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Utilization of pH-driven methods to fortify nanoemulsions with multiple polyphenols

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Food Science and Human Wellness 2024年第4期13卷 1943-1950页

作者： Hualu Zhou Bingjing Zheng David julian McClements Department of Food Science and Technology College of Agricultural and Environmental SciencesUniversity of GeorgiaGriffinGA 30223USA Biopolymers and Colloids Laboratory Department of Food ScienceUniversity of MassachusettsAmherstMA 01003USA Department of Food Science&Bioengineering Zhejiang Gongshang UniversityHangzhou 310018China

Simple but effective methods are required to incorporate multiple bioactive polyphenols into delivery systems to increase their dispersibility,stability and *** developed and tested three p Hdriven protocols for creating nanoemulsions loaded with multiple lipophilic *** protocols differed in how the different polyphenols were incorporated into the *** impact of these three methods on the formation,properties,and gastrointestinal fate of nanoemulsions loaded with curcumin,resveratrol,and quercetin was *** three methods produced nanoemulsions with similar initial particle properties:droplet diameters(0.15,0.16,and 0.15μm)and zeta-potentials(–59,–58,and–58 m V),***,the average encapsulation efficiencies(82%,88%,and 61%),gastrointestinal stabilities(83%,97%,and 29%)and bioaccessibilities(77%,90%,and 73%)for curcumin,resveratrol,and quercetin were somewhat *** particular,more quercetin degradation occurred using the approach that held it under alkaline conditions for extended *** general,the p H-driven method provides researchers with a versatile approach of incorporating multiple polyphenols with different characteristics into functional food and beverages using a simple and inexpensive method.

关键词： Polyphenols pH-Driven encapsulation Nanoemulsions Gastrointestinal fate Functional foods

Solvation Effects on the Dielectric Constant of 1 M LiPF6 in Ethylene Carbonate:Ethyl Methyl Carbonate 3:7

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Energy & Environmental Materials 2024年第1期7卷 253-256页

作者： julian Self Nathan T.Hahn Kristin A.Persson Department of Chemical Engineering Polytechnique MontrealMontrealQC H3T 1J4Canada Department of Materials Science and Engineering University of CaliforniaBerkeleyCA 94720USA Energy Technologies Area Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Material Physical and Chemical Sciences CenterSandia National LaboratoriesAlbuquerqueNM 87185USA

We report the dielectric constant of 1 M LiPF_(6)in EC:EMC 3∶7 w/w(ethylene carbonate/ethyl methyl carbonate)in addition to neat EC:EMC 3∶7 w/*** three Debye relaxations,the static permittivity value,or dielectric constant,is extrapolated to 18.5,which is compared to 18.7 for the neat solvent *** EC solvent is found to strongly coordinate with the Li^(+)cations of the salt,which results in a loss of dielectric contribution to the ***,the small amplitude and large uncertainty in relaxation frequency for EMC cloud definitive identification of the Li^(+)solvation ***,the loss of the free EC permittivity contribution due to Li^(+)solvation is almost completely balanced by the positive contribution of the associated LiPF_(6)salt,demonstrating that a significant quantity of dipolar ion pairs exists in 1 M LiPF_(6)in EC:EMC 3∶7.

关键词： batteries dielectric relaxation spectroscopy electrolytes

The biosynthesis of alarm pheromone in the wheat aphid Rhopalosiphum padi is regulated by hormones via fatty acid metabolism

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Journal of Integrative Agriculture 2024年第7期23卷 2346-2361页

作者： Chengxian Sun Yaoguo Qin julian Chen Zhengxi Li Department of Entomology/Ministry of Agriculture Key Laboratory for Monitoring and Environment-friendly Control of Crop Pests College of Plant ProtectionChina Agricultural UniversityBeijing 100193China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China

Aphids are major insect pests in agriculture and forestry *** attacks by natural enemies,many aphids release an alarm pheromone to protect their *** most aphids,the main component of the aphid alarm pheromone(AAP)is the sesquiterpene hydrocarbon(E)-β-farnesene(EβF).However,the mechanisms behind its biosynthesis and regulation remain poorly *** this study,we used the bird cherry–oat aphid Rhopalosiphum padi,which is an important wheat aphid,to investigate the regulatory mechanisms of EβF *** results showed that EβF biosynthesis occurs during the mature embryo period and the molting period of the 1st-and 2nd-instar *** provide the prerequisite material for EβF production and *** on transcriptome sequencing,RNAi analysis,hormone treatments,and quantitative measurements,we found that the biosynthesis of EβF utilizes acetyl coenzyme A produced from fatty acid degradation,which can be suppressed by juvenile hormone but it is promoted by 20-hydroxyecdysone through the modulation of fatty acid *** is the first systemic study on the modulation of EβF production in *** results of our study provide insights into the molecular regulatory mechanisms of AAP biosynthesis,as well as valuable information for designing potential aphid control strategies.

关键词： (E)-β-farnesene critical period for biosynthesis fatty acid metabolism juvenile hormone 20-hydroxyecdysone

Population dynamics of the tropical oyster Magallana bilineata(Mollusca,Bivalvia,Ostreidae)in Mengkabong Bay,Tuaran,Malaysia

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Aquaculture and Fisheries 2024年第2期9卷 295-305页

作者： Joanna W.Doinsing julian Ransangan Politeknik Sandakan Sabah Education HubBatu 10Jalan Sungai BatangSandakanSabah90000Malaysia Borneo Marine Research Institute Universiti Malaysia SabahJalan UMSKota Kinabalu88400Malaysia

Knowledge about the population dynamics within a specific spatial area is vital for the effective planning and management of important fishery *** parameters,including the asymptotic length(L∞),growth coefficient(K),mortalities(Z,F,and M),recruitment pattern,exploitation level(E),and yield per recruit(Y’/R),of the tropical oyster Magallana bilineata in Mengkabong Bay,Tuaran,Malaysia were analyzed by using the FiSAT software,using on the monthly shell length-frequency data collected from April 2019 to March 2020.A total of 435 oysters with shell lengths ranging from 3.64 to 11.16 cm were *** water temperature,salinity,dissolved oxygen,hydrogen ion concentration(pH),and chlorophyll concentration were measured at 29.0-33.7◦C,26.68-35.74 psμ,3.18-6.99 mg/L,6.57-8.29 and 1.51-98.93μg/L,*** logarithmic relationship between the length and weight of Log W=1.9055 Log L+0.1049(R2=0.5431)with exponent b of 1.9055 for combined sexes showed a negative allometric growth(b<3),indicating that the oysters in Mengkabong Bay are *** management measures have been proposed to promote high meat growth,including the use of genetically selected seeds,selection of new farming sites and adoption of grow-out methods that favour high meat *** length(L∞)and growth coefficient(K)of the von Bertalanffy Growth Formula(VBGF)for *** were estimated at 12.13 cm and 1.00 yr􀀀1,*** theoretical ages at length zero(t0)(0.0487)were estimated by substituting L∞and K in Pauly’s *** sizes attained by *** were 3.76,5.04,6.13,7.05,7.83,and 8.49 cm at the end of 2,4,6,8,10,and 12 months,*** calculated growth performance index(φ)for *** in Mengkabong Bay was 2.168,while the estimated lifespan was 3 *** recruitment pattern was observed year-round,with higher recruitment activities in September-October 2019 and January *** total mortality(Z)was analyzed using the length-converted

关键词： Crassostrea iredalei Length-weight relationship Growth parameters Recruitment Exploitation

Multi-point temperature measurements in packed beds using phosphor thermometry and ray tracing simulations

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Particuology 2024年第2期85卷 77-88页

作者： Guangtao Xuan Mirko Ebert Simson julian Rodrigues Nicole Vorhauer-Huget Christian Lessig Benoit Fond Institute of Fluid Dynamics and Thermodynamics OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany Institute of Simulations and Graphics OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany Institute of Process Engineering OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany ONERA The French Aerospace LabDepartment of AerodynamicsAeroelasticity and Aeroacoustics(DAAA)Paris-Saclay University8rue des VertugadinsMeudon92190France

Packed bed reactors are commonly found in the process industry,for example in flame-assisted calci-nation for cement *** the heat transfer inside the bed is essential for process control,product quality and energy *** we propose a technique to determine the internal temperature distribution of packed beds based on a combination of lifetime-based phosphor ther-mometry,ray tracing simulations,and assimilation of temperature data using finite element heat transfer *** establish and validate the technique,we considered a reproducible regular packing of 6 mm diameter aluminum spheres,with one of the spheres in the top layer being electrically *** a sphere inside the packing is coated with thermographic phosphors and excitation light is directed to-wards the packing,luminescence from the coated sphere exits the packed bed after multiple reflection and the sphere's temperature can be *** measurements showed that the temper-ature obtained by phosphor thermometry is independent of the luminescent sphere *** imaging the luminescence on a camera,the luminescence distribution in recorded image depended,however,on the position of the ***,in setups with multiple phosphor-coated spheres,their signals can be separated using a least squares *** demonstrate the approach using a setup with three luminescent spheres and validated the temperature readings against thermocouple *** obtain the spatial signatures for individual sphere positions required for the least squares fit,ray tracing simulations were *** provide an efficient alternative to single sphere measurements that are only practical for regular spherical packed ***-point measurements were used as input to a finite element heat transfer simulations to determine parameters such as particle-to-particle air gap *** these,the full temperature distribution inside the bed could be assimilated from the meas

关键词： Packed beds Phosphor thermometry Ray tracing Heat transfer simulation Data assimilation

Machine learning for predicting the outcome of terminal ballistics events

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Defence Technology（防务技术） 2024年第1期31卷 14-26页

作者： Shannon Ryan Neeraj Mohan Sushma Arun Kumar AV julian Berk Tahrima Hashem Santu Rana Svetha Venkatesh Applied Artificial Intelligence Institute(A2I2) Deakin University75 Pigdons RdWaurn PondsVIC3216Australia

Machine learning(ML) is well suited for the prediction of high-complexity,high-dimensional problems such as those encountered in terminal *** evaluate the performance of four popular ML-based regression models,extreme gradient boosting(XGBoost),artificial neural network(ANN),support vector regression(SVR),and Gaussian process regression(GP),on two common terminal ballistics’ problems:(a)predicting the V50ballistic limit of monolithic metallic armour impacted by small and medium calibre projectiles and fragments,and(b) predicting the depth to which a projectile will penetrate a target of semi-infinite *** achieve this we utilise two datasets,each consisting of approximately 1000samples,collated from public release *** demonstrate that all four model types provide similarly excellent agreement when interpolating within the training data and diverge when extrapolating outside this *** extrapolation is not advisable for ML-based regression models,for applications such as lethality/survivability analysis,such capability is *** circumvent this,we implement expert knowledge and physics-based models via enforced monotonicity,as a Gaussian prior mean,and through a modified loss *** physics-informed models demonstrate improved performance over both classical physics-based models and the basic ML regression models,providing an ability to accurately fit experimental data when it is available and then revert to the physics-based model when *** resulting models demonstrate high levels of predictive accuracy over a very wide range of projectile types,target materials and thicknesses,and impact conditions significantly more diverse than that achievable from any existing analytical *** with numerical analysis tools such as finite element solvers the ML models run orders of magnitude *** provide some general guidelines throughout for the development,application,and reporting of ML models in terminal ballist

关键词： Machine learning Artificial intelligence Physics-informed machine learning Terminal ballistics Armour

Symptomatic bradycardia in tuberculosis-related giant bullae(vanishing lung syndrome):A case report

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Asian Pacific Journal of Tropical Medicine 2024年第9期17卷 425-428页

作者： Reynard Laysandro Jessie julian Mila Meha Resley Ongga Mulia Mikha Nazamta Yusfiatuzzahra School of Medicine and Health Science Atma Jaya Catholic University of Indonesia JakartaIndonesia Faculty of Medicine and Veterinary Medicine University of Nusa Cendana East Nusa TenggaraIndonesia Faculty of Medicine Trisakti University JakartaIndonesia

Rationale:Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana *** occurrence of giant bullae can also be linked to infections,particularly tuberculosis in tropical *** concerns:A 26-year-old male complained of weakness,severe vomiting,and reduced breathlessness when lying on the left *** had a history of pulmonary tuberculosis two years ***:Symptomatic bradycardia in tuberculosis-related giant ***:The patient was recommended to undergo an elective bullectomy,but he decided not to proceed with the *** sulfate was administered to alleviate symptoms of bradycardia,while a standardized anti-tuberculosis regimen were started for the next six ***:Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate,the patient achieved hemodynamic stability,opting against bullectomy despite residual symptoms of *** six months of antituberculosis therapy notably alleviated symptoms without requiring ***:Increasing intrathoracic pressure can also be caused mechanically by giant *** symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is *** this case,symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention。

关键词： Bradycardia Infected giant bullae Tuberculosis Vanishing lung syndrome

Single-shot 3D incoherent imaging with diffuser endoscopy

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Light(Advanced Manufacturing) 2024年第2期5卷 64-74页

作者： julian Lich Tom Glosemeyer Jürgen Czarske Robert Kuschmierz Laboratory of Measurement and Sensor System Technique TU DresdenGermany Competence Center for Biomedical Computational Laser Systems(BIOLAS) TU DresdenGermany Else Kroner Fresenius Center for Digital Health(EKFZ) TU DresdenGermany Cluster of Excellence Physics of Life TU DresdenGermany

Minimally invasive endoscopy offers a high potential for biomedical imaging ***,conventional fiberoptic endoscopes require lens systems which are not suitable for real-time 3D ***,a diffuser is utilized for passively encoding incoherent 3D objects into 2D speckle *** networks are employed for fast computational image reconstruction beyond the optical memory *** this paper,we demonstrate single-shot 3D incoherent fiber imaging with keyhole access at video *** the diffuser fiber endoscope for fluorescence imaging is promising for in vivo deep brain diagnostics with cellular resolution.

关键词： Endoscopy Diffuser Deep learning Coherent fiber bundle Multicore fiber Neural networks Fiber optics Speckle patterns Fluorescence imaging

Adaptive optimisation of explosive reactive armour for protection against kinetic energy and shaped charge threats

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Defence Technology（防务技术） 2024年第10期40卷 1-12页

作者： Philipp Moldtmann julian Berk Shannon Ryan Andreas Klavzar Jerome Limido Christopher Lange Santu Rana Svetha Venkatesh University of the Federal Armed Forces Hamburg Holstenhofweg 85Hamburg 22043Germany Applied Artificial Intelligence Institute(A2I2) Deakin University75 Pigdons RdWaurn PondsVIC 3216Australia French-German Research Institute of Saint-Louis(ISL) 5 Rue de General CassagnouSaint-Louis 68300France ABSTRAO 16 Rue de Isaac NewtonPlaisance-du-Touch 31830France

We evaluate an adaptive optimisation methodology,Bayesian optimisation(BO),for designing a minimum weight explosive reactive armour(ERA)for protection against a surrogate medium calibre kinetic energy(KE)long rod projectile and surrogate shaped charge(SC)*** perform the optimisation using a conventional BO methodology and compare it with a conventional trial-and-error approach from a human expert.A third approach,utilising a novel human-machine teaming framework for BO is also *** for the optimisation is generated using numerical simulations that are demonstrated to provide reasonable qualitative agreement with reference *** human-machine teaming methodology is shown to identify the optimum ERA design in the fewest number of evaluations,outperforming both the stand-alone human and stand-alone BO *** a design space of almost 1800 configurations the human-machine teaming approach identifies the minimum weight ERA design in 10 samples.

关键词： Terminal ballistics Armour Explosive reactive armour Optimisation Bayesian optimisation