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Sex estimation in a Turkish population using Purkait’s triangle:a virtual approach by 3-dimensional computed tomography(3D-CT)

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Forensic Sciences Research 2022年第2期7卷 97-105页

作者： julieta g.garcía-donas Suna Ors Ercan Inci Elena F.Kranioti Oguzhan Ekizoglu Negahnaz Moghaddam Silke grabherr Centre for anatomy and human identification school of science and engineeringUniversity of DundeescotlandUK Department of radiology Bakirkoy Training and research hospitalistanbulTurkey Department of Forensic science University of cretecreteGreece University center of Legal Medicine Lausanne-geneva Lausanneswitzerland Unit of Forensic imaging and anthropology University center of Legal Medicine Lausanne-GenevaLausanneswitzerland Swiss human institute of Forensic Taphonomy University center of Legal Medicine Lausanne-GenevaLausanneswitzerland

Sex estimation is considered one of the first steps in the forensic identification *** and morphometrical differences between males and females have been used as means for morphoscopic and metric methods on both cranial and postcranial skeletal *** dry skeletal elements are not available,virtual data can be used as a *** present research explores 3-dimensional(3D)scans from a Turkish population to test a sex estimation method developed by Purkait(2005).Overall,296 individuals were used in this study(158 males and 138 females).Purkait’s triangle parameters were measured on computed tomography(CT)scans obtained from both right and left femora of each patient at the Bakirkoy *** Konuk Training Research Hospital(Istanbul,Turkey).Intra-and inter-observer errors were assessed for all variables through technical error of measurements *** asymmetry and sex differences were evaluated using parametric and non-parametric statistical *** and multivariate discriminant function analyses were then *** errors demonstrated an overall agreement within and between experts,as indicated by technical error of measurement(TEM)*** bilateral asymmetries were reported,and all parameters demonstrated a statistically significant difference between males and *** discriminant models were generated by applying single and combined parameters,producing a total correct sex classification ranging from 78.4%to 92.6%.In addition,over 67%of the total sample was accurately classified,with 95%or greater posterior *** study demonstrates the feasibility of 3D sex estimation using Purkait’s triangle on a Turkish population,with accuracy rates comparable to those reported in other *** is the first attempt to apply this method on virtual data and although further validation and standardisation are recommended for its application on dry bone,this research constitutes a signif

关键词： Forensic sciences forensic anthropology sex estimation computed tomography Purkait’s triangle

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Synthesis and characterization of carbon-TiO2-CeO2 composites and their applications in phenol degradation

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Journal of Rare Earths 2017年第6期35卷 551-558页

作者： Y.Lara-López g.garcía-Rosales J.Jiménez-Becerril Technological Institute of Toluca Posgrade and Research Division Ex-Rancho La Virgen S/N C.P. 50120 Metepec Mexico National Institute for NuclearResearch Chemistry Department. Carretera Mexico-Toluca S/N la Marquesa Ocoyoacac C.P. 52750 Mexico

The objective of this work was to synthesize particles of titanium oxide and cerium oxide supported on carbon, which was obtained through the pyrolysis of orange peel. The materials were characterized using scanning electron microscopy, X-ray diffraction, infrared spectroscopy, and the specific surface area from Brunauer-Emmett-Teller method. The photocatalytic properties of the synthesized materials were determined by the degradation of phenol in 30 mg/L aqueous solutions. TiO2-CeO2 particles were obtained with an average spherical size of 57 nm and were supported on the carbon surface; this material presented a specific surface area of 296 m2/g and degrades -40% of phenol after 240 min of UV irradiation.

关键词： phenol photocatalytic spherical pyrolysis irradiation Teller Brunauer ceria orange cerium

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Beyond neurodegeneration:engineering amyloids for biocatalysis

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Neural Regeneration Research 2025年第10期20卷 2915-2916页

作者： Andrea Bartolomé-Nafría Javier garcía-Pardo Salvador Ventura Institut de Biotecnologia i de Biomedicina(IBB)and Departament de Bioquímica i Biologia Molecular Universitat Autònoma de BarcelonaBellaterraBarcelonaSpain Hospital Universitari Parc Taulí Institut d’Investigaciói InnovacióParc Taulí(I3PT-CERCA)Universitat Autònoma de BarcelonaSabadellSpain

Amyloid fibrils are highly organized protein or peptide aggregates,often characterized by a distinctive supramolecular cross-β-sheet *** formation and accumulation of these structures have been traditionally associated with neural or systemic human diseases,such as Alzheimer’s disease,Parkinson’s disease,type-2 diabetes,or amyotrophic lateral sclerosis(Wei et al.,2017;Wittung-Stafshede,2023).

关键词： structure amyloid

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The emerging role of mesenchymal stem cell-derived extracellular vesicles to ameliorate hippocampal NLRP3 inflammation induced by binge-like ethanol treatment in adolescence

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Neural Regeneration Research 2025年第4期20卷 1153-1163页

作者： Susana Mellado María JoséMorillo-Bargues Carla Perpiñá-Clérigues Francisco garcía-garcía Victoria Moreno-Manzano Consuelo guerri María Pascual Department of Physiology School of Medicine and DentistryUniversity of ValenciaValenciaSpain Bioinformatics and Biostatistics Unit Príncipe Felipe Research CenterValenciaSpain Neuronal and Tissue Regeneration Laboratory Príncipe Felipe Research CenterValenciaSpain

Our previous studies have reported that activation of the NLRP3(NOD-,LRR-and pyrin domain-containing protein 3)-inflammasome complex in ethanol-treated astrocytes and chronic alcohol-fed mice could be associated with neuroinflammation and brain *** stem cell-derived extracellular vesicles(MSC-EVs)have been shown to restore the neuroinflammatory response,along with myelin and synaptic structural alterations in the prefrontal cortex,and alleviate cognitive and memory dysfunctions induced by binge-like ethanol treatment in adolescent *** the therapeutic role of the molecules contained in mesenchymal stem cell-derived extracellular vesicles,the present study analyzed whether the administration of mesenchymal stem cell-derived extracellular vesicles isolated from adipose tissue,which inhibited the activation of the NLRP3 inflammasome,was capable of reducing hippocampal neuroinflammation in adolescent mice treated with binge *** demonstrated that the administration of mesenchymal stem cell-derived extracellular vesicles ameliorated the activation of the hippocampal NLRP3 inflammasome complex and other NLRs inflammasomes(e.g.,pyrin domain-containing 1,caspase recruitment domain-containing 4,and absent in melanoma 2,as well as the alterations in inflammatory genes(interleukin-1β,interleukin-18,inducible nitric oxide synthase,nuclear factor-kappa B,monocyte chemoattractant protein-1,and C–X3–C motif chemokine ligand 1)and miRNAs(miR-21a-5p,miR-146a-5p,and miR-141-5p)induced by binge-like ethanol treatment in adolescent *** analysis further revealed the involvement of miR-21a-5p and miR-146a-5p with inflammatory target genes and NOD-like receptor signaling *** together,these findings provide novel evidence of the therapeutic potential of MSC-derived EVs to ameliorate the hippocampal neuroinflammatory response associated with NLRP3 inflammasome activation induced by binge drinking in adolescence.

关键词： adolescence binge-like ethanol treatment extracellular vesicles hippocampus mesenchymal stem cells neuroinflammation NOD-,LRR-and pyrin domain-containing protein 3(NLRP3)

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green ionic metal-organic frameworks as nanocatalysts for CO_(2)fixation

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Nano Research 2025年第1期18卷 260-269页

作者： Nuria Martín Miguel Maireles-Porcar Julián Sánchez Velandia Belén Altava Francisco g.Cirujano Eduardo garcía-Verdugo Departamento de Química Inorgánica y Orgánica Universidad Jaume IAv.Sos Baynats/nCastellóde la PlanaCastellón 12071Spain

Co,Ni,and Zn iso-reticular coordination polymers of 2,5-dihydroxyterphthalic acid(H_(2)dot)can be rapidly obtained under room temperature and aqueous conditions using either sodium or ammonium hydroxide as the bases to deprotonate the *** use of metal bromides and tetrabutylammonium hydroxide(TBAOH)as the base allows the green synthesis of ionic metal-organic frameworks(MOFs),characterized by X-ray diffraction(XRD),Fourier transform infrared(FTIR),scanning electron microscopy(SEM),thermo gravimetric analysis(TgA),H-nuclear magnetic resonance(NMR),elemental analysis,and X-ray photoelectron spectroscopy(XPS),and employed in the pressure,solvent,and additive-free CO_(2)fixation to epoxides by its cycloaddition to epichlorohydrin,exhibiting a cooperative behavior between the MOF and the ionic liquid formed within the framework,achieving TONs of the confined tetrabutylammonium bromide(TBABr)up to 700.

关键词： metal-organic frameworks(MOFs) ionic liquids heterogeneous catalysis CO_(2)conversion

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Reassessing the AMPK-MTORC1 balance in autophagy in the central nervous system

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Neural Regeneration Research 2025年第11期20卷 3209-3210页

作者： Marta garcía-Juan Mario Villa Irene Benito-Cuesta Lara Ordónez-gutiérrez Francisco Wandosell Centro de Biología Molecular“Severo Ochoa”(CSIC-UAM) Nicolas Cabrera 1Universidad Autónoma de MadridMadridSpain Fisiología Animal Departamento de BiologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Department of Clinical Neuroscience CMM Karolinska Universitetssjukhuset SolnaStockholmSweden Departamento de Bioquímica y Biología Molecular Universidad Complutense de MadridMadridSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) MadridSpain

Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and *** cellular process is evolutionarily highly conserved to quality control of many proteins and dysfunctional organelles,which finally recycle components as amino *** process is effective during normal physiology as part of anabolism and plays an additional important role during starvation(Dikic and Elazar,2018).Different types of autophagy have been chara cterized based on their dynamic,mechanism of action,target substrates,and protein *** of them are macroautophagy(hereafter called"autophagy"),microa utophagy,and chape rone-media ted autophagy(Fleming et al.,2022).

关键词： homeostasis system hereafter

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Dendritic spine degeneration:a primary mechanism in the aging process

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Neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： gonzalo Flores Leonardo Aguilar-Hernández Fernado garcía-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(INCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto Nacional de Medicina genómica(INMEgEN) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(gM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

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Isothermal hydrogen absorption process of Pd-capped Mg films traced by ion beam techniques and optical methods

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Journal of Magnesium and Alloys 2024年第9期12卷 3675-3684页

作者： D.Abejón P.Prieto J.K.Kim A.Redondo-Cubero M.L.Crespillo F.Leardini I.J.Ferrer g.garcía J.R.Ares Departamento de Fisica de Materiales Universidad Autónoma de MadridMadrid28049Spain Centro de Micro-Análisis de Materiales(CMAM) Universidad Autónoma de MadridMadrid28049Spain Advanced Analysis Center KIST5 Hwarang-ro 14-gilSeoul 02792Republic of Korea Departamento de Física Aplicada Universidad Autónoma de MadridMadrid28049Spain Instituto Nicolás Cabrera Universidad Autónoma de MadridMadrid28049Spain

Pd-capped nanocrystalline Mg films were prepared by electron beam evaporation and hydrogenated under isothermal conditions to inves-tigate the hydrogen absorption process via ion beam techniques and in situ optical *** were characterized by different techniques such as X-ray diffraction(XRD)and scanning electron microscopy(SEM).Rutherford backscattering spectrometry(RBS)and elastic recoil detection analysis(ERDA)provided a detailed compositional depth profile of the films during ***-solid reaction kinetics theory applied to ERDA data revealed a H absorption mechanism controlled by H *** rate-limiting step was also confirmed by XRD *** diffusion coefficient(D)was also determined via RBS and ERDA,with a value of(1.1±0.1)·10^(−13)cm^(2)/s at 140℃.Results confirm the validity of IBA to monitor the hydrogenation process and to extract the control mechanism of the *** H kinetic information given by optical methods is strongly influenced by the optical absorption of the magnesium layer,revealing that thinner films are needed to extract further and reliable information from that technique.

关键词： Magnesium hydride Hydrogen absorption Ion beam techniques Optical tracing Absorption mechanism

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An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

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A murine model of dengue virus infection in suckling C57BL/6 and BALB/c mice

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Animal Models and Experimental Medicine 2021年第1期4卷 16-26页

作者： Alana B.Byrne Ayelén g.garcía Jorge M.Brahamian Aldana Mauri Adrián Ferretti Fernando P.Polack Laura B.Talarico Fundación INFANT Buenos AiresArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Buenos AiresArgentina

Dengue is a significant public health concern across tropical and subtropical regions worldwide,principally causing disease in *** young children are at increased risk of severe manifestations of dengue *** mechanism of dengue disease in this population is not fully *** this study,we present a murine model of dengue virus primary infection in suckling C57BL/6 and BALB/c mice in order to investigate disease ***-day-old C57BL/6 mice intraperitoneally infected with DENV-2 NgC were more susceptible to infection than BALB/c mice,showing increased liver enzymes,extended viremia,dissemination to organs and histological alterations in liver and small ***,the immune response in DENV-infected C57BL/6 mice exhibited a marked Th1 bias compared to BALB/c *** findings highlight the possibility of establishing an immunocompetent mouse model of DENV-2 infection in suckling mice that reproduces certain signs of disease observed in humans and that could be used to further study agerelated mechanisms of dengue pathogenesis.

关键词： BALB/c C57BL/6 dengue virus mouse model suckling mice

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