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Correlation between gut microbiota and tumor immune microenvironment:A bibliometric and visualized study

World Journal of Clinical Oncology 2025年第2期16卷 110-129页

作者： Zheng-jun hu hui-Rong Zhu Yong-Jie Jin Pan Liu Xiao-Wei Yu Yu-Ren Zhang Department of Oncology Shanghai Jiading District Hospital of Traditional Chinese MedicineShanghai 200000China Department of Oncology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200000China School of Chinese Medicine Anhui University of Traditional Chinese MedicineHefei 230000Anhui ProvinceChina

BACKGROUND In recent years,numerous reports have been published regarding the relationship between the gut microbiota and the tumor immune microenvironment(TIME).However,to date,no systematic study has been conducted on the relationship between gut microbiota and the TIME using bibliometric *** To describe the current global research status on the correlation between gut microbiota and the TIME,and to identify the most influential countries,research institutions,researchers,and research hotspots related to this *** We searched for all literature related to gut microbiota and TIME published from January 1,2014,to May 28,2024,in the Web of Science Core Collection *** then conducted a bibliometric analysis and created visual maps of the published literature on countries,institutions,authors,keywords,references,etc.,using CiteSpace(6.2R6),VOSviewer(1.6.20),and bibliometrics(based on R 4.3.2).RESULTS In total,491 documents were included,with a rapid increase in the number of publications starting in *** country with the highest number of publications was China,followed by the United *** has the highest number of citations in *** a centrality perspective,the United States has the highest influence in this *** institutions with the highest number of publications were Shanghai Jiao Tong University and Zhejiang ***,the institution with the most citations was the United States National Cancer *** authors,Professor Giorgio Trinchieri from the National Institutes of Health has the most local impact in this *** most cited author was Fan *** results of journal publications showed that the top three journals with the highest number of published papers were Frontiers in Immunology,Cancers,and Frontiers in *** three most frequently used keywords were gut microbiota,tumor microenvironment,and *** This study systematically elaborates on the research progress re

关键词： Gut microbiota Tumor immune microenvironment Bibliometric CiteSpace VOSviewer R-bibliometrics

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FINITE ELEMENT APPROXIMATIONS OF SYMMETRIC TENSORS ON SIMPLICIAL GRIDS IN R^n： THE HIGHER ORDER CASE

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Journal of Computational Mathematics 2015年第3期33卷 283-296页

作者： jun hu LMAM School of Mathematical Sciences and Beijing International Center for Mathematical Research Peking University Beijing 100871 P. R. China.

The design of mixed finite element methods in linear elasticity with symmetric stress approximations has been a longstanding open problem until Arnold and Winther designed the first family of mixed finite elements where the discrete stress space is the space of H（div,Ω;S）-Pk＋1 tensors whose divergence is a Pk-1 polynomial on each triangle for k ≥ 2. Such a two dimensional family was extended, by Arnold, Awanou and Winther, to a three dimensional family of mixed elements where the discrete stress space is the space of H（div, Ω; S）-Pk＋2 tensors, whose divergence is a Pk-1 polynomial on each tetrahedron for k ≥ 2. In this paper, we are able to construct, in a unified fashion, mixed finite element methods with symmetric stress approximations on an arbitrary simplex in R^n for any space dimension. On the contrary, the discrete stress space here is the space of H（div,Ω; S）-Pk tensors, and the discrete displacement space here is the space of L^2（Ω; R^n）-Pk＋1 vectors for k ≥ n＋ 1. These finite element spaces are defined with respect to an arbitrary simplicial triangulation of the domain, and can be regarded as extensions to any dimension of those in two and three dimensions by hu and Zhang.

关键词： Mixed finite element Symmetric finite element First order system Simplicial grid Inf-sup condition.

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UNIFORMLY A POSTERIORI ERROR ESTIMATE FOR THE FINITE ELEMENT METHOD TO A MODEL PARAMETER DEPENDENT PROBLEM

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Journal of Computational Mathematics 2008年第5期26卷 716-727页

作者： Yiran Zhang jun hu LMAM and School of Mathematical Sciences Peking University Beijing 100871 China

This paper proposes a reliable and efficient a posteriori error estimator for the finite element methods for the beam problem. It is proved that the error can be bounded by the computable error estimator from above an... 详细信息

关键词： The beam problem A posteriori error estimator Finite element method.

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Global sensitivity analysis based on high-dimensional sparse surrogate construction

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Applied Mathematics and Mechanics(English Edition) 2017年第6期38卷 797-814页

作者： jun hu Shudao ZHANG Institute of Applied Physics and Computational Mathematics

Surrogate models are usually used to perform global sensitivity analysis （GSA） by avoiding a large ensemble of deterministic simulations of the Monte Carlo method to provide a reliable estimate of GSA indices. However, most surrogate models such as polynomial chaos （PC） expansions suffer from the curse of dimensionality due to the high-dimensional input space. Thus, sparse surrogate models have been proposed to alleviate the curse of dimensionality. In this paper, three techniques of sparse reconstruc- tion are used to construct sparse PC expansions that are easily applicable to computing variance-based sensitivity indices （Sobol indices）. These are orthogonal matching pursuit （OMP）, spectral projected gradient for L1 minimization （SPGL1）, and Bayesian compressive sensing with Laplace priors. By computing Sobol indices for several benchmark response models including the Sobol function, the Morris function, and the Sod shock tube problem, effective implementations of high-dimensional sparse surrogate construction are exhibited for GSA.

关键词： global sensitivity analysis (GSA) curse of dimensionality sparse surrogate construction polynomial chaos (PC) compressive sensing

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Finite Time Ruin Probabilities and Large Deviations for Generalized Compound Binomial Risk Models

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Acta Mathematica Sinica,English Series 2005年第5期21卷 1099-1106页

作者： Yi jun hu School of Mathematics and Statistics Wuhan University Wuhan 430072 P. R. China

In this paper, we extend the classical compound binomial risk model to the case where the premium income process is based on a Poisson process, and is no longer a linear function. For this more realistic risk model, Lundberg type limiting results for the finite time ruin probabilities are derived. Asymptotic behavior of the tail probabilities of the claim surplus process is also investigated.

关键词： Ruin probability (Generalized) compound binomial risk model Large deviations

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Distributed Resilient Fusion Filtering for Nonlinear Systems with Random Sensor Delays:Optimized Algorithm Design and Boundedness Analysis

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Journal of Systems Science & Complexity 2023年第4期36卷 1423-1442页

作者： hu jun hu Zhibin DONG Hongli LIU Hongjian School of Automation Harbin University of Science and TechnologyHarbin 150080China Department of Mathematics Harbin University of Science and TechnologyHarbin 150080China Heilongjiang Provincial Key Laboratory of Optimization Control and Intelligent Analysis for Complex Systems Harbin University of Science and TechnologyHarbin 150080China Heilongjiang Provincial Key Laboratory of Networking and Intelligent Control Northeast Petroleum UniversityDaqing 163318China School of Mathematics-Physics and Finance Anhui Polytechnic UniversityWuhu 241000China

This paper is concerned with the distributed resilient fusion filtering(DRFF)problem for a class of time-varying multi-sensor nonlinear stochastic systems(MNSSs)with random sensor delays(RSDs).The phenomenon of the RSDs is modeled by a set of random variables with certain statistical *** addition,the nonlinear function is handled via Taylor expansion in order to deal with the nonlinear fusion filtering *** aim of the addressed issue is to propose a DRFF scheme for MNSSs such that,for both RSDs and estimator gain perturbations,certain upper bounds of estimation error covariance(EEC)are given and locally minimized at every sample *** the light of the obtained local filters,a new DRFF algorithm is developed via the matrix-weighted fusion ***,a sufficient condition is presented,which can guarantee that the local upper bound of the EEC is ***,a numerical example is provided,which can show the usefulness of the developed DRFF approach.

关键词： Distributed resilient fusion filtering matrix-weighted fusion nonlinear time-varying systems random sensor delays

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Schubert Class and Cyclotomic NilHecke Algebras

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Algebra Colloquium 2021年第3期28卷 379-398页

作者： Kai Zhou jun hu School of Mathematical Sciences Zhejiang UniversityHangzhou 310027China School of Mathematics and Statistics Beijing Institute of Technology Beijing 100081China

Let l and n be positive integers such that l≥n,and let Gn,l be the Grassmannian which consists of the set of n-dimensionsil subspaces of C^(l),There is a Z-graded algebra isomorphism between the cohomology H*(Gn,l,Z)of Gn,l and a natural Z-form B of the Z-graded basic algebra of the type A cyclotomic nilHecke algebraH^(0)l,n=.We show that the isomorphism can be chosen such that the image of each(geometrically defined)Schubert class(a1,...,an)coincides with the basis element bλconstructed by hu and Liang by purely algebraic method,where 0≤q1≤q2≤…≤an≤l-n with ai∈Z for each i,andλis the l-€-multipartition of n associated to(l+1-(an+n),l+1-(an-1+n-),...,l+1-(a1+1)).A similar correspondence between the Schubert class basis of the cohomology of the Grassmanni-an Gl-n,l and the bλ's basis(λis anl-multipartition of n with each component being either(1)or empty)of the natural Z-form B of the Z-graded basic algebra of H^(0)_(l,n)is also *** an application,we obtain a second version of the Giambelli formula for Schubert classes.

关键词： cyclotomic nilHecke algebras Grassmannians Schur polynomials

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Design of a Sector Cascade Applied in the Middle Stage of a Compressor Test Rig

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Journal of Thermal Science 2022年第2期31卷 485-494页

作者： WANG Jiayu hu jun JIANG Chao LI jun College of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Jiangsu Province Key Laboratory of Aerospace Power System Nanjing 210016China

A compressor test platform was designed in the purpose of easy assembly and cost-saving *** design concepts were firstly used on the test platform and iterative revisions were conducted to verify the effects,which decrease the risk of applying to the full annulus *** platform was a sector cascade that can be inserted into an otherwise full stator annulus,with a set of exchangeable endwall casing and blades manufactured by 3-D *** platform can create an operating condition which is closer to engine-realistic flow conditions than traditional cascade *** flow field of the prototype stator was tested in detail at the operating point and showed some flow defects in the tip region,and then three design plans were conducted to experimentally investigate which design concept could improve the blade tip *** concept of casing endwall profiling was the most effective one which markedly depressed the separation of the tip region and decreased the total pressure loss *** test results show that the design of the test platform was successful and promising,which could be used to conduct more researches on the flow mechanism of the middle stage.

关键词： sector cascade compressor test platform 3-D printing

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AN ERROR ANALYSIS METHOD SPP-BEAM AND A CONSTRUCTION GUIDELINE OF NONCONFORMING FINITE ELEMENTS FOR FOURTH ORDER ELLIPTIC PROBLEMS

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Journal of Computational Mathematics 2020年第1期38卷 195-222页

作者： jun hu Shangyou Zhang LMAM and School of Mathematical Sciences Peking UniversityBeijing 100871China Department of Mathematical Sciences University of DelawareNewarkDE 19716USA

Under two hypotheses of nonconforming finite elements of fourth order elliptic problems,we present a side-patchwise projection based error analysis method(SPP-BEAM for short).Such a method is able to avoid both the regularity condition of exact solutions in the classical error analysis method and the complicated bubble function technique in the recent medius error analysis *** addition,it is universal enough to admit ***,we propose a sufficient condition for these hypotheses by imposing a set of in some sense necessary degrees of freedom of the shape function *** an application,we use the theory to design a P3 second order triangular H2 non-conforming element by enriching two P4 bubble functions and,another P4 second order triangular H2 nonconforming finite element,and a P3 second order tetrahedral H2 non-conforming element by enriching eight P4 bubble functions,adding some more degrees of freedom.

关键词： Nonconforming finite element A priori error analysis Biharmonic equation

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CONSTRAINED QUADRILATERAL NONCONFORMING ROTATED Q1 ELEMENT

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Journal of Computational Mathematics 2005年第6期23卷 561-586页

作者： jun hu Zhong-ci Shi LSEC ICMSEC Academy of Mathematics and System Sciences Chinese Academy of Sciences Beijing 100080 China

In this paper, we define a new nonconforming quadrilateral finite element based on the nonconforming rotated Q1 element by enforcing a constraint on each element, which has only three degrees of freedom. We investigate the consistency, approximation, superclose property, discrete Green＇s function and superconvergence of this element. Moreover, we propose a new postprocessing technique and apply it to this element. It is proved that the postprocessed discrete solution is superconvergent under a mild assumption on the mesh.

关键词： Constrained Nonconforming Rotated Q1 element Superconvergence Postprocess

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