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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen fuqing Chen fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen Mali Chen mingjun Chen mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho ming-chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： jun liu Dan-Dan li Wei Dong yu-Qi liu Yang Wu Da-Xuan Tang fu-chun Zhang meng Qiu Qi Hua Jing-yu He jun li Bai Du Ting-Hai Du lin-lin Niu Xue-jun Jiang Bo Cui Jiang-Bin Chen Yang-Gan Wang Hai-Rong Wang Qin yu Jing He Yi-lin Mao xiao-Fang Bin yue Deng yu-Dan Tian Qing-Hua Han Da-Jin liu li-Qin Duan ming-jun Zhao Cui-Ying Zhang Hai-Ying Dai Ze-Hua li Ying xiao You-Zhi Hu xiao-yu Huang Kun Xing Xin Jiang Chao-feng liu Jing An feng-chun li Tao Tao Jin-Fa Jiang Ying Yang Yao-Rong Dong Lei Zhang Guang fu Ying li Shu-Wei Huang li-Ping Dou Lan-jun Sun Ying-Qiang Zhao Jie li yun Xia jun liu Fan liu Wen-Jin He Ying li Jian-Cong Tan Yang lin Ya-Bin Zhou Jian-Fei Yang Guo-Qing Ma Hui-jun Chen He-Ping liu Zong-Wu liu Jian-Xiong liu xiao-Jia luo xiao-hong Bin Ya-Nan yu Hai-Xia Dang Bing li Fei Teng Wang-min Qiao xiao-long Zhu Bing-Wei Chen Qi-Guang Chen chun-Ti Shen Yong-Yan Wang yun-Dai Chen Zhong Wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF220)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF240),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia(2021 Edition)

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Military Medical Research 2022年第5期9卷 515-533页

作者： Xian-Tao Zeng Ying-Hui Jin Tong-Zu liu Fang-ming Chen De-Gang Ding meng fu Xin-Quan Gu Bang-min Han Xing Huang Zhi Hou Wan-li Hu Xin-li Kang Gong-Hui li Jian-Xing li Pei-jun li Chao-Zhao liang Xiu-Heng liu Zhi-yu liu chun-xiao liu Jiu-min liu Guang-Heng luo Yi luo Wei-jun Qin Jian-hong Qiu Jian-Xin Qiu Xue-jun Shang Ben-Kang Shi Fa Sun Guo-Xiang Tian Ye Tian feng Wang feng Wang Yin-Huai Wang yu-Jie Wang Zhi-Ping Wang Zhong Wang Qiang Wei min-Hui xiao Wan-Hai Xu Fa-Xian Yi Chao-Yang Zhu Qian-yuan Zhuang li-Qun Zhou xiao-feng Zou Nian-Zeng Xing Da-lin He Xing-Huan Wang 无 Department of Urology Institute of UrologyZhongnan Hospital of Wuhan UniversityWuhan430071China Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Urology Tianjin Third Central Hospital Affiliated To Nankai UniversityTianjin300170China Department of Urology Henan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou450003China Department of Urology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China Department of Urology China-Japan Union Hospital of Jilin UniversityChangchun130033China Department of Urology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Urology Qinghai University Affiliated HospitalXi’ning810012China Department of Urology People’s Hospital of Hainan ProvinceHainan Affiliated Hospital of Hainan Medical University HaikouHaikou570311China Department of Urology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou310016China Department of Urology General Hospital of Ningxia Medical UniversityYinchuan750003China Department of Urology The First Affiliated Hospital of Anhui Medical UniversityHefei230022China Department of Urology Renmin Hospital of Wuhan UniversityWuhan430060China Department of Urology The Second Hospital of Dalian Medical UniversityDalian116023LiaoningChina Department of Urology Zhujiang Hospital of Southern Medical UniversityGuangzhou510282China Department of Urology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou510080China Department of Urology Surgery Guizhou Province People’s HospitalGuiyang550002China Department of Urology Xijing Hospital of Air Force Military Medical UniversityXi’an710032China Department of Urology The 980St Hospital of the PLA Joint Logistics Support Force(Bethune International Peace Hospital of PLA)Shijiazhuang050082China Department of Urology

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different

关键词： Transurethral plasmakinetic resection of prostate Benign prostatic hyperplasia Recommendation Treatment Guideline

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu yue Huang Guang-Cheng xiao Qing-Cui Bu Jin-lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia Fang-jun lu Xiang Ma lian Tao Wei Zhang li Chen li-ming Song Ti-Pei li yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen yu-Peng Chen Wei Cui Wei-Wei Cui Jing-Kang Deng Yong-Wei Dong yuan-yuan Du min-Xue fu Guan-Hua Gao He Gao min Gao ming-yu Ge yu-Dong Gu Ju Guan Cheng-Cheng Guo Da-Wei Han Jia Huo lu-Hua Jiang Wei-chun Jiang Jing Jin Yong-Jie Jin ling-Da Kong Bing li Cheng-Kui li Gang li Mao-Shun li Wei li Xian li xiao-Bo li Xu-Fang li Yang-Guo li Zheng-Wei li xiao-Hua liang Jing-yuan liao Bai-sheng liu Guo-Qing liu hong-Wei liu xiao-Jing liu Yi-Nong liu Bo lu Xue-feng lu Qi luo Tao luo Bin meng Yi Nang Jian-Yin nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song liang Sun Ying Tan You-li Tuo Chen Wang Guo-feng Wang Juan Wang ling-jun Wang Weng-Shuai Wang yu-Sa Wang Xiang-Yang Wen Bai-Yang Wu Bo-Bing Wu Mei Wu Shuo xiao Shao-lin Xiong He Xu Jia-Wei Yang sheng Yang Yan-Ji Yang Yi-jung Yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang hong-Mei Zhang Juan Zhang Tong Zhang Wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang yuan-Hang Zhang yue Zhang Zhao Zhang Zhi Zhang Zi-liang Zhang Hai-sheng Zhao xiao-Fan Zhao Shi-Jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-feng Zhou yu-Xuan Zhu Ren-lin Zhuang yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

经穴效应特异性在穴位注射多巴酚丁胺增效作用中的体现

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针刺研究 2010年第3期35卷 188-192页

作者：崔晶晶高俊虹付卫星王玉敏马淑骅张萌崔海峰喻晓春中国中医科学院医学实验中心北京100700 中国中医科学院针灸研究所北京100700 辽宁医学院药理教研室锦州121001

目的:探讨药物穴位注射是否体现穴位效应的相对特异性。方法:SD大鼠随机分为正常对照组、电针内关+穴位注射组(EA-PC6+AI组)、电针足三里+穴位注射组(EA-ST36+AI组)和电针常规肌肉注射部位+注射组(EA-IMIS+IMI组),每组8只。电针各组分... 详细信息

目的:探讨药物穴位注射是否体现穴位效应的相对特异性。方法:SD大鼠随机分为正常对照组、电针内关+穴位注射组(EA-PC6+AI组)、电针足三里+穴位注射组(EA-ST36+AI组)和电针常规肌肉注射部位+注射组(EA-IMIS+IMI组),每组8只。电针各组分别电针10min后,再于相应部位注射β1-肾上腺素受体的激动剂盐酸多巴酚丁胺(DH,100μg/kg)。分析比较相应部位电针+注射DH前,电针+注射DH后2、5、15和30min左心室收缩压(LVSP)、心率(HR)和左心室最大上升速率(+dp/dtmax)变化。结果:相应部位电针+注射DH后2min时,以EA-PC6+AI组增加LVSP、HR和+dp/dtmax的药理作用表现最为明显(各组相应指标与同时间点EA-PC6+AI组比较Pmin时,EA-ST36+AI和EA-IMIS+IMI组心功能各项指标均有较大幅度的回落,而EA-PC6+AI组LVSP、HR和+dp/dtmax的回落幅度最低(与同时间点正常对照组比较均P<0.01)。结论:电针"内关"穴加穴位注射确实有作用较强、作用时间窗宽大等优势,体现了其对心脏功能影响的相对特异性。

关键词：内关穴电针穴位注射经穴效应特异性心脏效应

Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： yu Cao Song Chen Yan-Fen Chai xiao-Hui Chen yu-Guo Chen Shao-Wen Cheng Wen-Wei Cheng Bang-Han Ding Yang Deng Jie fu Bang-Jiang Fang Mai-Ying Fan li Gui Ping Gong Wei Guo Shu-Bin Guo liang Huang Ji-yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji hong-Xu Jin Xin-jun Jiang Wang-Xiang Jiang Jia-liang liu xiao-Ran liu Zhi liu Chuan-Zhu Lv feng lu Tan-Shi li Xin li Yong li Shang-lun li Shuang-ming li xiao-Gang li Bao-jun li Pei-Wu li chun-sheng li Zhi-jun li Chang-luo li Xiang-min li Yin-Ping li Zong-jun lu Zu-Xun lu Zhong-Qiu lu Zhi-Qian luo xiao-Xing liao Jian-Bo Lei Tao Ma yu Ma yue-feng Ma Qing-Bian Ma lin-Hao Ma jun-Qi Ma Shi-Nan nie Jie-Miao Ou-Yang Peng Peng Qiao Pei Shu-ming Pan Guo-Zhong Qing li-Jie Qin Wu-Ying Qiao Fei Shao Wei Song Xing-yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian Ying-Ping Tian Jian-Guang Tian Chao-Yang Tong Zi-Ren Tang meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao Wang Xin Wang Peng Wang Zhong Wang Tong Wang Ri-Xing Wang Yi-Xin Wang xiao-Dan Wang ling Wu Wei Wei Hua Xiang feng Xu jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu feng yu Wen Yi li-Shan Yang Shi-Jiao Yan Jin-Jian Yao Shou-chun Yan Xue-Zhong yu Xian-Zhi Ye Xian-liang Yan fu-Bing Zhou Rong-Bin Zhou ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu Hua-Dong Zhu Ji-hong Zhu hong Zhang Mao Zhang Hua Zhang Na Zhang Guo-Qiang Zhang Guo-Xiu Zhang Jin-Song Zhang Wen-Wu Zhang Wen-Zhong Zhang Jian-feng Zhang Yi-min Zhu jun Zeng yuan Zheng Zhi-Jie Zheng Shen Zhao Yan Zhao min Zhao Bin Zhao xiao-Dong Zhao xiao-Jing Zhao hong-Ke Zeng sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

穴位不同组织结构决定和影响经穴-内脏效应特异性的科学基础

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中国针灸 2010年第4期30卷 293-295页

作者：高俊虹王玉敏崔晶晶马淑骅崔海峰付卫星张萌王洪新喻晓春中国中医科学院针灸研究所北京100700 中国中医科学院医学实验中心北京100700 辽宁医学院药理学系

经穴特异性是针灸学的基本理论之一,也是指导针灸临床治疗最重要的依据。但是,穴位特异性科学基础至今仍不明确,严重制约着针灸临床疗效的提高,并影响到针灸学国际国内的学术地位。本文回顾了近年来相关的科学研究,并在此基础上就穴区... 详细信息

经穴特异性是针灸学的基本理论之一,也是指导针灸临床治疗最重要的依据。但是,穴位特异性科学基础至今仍不明确,严重制约着针灸临床疗效的提高,并影响到针灸学国际国内的学术地位。本文回顾了近年来相关的科学研究,并在此基础上就穴区不同组织结构在决定和影响穴位效应特异性中的关键作用及其机制进行了分析探讨,认为由于不同经穴穴区组织结构不同,针刺不同的经穴或同一经穴不同深度的组织结构,将因刺激不同组织内的不同感受器而兴奋不同类别的传入纤维,进而引起不同性质或不同程度的内脏功能变化。

关键词：穴位特异性针灸效应组织结构科学基础

Molecular dissection of the phenylpropanoid-flavonoid-proanthocyanidin compound pathway from Brassica species

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Molecular dissection of the phenylpropanoid-flavonoid-proant...

2017年中国ICU患者营养治疗实施状况横断面调查

重庆市生物化学与分子生物学学术会议

作者： You-Rong Chai,Jia-Na li,jun-lu,Bo Lei,An-He Chen,yu Ni,Bo li,Kai Zhang,Ben-Bo Xu,li-Juan Ma, Juan Du,Di Zhang,Rui Yin,Shu-ling Di,yun-liang Wei,xiao-chun lu,Wen-jun Zhao,hong Leng, Hua-Lei Huang,ling-li Xie,Bei-Bei lin,Yan-Zhen Dong,yu feng,yu-ming Wang,Fan-min meng, Wei-Ran Zhong,Kun lu,Jia-ming Yin,Zhang-lin Tang,Rui Wang,li Chen,Ying liang,Qing-yuan Zhou, Guang-Wei Yang,Guan-Rong li,lie-Zhao liu,Xin-fu Xu,yun-Tao li,Cheng-jun Yang,and Zi-Chao Zhu (Chongqing Rapeseed Technology Research Center Chongqing Key Laboratory of Crop Quality Improvement Key Lab of Biotechnology & Crop Quality Improvement of ministry of Agriculture College of Agronomy and Biotechnology,Southwest University,Chongqing 400716)

Brassica species especially"amphidiploid"*** and its"diploid"parental species *** and B. oleracea are indispensable oilseed,vegetable or ornamental crops *** phenylpropanoid compound pathway produces one of the largest groups of plant secondary metabolites of important biological,agronomic,and even medicinal *** example,flavonols,anthocyanins,

关键词： Brassica napus Brassica oleracea Brassica rapa Comparative genomics Flavonoid Molecular evolution Pathway Phenylpropanoid Proanthocyanidin

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解放军医学杂志 2019年第5期44卷 388-393页

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目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施... 详细信息

目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施和胃肠道耐受情况,以及患者的28 d临床转归情况。结果调查共收集病例1953例,女631例(32.4%),男1306例(66.9%),缺失16例(0.7%);年龄(64.1±19.3)岁(1950例)。患者GCS、SOFA和APACHEⅡ评分分别为(10.76±4.35)分(1749例)、(5.65±3.52)分(1783例)、(17.14±7.31)分(1792例)。28 d临床转归存活1483例(75.9%),死亡312例(16.0%),失访+缺失158例(8.1%)。除身高和体重(P=0.000)外,男性与女性患者在年龄、病情严重程度及28 d临床转归等方面差异均无统计学意义。1953例患者中,胃肠功能评估为正常或轻度损害占73.7%(1440例),中-重度损害占10.8%(210例),衰竭占1.7%(33例),13.2%(258例)的患者未做评估。截至调查日,69.4%(1356例)的患者已启动肠内营养(EN),36.4%(711例)的患者已启动肠外营养(PN)。调查日有营养摄入的患者1720例(88.1%)。1953例患者中明确有恶心、呕吐反流、误吸、腹痛、腹胀、腹泻(大便次数≥3次/d且量≥500 ml/d)等胃肠道不耐受表现的分别占总人数的4.8%(93例)、5.4%(105例)、0.9%(17例)、8.7%(170例)、27.5%(538例)和4.3%(84例)。在1270例使用EN的病例中,明确存在恶心、呕吐反流、误吸、腹痛、腹胀、腹泻等不耐受症状的分别占3.2%(40例)、4.3%(54例)、0.8%(10例)、4.4%(56例)、26.9%(341例)和5.4%(69例)。入ICU后24 h内开始EN治疗的患者占22.4%(437/1953),48 h内开始的占38.6%(754/1953),72 h内开始的占46.6%(911/1953)。患者入ICU后3 d总热卡(EN+PN非蛋白热卡)达标率为12.9%(78/607),7 d总热卡达标率为18.7%(189/1010),14 d总热卡的达标率为23.0%(305/1325)。入ICU后3、7、14 dEN达标率分别为9.9%(60/607)、15.0%(151/1010)和18.6%(246/1325)。结论目前我国ICU内的绝大多数患者均接受了营养治疗,其中EN的使用率明显高于PN;但EN的开始时间和达标情况仍不理想,且实施营养治疗时未能体现个体化差异,营养治疗的细节仍需要提高。

关键词：横断面研究肠内营养重症监护病房胃肠道耐受性营养达标率