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Rheologi.al and stabi.i.y analysi. of cement pastes i.corporati.g si.i.a-based wastes

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Parti.uology 2024年第6期89卷 144-152页

作者： julia da Rosa Marti.s Janaíde Cavalcante Rocha Dachami. Hotza Luci.no Senff Graduate Program i. Materi.ls Sci.nce and Engi.eeri.g(PPGMAT) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program i. Ci.i. Engi.eeri.g(PPGEC) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Graduate Program i. Chemi.al Engi.eeri.g(POSENQ) Federal University of Santa Catarina(UFSC)Florianópolis88040-900SCBrazil Department of Mobi.i.y Engi.eeri.g Federal University of Santa Catarina(UFSC)Joinville89219-600SCBrazil

Thi. study i.vesti.ates the i.fluence of waste characteri.ti.s,especi.lly zeta potenti.l,on the properti.s of cement pastes and *** focus i. to evaluate the i.pact of the zeta potenti.l of cement parti.les and waste materi.ls on the sedi.entati.n speed,rheology,and hardeni.g ti.e of stabi.i.ed cement *** Cement i. F 40,retarder addi.i.e,si.i.a,and fly ash were used i. the *** pastes were prepared,and duri.g the stabi.i.ati.n peri.d,thei. rheologi.al properti.s and pH were *** zeta potenti.l and sedi.entati.n speed of the cement and waste parti.les were measured at the pH that the pastes presented duri.g the enti.e stabi.i.ati.n *** the stabi.i.ati.n peri.d,the pastes were subjected to the hardeni.g ti.e *** zeta potenti.l analyses revealed di.erse values for the di.ferent powder types,wi.h the cement parti.les exhi.i.i.g a zeta potenti.l of−3.0 mV,the si.i.a parti.les exhi.i.i.g−10.5 mV,and the fly ash parti.les exhi.i.i.g−20.3 *** i.fluence of the hi.h zeta potenti.l modulus was observed on the sedi.entati.n speed,wi.h the soluti.n contai.i.g fly ash exhi.i.i.g a speed of 40.01μm/s,whereas the soluti.n contai.i.g only cement exhi.i.ed a speed of 99.38μm/*** the pastes,the results i.di.ate that the presence of fly ash parti.les wi.h a si.ni.i.antly negati.e zeta potenti.l led to a 16%reducti.n i. hardeni.g ti.e compared to parti.les wi.h a lower modulus of zeta *** tests showed that the i.clusi.n of fly ash parti.les prevented the formati.n of *** the zeta potenti.l i.fluenced agglomerate formati.n and hardeni.g ti.e,i. was found to have no effect on yi.ld stress or vi.cosi.y.

关键词： Wastes Zeta potenti.l Setti.g ti.e Rheometry

Woody plant taxonomi.,functi.nal,and phylogeneti. di.ersi.y decrease along elevati.nal gradi.nts i. Andean tropi.al montane forests:Envi.onmental fi.teri.g and arri.al of temperate taxa

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Plant Di.ersi.y 2024年第4期46卷 491-501页

作者： Gui.lermo Bañares-de-Di.s Manuel J.Macía Gabri.l Arellano Íñi.o Granzow-de la Cerda julia Vega-álvarez i.zi.r Arnelas Carlos i.Espi.osa Norma Sali.as Lui. Cayuela Departamento de Bi.logía y Geología Física y Química InorgánicaUniversidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain Departamento de Bi.logía Área de BotánicaUniversidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Centro de i.vesti.aci.n en Bi.di.ersi.ad y Cambi. Global(Ci.C-UAM) Universidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Ecology and Evoluti.nary Bi.logy University of MichiganAnn ArborMI 48109USA Oi.obi. LLC ***AlbuquerqueNM87120USA Real Jardín Botáni.o–CSi. Plaza Murillo 2MadridES-28014Spain Departamento de Bi.logía Ani.al EcologíaParasitologíaEdafología y Química AgrícolaUniversidad de SalamancaCalle Donantes de Sangre s/nSalamancaES-37007Spain Departamento de Bi.di.ersi.ad Ecología y EvoluciónUniversidad Complutense de MadridCalle JoséAntonio Nováis 12Ciudad UniversitariaES-28040Spain Departamento de Ci.nci.s Bi.lógi.as y Agropecuari.s Universidad Técnica Particular de LojaA.P.11-01-608 LojaEcuador Secci.n Quími.a Pontificia Universidad Católica del PerúA.P.Lima 32LimaPeru ECi School of Geography and EnvironmentUniversity of OxfordOX13QYOxfordshireUnited Kingdom i.sti.uto de i.vesti.aci.n en Cambi. Global(i.CG-URJC) Universidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain

Mountai.s are paramount for explori.g bi.di.ersi.y patterns due to the mosai. of topographi.s and cli.ates encompassed over short *** research has tradi.i.nally focused on taxonomi. di.ersi.y when i.vesti.ati.g changes along elevati.nal gradi.nts,but other facets should be *** fi.st ti.e,we si.ultaneously assessed elevati.nal trends i. taxonomi.,functi.nal,and phylogeneti. di.ersi.y of woody plants i. Andean tropi.al montane forests and explored thei. underlyi.g ecologi.al and evoluti.nary *** i.vesti.ati.n covered four transects(traversi.g ca.2200 m a.s.l.) encompassi.g 114 plots of 0.1 ha across a broad lati.udi.al range(ca.10°).Usi.g Hi.l numbers to quanti.y abundance-based di.ersi.y among 37,869 i.di.i.uals we observed a consi.tent decrease i. taxonomi.,functi.nal,and phylogeneti. di.ersi.y as elevati.n i.creased,although the decrease was less pronounced for hi.her Hi.l *** excepti.n was a sli.ht i.crease i. phylogeneti. di.ersi.y when domi.ant speci.s were *** decrease i. taxonomi. and functi.nal di.ersi.y mi.ht be attri.uted to an envi.onmental fi.teri.g process towards hi.hlands,where the i.creasi.gly harsher condi.i.ns exclude speci.s and functi.nal ***,the di.ferences i. steepness decrease between Hi.l orders suggest that rare speci.s di.proporti.nately contri.ute to functi.nal *** phylogeneti. di.ersi.y the shi.ti.g elevati.nal trend between Hi.l orders i.di.ates a greater than previ.usly consi.ered i.fluence i. central Andean hi.hlands of tropi.al lowlands ori.i.ated speci.s wi.h strong ni.he conservati.m relati.e to di.tantly related temperate *** could be explai.ed by a decreasi.g presence and abundance of temperate,extratropi.al taxa towards the central Andes relati.e to northern or southern Andes,where they are more prevalent.

关键词： Alti.udi.al gradi.nts Andes Envi.onmentalﬁlteri.g Out of the Tropi.al Lowlands Functi.nal rari.y Tropi.al Ni.he Conservati.m

Parasi.es of the li.er:A global problem?

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World Journal of Gastroenterology 2024年第30期30卷 3554-3559页

作者： Vladi.lav V Tsukanov Alexander V Vasyuti. julia L Tonki.h Cli.i.al Department of the Di.esti.e System Pathology of Adults and Chi.dren Federal Research Center“Krasnoyarsk Science Center”of the Siberian Branch of the Russian Academy of SciencesScientific Research Institute of Medical Problems of the NorthKrasnoyarsk 660022Russia

Parasi.i. li.er di.eases can be caused by trematodes,cestodes,nematodes,and *** pathology i. si.ni.i.ant because mi.li.ns of people i. di.ferent parts of the world have li.er parasi.es,whi.h can mani.est themselves i. the development of i.flammati.n,li.er cysts,cholecysti.i.,choleli.hi.si.,pancreati.i. and li.er ci.rhosi. that are often threateni.g thei. *** i.ternati.nal Agency for Research on Cancer consi.ers three speci.s of trematodes,Schi.tosoma haematobi.m,Opi.thorchi. vi.erri.i.and Clonorchi. si.ensi.,to be *** modern exami.ati.n methods,i. some cases i.cludi.g extensi.e screeni.g of large populati.ns,are requi.ed for di.gnosi.g li.er *** of parasi.i. li.er di.eases i. di.ferenti.ted and can i.volve a combi.ati.n of surgi.al and therapeuti. *** i. no doubt that the cli.i.al and epi.emi.logi.al scale allows one to regard parasi.i. li.er di.eases as a global healthcare problem.

关键词： Li.er Parasi.es Epi.emi.logy Di.gnosi. Cli.i.s Treatment Echi.ococcosi. Opi.thorchi.si. Fasci.li.si. Schi.tosomi.si.

Beyond wrecki.g a wall:revi.i.i.g the concept of blood–brai. barri.r breakdown i. i.chemi. stroke

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Neural Regenerati.n Research 2025年第7期20卷 1944-1956页

作者： julia Casti.lo-González Elena González-Rey i.sti.ute of Parasi.ology and Bi.medi.i.e Lopez-Neyra(i.BLN) CSICPT SaludGranadaSpain

The blood–brai. barri.r consti.utes a dynami. and i.teracti.e boundary separati.g the central nervous system and the peri.heral *** ti.htly modulates the i.n transport and nutri.nt i.flux,whi.e restri.ti.g the entry of harmful factors,and selecti.ely li.i.i.g the mi.rati.n of i.mune cells,thereby mai.tai.i.g brai. *** the well-establi.hed associ.ti.n between blood–brai. barri.r di.rupti.n and most neurodegenerati.e/neuroi.flammatory di.eases,much remai.s unknown about the factors i.fluenci.g i.s physi.logy and the mechani.ms underlyi.g i.s ***,the role of blood–brai. barri.r breakdown i. the translati.nal fai.ure underlyi.g therapi.s for brai. di.orders i. just starti.g to be *** revi.w ai.s to revi.i. thi. concept of“blood–brai. barri.r breakdown,”delvi.g i.to the most controversi.l aspects,prevalent challenges,and knowledge gaps concerni.g the lack of blood–brai. barri.r *** movi.g beyond the oversi.pli.ti. di.hotomy of an“open”/“bad”or a“closed”/“good”barri.r,our objecti.e i. to provi.e a more comprehensi.e i.si.ht i.to blood–brai. barri.r dynami.s,to i.enti.y novel targets and/or therapeuti. approaches ai.ed at mi.i.ati.g blood–brai. barri.r ***,i. thi. revi.w,we advocate for consi.eri.g the di.erse ti.e-and locati.n-dependent alterati.ns i. the blood–brai. barri.r,whi.h go beyond ti.ht-juncti.n di.rupti.n or brai. endotheli.l cell breakdown,i.lustrated through the dynami.s of i.chemi. stroke as a case *** thi. explorati.n,we seek to underscore the complexi.y of blood–brai. barri.r dysfuncti.n and i.s i.pli.ati.ns for the pathogenesi. and therapy of brai. di.eases.

关键词： blood–brai. barri.r di.rupti.n drug deli.ery i.chemi. stroke neuroi.flammati.n ti.ht-juncti.ns

Molecular i.si.hts i.to cli.i.al tri.ls for i.mune checkpoi.t i.hi.i.ors i. colorectal cancer:Unravelli.g challenges and future di.ecti.ns

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World Journal of Gastroenterology 2024年第13期30卷 1815-1835页

作者： Samantha Sharma Naresh Si.gh Ani.a Ahmed Turk i.abella Wan Akshay Gutti.onda julia Li.y Dong Xi.na Zhang Mateusz Opyrchal Department of Medi.al and Molecular Geneti.s Indiana University School of MedicineIndianapolisIN 46202United States Di.i.i.n of Hematology/Oncology Department of MedicineIndiana University School of MedicineIndianapolisIN 46202United States Melvi. and Bren Si.on Comprehensi.e Cancer Center Indiana University School of MedicineIndianapolisIN 46202United States

Colorectal cancer(CRC)i. a complex di.ease wi.h di.erse eti.logi.s and cli.i.al *** consi.erable progress i. development of CRC therapeuti.s,challenges remai. regardi.g the di.gnosi. and management of advanced stage metastati. CRC(mCRC).i. parti.ular,the fi.e-year survi.al rate i. very low si.ce mCRC i. currently rarely *** the past decade,cancer treatment has si.ni.i.antly i.proved wi.h the i.troducti.n of cancer i.munotherapi.s,speci.i.ally i.mune checkpoi.t *** ai.ed at blocki.g i.mune checkpoi.ts such as PD-1,PD-L1,and CTLA-4 target i.hi.i.ory pathways of the i.mune system,and thereby enhance anti.tumor *** therapi.s thus have shown promi.i.g results i. many cli.i.al tri.ls alone or i. *** effi.acy and safety of i.munotherapy,ei.her alone or i. combi.ati.n wi.h CRC,have been i.vesti.ated i. several cli.i.al *** tri.ls,i.cludi.g KEYNOTE-164 and CheckMate 142,have led to Food and Drug Admi.i.trati.n approval of the PD-1 i.hi.i.ors pembroli.umab and ni.olumab,respecti.ely,for the treatment of pati.nts wi.h unresectable or metastati. mi.rosatelli.e i.stabi.i.y-hi.h or defi.i.nt mi.match repai. ***,these drugs benefi. only a small percentage of pati.nts,wi.h the benefi.s of i.munotherapy remai.i.g elusi.e for the vast majori.y of CRC *** thi. end,pri.ary and secondary resi.tance to i.munotherapy remai.s a si.ni.i.ant i.sue,and further research i. necessary to opti.i.e the use of i.munotherapy i. CRC and i.enti.y bi.markers to predi.t the *** revi.w provi.es a comprehensi.e overvi.w of the cli.i.al tri.ls i.volvi.g i.mune checkpoi.t i.hi.i.ors i. *** underlyi.g rati.nale,challenges faced,and potenti.l future steps to i.prove the prognosi. and enhance the li.eli.ood of successful tri.ls i. thi. fi.ld are di.cussed.

关键词： Colorectal cancer i.mune checkpoi.t i.hi.i.ors Cli.i.al tri.ls i.munotherapy Mi.rosatelli.e i.stabi.i.y Mi.rosatelli.e stabi.i.y DNA mi.match repai.

Adverse events related to physi.al restrai.t use i. i.tensi.e care uni.s: A revi.w of the li.erature

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Journal of i.tensi.e Medi.i.e 2024年第3期4卷 318-325页

作者： Sebasti.n Berger Pascale Grzonka Si.on A.Amacher Sabi.a Hunzi.er Anja i.Frei.Raoul Sutter Cli.i. for i.tensi.e Care Department of Acute MedicineUniversity Hospital BaselBaselSwitzerland Medi.al Communi.ati.n and Psychosomati. Medi.i.e University Hospital BaselBaselSwitzerland Medi.al faculty University of BaselBaselSwitzerland Department of Cli.i.al Research University of BaselBaselSwitzerland

Physi.al restrai.ts are wi.ely used and accepted as protecti.e measures duri.g treatment i. i.tensi.e care uni. (i.U). Thi. revi.w of the li.erature summari.es the adverse events and outcomes associ.ted wi.h physi.al restrai.t use, and the ri.k factors associ.ted wi.h thei. use duri.g treatment i. the i.U. The PubMed, Scopus, and Google Scholar databases were screened usi.g predefi.ed search terms to i.enti.y studi.s pertai.i.g to adverse events and/or outcomes associ.ted wi.h physi.al restrai.t use, and the factors associ.ted wi.h thei. use i. adult pati.nts admi.ted to the i.U. A total of 24 arti.les (i.cludi.g 6126 pati.nts) that were publi.hed between 2006 and 2022 were i.enti.i.d. The descri.ed adverse events associ.ted wi.h physi.al restrai.t use i.cluded ski. i.juri.s, subsequent deli.i.m, neurofuncti.nal i.pai.ment, and a hi.her rate of post-traumati. stress di.order. Subsequent deli.i.m was the most frequent adverse event to be reported. No alternati.e measures to physi.al restrai.ts were di.cussed, and only one study reported a standardi.ed protocol for thei. use. Although physi.al restrai.t use has been reported to be associ.ted wi.h adverse events (i.cludi.g neurofuncti.nal i.pai.ment) i. the li.erature, the avai.able evi.ence i. li.i.ed. Although causali.y cannot be confi.med, a defi.i.e associ.ti.n appears to exi.t. Our fi.di.gs suggest that i. i. essenti.l to i.prove awareness regardi.g thei. adverse i.pact and opti.i.e approaches for thei. detecti.n, management, and preventi.n usi.g protocols or checkli.ts.

关键词： Physi.al restrai.t i.tensi.e care uni. Deli.i.m Compli.ati.n Adverse event

Barosi.usi.i. due to routi.e weather changes:A cross-secti.nal analysi. of publi. websi.es

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World Journal of Otorhi.olaryngology-Head and Neck Surgery 2024年第1期10卷 18-23页

作者： James C.Campbell julia E.Cani.k Phi.i. G.Chen Ralph Abi.Hachem Davi. W.Jang Department of Head and Neck Surgery&Communi.ati.n Sci.nces Duke University School of MedicineDurhamNorth CarolinaUSA Duke Uni.ersi.y School of Medi.i.e DurhamNorth CarolinaUSA Department of Otolaryngology-Head and Neck Surgery University of Texas Health Science Center San AntonioSan AntonioTexasUSA

Background:Si.usi.i. i. a common di.gnosi. that can be erroneously associ.ted wi.h routi.e weather‐related barometri. pressure *** actuali.y,these pressure changes li.ely exacerbate mi.rai.e headaches,whi.h can cause faci.l pai. and pressure rather than true si.us ***:The present study sought to characteri.e the representati.n of both si.usi.i. and mi.rai.e i. associ.ti.n wi.h barometri. pressure changes across websi.es on the ***:An i.ternet search for relevant terms was conducted,and content of the resulti.g pages was assessed for associ.ti.ns between weather‐related pressure changes and ei.her si.usi.i. or *** i. reported results across di.ferent subtypes of i.ternet sources were *** pri.ary outcomes measured were(1)whether a gi.en medi. source associ.ted barometri. weather changes wi.h si.usi.i.,(2)whether that source associ.ted barometri. weather changes wi.h mi.rai.e,and(3)treatment opti.ns offered by that ***:Of the 116 i.cluded webpages,36(31.03%)associ.ted si.usi.i. and routi.e barometri. pressure *** these,10(27.77%)were otolaryngology practi.e ***‐seven webpages(57.76%)associ.ted mi.rai.e and routi.e barometri. pressure *** these,nonotolaryngology webpages were more li.ely to report thi. ***:Otolaryngology practi.e si.es were observed to be the most frequent professi.nal medi.al resource reporti.g the unsubstanti.ted clai. that routi.e barometri. pressure changes are associ.ted wi.h *** sources were more li.ely to li.k weather‐related pressure changes to *** results suggest that opportuni.i.s exi.t for otolaryngology practi.e si.es to educate pati.nts about nonrhi.ogeni. headache eti.logi.s.

关键词： acute rhi.osi.usi.i. balloon si.us di.ati.n headache mi.rai.e si.usi.i.

ENSO i.pacts on li.ter stocks and water holdi.g capaci.y i. secondary forests i. eastern Amazoni.

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： julia i.abella de Matos Rodri.ues Walmer Bruno Rocha Marti.s Vi.tor Perei.a de Oli.ei.a Myri.m Suelen da Si.va Wanzerley Héli. Bri.o dos Santos Júni.r Franci.co de Assi. Oli.ei.a Graduate Program i. Forestry Sci.nces Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural Uni.ersi.y of Amazoni. Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural Uni.ersi.y of Amazoni. Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil Nati.nal i.sti.ute of Amazoni. Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the i.pacts of cli.ate change,there i. the i.tensi.i.ati.n of phenomena such as the El Ni.o South-ern Osci.lati.n(ENSO)responsi.le for El Ni.o and La Ni.***,understandi.g thei. effects on the functi.nal pro-cesses of forests i. ***,thi. study evaluated the effects of ENSO on li.ter stock and water holdi.g capac-i.y(WHC)i. a successi.nal forest i. eastern *** occurred i. peri.ds wi.h the most rai.fall i. El Ni.o(2019)and least i. La Ni.a(2021)*** permanent plots were used to sample *** effects were evi.ent for WHC,hi.her duri.g El Ni.***,thi. i.fluence was not clear for li.ter,as only i. the rai.y season effects were *** was a posi.i.e correlati.n of WHC wi.h preci.i.ati.n and humi.i.y,whi.e li.ter stocks were negati.ely correlated wi.h temperature and wi.d *** the subject of thi. study requi.es long-term assessments,preli.i.ary results suggests that,dependi.g on the i.tensi.y of ENSO,forest functi.nal processes can be strongly i.pacted and *** conclusi.n rei.forces warni.gs by the sci.nti.i. communi.y about the i.pacts of cli.ate change on the mai.tenance of li.ter stocks,decomposi.i.n and,consequently,the bi.geochemi.al cycle and essenti.l ecosystem servi.es for the mai.tenance of Amazoni. *** need to develop long-term research to understand the effects of cli.ati. change on li.ter stocks and water holdi.g capaci.y i. hi.hli.hted,especi.lly i. Amazoni..

关键词： Seasonali.y Cli.ate change Successi.n ecosystem Bi.geochemi.al cycle Amazoni. bi.di.ersi.y

Otolaryngology resi.ency program factors associ.ted wi.h female resi.ent representati.n

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World Journal of Otorhi.olaryngology-Head and Neck Surgery 2024年第1期10卷 7-11页

作者： julia E.Cani.k James C.Campbell Charles R.Woodard Lars J.Gri.m Ali.sa M.Colli.s Duke Uni.ersi.y School of Medi.i.e DurhamNorth CarolinaUSA Department of Head and Neck Surgery&Communi.ati.n Sci.nces Duke University School of MedicineDurhamNorth CarolinaUSA Department of Radi.logy Duke University School of MedicineDurhamNorth CarolinaUSA

Objecti.e:Female representati.n i. the fi.ld of otolaryngology i. *** i. the fi.st poi.t at whi.h medi.al school graduates speci.li.e i. a chosen fi.ld and thus represents an opportuni.y to recrui. and trai. more female *** study sought to i.enti.y program factors associ.ted wi.h greater female representati.n among resi.ent ***:Departmental websi.es of all 124 otolaryngology resi.ency programs i. the Uni.ed States and Puerto Ri.o were exami.ed for a li.t of *** programs wi.h a resi.ent roster avai.able,the genders of resi.ents,faculty,program di.ectors,and chai.persons were *** and ci.y populati.n for each program was also recorded,as was female resi.ent *** were compared usi.g Pearson Chi.squared uni.ari.te ***:1,632 resi.ents and 2,605 faculty were i.cluded i. the analysi. of 109 *** medi.n female resi.ent representati.n was 40%.Programs wi.h larger faculty si.es,more female faculty,and urban locati.n were associ.ted wi.h an above‐medi.n female resi.ent *** wi.h a larger resi.ency cohort approached si.ni.i.ance regardi.g above‐medi.n female resi.ent *** female faculty representati.n,program di.ector gender,chai.person gender,and US regi.n were not associ.ted wi.h vari.ti.n i. female resi.ent ***:Greater female otolaryngology resi.ency representati.n was associ.ted wi.h programs havi.g an urban locati.n and greater numbers of female and total *** was also li.ely that a larger resi.ent cohort si.e may affect female resi.ent *** proporti.ns of female faculty,program di.ector,and chai.person gender,as well as the US regi.n,were not associ.ted wi.h vari.ti.n i. female resi.ent gender representati.n.

关键词： gender program di.ector recrui.ment resi.ency trai.i.g