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New stability conditions of CPSs with multiple transportation channels under DoS attacks

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Science China(Information Sciences) 2022年第11期65卷 301-302页

作者： jumei wei Xueyan YAN Xunlin ZHU Mingliang XU Rui MA Haiping DU School of Mathematics and Statistics Zhengzhou University Center for Interdisciplinary Information Science Research Zhengzhou University School of Electrical Computer and Telecommunications Engineering University of Wollongong

Dear editor,Cyber-physical systems(CPSs) are widely studied owing to their cyclopedic practical value in some fields. In an unreliable network environment, transmission channels may be subject to denial-of-service(Do ...

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广义多自主体系统的一致性

郑州大学学报（理学版） 2019年第1期51卷 29-33页

作者：魏菊梅支慧敏郑州大学数学与统计学院河南郑州450001

考虑了一类切换拓扑下的广义多自主体系统,利用代数图论和广义系统理论,分两种情形(无领导者和领导者跟随)来研究其一致性.通过研究慢子系统的一致性从而得到了广义多自主体系统的两个一致性.

关键词：广义多自主体系统切换拓扑一致性

An Extension of LaSalle’s Invariance Principle for Discontinuous systems

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An Extension of LaSalle’s Invariance Principle for Disconti...

第24届中国控制与决策会议

作者： jumei wei 1 , Xiaowu Mu 1 , Rui Ma 1 1. Department of Mathematics, Zhengzhou University, HeNan, 450001, China

In this paper, discontinuous righthand sides dynamical systems are considered. An extension of LaSalle invariance principle is presented by using locally Lipschitz continuous and nonpathological Lyapunnov functions. This result is used to locate chaotic attractors of studied systems, and less restrictive conditions are required. Numerical example has been given to illustrate the correctness of the theorem.

关键词： Nonpathological Discontinuous Righthand Sides Invariance Principle

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县级站在验收监测中存在的问题

环境与发展 2012年第6期24卷 188-189页

作者：魏菊梅湖北省孝感市孝南区环境监测站湖北432100

结合多年在县级环境监测站工作的实践,提出建设项目竣工环境保护验收监测程序中普遍存在的问题,以期提高县级监测站验收监测的监测能力。

关键词：县级环境监测站建设项目竣工验收监测问题

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县级站在环境监测验收工作中应注意的问题

环境与发展 2013年第2期25卷 147-149页

作者：魏菊梅湖北省孝感市孝南区环境监测站湖北432100

结合多年在县级环境监测站工作的实践,提出建设项目竣工环境保护验收监测程序中普遍存在的问题,以期提高县级监测站验收监测的监测能力。

关键词：县级环境监测站建设项目竣工验收监测问题

盐酸左西替利嗪对人毛乳头细胞生长影响的初步研究

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中华皮肤科杂志 2019年第6期52卷 389-394页

作者：韦菊梅温斯健包家娟庄晓晟林有坤广西医科大学第一附属医院皮肤科南宁530022

目的初步探讨不同浓度盐酸左西替利嗪对体外培养人毛乳头细胞(hDPC)生长的影响及机制。方法将hDPC在含1,10、100、1 000 、10 000 μg/L盐酸左西替利嗪的DMEM培养液中培养48 h,免疫荧光染色观察细胞的生长情况,M1T法检测细胞增殖活力,... 详细信息

目的初步探讨不同浓度盐酸左西替利嗪对体外培养人毛乳头细胞(hDPC)生长的影响及机制。方法将hDPC在含1,10、100、1 000 、10 000 μg/L盐酸左西替利嗪的DMEM培养液中培养48 h,免疫荧光染色观察细胞的生长情况,M1T法检测细胞增殖活力,实时荧光定量PCR法检测环氧化酶2(COX-2)、前列腺素D2合酶(PTGDS)、前列腺素E2(PGE2)、前列腺素F2α(PGF2α)、G蛋白偶联受体44(GPR44)、蛋白激酶B(AKT)、糖原合成酶激酶30(GSK30)的mRNA表达水平;Western印迹法检测PTGDS蛋白水平。hDPC在含以上浓度盐酸左西替利嗪的DMEM培养液中培养24 h,酶联免疫吸附试验检测培养上清液中前列腺素D2(PGD2)和PGD2受体(PGD2R)的水平。以不加药物同等条件培养的hDPC为对照组。采用SPSS17.0软件进行单因素方差分析,组间两两比较使用LSD-t检验。结果免疫荧光染色显示,100μg/L组细胞生长良好,融合度超过90%。MTT法显示,不同浓度盐酸左西替利嗪组与对照组hDPC的增殖率差异有统计学意义(F = 42.22,P 0.05);100 μg/L组COX-2、PTGDS、GPR44 mRNA表达(0.84 ± 0.08,0.81 ±0.10,0.85 ± 0.09)低于对照组(F值分别为 1.97、2.17、2.66,均P < 0.05),PGF2α、AKT的表达(1.96 ± 0.25 1.74 ± 0.32)高于对照组(t值分别为3.66,7.32,均P < 0.05)。不同浓度盐酸左西替利嗪组PTGDS、PGD2、PGD2R水平差异均有统计学意义(P< 0.05 ),100 μg/L组PTGDS、PGD2、PGD2R蛋白水平均低于对照组(P <0.05).结论盐酸左西替利嗪可能通过抑制PGD2-GPR44通路,激活AKT信号通路,促进体外培养人毛乳头细胞的生长。

关键词：西替利嗪前列腺素秃发受体,G-蛋白偶联毛乳头细胞

基于新数据安全法规的汽车企业数据安全建设探析

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现代工业经济和信息化 2022年第2期12卷 130-132页

作者：韦菊梅张亮班定东陈炼松上汽通用五菱汽车股份有限公司广西汽车新四化重点实验室广西柳州545007

随着信息技术的高速发展,以大数据为主要特征的数据资源已成为国家基础战略性资源和社会生产的创新要素,各行各业的发展都离不开“数据”的支撑,然而近几年来,数据泄露事件频频发生,并且呈现逐年递增的趋势,如何保证个人数据、企业数据... 详细信息

随着信息技术的高速发展,以大数据为主要特征的数据资源已成为国家基础战略性资源和社会生产的创新要素,各行各业的发展都离不开“数据”的支撑,然而近几年来,数据泄露事件频频发生,并且呈现逐年递增的趋势,如何保证个人数据、企业数据乃至国家数据的安全也成为了社会关注的焦点。国家对于数据安全问题十分重视。自今年以来,《数据安全法》《个人信息保护法》等关于数据安全保护的律法相继出台,对于汽车行业来说,随着汽车智能化、网联化的不断发展,汽车与数据之间早已息息相关,新数据安全法规的出台势必对汽车企业带来不可低估的影响。主要梳理了当前汽车数据安全现状,并介绍了数据安全建设对于汽车企业发展的重要性,同时分析了新数据安全法规对于数据信息安全建设提出的要求以及新法规给汽车企业带来的影响,最后提出了完善汽车企业数据安全建设的管理建议。

关键词：数据泄露数据安全数据安全法规信息安全汽车企业

Effects of rape straw and red mud on extractability and bioavailability of cadmium in a calcareous soil

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Frontiers of Environmental Science & Engineering 2015年第3期9卷 419-428页

作者： Junxing YANG Liqun WANG jumei LI Dongpu wei Shibao CHEN Qingjun GUO Yibing MA Centre for Environmental Remediation Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China National Soil Fertility and Fertilizer Effects Long-term Monitoring Network Institute of Agrieulttnal Resources and Regional Planning Chinese Academy of Agricultural Sciences Beijing 100081 China The Key Laboratory of Resource Environment and GIS College of Resource Environment and Tourism Capital Normal University Beijing 100037 China

Screening of cost-effective soil amendments is important to develop ＂in situ＂ remediation techniques for cadmium （Cd） contaminated soils. In this study, different soil amendments, including red mud, a by-product of the alumina industry, and acid-treated, nano-treated by nanoparticle milling, nano and acid-treated red muds, zeolite, corn straw, and rape straw, were evaluated to immobilize Cd in two added levels （2 and 5 mg Cd·kg^-1 soil） in a calcareous soil by single and sequential extractions and by cucumber （Cucumis sativus L.） pot experiments. Results indicated that cruciferous rape straw significantly decreased the concentrations of water soluble, extractable Cd in soils, and Cd in cucumber plants, and it was more effective than gramineous corn straw. Also, red mud generally decreased the extractability and bioavailability of Cd added to calcareous soils more effectively than zeolite. Furthermore, the efficiency of red mud could be increased by the treatment of nano-particle milling due to the increase in specific surface area of red mud. It is potential to use rape straw and red mud as soil amendments to develop a cost-effective and efficient ＂in situ＂ rernediation technology for Cd mildly contaminated calcareous soils.

关键词： red mud rape straw cadmium immobilization calcareous soil

A novel silicone derivative of natural osalmid(DCZ0858)induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2118-2128页

作者： Kang Lu Bo Li Hui Zhang Zhijian Xu Dongliang Song Lu Gao Haiguo Sun Liping Li Yingcong Wang Qilin Feng Gege Chen Liangning Hu Rong wei Yongsheng Xie Dandan Yu Xiaosong Wu weiliang Zhu jumei Shi Department of Hematology Shanghai Tenth People’s HospitalTongji UniversitySchool of Medicine200072 ShanghaiChina Medical School of Nantong University 226001 NantongChina CAS Key Laboratory of Receptor Research Drug Discovery and Design CenterShanghai Institute of Materia MedicaChinese Academy of Sciences201203 ShanghaiChina

Diffuse large B-cell lymphoma(DLBCL)is a highly heterogeneous malignant tumor characterized by diffuse ***0858 is a novel small molecule with excellent antitumor effects in *** study explored in depth the inhibitory effect of DCZ0858 on DLBCL cell *** Counting Kit-8(CCK-8)and plate colony formation assays were used to evaluate cell proliferation *** cytometry was employed to analyze apoptosis and the cell cycle,and western blotting was used to quantify the expression of cell cycle *** results indicated that DCZ0858 inhibited cell growth in a concentration-dependent and time-dependent manner while inducing no significant toxicity in normal ***,DCZ0858 initiated cell apoptosis via both internal and external apoptotic ***0858 also induced cell cycle arrest in the G0/G1 phase,thereby controlling cell *** investigation of the molecular mechanism showed that the JAK2/STAT3 pathway was involved in the DCZ0858-mediated antitumor effects and that JAK2 was the key target for DCZ0858 *** of JAK2 partly weakened the DCZ0858-mediated antitumor effect in DLBCL cells,while JAK2 overexpression strengthened the effect of DCZ0858 in DLBCL ***,a similar antitumor effect was observed for DCZ0858 and the JAK2 inhibitor ruxolitinib,and combining the two could significantly enhance cancer-suppressive *** xenograft models showed that DCZ0858 inhibited tumor growth in vivo and had low toxicity in important organs,findings that were consistent with the in vitro *** summary,DCZ0858 is a promising drug for the treatment of DLBCL.

关键词： inhibited organs cycle