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Promoting Older Adults' Engagement in Disaster Recovery Through Supportive Relationships, Partnerships, and Collaboration: Perspectives of Social Work Practitioners and Human Service Professionals

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International Journal of Disaster Risk Science 2024年第2期15卷 265-276页

作者： julie l.drolet Mahed Choudhury Faculty of Social Work University of CalgaryEdmontonAB T5J 4P6Canada

Shifting demographics—that is, the growing number of older adults in Canada and internationally—and intersecting climatic risks create a complex landscape of aging in place in disaster contexts. Some older adults are vulnerable due to their underlying health conditions and limited physical mobility. Yet they also exhibit resilience in a distinct manner, owing to their wealth of knowledge, wisdom, and ability to navigate adversities. This article elucidates potential avenues for promoting the involvement of older adults in disaster recovery efforts. Our intention is to recognize and foster older adult resilience and mitigate vulnerability by drawing upon insights from the study titled “In the Aftermath of the 2016 Alberta Wildfires: The Role of Social Work Practitioners and Human Service Professionals in long-Term Disaster Recovery.” Employing a qualitative research approach, that study recruited 51 participants for semistructured interviews and focus groups. A thematic analysis of the collected data unveiled the pivotal roles played by social workers and human service practitioners in facilitating recovery from the 2016 wildfires in the research. Notably, three overarching themes emerged concerning the promotion of older adults' involvement in disaster recovery: fostering supportive relationships, building partnerships and enhancing collaboration, and addressing ongoing challenges. These findings offer valuable insights into how social work practitioners and human service professionals can effectively facilitate the engagement of older adults in disaster recovery initiatives. This article emphasizes the significance of actively promoting the participation of older adults in disaster mitigation efforts, thereby fostering greater resilience within communities.

关键词： Alberta wildfires Canada Disaster recovery Older adults Partnerships and collaboration Social work

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Promoting Older Adults' Engagement in Disaster Settings: An Introduction to the Special Issue

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International Journal of Disaster Risk Science 2024年第2期15卷 181-185页

作者： Haorui Wu Christine AWalsh julie ldrolet Kyle Breen Faculty of Health School of Social WorkDalhousie UniversityHalifaxNS B3H 4R2Canada Faculty of Social Work University of CalgaryCalgaryAB T2N 1N4Canada Faculty of Social Work Central&Northern Alberta RegionUniversity of CalgaryEdmontonAB T5J 4P6Canada

1 Introduction Globally, surging extreme events and the escalating aging population present ongoing and severe challenges to the full spectrum of international community development(for example, social, health, and ec... 详细信息

关键词： extreme challenges economic

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Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics

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Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-Jan Serneels julie D.De Schutter lies De Groef lieve Moons Steven Bergmans KU leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology will facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination

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A MEASURE OF SUPPlY CHAIN COMPlEXITY INCORPORATING VIRTUAl ARCS

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Journal of Systems Science and Systems Engineering 2015年第4期24卷 486-499页

作者： julie Drzymalski Department of Industrial Engineering and Engineering Management Western New England University

Increased globalization, as well as the ability to have virtual supply chain partners, has had numerous effects on supply chains. While some of these effects are positive, making more resilient supply chains, there are also the negative effects of scale ~nd complexity, making these supply chains more challenging than ever to manage. Having a means to measure the complexity is crucial for today＇s managers to make more informed decisions. This measure must not only account for the number of arcs, but the amount of information and material carried on it, as well as incorporate the benefit that virtual arcs add to the network by increasing efficiency and reducing information, product and financial transfer costs and time. This research utilizes newer models in network clustering and complexity theory to make them applicable to supply chains and creates a new, practical approach to measuring supply chain complexity which can be easily implemented by practitioners.

关键词： Supply chain complexity clustering virtual networks

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The impact of personality on the success of prospecting behavior in changing landscapes

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Current Zoology 2015年第3期61卷 557-568页

作者： John Curtis BURKHAlTER Nina H. FEFFERMAN julie l. lOCKWOOD Graduate Program in Ecology and Evolution Department of Ecology Evolution and Natural Resources Rutgers University 14College Farm Rd. New Brunswick NJ 08901 USA

Personality can play a large role in dispersal decisions, influencing how each individual estimates and values ex- pected costs versus benefits of ventnring out to explore the unknown. We contrast the impact of persistence on fitness using deci- sion theory models to examine the relative success of prospecting movement （which is a widespread behavior used by animals to explore available breeding habitat before determining where to settle） in different landscapes among individuals with different personalities. While evaluating trends in the costs and benefits of movement we provide a quantifiable measure of the impacts of relative tenacity in prospecting behavior on fitness gains/losses. Our model results predict that, regardless of landscape composi- tion, individuals with greater tenacity in prospecting strategy have reduced fitness gains relative to individuals who are more willing to both initiate novel strategies, but then also abandon the new strategy rapidly if initial search does not seem fruitful. We show that fitness gains from choosing an appropriate prospecting strategy （i.e. abandoning poor habitat or staying in rich habitat） can be very high, indicating a potentially large influence from personality on fitness. Importantly, the model predicts that relative fitness gains are highly dependent on the availability of high quality habitat in the landscape, even if the difference under varying fitness outcomes between poor and rich habitat was substantial

关键词： Prospecting Tradeoff Movement Decision theory Personality Behavior

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Corneal injection track: an unusual complication of intraocular lens implantation and review

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International Journal of Ophthalmology(English edition) 2015年第3期8卷 631-633页

作者： julie Y.C.lok Alvin l.Young Department of Ophthalmology & Visual Sciences the Chinese University of Hong Kong Prince of Wales Hospital Alice Ho Miu ling Nethersole Hospital

Phacoemulsification is the main gold standard for cataract operation in the developed world together with foldable intraocular lens(IOl) implantation by injection,allowing for stable wound construction and less postoperative astigmatism. It is a safe procedure with high success rate with the advancement in machines,improvement of IOl injection systems and further maturation of surgeons’ techniques. Despite the large number of operations performed every day, foldable IOl injection leading to an intra-stromal corneal track is a very rare complication. We report a case of this unusual finding in a 70-year-old gentleman who has undergone cataract operation in November 2011 in our hospital and will review on the complications related to foldable IOl injection.

关键词： foldable intraocular lens phacoemulsification cornea complications

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Time dependent integration of matrix metalloproteinases and their targeted substrates directs axonal sprouting and synaptogenesis following central nervous system injury

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Neural Regeneration Research 2014年第4期9卷 362-376页

作者： linda l.Phillips julie l.Chan Adele E.Doperalski Thomas M.Reeves Department of Anatomy and Neurobiology Virginia Commonwealth UniversityRichmondVAUSA

Over the past two decades, many investigators have reported how extracellular matrix molecules act to regulate neuroplasticity. The majority of these studies involve proteins which are targets of matrix metalloproteinases. Importantly, these enzyme/substrate interactions can regulate degenerative and regenerative phases of synaptic plasticity, directing axonal and dendritic reorganization after brain insult. The present review first summarizes literature support for the prominent role of matrix metalloproteinases during neuroregeneration, followed by a discussion of data contrasting adaptive and maladaptive neuroplasticity that reveals time-dependent metalloproteinase/substrate regulation of postinjury synaptic recovery. The potential for these enzymes to serve as therapeutic targets for enhanced neuroplasticity after brain injury is illustrated with experiments demonstrating that metalloproteinase inhibitors can alter adaptive and maladaptive outcome. Finally, the complexity of metalloproteinase role in reactive synaptogenesis is revealed in new studies showing how these enzymes interact with immune molecules to mediate cellular response in the local regenerative environment, and are regulated by novel binding partners in the brain extracellular matrix. Together, these different examples show the complexity with which metalloproteinases are integrated into the process of neuroregeneration, and point to a promising new angle for future studies exploring how to facilitate brain plasticity.

关键词： neuroregeneration reactive synaptogenesis matrix metalloproteinases brain injury adaptive and maladaptive neuroplasticity metalloproteinase inhibition osteopontin lipocalin 2

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Mental and physical symptoms associated with lower social support for patients with hepatitis C

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World Journal of Gastroenterology 2006年第29期12卷 4665-4672页

作者： julie A Blasiole laura Shinkunas Douglas R laBrecque Robert M Arnold Susan l Zickmund VA Pittsburgh Healthcare System Center for Health Equity Research and Promotion PittsburghPAUnited States Department of Epidemiology University of Iowa School of Public Health Iowa CityIAUnited States Department of Internal Medicine University of Iowa Hospitals and Clinics Iowa CityIAUnited States Department of Medicine University of Pittsburgh School of Medicine PittsburghPAUnited States Department of Medicine University of Pittsburgh School of Medicine VA Pittsburgh Healthcare SystemCenter for Health Equity Research and PromotionPittsburghPAUnited States

AIM: To systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study. METHODS: Patients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support. RESUlTS: A total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP. CONClUSION: Patients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting

关键词： Hepatitis C Social support Depression Anxiety Quality of life Stigmatization

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γδ T cells,Tregs and epithelial cells interact with Il-33 in the lung

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Cellular & Molecular Immunology 2021年第4期18卷 790-791页

作者： julie Darrigues julie C.Ribot Institute de Medicina Molecular Joao lobo Antunes Faculdade de MedicinaUniversidade de LisboaLisbonPortugal

Mucosal barriers are composed of an organized network of tightly joined cells that act as a critical first line of defense against *** their tissue hom ing properties and ability to sense environmental signals,gamma d... 详细信息

关键词： lung delta network

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Hypoxia-inducible factor-1a restricts the anabolic actions of parathyroid hormone

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Bone Research 2014年第1期2卷 33-42页

作者： julie l Frey David P Stonko Marie-Claude Faugere Ryan C Riddle Department of Orthopaedic Surgery Johns Hopkins University School of Medicine Division of Nephrology Bone & Mineral Metabolism University of Kentucky Veterans Administration Medical Center

The hypoxia inducible factors （Hifs） are evolutionarily conserved transcriptional factors that control homeostatic responses to low oxygen. In developing bone, Hif-1 generated signals induce angiogenesis necessary for osteoblast specification, but in mature bone, loss of Hif-1 in osteoblasts resulted in a more rapid accumulation of bone. These findings suggested that Hif-1 exerts distinct developmental functions and acts as a negative regulator of bone formation. To investigate the function of Hif-1a in osteoanabolic signaling, we assessed the effect of Hif-1a loss-of-function on bone formation in response to intermittent parathyroid hormone （PTH）. Mice lacking Hif-1a in osteoblasts and osteocytes form more bone in response to PTH, likely through a larger increase in osteoblast activity and increased sensitivity to the hormone. Consistent with this effect, exposure of primary mouse osteoblasts to PTH resulted in the rapid induction of Hif-1a protein levels via a post-transcriptional mechanism. The enhanced anabolic response appears to result from the removal of Hif-1a-mediated suppression of β-catenin transcriptional activity. Together, these data indicate that Hif-1a functions in the mature skeleton to restrict osteoanabolic signaling. The availability of pharmacological agents that reduce Hif-1a function suggests the value in further exploration of this pathway to optimize the therapeutic benefits of PTH.

关键词： PTH Hypoxia-inducible factor-1a restricts the anabolic actions of parathyroid hormone Figure

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