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ENERGY ESTIMATES FOR DELAY DIFFUSION-REACTION EQUATIONS

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Journal of Computational Mathematics 2008年第4期26卷 536-553页

作者： J.A.ferreira P.M.daSilva CMUC-Departamento Departamento

In this paper we consider nonlinear delay diffusion-reaction equations with initial and Dirichlet boundary conditions. The behaviour and the stability of the solution of such initial boundary value problems （IBVPs） are studied using the energy method. Simple numerical methods are considered for the computation of numerical approximations to the solution of the nonlinear IBVPs. Using the discrete energy method we study the stability and convergence of the numerical approximations. Numerical experiments are carried out to illustrate our theoretical results.

关键词： Delay diffusion reaction equation Energy method Stability Convergence.

Combined Oxidative Phosphorylation Deficiency-20-Exome as a Diagnostic Implement

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Journal of Biosciences and Medicines 2024年第6期12卷 7-12页

作者： Paulo Roberto Matos-Neto Lucas Antonissen Lima Verde Airton ferreira da Ponte-Filho Luís Eduardo Oliveira Matos Amandha Espavier Trés Paulo Roberto Lacerda Leal Gerardo Cristino-Filho Regina Coeli de Carvalho Porto Carneiro Faculty of Medicine Federal University of Cear Sobral Cear Brazil Department of Neurosurgery Federal University of Cear Sobral Cear Brazil Department of Neuropediatrics Federal University of Cear Sobral Cear Brazil

Mitochondrial disorders are phenotypically varied, with serious clinical repercussions. Among them, there is the deficiency of combined oxidative phosphorylation of type 20, which occurs due to a defect in the VARS2 gene. This article presents a case of a 2-year-old female with progressive myoclonic epilepsy and psychomotor regression, with refractoriness to multiple anticonvulsants. The diagnosis was only made after the examination was carried out. Therefore, this article highlights the aspects of this rare disease and the importance of the exome for the diagnosis of rare conditions.

关键词： Oxidative Phosphorylation Epilepsy Exome Mitochondrial Defect VARS2

Analysis of the evidence of related factors,associated conditions and at-risk populations of the NANDA-I nursing diagnosis insomnia

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International Journal of Nursing Sciences 2020年第4期7卷 466-476,I0008页

作者： Lidia Santiago Guandalini Eduarda ferreira da Silva juliana de Lima Lopes Vinicius Batista santos Camila Takao Lopes Alba Lúcia Bottura Leite de Barros Escola Paulista de Enfermagem Universidade Federal de Sao PauloSao PauloBrazil Sao Paulo Hospital Sao PauloBrazil

Objectives:To summarize evidence in the literature on the predictors of insomnia in adults and to determine correspondences with diagnostic indicators of the NANDA-I diagnosis ***:An integrative review performed in Pubmed,Virtual Health Library and ***-eight articles published in Portuguese,English or Spanish from 2011 to 2018 were *** analysis of correspondence between the predictors and the NANDA-I related factors and associated conditions for Insomnia was ***:There was a correspondence of the predictors found in this review with NANDA-I related factors and associated conditions,except for grieving and frequent naps during the ***,caffeine intake,dysfunctional sleep beliefs,obesity and caregiver role strain are possible new related factors;chronic illness is a possible new associated condition and individuals going through changes in marital status,economically disadvantaged,female gender,increasing age and night shift worker are possible new at-risk ***:The predictors of insomnia that had a correspondence with the NANDA-I elements can support the evidence base of the nursing *** predictors found without a correspondence with the diagnosis can be considered for inclusion in the NANDA-I classification,thereby supporting the clinical reasoning of nurses and students.

关键词： Adult Insomnia Nursing diagnosis Sleep initiation and maintenance disorders

Analysis of the impact of large scale seismic retrofitting strategies through the application of a vulnerability-based approach on traditional masonry buildings

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Earthquake Engineering and Engineering Vibration 2017年第2期16卷 329-348页

作者： Tiago Miguel ferreira Rui Maio Romeu Vicente ISISE Department of Civil EngineeringUniversity of MinhoCampus de Azurém RISCO Department of Civil EngineeringUniversity of AveiroCampus Universitário de Santiago

The buildings＇ capacity to maintain minimum structural safety levels during natural disasters, such as earthquakes, is recognisably one of the aspects that most influence urban resilience. Moreover, the public investment in risk mitigation strategies is fimdamental, not only to promote social and urban and resilience, but also to limit consequent material, human and environmental losses. Despite the growing awareness of this issue, there is still a vast number of traditional masonry buildings spread throughout many European old city centres that lacks of adequate seismic resistance, requiring therefore urgent retrofitting interventions in order to both reduce their seismic vulnerability and to cope with the increased seismic requirements of recent code standards. Thus, this paper aims at contributing to mitigate the social and economic impacts of earthquake damage scenarios through the development of vulnerability-based comparative analysis of some of the most popularretrofitting techniques applied after the 1998 Azores earthquake. The influence of each technique individually and globally studied resorting to a seismic vulnerability index methodology integrated into a GIS tool and damage and loss scenarios are constructed and critically discussed. Finally, the economic balance resulting from the implementation of that techniques are also examined.

关键词： urban resilience masonry buildings retrofitting strategies vulnerability-based approach loss estimation

Communicating with the non-dominant hemisphere:Implications for neurological rehabilitation

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Neural Regeneration Research 2013年第13期8卷 1236-1246页

作者： Fabricio ferreira de Oliveira Sheilla de Medeiros Correia Marin Paulo Henrique ferreira Bertolucci Department of Neurology and Neurosurgery Escola Paulista de Medicina Federal University of So Paulo (UNIFESP) So Paulo SP

Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recovery after brain injury to the dominant hemisphere seem to be relatively stereotyped, including activations of perilesional areas in the acute phase and of homologues of language areas in the non-dominant hemisphere in the subacute phase, later returning to dominant hemisphere activation in the chronic phase. Plasticity mechanisms reopen the critical period of language development, more specifically in what leads to disinhibition of the non-dominant hemisphere when brain lesions affect the dominant hemisphere. The non-dominant hemisphere plays an important role during recovery from aphasia, but currently available rehabilitation therapies have shown limited results for efficient language improvement. Large-scale randomized controlled trials that evaluate well-defined interventions in patients with aphasia are needed for stimulation of neuroplasticity mechanisms that enhance the role of the non-dominant hemisphere for language recovery. Ineffective treatment approaches should be replaced by more promising ones and the latter should be evaluated for proper application. The data generated by such studies could substantiate evidence-based rehabilitation strategies for patients with aphasia.

关键词： neural regeneration reviews linguistics aphasia language speech non-dominant hemisphere disability evaluation prognosis cerebrum function grants-supported paper neuroregeneration

Seasonal testicular changes in Dendropsophus minutus Peters, 1872 (Anura, Hylidae)

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BIOCELL 2012年第2期36卷 57-62页

作者： ADELINA ferreira MAHMOUD MEHANNA Universidade Federal de Mato Grosso(UFMT) Instituto de BiociênciasCuiabáMTBrasil Universidade Estadual Paulista Julio de Mesquita Filho(UNESP) Laboratório de Biologia de PeixesPós-graduação em ZoologiaBotucatuSPBrasil

The reproductive cycle in anurans may be either continuous or *** differences may be connected to seasonal climate changes and/or to anthropic *** adult male individuals of the Dendropsophus minutus species were collected during one year,in the municipality of Chapada dos Guimarães(Mato Grosso,Brazil).The testicles were studied under light and transmission electron *** variations were observed when the diameter of the seminiferous tubules and the thickness of the interstitial tissue were ***,changes in spermatogenesis were conspicuous and indicated that the reproductive cycle of *** in Chapada dos Guimarães is discontinuous and seems related to variations in air temperature and rainfall.

关键词： spermatogenesis reproduction anura ultrastructure Chapada dos Guimarães

Evidence-based Practice of Chinese Medicine in Physical Rehabilitation Science

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Chinese Journal of Integrative Medicine 2013年第10期19卷 723-729页

作者： Arthur de Sá ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Program of Rehabilitation ScienceCentro Universitario Augusto MottaRio de JaneiroRJBrazil(21041-021) Department of Physical Therapy UniversidadeSalgado de OliveiraNiteróiRJBrazil(21041-021)

Chinese medicine is among other traditional medical systems practiced either as a coadjutant intervention to Greek medicine or as the unique therapeutic intervention for illness prevention, treatment or rehabilitation. The complete spectrum from that traditional system includes acupuncture and moxibustion, herbal and food therapy, massage therapy （tuina）, physical exercises （taijiquan）, and breathing exercises （qigong）. In this article, it is presented several randomized controlled trials and systematic reviews on the application of all therapeutic modalities from Chinese medicine in the physical rehabilitation scenario. The discussed studies encompasses both ＂positive＂ and ＂negative＂ results of Chinese medicine intervention for disabilities due to illnesses of the nervous, musculoskeletal or cardiovascular systems. Additionally, the importance of the personalized approach for Chinese medicineand rehabilitation is emphasized together with the need for reproducible methods for pattern differentiation and intervention selection. Chinese medicine resources are recognized as promising methods for therapeutic rehabilitation and can be incorporated into the rehabilitation science. The wide variety of therapeutic resources explains why Chinese medicine is currently a multidisciplinary practice for health protection and promotion, early diagnosis and treatment as well as rehabilitation with roles in the public health care system.

关键词： rehabilitation physical therapy Chinese medicine

Unsupervised learning of load signatures to estimate energy-related building features using surrogate modelling techniques

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Building Simulation 2023年第7期16卷 1273-1286页

作者： Shane ferreira Burak Gunay Araz Ashouri Scott Shillinglaw Carleton University OttawaK1S 5B6Canada National Research Council Canada OttawaK1A 0R6Canada

Characterization of an existing building’s energy-related features is critical to inform maintenance and retrofit ***,existing field-scale characterization methods tend to be labour intensive,invasive,and require high fidelity longitudinal data gathered through tightly regulated *** highlights the need for a low cost,scalable,and efficient screening *** paper puts forward a surrogate model-based approach to rapidly estimate energy-related building *** this end,EnergyPlus models for 12 midrise office archetypes,all with a rectangular footprint,are *** thousand variants of each archetype are generated by altering envelope,causal heat gain,and heating,ventilation,and air conditioning operation features.A unique load signature is derived for each variant’s heating and cooling energy *** parameters of the load signatures are clustered,then each cluster is associated with a set of plausible energy-related *** accuracy of the results was evaluated using five test buildings not seen by the *** method could effectively identify building features with reasonable accuracy and no significant degradation in performance across all 12 archetypes.

关键词： remote characterization energy-related building features surrogate modelling cluster analysis

Sub-chronic effects of a Phthirusa pyrifolia aqueous extract on reproductive function and comparative hormone levels in male rats

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Asian Pacific Journal of Tropical Biomedicine 2016年第3期6卷 202-210页

作者： Romero Marcos Pedrosa Brandao-Costa Vivianne ferreira Araujo Elizabeth Neves Maria Tereza santos Correia Ana Lucia Figueiredo Porto Maria das Gracas Carneiro-da-Cunha Department of Biochemistry Center of Biological Sciences Federal University of Pernambuco Keizo Asami Laboratory of Imunopathology LIKA/UFPE Department of Anatomy Federal University of Pernambuco Department of Animal Morphology and Physiology Federal Rural University of Pernambuco Keizo Asami Laboratory of Imunopathology LIKA/UFPE

Objective: To explore the effects of aqueous extract from Phthirusa pyrifolia leaves(67 mg/kg body weight for 12 days) on the reproductive function of male Wistar rats through oral ***: Animals(n = 30), aged 13 weeks and weighing(378.5 ± 5.0) g, were housed in a vivarium under controlled environmental conditions [photoperiod of 12 h light/dark,temperature of(23 ± 1)C] and were fed standard rations ad libitum. The experiment ran for 12 days, wherein animals were divided into three groups: negative control(n = 6)received water, positive control(n = 12) with finasteride at a concentration of 1.0 mg/kg;and a test group(n = 12) submitted to aqueous extract. At the end of the experiment, the animals were sacrificed and submitted to ***: The morphological results of the testes showed that the aqueous extract induced significant changes in the diameter and cross-sectional area of the seminiferous tubules as well as the thickness of the seminiferous epithelium. Furthermore, the extract was able to abruptly decrease testosterone concentrations by about 81.88% in the treated group when compared with the negative control,(47.0 ± 4.8) ng/d L and(255.0 ± 2.0) ng/d L,respectively, and 76.8%,(211.0 ± 8.7) ng/d L, when compared with finasteride. However,the extract causes neither liver damage nor impairment of renal ***: These results suggest that the high amounts of flavonoids shown to be in the extract may be responsible for its hepato-protective effects and suggest a possible decrease in the libido and reproduction of rats.

关键词： Reproductive function Phytochemical Testosterone Finasteride Phthirusa pyrifolia