriptors showed significant correlation with linezolid-induced thrombocytopenia (patients with thrombocytopenia vs patients without thrombocytopenia: body weight;60.0 kg vs 55.3 kg, p = 0.82: body mass indices;21.1 kg/m2 vs 21.2 mg/m2, p = 0.44: ideal body weight;61.2 kg vs 59.5 kg, p = 0.21: lean body weight;50.1 kg vs 45.7 kg, p = 0.64: dosage amount;20.0 mg/kg vs 21.7 mg/kg, p = 0.74: body surface area;1.65 m2 vs 1.54 m2, p = 0.43). There were not significant differences in the body size descriptors between linezolid therapy for more than 14 days and for less than 13 days (more than 14 days vs less than 13 days: body weight;53.5 kg vs 56.8 kg, p = 0.75: body mass indices;20.9 kg/m2 vs 21.1 mg/m2, p = 0.47: ideal body weight;60.3 kg vs 59.9 kg, p = 0.17: lean body weight;44.3 kg vs 47.7 kg, p = 0.56: dosage amount;22.4 mg/kg vs 21.1 mg/kg, p = 0.67: body surface area;1.51 m2 vs 1.59 m2, p = 0.37). Our data suggested that dosage adjustment of linezolid based on body weight was not recommended in hemodialysis-patients.

关键词： Linezolid Thrombocytopenia Body Weight

初诊脑胶质瘤患者4′－[甲基－11C]－硫代胸苷摄取与Ki－67免疫组织化学和肿瘤分级的相关性及与11C－蛋氨酸摄取的对比

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中华核医学与分子影像杂志 2017年第1期37卷 60-60页

作者：黄青清兰晓莉上海同济大学附属第十人民医院核医学科武汉华中科技大学同济医学院附属协和医院核医学科

目的新型放射性药物4′-[甲基-11C]硫代胸苷(11C-4DST)是基于DNA嵌入、反映体内细胞增殖的标志物。该研究旨在评估初诊脑胶质瘤患者的11C-4DST摄取与增殖活性和肿瘤分级的相关性, 并与1-[甲基-11C]-蛋氨酸(11C-MET)摄取进行对比。方法... 详细信息

目的新型放射性药物4′-[甲基-11C]硫代胸苷(11C-4DST)是基于DNA嵌入、反映体内细胞增殖的标志物。该研究旨在评估初诊脑胶质瘤患者的11C-4DST摄取与增殖活性和肿瘤分级的相关性, 并与1-[甲基-11C]-蛋氨酸(11C-MET)摄取进行对比。方法回顾分析23例初诊脑胶质瘤患者的11C-4DST和11C-MET PET/CT显像图, 获得肿瘤(T)的最大标准摄取值(SUVmax)和正常对侧半球(N)的平均SUV, 计算肿瘤/正常(T/N)比值。肿瘤代谢体积(MTV)以40%SUVmax作为阈值计算得出。增殖活性通过组织样本测定的Ki-67指数来评估。结果 23例脑胶质瘤患者中, 20例和22例分别行11C-4DST和11C-MET PET/CT显像。线性回归分析表明, 11C-4DST和11C-MET在SUVmax(r=0.54,P<0.008)、T/N比值(r=0.56,P<0.006)和MTV (r=0.60,P<0.003)间存在弱相关性;11C-4DST和Ki-67指数在SUVmax (r=0.46,P<0.03)、T/N比值(r=0.43,P<0.05)和MTV (r=0.68,P<0.001)上呈弱相关;而且11C-MET MTV和Ki-67指数也呈弱相关(r=0.43,P<0.04)。11C-4DST显像中, 胶质瘤Ⅱ级和Ⅳ级的SUVmax (P<0.03)、Ⅱ级和Ⅳ级的MTV(P<0.009), 及Ⅲ级和Ⅳ级的MTV (P<0.02)差异均有统计学意义。11C-MET显像中, Ⅱ级和Ⅳ级的SUVmax (P<0.009)和T/N比值(P<0.02)、Ⅱ级和Ⅳ级的MTV(P<0.03)、Ⅲ级和Ⅳ级的MTV (P<0.02)差异均有统计学意义。结论 11C-4DST PET/CT用于脑胶质瘤显像是可行的, 11C-MET PET/CT亦然。值得注意的是, 在初诊脑胶质瘤11C-4DST显像中, MTV和Ki-67指数之间呈高度相关。

关键词： 11C-4DST 11C-MET PET 脑胶质瘤增殖

^(11)C-methionine (MET) and ^(18)F-fluorothymidine (FLT) PET in patients withnewly diagnosed glioma

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中国神经肿瘤杂志 2008年第2期6卷 148-148页

作者： Hatakeyama T Kawai N nishiyama Y Yamamoto Y Sasakawa Y Ichikawa T Tamiya T Department of Neurological Surgery Kagawa University School of Medicine1750-1Miki-choKita-gunKagawa761-0793Japan

Eur J Nucl Med Mol Imaging. 2008 jun ***: The purpose of this prospective study was to clarify the individual and combined role of L: -methyl-(11)C-methionine-positron emission tomography (MET-PET) and 3' -deoxy-3' -[(18)F]fluorothymidine (FLT)-PET in tumor detection,noninvasive grad-ing, and assessment of the cellular proliferation rate in newly diagnosed histologically verified gliomas of different grades. MATERI-

关键词：蛋氨酸神经胶质瘤患者诊断方法

铸造奥氏体不锈钢中铁素体与奥氏体位向关系及其对声衰减的影响

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物理学报 2018年第23期67卷 233-241页

作者：罗忠兵董慧君马志远邹龙江朱效磊林莉大连理工大学无损检测研究所大连116085

研究了铸造奥氏体不锈钢中铁素体与奥氏体位向关系及其对超声散射衰减的影响.利用电子背散射衍射技术表征了两相的晶体取向及其位向关系,基于真实的铁素体形貌建立了二维声传播各向异性模型并利用时域有限差分法进行了计算,分析了不同... 详细信息

研究了铸造奥氏体不锈钢中铁素体与奥氏体位向关系及其对超声散射衰减的影响.利用电子背散射衍射技术表征了两相的晶体取向及其位向关系,基于真实的铁素体形貌建立了二维声传播各向异性模型并利用时域有限差分法进行了计算,分析了不同位向关系、铁素体形貌特征对声衰减系数的影响规律并进行了实验验证.结果表明:铸造奥氏体不锈钢奥氏体晶粒中散布着形状复杂的铁素体,典型铁素体形貌为条状和岛状;铁素体与奥氏体的位向关系以Kurdjumov-Sachs关系为主,少量满足nishiyama-Wassermann关系.对声传播过程进行计算,发现两相位向关系和铁素体形貌协同作用影响超声波传播,在较高检测频率(15 MHz)下对散射衰减的影响不能忽略.结合"原位"实验对奥氏体柱状晶粒的声衰减影响因素进行了定量分析,发现对于单一铸造奥氏体晶粒,晶粒内部取向不均匀性、奥氏体-铁素体位向关系以及奥氏体晶粒内铁素体形态都是超声散射衰减的主要原因.

关键词：铸造奥氏体不锈钢超声铁素体声衰减

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马氏体相变的取向关系及变体

河北师范大学学报（自然科学版） 2009年第4期33卷 482-484,490页

作者：王瑞军赵素英张礼刚胡金江河北建筑工程学院数理系河北张家口075024 河北工业职业技术学院

在发生马氏体相变时,马氏体和母相之间存在一定的晶体学位向关系,如K-S关系、nishiyama(西山)关系.研究了K-S和nishiyama(西山)这2种取向关系,分别给出了满足这2种关系的24种和12种马氏体变体.

关键词：马氏体相变取向关系变体