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Prevalence and Factors Associated with Concomitant Chinese Medicine Use by Rheumatoid Arthritis Patients in A Multi-Ethnic Asian Population

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Chinese Journal of Integrative Medicine 2022年第3期28卷 223-228页

作者： HUANG You-yi XIN Xiao-hui Rehena Sultana julian thumboo FONG Kok Yong Duke-NUS Medical School Singapore Department of Rheumatology and Immunology Singapore General HospitalSingapore Medicine Academic Clinical Program Division of MedicineSingapore General HospitalSingapore Centre for Quantitative Medicine Duke-NUS Medical SchoolSingapore

Objective:To determine the prevalence,factors associated with and patterns of concomitant Chinese medicine(CM)with Western treatment use among patients with rheumatoid arthritis(RA)in a tertiary referral centre(Singapore General Hospital)in ***:We conducted a cross-sectional intervieweradministered survey of a consecutive sample of patients with RA in Singapore General Hospital centre regarding their CM use including data on patient demographics,disease characteristics,concomitant use of CM and reasons,concerns and disclosure patterns from March to August *** and multivariate logistic regression analyses were performed to determine the associations of CM ***:Prevalence of CM use among the 258 patients surveyed(male:female 42:216;Chinese:Malay:Indian 191:29:34;mean age:61 years;mean duration of RA:10 years)was 46.1%(119/258).On muutivariate analysis,Chinese ethnicity(OR,95%CI:4.11,1.49-11.36),Chinese speakers(OR,95%CI:2.35,1.03-5.54),middle-income group(OR,95%CI:2.53,1.01-6.31)and greater learned helplessness(OR,95%CI:1.13,1.04-1.22)were significantly associated with CM *** CM users disclosed their CM use to CM physicians(87.3%,96/110),sought advice from them on treatment interactions(59.4%,57/96)and how best to combine treatments(49.0%,47/96)than did so with rheumatologists(42.0%,50/119;40.0%,20/50;and 42.0%,21/50,respectively).Forty-two percentage(29/69)of patients who concealed CM use from rheumatologists because their rheumatologists did not specifically enquire about CM ***:Concomitant CM use among patients with RA treated in a tertiary referral centre in Singapore is high but voluntary disclosure is *** associations identified can help doctors identify and enquire about CM use,minimizing potential adverse interactions.

关键词： pevalence rheumatoid arthritis Chinese medicine complementary therapies

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Effectiveness of mindfulness-based interventions on the well-being of healthcare workers:a systematic review and meta-analysis

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General Psychiatry 2024年第3期37卷 335-344页

作者： Natasha Yixuan Ong Finn Jing Jie Teo Jane Zi Ying Ee Chun En Yau julian thumboo Hiang Khoon Tan Qin Xiang Ng NUS Yong Loo Lin School of Medicine National University of SingaporeSingapore Health Services Research Unit Singapore General HospitalSingapore SingHealth Duke-NUS Medicine Academic Clinical Programme Duke-NUS Medical SchoolSingapore Singhealth Duke-NUS Global Health Institute Singapore Duke Global Health Institute Duke UniversityDurhamNorth CarolinaUSA Division of Surgery and Surgical Oncology Singapore General HospitalSingapore Saw Swee Hock School of Public Health National University of Singapore and National University Health SystemSingapore

Background Growing evidence attests to the efficacy of mindfulness-based interventions(MBIs),but their effectiveness for healthcare workers remains *** To evaluate the evidence for MBIs in improving healthcare workers’psychological *** A systematic literature search was conducted on Medline,Embase,Cumulative Index for Nursing and Allied Health Literature,PsycINFO and Cochrane Central Register of Controlled Trials up to 31 August 2022 using the keywords‘healthcare worker’,‘doctor’,‘nurse’,‘allied health’,‘mindfulness’,‘wellness’,‘workshop’and‘program’.Randomised controlled trials with a defined MBI focusing on healthcare workers and quantitative outcome measures related to subjective or psychological well-being were eligible for inclusion.R V.4.0.3 was used for data analysis,with the standardised mean difference as the primary outcome,employing DerSimonian and Laird’s random effects *** of Recommendations,Assessment,Development and Evaluation framework was used to evaluate the quality of ***’s Risk of Bias 2 tool was used to assess the risk of bias in the included *** A total of 27 studies with 2506 participants were included,mostly from the USA,involving various healthcare *** such as stress reduction programmes,apps,meditation and training showed small to large effects on anxiety,burnout,stress,depression,psychological distress and job strain outcomes of the *** effects were also seen in self-compassion,empathy,mindfulness and ***,long-term outcomes(1 month or longer postintervention)varied,and the effects were not consistently *** MBIs offer short-term benefits in reducing stress-related symptoms in healthcare *** review also highlights limitations such as intervention heterogeneity,reduced power in specific subgroup analyses and variable study quality.

关键词： nurse sustained workers

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Protocol for a randomized controlled trial of electroacupuncture in the management of patients with axial spondyloarthritis in Singapore(E-AcuSpA)

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Rheumatology & Autoimmunity 2021年第2期1卷 104-114页

作者： Warren Fong Yu Heng Kwan Su-An Quek Ader Lim Chiah Yuen Wong Shin Yoong Chua Hui Chin Tan Clara Eng Choy Tip Tan Bao Qiang Dong Youyi Huang Chuen Seng Tan Bee Choo Tai Ting Hui Woon Jie Kie Phang Hwee Ling Koh Ying Ying Leung julian thumboo TrulsØstbye Department of Rheumatology and Immunology Singapore General HospitalSingaporeSingapore Duke-NUS Medical School SingaporeSingapore Department of Medicine Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Internal Medicine Residency SingHealthSingaporeSingapore Programme in Health Services and Systems Research Duke-NUS Medical SchoolSingaporeSingapore Department of Pharmacy National University of SingaporeSingaporeSingapore Singapore Thong Chai Medical Institution SingaporeSingapore Acupuncture and Tuina College Liaoning University of Traditional Chinese MedicineShenyangLiaoningP.R.China Saw Swee Hock School of Public Health National University of SingaporeSingaporeSingapore

Background:Despite therapeutic advances,treatment of patients with axial spondyloarthritis(axSpA)continue to pose as a challenge as many do not respond well to conventional Western medications,such as nonsteroidal anti-inflammatory drugs(NSAIDs)and biologic diseasemodifying antirheumatic drugs(bDMARDs).Hence,acupuncture is a possible *** studies found electroacupuncture to be better than manual acupuncture,though no trials have been conducted in patients with *** clinical trial aims to evaluate the clinical efficacy,safety,and cost-effectiveness of electroacupuncture compared to manual acupuncture for patients with ***/Design:This randomized controlled trial will recruit 100 patients diagnosed with axSpA,who have active disease despite NSAIDs and *** patients will be randomized to receive either electroacupuncture or manual acupuncture in a 1:1 *** participants will receive standard rheumatologic care in addition to 20 acupuncture *** mean difference in Bath Ankylosing Spondylitis Disease Activity Index score between the 2 groups over 12 weeks will serve as the primary *** outcomes include improvements in other clinical,quality of life,and economic outcomes over 24 *** adverse events will be ***:Results from this trial may provide evidence regarding the clinical effectiveness,safety,and cost-effectiveness of electroacupuncture compared to manual acupuncture for patients with axSpA,and guide implementation into clinical *** of this trial include the lack of patient blinding,use of a repeated measures design,and possible variation in acupuncture technique amongst the various Traditional Chinese Medicine practitioners.

关键词： axial spondyloarthritis complementary and alternative medicine electroacupuncture randomized controlled trial Traditional Chinese Medicine

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