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Evaluation of.Montreal cognitive assessment f.r the dif.erential diagnosis of.mild cognitive impairment and Alzheimer’s disease in elderly patients with more than 5 years of.schooling: Data f.om a Brazilian sample

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Advances in Aging Research 2013年第4期2卷 121-129页

作者： José M. Montiel juliana f. cecato Daniel Bartholomeu José Eduardo Martinelli f.EO University Center Osasco Brazil Jundiai Medical School Jundiaí Brazil

Background: Diagnostic investigation of.dementia is based on a series of.tests which lie the neuropsychological evaluations. The Montreal Cognitive Assessment (MoCA) was developed as an instrument to recognize Mild Cognitive Impairment (MCI) and initial cases of.Alzheimer’s disease. The present study aims to evaluate the predictive value of.Brazilian MoCA test version in a sample of.elderly above 5 years of.education. Methods: Cross-sectional study with 136 elderly, above 60 years old at least 5 years of.education. Diagnostic criteria is based on clinical and neuropsychological data classif.ed Alzheimer’s disease n = 52, MCI n = 45 e normal controls n = 39. MoCA test was compared with Cambridge Cognitive Examination, Mini-Mental State Exam, Verbal f.uency, Clock Drawing Test, Geriatric Depression Scale and Pf.f.er f.nctional Activities Questionnaire. Accuracy was evaluated by receiver operating characteristic (ROC) curve analyses. Pearson correlation coef.icient was used to compare the MoCA with the other tests. It was also used logistic regression analysis to identif. the main risk f.ctors f.r the diagnostic groups. Results: MoCA was the best test to dif.erentiate Alzheimer’s disease cases f.om MCI with 86.5% sensitivity and 75.6% specif.city. f.rthermore, analyzes of.correlation test showed that MoCA correlates robust way of.already validated with other tests and wide application inBrazil. Conclusions: It can be concluded that MoCA is a good screening tool f.r investigation of.MCI among the elderly in Brazil with over 5 years of.schooling. Studies with larger numbers of.participants are needed to f.rther validate the test also f.r elderly people with low education.

关键词： Elderly MoCA Mild Cognitive Impairment Alzheimer’s Disease Neuropsychological Tests

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